Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groupsResearch Article Published on 2006-10-042022-10-28 Journal: BMC Microbiology [Category] Coronavirus, [키워드] acute respiratory syndrome adaptive addition Amino acid changes in characterized contribute coronavirus Course CoV detected different domain Epidemic epidemiological Evolution found greater group groups heptad repeat hosts human host humans membrane fusion occurred outbreak Phylogenetic tree positive Positive selection proportion Protein RBD receptor residue Result reveal S gene S protein SARS-CoV selected selective selective pressure selective sweep spike gene strain subsequent the S protein Transmission two group two groups Variation viral adaptation [DOI] 10.1186/1471-2180-6-88 PMC 바로가기 [Article Type] Research Article
Molecular Epidemiology of SARS-associated Coronavirus, BeijingResearch Published on 2005-09-012022-10-31 Journal: Emerging Infectious Diseases [Category] Coronavirus, [키워드] amplified amplified products Beijing Characteristics clinical sample Cluster collected coronavirus different dominant Epidemics geographic location Guangdong Host immune pressure isolate loci molecular Molecular epidemiology motif Mutation nucleotide Patient patients reported RT-PCR RT-PCR, research SARS-CoV selective sequence Sequencing Severe acute respiratory syndrome single nucleotide variation SNV SNVs to define Variation viral adaptation were used [DOI] 10.3201/eid1109.040773 PMC 바로가기 [Article Type] Research