Re-Thinking the Role of Government Information Intervention in the COVID-19 Pandemic: An Agent-Based Modeling AnalysisArticle Published on 2020-12-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] Accuracy aggravate build COVID-19 COVID-19 pandemic diffusion dissemination Effectiveness Factor Government Infectious disease information information blocking information disclosing information intervention Intervention modeling opposite outbreak preference public health reducing risk of infection role social network virus [DOI] 10.3390/ijerph18010147 PMC 바로가기 [Article Type] Article
Efficacy of Traditional Chinese Medicine, Maxingshigan-Weijing in the management of COVID-19 patients with severe acute respiratory syndrome: A structured summary of a study protocol for a randomized controlled trial중증 급성 호흡기 증후군이 있는 COVID-19 환자 관리에 대한 중국 전통 의학 Maxingshigan-Weijing의 효능: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-12-232022-08-31 Journal: Trials [Category] MERS, SARS, 임상, 치료제, [키워드] 1:1 acute respiratory syndrome acute respiratory syndrome coronavirus addition administration Affiliated Hospital age allergic allergies anorexia anti-bacterial Anti-viral anticipated Anxiety Arm asked Asymptomatic automatically aversion blinded Blinding Blood tinged blood tinged sputum both groups Care carried center checklist Chenpi chest pain chest X-ray Chinese Chinese Clinical Trial Registry Chinese herbal medicines clinical clinical symptom clinical trials clinically Cold comparator Patients composed control group Controlled trial coronavirus cough COVID-19 COVID-19 patient criteria critical patient critical patients defined diarrhea disease Diseases dissemination distension Dizziness dry mouth dysphoria effective Efficacy element Eligible patients ephedra exclusion criteria expectoration female Fever Follow-up four-point scale Gypsum H1N1 H1N1 influenza headache hematopoietic system Herba Ephedra herbal medicine hospital IBM IBM Corp IMPROVE improvement in both group include Inclusion inclusion and exclusion criteria inclusion criteria individual Influenza Informed consent Inpatient Insomnia Kaplan-Meier method kidney Kidney function lactation less liver log-rank test malaise male management Maxingshigan-weijing mechanical ventilation Medicine Melon Mild mild clinical symptoms multicenter multiple organ failure muscular nasal nasal obstruction nausea nausea and vomiting negative test nucleic acid number objective open Open-label oral administration outcome participant Patient patients Peach pharyngalgia Pneumonia positive Pregnancy previous study Primary outcome Professor proportion protocol Radix random random allocation random number generator randomisation randomised Randomized Randomized controlled trial randomly divided receive recruited registry reported researcher respiratory Respiratory failure respiratory symptom Sample size SARS-CoV-2 SARS-CoV-2 nucleic acid Scoring second secondary Secondary outcomes Semen sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity Shock Shortness of breath statistical analysis Statistical power Statistics status Study protocol suffering supplementary material supportive care survival survival time sweating Symptom symptomatic Symptoms System TCM temperature test results the median therapy total score Traditional Traditional Chinese medicine treated Treatment trial protocol Trial registration Trichosanthe Trichosanthes Kirilowii university USA Version virus pneumonia vomiting website wheezing Winter Withdrawal [DOI] 10.1186/s13063-020-04970-3 PMC 바로가기 [Article Type] Letter
Effects of rapid recruitment and dissemination on Covid-19 mortality: the RECOVERY trial신속한 모집 및 보급이 Covid-19 사망률에 미치는 영향: RECOVERY 시험Opinion Article Published on 2020-12-232022-09-11 Journal: F1000Research [Category] MERS, 임상, [키워드] adaptive Analysis COVID-19 decreased mortality demonstrated Dexamethasone dissemination Effect eligible patient Eligible patients hospitalised patient Hospitalised patients Hydroxychloroquine Mortality oxygen pandemic Patient randomised controlled trial RECOVERY trial recruited recruitment reduce reducing mortality significantly speed supplemental oxygen Treatment Trial ventilator [DOI] 10.12688/f1000research.25842.2 PMC 바로가기 [Article Type] Opinion Article
A Mobile Serious Game About the Pandemic (COVID-19 – Did You Know?): Design and Evaluation StudyOriginal Paper Published on 2020-12-222022-10-30 Journal: JMIR Serious Games [Category] COVID-19, [키워드] analytics analyzed blocks Brazil Card Care conducted coronavirus correlation coefficient COVID-19 Critical develop Digital health dissemination e-learning error rate Follow-up game Gamification Google Health HTML5 identity increase in Infection informatics information Interaction introduced knowledge linear Mask measure media methodology mHealth Mobile mobile apps objective pandemic Prevent prevention of COVID-19 programming public health reached recommendation Result SARS-CoV-2 serious game social distancing Specific Spread the disease Topic Transmission treatment for COVID-19 TypeScript university virus website [DOI] 10.2196/25226 PMC 바로가기 [Article Type] Original Paper
Full-length genome characterization and phylogenetic analysis of SARS-CoV-2 virus strains from Yogyakarta and Central Java, IndonesiaBioinformatics Published on 2020-12-212022-10-28 Journal: PeerJ [Category] COVID-19, [키워드] Analysis appear applied Asia circulating clade Cluster collected Complete COVID-19 COVID-19 patient COVID-19 situation D614G mutation dataset dissemination distribution Europe full-length full-length genome sequence Genome GISAID Hospitalized Illumina Miseq Indonesia NC_045512.2 Next-generation sequencing NGS Patient Phylogenetic analysis reference genome Region Result retrieved SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 virus SARS-CoV-2 virus strain sequence severity variant virus virus genome virus sample was performed WGS Whole genome sequencing [DOI] 10.7717/peerj.10575 PMC 바로가기 [Article Type] Bioinformatics
Extracellular RNA as a Versatile DAMP and Alarm Signal That Influences Leukocyte Recruitment in Inflammation and InfectionCell and Developmental Biology Published on 2020-12-182022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] Activation activity administration alarm arteriogenesis Bacteria Blood cells bypasses cardiovascular disease circulating cofactor condition Contact COVID-19 DAMP DAMPs danger-associated molecular patterns defense process demonstrated dissemination docking edema effective endothelial endothelial cells Endothelium ENhance Extracellular extracellular nucleic acids growth help histone host cell immune defense implicated in vitro in vivo include Inflammation Inflammatory inflammatory macrophages inflammatory vascular diseases influence initiate innate immune response Interaction intracellular material Invasion investigated Ischemia leukocyte limit microbial microbial infection microRNA molecular Non-coding RNAs non-toxic nucleic acid pro-thrombotic promote provide provoke Reactions recruitment regimen RNA RNase1 Safe signal subsequent therapeutic thrombosis tissue damage Vascular Vascular injury VEGF vessel vessel wall viral infection viral particle virus virus infection while wound healing [DOI] 10.3389/fcell.2020.619221 PMC 바로가기 [Article Type] Cell and Developmental Biology
Effects of curcumin-piperine co-supplementation on clinical signs, duration, severity, and inflammatory factors in patients with COVID-19: a structured summary of a study protocol for a randomised controlled trialCOVID-19 환자의 임상 징후, 기간, 중증도 및 염증 요인에 대한 커큐민-피페린 공동 보충제의 효과: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-12-172022-09-10 Journal: Trials [Category] 임상, [키워드] 1:1 age analyses anticipated Anticoagulant anticoagulant drugs assigned Blinding calculated Capsule clinical Clinical signs Clinical symptoms clinical trial clinical trials Co-supplementation completion conducted control group coronavirus coronavirus disease COVID-19 Curcumin Curcumin-piperine Diagnosis dinner disease Disease duration dissemination double-blind drugs Effect Efficacy element Enrollment exclusion criteria female Gender hospital hospital ward Hospital wards ICU include independent Inflammatory factor inflammatory factors inflammatory mediator Inflammatory mediators Inpatient intensive care intensive care unit Intervention Iran less male maltodextrin matching placebo mediators Medical Sciences number objective outcome Outpatient packaged Parallel Arm participant Patient patients PCR test piperine Placebo placebo-controlled placebo-controlled clinical trial protocol provided randomised randomised controlled trial Randomized Randomly receive Registered registration date registry researcher Sample size sealed sensitivity sequence severity status Stratification Study protocol supplementary material title total sample size Trial Trial registration turmeric university Version Warfarin website [DOI] 10.1186/s13063-020-04924-9 PMC 바로가기 [Article Type] Letter
Mechanisms of Atomization from Rotary Dental Instruments and Its MitigationResearch Reports Published on 2020-12-162022-10-29 Journal: Journal of Dental Research [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome aerosol aerosol-generating procedure appear Atomization burr Care Characteristics Contact coronavirus coronavirus disease dental dental drill described dispersal dissemination distribution droplet droplets Effectiveness Efficiency Elimination emission Generalizability imaging infection control instrument lack mechanism Mitigation modify Multiple New occur parameter potential risk Probability produced reduced reduction in resulting SARS-CoV-2 threshold Transmission variable [DOI] 10.1177/0022034520979644 PMC 바로가기 [Article Type] Research Reports
Underreporting of Death by COVID-19 in Brazil’s Second Most Populous StatePublic Health Published on 2020-12-152022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] average Brazil cause caused clinically country COVID-19 COVID-19 deaths COVID-19 pandemic database death discrepancy dissemination Frequency Government health system increase in Minas Gerais MOST Pneumonia portal Prevent Quantitative analysis registry Research reveal SARI deaths SARS-CoV-2 second shown state These data Transparency Underreporting was performed [DOI] 10.3389/fpubh.2020.578645 PMC 바로가기 [Article Type] Public Health
Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens포르말린 고정 파라핀 포매 표본에서 SARS-CoV 및 SARS-CoV-2 검출을 위한 면역조직화학 및 in situ hybridization 개발Article Published on 2020-12-142022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] addition against SARS-CoV animal animal models antibody Antigen antigen retrieval method applied causative agent caused coronavirus coronavirus pathogenesis COVID-19 demonstrated detect determine development dissemination evaluated expressing facilitate FFPE flexibility formalin formalin-fixed paraffin-embedded IHC immunohistochemistry infected cell infected cells Live virus MERS Microscopy non-infected cell non-infected cells nucleoprotein paraffin positive control probe protocol public health Research RNA SARS-CoV SARS-CoV spike protein SARS-CoV-2 SARS-CoV-2 viral specimen spike gene Spike protein tested therapeutic Therapeutics tissues utility Vaccine Viral virus virus detection [DOI] 10.1038/s41598-020-78949-0 PMC 바로가기 [Article Type] Article