Prevalence

[키워드] absence ACVRL1 analyzed animals Antigen autosomal dominant autosomal dominant disorder auxiliary Bacteria balance blood monocyte blood monocytes C57BL/6 cell line characterized conditions contribute deficiency described develop differentiation disorder dominant dysplasia Endoglin endotoxin ENG explain expressed expression foci function help hemorrhage hemorrhages Hereditary Hereditary hemorrhagic telangiectasia homeostasis human cell human macrophages immune immune response Impaired in vitro in vivo increased survival Infection infection rate Infectious disease Infectious diseases Inflammation internal organs knock-out Laboratory leukemic leukemic cell Lineage Macrophage macrophages malformation mice monocyte monocyte-macrophage Monocytes Mortality mouse macrophages multisystemic patients Peripheral blood peripheral blood monocytes peritoneal macrophage peritoneal macrophages peritonitis Phagocytic activity predisposition Prevalence rare disease receptor recruited Rendu-Osler-Weber syndrome response responsible show Signaling surface antigen syndrome target gene Target genes TGF-β TGF-β1 transmembrane protein triggered type I up-regulation Vascular vessel wall was reduced Weber syndrome wild-type
[DOI] 10.1371/journal.pgen.1005935 PMC 바로가기 [Article Type] Research Article