Epidemiological and clinical course of 483 patients with COVID-19 in Wuhan, China: a single-center, retrospective study from the mobile cabin hospitalOriginal Article Published on 2020-07-182022-10-31 Journal: European Journal of Clinical Microbiology & Infect [Category] Coronavirus, MERS, SARS, [키워드] Characteristics Clinical course COVID-19 COVID-19 outbreak dead described Deterioration diagnosed discharge discharged disease feasible hospital intensive care Intervention Isolation mobile cabin hospital outbreak outcome outcomes Patient patients with COVID-19 provide Retrospective study severe cases single-center supplementary material transferred treated treated patient virus Wuhan [DOI] 10.1007/s10096-020-03927-3 PMC 바로가기 [Article Type] Original Article
Serum IgM against SARS-CoV-2 correlates with in-hospital mortality in severe/critical patients with COVID-19 in Wuhan, ChinaPriority Research Paper Published on 2020-07-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] adverse event antibody Antibody Response ARDS Asia change Clinical outcome cohort study conducted coronavirus disease correlated COVID-19 COVID-19 progression declined described global pandemic high mortality rate higher risk IgG IgM illness onset Immunoglobulin in-hospital mortality incidence intensive care IQR median outcome Patient patients patients with COVID-19 performed respiratory retrospective SARS-CoV-2 Sepsis serum severe acute respiratory syndrome coronavirus 2 Shock significantly single-center survivor were measured Wuhan Wuhan, China [DOI] 10.18632/aging.103417 PMC 바로가기 [Article Type] Priority Research Paper
No Statistically Apparent Difference in Antiviral Effectiveness Observed Among Ribavirin Plus Interferon-Alpha, Lopinavir/Ritonavir Plus Interferon-Alpha, and Ribavirin Plus Lopinavir/Ritonavir Plus Interferon-Alpha in Patients With Mild to Moderate Coronavirus Disease 2019: Results of a Randomized, Open-Labeled Prospective StudyPharmacology Published on 2020-07-142022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] acute respiratory syndrome adverse event adverse events Analysis Antiviral antiviral therapy Antiviral treatment baseline calculated clinical clinical trial Combination comparable conducted coronavirus coronavirus disease COVID-19 COVID-19 patient difference Effectiveness effectiveness and safety enrolled Follow-up group IFN-α incidence include intention-to-treat interferon-alpha Interferon-α laboratory characteristics Lopinavir/ritonavir median interval Mild Mild to moderate COVID-19 Moderate COVID-19 Mortality negativity no significant difference nucleic acid Observed outcome pandemic Patient patients with SARS-CoV-2 proportion Prospective Prospective clinical trial Randomized regimen Registration Result ribavirin SARS-CoV-2 SARS-CoV-2 nucleic acid severe cases significant increase significantly higher single-center Spread statistically study period the median three groups [DOI] 10.3389/fphar.2020.01071 PMC 바로가기 [Article Type] Pharmacology
Relationship of chest CT score with clinical characteristics of 108 patients hospitalized with COVID-19 in Wuhan, ChinaResearch Published on 2020-07-142022-10-28 Journal: Respiratory Research [Category] COVID-19, [키워드] abnormal coagulation Affect affected appear association Blood C-reactive protein case sery changes in characterized Chest computed tomography Chest CT Chest CT score Clinical characteristics Clinical findings coagulation function Comorbidities COVID-19 COVID-19 infection COVID-19 patient CRP CRP level demographics determine digestive system disease erythrocyte sedimentation rate ESR examined exhibited glucocorticoid hospitalized patient Inflammation Inflammatory mediators information lung parenchyma Lungs lymphocyte objective occurred outbreak Patient patients patients hospitalized positive procalcitonin reduce reduced relationship Result retrospective sensitivity severity of COVID-19 single-center spread to systemic inflammation systemic inflammatory systemic inflammatory response therapy Tongji Hospital Tongji Medical College Treatment WBC were recorded White blood cell with COVID-19 Wuhan, China [DOI] 10.1186/s12931-020-01440-x PMC 바로가기 [Article Type] Research
Neurological Manifestations in Critically Ill Patients With COVID-19: A Retrospective StudyNeurology Published on 2020-07-102022-11-01 Journal: Frontiers in Neurology [Category] COVID-19, [키워드] age analyzed antibody Brain case sery Central nervous system Cerebrovascular disease collected Comorbidity Complication coronavirus disease COVID-19 Critically ill Critically ill patient critically ill patients delirium demographic exhibited hemoglobin Ill Injury intensive care involved Laboratory male manifestation multiple organ neurological Neurological complication neurological manifestations neuromuscular disease neuromuscular diseases Patient physician Prevalence retrospective significantly higher single-center stroke Symptom the mean Tongji Hospital Treatment with COVID-19 Wuhan, China [DOI] 10.3389/fneur.2020.00806 PMC 바로가기 [Article Type] Neurology
Transpulmonary pressure in SARS-CoV-2-associated acute respiratory distress syndrome: a single-center observational studyResearch Letter Published on 2020-07-092022-11-01 Journal: Critical Care [Category] Coronavirus, SARS, [키워드] acute respiratory distress single-center [DOI] 10.1186/s13054-020-03129-5 PMC 바로가기 [Article Type] Research Letter
High Inflammatory Burden: A Potential Cause of Myocardial Injury in Critically Ill Patients With COVID-19Cardiovascular Medicine Published on 2020-07-072022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] addition Admission age analyzed assessment cause chronic Clinical characteristics cohort study Comorbidity confidence interval correlation COVID-19 COVID-19 patient Cox regression critical patients Critically ill patient death demographic develop diagnosed enrolled exceeded failure had more hazard ratio high mortality high mortality rate High-sensitivity C-reactive protein IL-10 IL-6 IL-8 Ill In-ICU mortality incidence independent risk factor Inflammation Inflammatory Injury Laboratory tests limits Logistic regression median Mortality myocardial injury novel coronavirus disease Occurrence Odds ratio Older outcome Patient patients patients with COVID-19 Physiology plasma Plasma level positively correlated Potential receptor retrospective risk factor score significantly higher single-center smoking statistically suggested the mean TNF-α tumor necrosis factor-α two group with COVID-19 [DOI] 10.3389/fcvm.2020.00128 PMC 바로가기 [Article Type] Cardiovascular Medicine
Monitoring and Management of Home-Quarantined Patients With COVID-19 Using a WeChat-Based Telemedicine System: Retrospective Cohort StudyOriginal Paper Published on 2020-07-022022-10-30 Journal: Journal of Medical Internet Research [Category] COVID-19, SARS, [키워드] addition alleviate changes in condition conditions conducted coronavirus disease COVID-19 Critical Cross-infection Deterioration diagnostic Disease progression Dyspnea evaluate evaluated extracorporeal membrane oxygenation Fever healthy help home quarantine hospital Hospitalization Hospitalized identify individual infected with COVID-19 lack large cohort Local management media medical resource Mild symptom MONITOR monitoring Most patient objective Patient patients patients with COVID-19 persistence physician Prevent progressed progression progressive COVID-19 progressive COVID-19 patients quarantine quarantine management assessment reduce Result Retrospective study risk single-center study period Support Symptom Symptoms Telemedicine telemedicine system the disease Tongji Hospital Treatment was used Wuhan, China [DOI] 10.2196/19514 PMC 바로가기 [Article Type] Original Paper
Treatment strategies of hospitalized patients with coronavirus disease-19Research Paper Published on 2020-06-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] Antiviral treatment Arbidol case sery China Combination coronasvirus disease-19 Coronavirus disease-19 COVID-19 Critical Critical disease diagnosed discharge rate discharged disease epidemiological and clinical characteristics Final Follow-up glucocorticoid Hospital stay hospitalized patient infected patients Lopinavir median Mild outbreak outside Wuhan oxygen Patient patients phosphate Prognosis retrospective single-center Support Transmission Treatment strategies Ventilation Wuhan [DOI] 10.18632/aging.103370 PMC 바로가기 [Article Type] Research Paper
Prognosis analysis of patients with mental disorders with COVID-19: a single-center retrospective studyResearch Paper Published on 2020-06-302022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] affecting Analysis analyzed baseline characteristics center Clinical symptoms COVID-19 cured Deceased Dementia diagnosed with COVID-19 Factor Final indicated Inflammatory response intensive care laboratory parameter Mental disorder Mental Disorders mortality rate neutrophil Patient patients patients with COVID-19 Prognosis prognosis of patient reducing mortality Research Retrospective study selected serum significantly higher significantly increased single-center the patient WBC with COVID-19 Wuhan [DOI] 10.18632/aging.103371 PMC 바로가기 [Article Type] Research Paper