A central role for PBP2 in the activation of peptidoglycan polymerization by the bacterial cell elongation machinery박테리아 세포 신장 기계에 의한 펩티도글리칸 중합의 활성화에서 PBP2의 중심 역할Research Article Published on 2018-10-182022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin activate activated Activation activation pathway activities activity Analysis antibiotic Author Bacteria bacterial cell biogenesis Cell Cell elongation cell wall cell wall synthesis changes in complex complexes component conserved Control control cell crosslinking cytokinesis cytoskeletal filament cytoskeletal filaments determine disrupt enzymatic activity enzyme Enzymes Escherichia coli Evidence exhibited Genetic genetic evidence glycan glycan polymerase glycan polymerases hyperactivate identify in vitro in vivo inactivated morphogenic MreB Mutation osmotic lysis pathway PBP PBP2 PBPs penicillin penicillin-binding protein penicillin-binding proteins polymerase Prevent promote PROTECT provide remained required Rod system RodA stimulate the cell uncrosslinked variant [DOI] 10.1371/journal.pgen.1007726 PMC 바로가기 [Article Type] Research Article
Septin‐regulated actin dynamics promote Salmonella invasion of host cells세프틴 조절 액틴 역학이 살모넬라의 숙주 세포 침입을 촉진한다.Article Published on 2018-07-262024-08-19 Journal: Cellular Microbiology [Category] 살모넬라증, [키워드] Actin Bacterial infection formin myosin II Salmonella enterica serovar Typhimurium Septin [DOI] 10.1111/cmi.12866 PMC 바로가기
First report of Cryptosporidium parvum in a dromedary camel calf from Western AustraliaArticle Published on 2018-06-262023-06-21 Journal: Acta parasitologica [Category] 조류인플루엔자, [키워드] 18S Actin Camel cryptosporidium GP60 [DOI] 10.1515/ap-2018-0049
Early events during human coronavirus OC43 entry to the cellArticle Published on 2018-05-082022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, [키워드] Actin Affect Cell cellular receptor Cluster confocal microscopy Coronaviridae family determine entry routes event Features functional human coronavirus OC43 Infection infection process Molecular biology recognize Research RNA viruses specificity susceptible cell Vesicle virulence virus [DOI] 10.1038/s41598-018-25640-0 PMC 바로가기 [Article Type] Article
Wnt5A Signaling Promotes Defense Against Bacterial Pathogens by Activating a Host Autophagy CircuitWnt5A 신호전달은 숙주 자가포식 회로를 활성화하여 세균 병원체에 대한 방어를 촉진합니다.Original Research Published on 2018-04-092024-08-01 Journal: Frontiers in immunology [Category] 폐렴구균 감염증, [키워드] Actin autophagy bacterial clearance COPD Macrophage pathogen Sepsis Wnt5a [DOI] 10.3389/fimmu.2018.00679 PMC 바로가기 [Article Type] Original Research
Porcine Hemagglutinating Encephalomyelitis Virus Enters Neuro-2a Cells via Clathrin-Mediated Endocytosis in a Rab5-, Cholesterol-, and pH-Dependent MannerVirus-Cell Interactions Published on 2017-09-272022-10-30 Journal: Journal of Virology [Category] Coronavirus, [키워드] Actin activated Activation Analysis antiviral drug approach cause Cell cells cellular entry Central nervous system China cholesterol clathrin Clathrin-mediated endocytosis CNS confocal microscopy contagious coronavirus death disease dissect dominant negative dysfunction Encephalomyelitis endocytic pathways endocytosis etiological agent Exocytosis GTPase Guidance Host infected cell Infection Invasion investigated involved knowledge mechanism molecular mechanism mutant nerve cell Neural neurological neurovirulent neurovirulent coronavirus occur overexpression Pathogenesis pathway performed pharmacological porcine hemagglutinating encephalomyelitis virus positive-sense positively correlated progression Rab required RNA coronavirus RNA interference single-stranded suggested target TEM Therapeutic strategies transfer transmission electron microscopy understanding viral endocytosis viral entry viral entry pathway virus virus particles were used [DOI] 10.1128/JVI.01083-17 PMC 바로가기 [Article Type] Virus-Cell Interactions
Multiple essential functions of Plasmodium falciparum actin-1 during malaria blood-stage development말라리아 혈액 단계 발달 중 Plasmodium falciparum actin-1의 여러 필수 기능Research Article Published on 2017-08-152024-07-27 Journal: BMC Biology [Category] 말라리아, [키워드] Actin Actomyosin apicomplexa Apicoplast Conditional gene disruption cytokinesis cytoskeleton egress Invasion malaria Merozoite Plasmodium Plasmodium falciparum [DOI] 10.1186/s12915-017-0406-2 PMC 바로가기 [Article Type] Research Article
MicroRNA-275 targets sarco/endoplasmic reticulum Ca 2+ adenosine triphosphatase (SERCA) to control key functions in the mosquito gutMicroRNA-275는 모기장에서 주요 기능을 제어하기 위해 sarco/endoplasmic reticulum Ca 2+ adenosine triphosphatase(SERCA)를 표적으로 합니다.Research Article Published on 2017-08-072022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin activating active transport addition adenosine Aede affecting approach Arboviruses assembly Blood blood meal cancers cardiac hypertrophy caused Chikungunya Combination conserved contribute contributing to correlated Critical cytosol decoy decrease Dengue deplete digestion digestive digestive enzyme enzyme female Fever fevers finding function functions Gut gut microbiota guts heart failure homeostasis human diseases humans implicated injection Injections investigated involved knowledge leads maintenance mechanism microRNA miRNA Mosquito mRNA Notch pathogen pathogen transmission Pathogens phenotype Proteases Protein protein level protein levels reduction regulate Regulation remained repeated required rescued RNA sequence SERCA shown signaling pathway significantly spatiotemporal target the mosquito tissue Transcription transgenic Transport trypsin vectors yeast yellow fever yellow fevers Zika [DOI] 10.1371/journal.pgen.1006943 PMC 바로가기 [Article Type] Research Article
MoCAP proteins regulated by MoArk1-mediated phosphorylation coordinate endocytosis and actin dynamics to govern development and virulence of Magnaporthe oryzaeMoArk1 매개 인산화에 의해 조절되는 MoCAP 단백질은 세포내이입과 액틴 역학을 조정하여 Magnaporthe oryzae의 발병 및 독성을 제어합니다Research Article Published on 2017-05-252022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Actin addition Analysis Author cellular conidia conidiation connection conserved Deletion endocytosis eukaryotic cells Evidence exhibited F-actin function functions fungi growth homolog host cells host infection hyphal in vivo invasive lead Magnaporthe mechanism modulate mutant mutants mycelial participated pathogenic pathogenicity penetration phosphatidylinositol phospholipid Phosphorylation PIP previous study Protein protein phosphorylation provided reduced regulate regulated Regulation required residue Signaling subject subunit type strain virulence wild-type strain [DOI] 10.1371/journal.pgen.1006814 PMC 바로가기 [Article Type] Research Article
Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [ PSI + ] prion formation피질의 액틴 세포골격을 교란하는 것은 효모 [PSI + ] 프리온 형성의 두 가지 뚜렷한 메커니즘을 나타냅니다.Research Article Published on 2017-04-032022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogate abrogated Actin affected Affinity purification aggregate aggregates aggregation Analysis antioxidant component composed conditions cortical Deletion disease disrupt examined form forms fragmentation Frequency fungal identify implicated increase infectious agent infectious agents insoluble protein mass spectrometry mechanism misfolded protein misfolded proteins molecular MOST mutant mutants neurodegenerative occur overexpression oxidative oxidative damage oxidative stress oxidized Prevent Previous studies previous study prion Probability Protein Protein misfolding Proteins PSI reduced required thought transition translation Trigger undergo yeast yeast cell yeast cells [DOI] 10.1371/journal.pgen.1006708 PMC 바로가기 [Article Type] Research Article