Application of methylene blue -vitamin C –N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trialResearch article Published on 2020-10-012022-10-05 Journal: European journal of pharmacology [Category] 임상, 치료법, [키워드] Activation acute respiratory syndrome Administered application approved cascade catastrophic cause clinical trial complications contribute coronavirus COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients Critical Critically ill cysteine cytokine drug FDA FIVE healthy individuals hypoxia ICU induce Inflammatory inflammatory state Interrupting kill Macrophage macrophage activation mechanism metabolite Methylene blue microbial N-acetyl cysteine Nitrate nitric oxide other diseases oxidative stress Pathogenesis Patient patients phenotype pro-inflammatory protocol significantly increased Stress survival rate the disease the patient therapeutic effect therapeutic option Treatment vicious cycle Vitamin C were measured [DOI] 10.1016/j.ejphar.2020.173494 [Article Type] Research article
Glucose-6-Phosphate Dehydrogenase Deficiency: An Actionable Risk Factor for Patients with COVID-19?Research article Published on 2020-10-012022-10-05 Journal: Archives of medical research [Category] SARS, 변종, [키워드] affected African Asian Asymptomatic coronavirus COVID-19 COVID-19 infection deficiency dehydrogenase drug drugs element Factor G6PD Genetic glucose-6-phosphate dehydrogenase Glucose-6-phosphate deydrogenase deficiency hemolytic anemia individual individuals Infection Latin Mutation outcome oxidative stress Patient populations prevalent risk factor treat viral infection X-linked [DOI] 10.1016/j.arcmed.2020.06.006 [Article Type] Research article
COVID-19 and non-alcoholic fatty liver disease: Two intersecting pandemicsReview Published on 2020-10-012023-07-11 Journal: European Journal of Clinical Investigation [Category] SARS, [키워드] Fatty liver Mitochondria nitrosative stress oxidative stress SARS-CoV-2 [DOI] 10.1111/eci.13338 PMC 바로가기 [Article Type] Review
Can phytotherapy with polyphenols serve as a powerful approach for the prevention and therapy tool of novel coronavirus disease 2019 (COVID-19)?Review Published on 2020-10-012023-06-14 Journal: American journal of physiology. Endocrinology and [Category] MERS, SARS, [키워드] complications microbiota oxidative stress polyphenols viral infection [DOI] 10.1152/ajpendo.00298.2020 PMC 바로가기 [Article Type] Review
Oxidative Stress and Inflammation in COVID-19-Associated Sepsis: The Potential Role of Anti-Oxidant Therapy in Avoiding Disease ProgressionReview Published on 2020-09-292022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome antioxidant Avoiding Clinical characteristics clinical trial contribute contributing to coronavirus coronavirus disease COVID-19 COVID-19 patient COVID-19 progression COVID-19 severity Critically ill Cytokine storm effort ICU identify IMPROVE Inflammation intensive care unit involved mechanism molecular molecular mechanism NETosis outbreak oxidative stress Pathogenesis pathogenesis of SARS-CoV-2 phenotype Potential prevent disease progression progression pyroptosis reduce role SARS-CoV-2 SARS-CoV-2 infected patients Sepsis severity therapeutic therapy understanding [DOI] 10.3390/antiox9100936 PMC 바로가기 [Article Type] Review
Ganoderma Lucidum from Red Mushroom Attenuates Formaldehyde-Induced Liver Damage in Experimental Male Rat ModelArticle Published on 2020-09-272023-08-29 Journal: Biology [Category] E형 간염, [키워드] Ganoderma lucidum formaldehyde Inflammation liver oxidative stress [DOI] 10.3390/biology9100313 PMC 바로가기 [Article Type] Article
Glutathione Supplementation as an Adjunctive Therapy in COVID-19Review Published on 2020-09-252022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] caused coronavirus disease COVID-19 COVID-19 patients Cytokine storm Cytokines decrease dysregulated Effect Epidemiology Evidence glutathione GSH HIV Human immunodeficiency virus hypercoagulable IFN-α IFN-β IL-6 immune response inhibit interferon Mortality multi-organ failure Necrosis oxidative stress Pathogenesis patients pulmonary disease the disease TNF-α TNF-α Transmission Treatment Tuberculosis viral replication [DOI] 10.3390/antiox9100914 PMC 바로가기 [Article Type] Review
Mitochondrial Glutathione: Recent Insights and Role in DiseaseReview Published on 2020-09-242022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] aging Alzheimer Alzheimer’s disease antioxidant catalyzed cell death coronavirus disease COVID-19 Defense Diabetic diabetic nephropathy Disease progression Diseases disorder drug enzyme Gender glutathione highlight insight Mitochondria mitochondrial mitochondrial dysfunction Modification nephropathy oxidative oxidative stress pathology reaction reactive oxygen specy recent Research role ROS Signaling steatohepatitis Topic Treatment [DOI] 10.3390/antiox9100909 PMC 바로가기 [Article Type] Review
Oxidative Stress, Proton Fluxes, and Chloroquine/Hydroxychloroquine Treatment for COVID-19Review Published on 2020-09-212022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] acute respiratory distress Alter alteration Antiviral medications ARDS cause caused Chloroquine Coagulation complex COVID-19 COVID-19 disease drug Evidence form HCQ Health Hydroxychloroquine Hyperinflammatory implicated increasingly induce lipid peroxidation malarial parasite morbidity Observational data oxidative oxidative stress pathophysiological phospholipid bilayer promote proton proton fluxes reactive oxygen species reactive oxygen specy reactivity ROS SARS-CoV-2 subcellular syndrome treatments for COVID-19 [DOI] 10.3390/antiox9090894 PMC 바로가기 [Article Type] Review
An elevated 8-isoprostaglandin F2 alpha (8-iso-PGF2α) in COVID-19 subjects co-infected with malaria말라리아에 동시 감염된 COVID-19 피험자에서 상승된 8-이소프로스타글란딘 F2 알파(8-iso-PGF2α)Research Published on 2020-09-212022-09-10 Journal: The Pan African Medical Journal [Category] MERS, SARS, 말라리아, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse outcome adverse outcomes African Alpha antioxidant antioxidants cause Co-infection coronavirus coronavirus 2 country COVID-19 COVID-19 patient COVID-19 patients cytokine Cytokine storm Diagnosis Diseases elevated ELISA free radical Free radicals Healthcare system healthy control implicated increase in Increased malaria management naïve Nigeria oxidative stress Pathogenesis Patient progression Research respiratory Result SARS-CoV-2 patients serum levels severe acute respiratory syndrome Coronavirus severity significant decrease statistically significant study participant Study participants subject utilization [DOI] 10.11604/pamj.2020.37.78.25100 PMC 바로가기 [Article Type] Research