Factors indicating intention to vaccinate with a COVID-19 vaccine among older U.S. adults미국 노년층에서 COVID-19 백신 접종 의사를 나타내는 요인Clinical Trial Published on 2021-05-242022-08-13 Journal: PLoS ONE [Category] 임상, [키워드] African American Algorithm black clinical study Complete COVID-19 complication COVID-19 complications COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines decision demographic data education Efficacy effort enrolled evaluated Factor forest Gender Health help highlight immunization IMPROVE income Intention lack less Logistic regression majority Older Older adults outcome positive result Random forest receive reported Result Study participants vaccinate vaccination Vaccine Variability [DOI] 10.1371/journal.pone.0251963 PMC 바로가기 [Article Type] Clinical Trial
A Study of Older Adults’ Mental Health across 33 Countries during the COVID-19 PandemicArticle Published on 2021-05-112022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] age Anxiety Asia being Characteristics coronavirus country COVID-19 COVID-19 complication COVID-19 pandemic death deleterious effect demographics Depression Europe examined facilitate healthy help impacted impacts implication International Latin America media mental health mental health service Older Older adults pandemic participant predicted Psychological recruitment Region reported separated severe symptom Treatment [DOI] 10.3390/ijerph18105090 PMC 바로가기 [Article Type] Article
MSC-derived exosomes carrying a cocktail of exogenous interfering RNAs an unprecedented therapy in era of COVID-19 outbreakReview Published on 2021-04-222022-10-30 Journal: Journal of Translational Medicine [Category] COVID-19, SARS, [키워드] acute respiratory distress antiviral immune response candidate clinical status COVID-19 COVID-19 complication COVID-19 outbreak COVID-19 therapy ENhance Exosome Exosomes Gene therapy Immune suppression immunomodulatory involved lung management Mesenchymal stem cells miRNA MSCs pandemic Pathogenesis platform Prevent regenerative regimen RNA RNA interference SARS-CoV-2 SARS-CoV-2 pathogenesis siRNA syndrome target targets the SARS-CoV-2 therapeutic therapeutic option therapeutic strategy therapy Treatment viral spread Virus life cycle [DOI] 10.1186/s12967-021-02840-3 PMC 바로가기 [Article Type] Review
Suicide Thoughts and Attempts in the Norwegian General Population during the Early Stage of the COVID-19 OutbreakArticle Published on 2021-04-132022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] addition age alcohol analyzed Attempted suicide collected coronavirus COVID-19 COVID-19 complication COVID-19 outbreak early stage Factor Logistic regression analysis media Norway pandemic Population population survey Prevalence recruited reported risk Risk factors Sociodemographic Stage Suicidal behavior Suicide thought variable [DOI] 10.3390/ijerph18084102 PMC 바로가기 [Article Type] Article
COVID-19-associated inflammatory syndrome in an adult woman with unexplained multiple organ failure: staying vigilant for COVID-19 complications as the pandemic surges설명할 수 없는 다발성 장기 부전이 있는 성인 여성의 COVID-19 관련 염증 증후군: 대유행이 급증함에 따라 COVID-19 합병증에 대한 경계 유지Case Reports Published on 2021-04-122022-09-11 Journal: BMJ case reports [Category] MERS, 진단, 치료기술, [키워드] Antibody testing center children clinician Control COVID-19 COVID-19 complication defined Diagnosis disease control disease severity exposure to identify Inflammation Inflammatory management medical management MIS-C organ organ damage Organ failure pandemic PCR testing positive prevention SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-COV-2 infection serious complication Shock Stress syndrome thought virus [DOI] 10.1136/bcr-2021-242034 PMC 바로가기 [Article Type] Case Reports
Genetics Insight for COVID-19 Susceptibility and Severity: A ReviewCOVID-19 감수성 및 심각도에 대한 유전학적 통찰: 검토Review Published on 2021-04-012022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 유전자 메커니즘, [키워드] ABO ACE2 affecting allele alleles association Asymptomatic broad spectrum CCR9 Clinical course clinical manifestation clinical manifestations coronavirus coronavirus disease COVID-19 COVID-19 complication COVID-19 complications COVID-19 severity COVID-19 susceptibility CXCR6 cytokine Cytokine storm disease disease susceptibility expression FCGR2A FYCO1 genetic background Genetic variant genetic variants genetics GWAS HLA HLA-A Host IL17A IL1B IL1R1 IL1RN IL6 Infectious disease Infectious diseases insight inter-individual loci LZTFL1 mechanism outcome pathway Population receptor receptors reported review Risk factors SARS-CoV-2 several variants severity SLC6A20 SNV susceptibility the disease thrombosis thrombosis) TMPRSS2 TNF Variability variant variants Venous thrombosis with COVID-19 XCR1 [DOI] 10.3389/fimmu.2021.622176 PMC 바로가기 [Article Type] Review
Safety of disease-modifying treatments in SARS-CoV-2 antibody-positive multiple sclerosis patientsSARS-CoV-2 항체 양성 다발성 경화증 환자에서 질병 조절 치료의 안전성Article Published on 2021-04-012022-09-12 Journal: Multiple sclerosis and related disorders [Category] MERS, SARS, 진단, [키워드] 7-point ordinal scale acute respiratory syndrome addition anti-SARS-CoV-2 Asymptomatic Clinical characteristics complications conducted coronavirus Coronavirus disease 2019 COVID-19 COVID-19 complication COVID-19 severity COVID-19 symptom criteria disease disease severity DMT drug Effect Hospitalization Hypothesis Immune cell Infection inhibit lack maintain mild COVID-19 symptoms Multiple multiple sclerosis Patient patients physician positive raise receiving required Roche Safe Safety SARS CoV-2 SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 IgG SARS-COV-2 infection serology serology testing severe COVID-19 Support symptomatic treated Treatment was performed [DOI] 10.1016/j.msard.2021.102754 PMC 바로가기 [Article Type] Article
Association Between Risk Factors for Complications From COVID-19, Perceived Chances of Infection and Complications, and Protective Behavior in the USResearch Published on 2021-03-312022-10-29 Journal: JAMA Network Open [Category] COVID-19, SARS, [키워드] 95% CI activities activity adjusted Adults age America Behavior blood pressure center chance collected Complication complications conditions Control COVID-19 COVID-19 complication cross-sectional analysis cross-sectional survey death determine elevated exposure Factor finding Hospitalization Importance Infection infection risk Lung disease majority Masks measure modify objective Older Older age outcome participant Perceived Point ranged recognize reduce Relevance remained reported Result risk risk factor Risk factors setting severe complication Sociodemographic characteristics susceptibility susceptible the mean understanding wearing while women [DOI] 10.1001/jamanetworkopen.2021.3984 PMC 바로가기 [Article Type] Research
Pre-existing conditions are associated with COVID-19 patients’ hospitalization, despite confirmed clearance of SARS-CoV-2 virusResearch Paper Published on 2021-03-232022-10-31 Journal: EClinicalMedicine [Category] COVID-19, [키워드] Acute kidney injury Anemia Cardiac arrhythmia clearance clearance of SARS-CoV-2 Cohort cohorts Comorbidity Complication condition conducted COVID-19 COVID-19 complication COVID-19 patient COVID-19 patients finding Follow-up funding highlight Hospitalization Hospitalized hospitalized COVID-19 patient positive presenting Record Research Retrospective analysis Retrospective study Risk factors SARS-CoV-2 PCR test significantly supported viral clearance virus with COVID-19 [DOI] 10.1016/j.eclinm.2021.100793 PMC 바로가기 [Article Type] Research Paper
Improving the Understanding of the Immunopathogenesis of Lymphopenia as a Correlate of SARS-CoV-2 Infection Risk and Disease Progression in African Patients: Protocol for a Cross-sectional StudyProtocol Published on 2021-03-042022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] “COVID-19 African alleles amplification analyses Analysis Apoptosis apoptotic pathways association Bax BCL-2 BCL2L12 Biomarker carried caspase 3 categories caused CD4 collected Comorbidity complete blood count Concentration country COVID-19 COVID-19 complication COVID-19 pandemic cross-sectional Cytokine storm determinant determine Disease progression distribution DNA EDTA ELISA enrolled enzyme-linked immunosorbent expected expression expression level flow cytometry Frequency genetic determinants Genomic DNA genotyped genotypes genotypic genotyping Haplotype Hardy-Weinberg equilibrium Health health system help Hospitalized hospitalized patient Hypovitaminosis D Identifier Immunopathogenesis IMPROVE Improving include individual infected patients infected with SARS-CoV-2 information Lagos Linkage disequilibrium Lymphocyte count lymphopenia MONITOR Nigeria objective Other outcome participant Participants Patient PCR performed phenotypic polymerase chain polymorphism Prevalence Prognosis questionnaire R statistical software report Repurposed drug Result reverse transcribed reverse transcription PCR risk stratification RNA RNA sample RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2–positive Sequencing serum sample serum vitamin D severe infections soluble Fas ligand Stratification study outcome T cell assay T lymphocyte Total Travel Treatment treatment regimen understanding vascular cell adhesion VDR venous blood Vitamin D receptor Vitamin D status with COVID-19 [DOI] 10.2196/21242 PMC 바로가기 [Article Type] Protocol