Adaptive immune response – Page 5 – Communicable Diseases Research

Effective Anti-SARS-CoV-2 Immune Response in Patients With Clonal Mast Cell Disorders

클론 비만 세포 장애 환자에서 효과적인 항 SARS-CoV-2 면역 반응

Article

Published on 2022-05-012022-09-11
Journal: The journal of allergy and clinical immunology. In [Category] COVID19(2023년), MERS, SARS, 진단, 치료제,

Underlying Co-Morbidity Reveals Unique Immune Signatures in Type II Diabetes Patients Infected With SARS-CoV2

Article

Published on 2022-04-272023-07-09
Journal: Frontiers in Immunology [Category] COVID19(2023년),

[키워드] Adaptive immune response innate immune response SARS-CoV2 Type II Diabetes whole blood immunophenotyping.
[DOI] 10.3389/fimmu.2022.848335 PMC 바로가기

Trained immunity-related vaccines: innate immune memory and heterologous protection against infections

Review article

Published on 2022-04-212022-10-05
Journal: Trends in molecular medicine [Category] 비임상,

Differences in SARS-CoV-2 Vaccine Response Dynamics Between Class-I- and Class-II-Specific T-Cell Receptors in Inflammatory Bowel Disease

염증성 장 질환에서 클래스 I 및 클래스 II 특정 T 세포 수용체 간의 SARS-CoV-2 백신 반응 역학의 차이

Article

Published on 2022-04-082022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단,

[키워드] Ad26 Ad26.COV2.S Adaptive immune response adaptive immune responses age analyzed antibody antibody levels Antigen antigens BNT162b2 booster bowel characterized clone clones Cohort conditions Critical deficiencies deficiency difference Dynamics expansion Factor HCWs Health care Health care worker health care workers IBD immune factors immune response immune responses Immune-mediated immunodeficiency immunomodulatory induce Infection Inflammatory Inflammatory bowel disease inflammatory disease Inflammatory diseases intestinal mechanism molecular mRNA mRNA vaccine mRNA-1273 vaccine Patient patients protocols response responses robust SARS-CoV-2 SARS-CoV-2 (COVID-19) SARS-CoV-2 vaccination sequenced Sequencing significant difference significant differences Spectrum stratified subset T-cell T-cell receptor T-cell repertoire T-cell Response T-cell responses T-cells TCR the patient Treatment understanding vaccination vaccination response vaccination schedule Vaccine
[DOI] 10.3389/fimmu.2022.880190 PMC 바로가기 [Article Type] Article

Ad26.COV2.S prevents upregulation of SARS-CoV-2 induced pathways of inflammation and thrombosis in hamsters and rhesus macaques

Ad26.COV2.S는 햄스터와 붉은털 원숭이에서 SARS-CoV-2 유도 염증 및 혈전증 경로의 상향 조절을 방지합니다

Article

Published on 2022-04-082022-09-11
Journal: PLoS Pathogens [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단,

[키워드] Ad26 Ad26.COV2.S Adaptive immune response Adenovirus animal models B cell B.1.351 binding comparable complement COVID-19 COVID-19 pathogenesis expressing feature golden hamsters hamster hamsters human disease immune responses immunization induce Inflammation Inflammatory molecular mechanism molecular mechanisms mRNA expression profile mRNA expression profiles myeloid Neutralizing antibody response neutralizing antibody responses Pathogenesis pathway Pathways Prevent prevented Protective proteomics recent rhesus macaque rhesus macaques SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2 WA1/2020 serotype severe COVID-19 severe disease shown Spike protein stimulate Syrian golden hamster Syrian Golden hamsters These data thrombosis transcriptional type I interferon uninfected upregulation vaccination Vaccine Vaccines weight loss with COVID-19
[DOI] 10.1371/journal.ppat.1009990 PMC 바로가기 [Article Type] Article

In-depth analysis of SARS-CoV-2-specific T cells reveals diverse differentiation hierarchies in vaccinated individuals

SARS-CoV-2-특이적 T 세포에 대한 심층 분석은 백신 접종을 받은 개인의 다양한 분화 계층을 보여줍니다

Article

Published on 2022-04-082022-09-11
Journal: JCI Insight [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] Adaptive immune response Adaptive immunity Analysis approach breadth Breakthrough infection breakthrough infections CD4+ T cell CD4+ T cells clinical trial clinical trials COVID-19 COVID-19 pandemic cytokine profile determinant effective Efficacy feature fraction Fractions identify IL-2 immune immunology indicate individual induce investigated Last Longevity magnitude majority mutant produced reactive recall Region responders reveal S-protein SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2-specific T cell SARS-CoV-2-specific T cells T cell T cell response T cells TNF-α vaccinated individual vaccinated individuals vaccination Vaccine variants of concern
[DOI] 10.1172/jci.insight.156559 PMC 바로가기 [Article Type] Article

SARS-COV-2 Infection, Vaccination, and Immune-Mediated Diseases: Results of a Single-Center Retrospective Study

Observational Study

Published on 2022-03-212022-10-04
Journal: Frontiers in Immunology [Category] SARS, 임상,

[키워드] Adaptive immune response affected alteration anti-SARS-CoV-2 antibody anti-spike antibodies antibody Arthritis Autoimmunity clinical manifestation Cohort complex conducted correlated correlation COVID-19 COVID-19 pandemic deregulated described diagnosed evaluated group healthy healthy subject healthy subjects Hospitalized Host Hypothesis immune immune response Immune-mediated immune-mediated disease Immuno-Mediated Reactions induce Infection Inpatient Laboratory manifestation myocarditis Occurrence Outpatient Patient Reactions responsible Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV2 serological Support Symptom vaccination Vaccine vaccine antigen
[DOI] 10.3389/fimmu.2022.859550 PMC 바로가기 [Article Type] Observational Study

CD8 + T Cell Senescence: Lights and Shadows in Viral Infections, Autoimmune Disorders and Cancer

CD8 + T 세포 노화: 바이러스 감염, 자가면역 장애 및 암의 빛과 그림자

Review

Published on 2022-03-212022-09-11
Journal: International Journal of Molecular Sciences [Category] Coronavirus, SARS, 바이오마커,

[키워드] Adaptive immune response addition Ageing Antigen Autoimmune Autoimmune disease Autoimmune diseases autoimmune disorder Autoimmune disorders Cancer cause caused CD28 CD28− CD57+ CD8+ T cells CD57 CD8 CD8+ Cell circulating clearance CMV condition contributing to cytotoxic function Diseases Effect Efficacy enrichment exacerbate favor function functions heterogeneous HIV immune-senescence immunological immunotherapies Immunotherapy implication IMPROVE Infection inflammaging inflammaging. life LIGHT low-grade inflammation lowering Lymphocytes memory Memory cells novel antigen novel antigens pathogen Pathogens phenotype Prevent progression reduction SARS-CoV-2 senescent shadow Stress switching T cell T cells T lymphocyte T lymphocytes the disease thymic Transformed cell transformed cells Tumor tumor microenvironment turn Vaccine vaccine efficacy Viral viral infection viral infections
[DOI] 10.3390/ijms23063374 PMC 바로가기 [Article Type] Review

Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity

Article

Published on 2022-03-172023-06-16
Journal: Cell [Category] COVID19(2023년), MERS, SARS,

[키워드] Adaptive immune response COVID-19 Human Hybrid immunity memory B cell memory T cell SARS-CoV-2 Vaccine
[DOI] 10.1016/j.cell.2022.03.018 PMC 바로가기 [Article Type] Article

Micro-Fourier-transform infrared reflectance spectroscopy as tool for probing IgG glycosylation in COVID-19 patients

COVID-19 환자에서 IgG 글리코 실화를 조사하기위한 도구로서 마이크로 푸리에 변환 적외선 반사 분광 광경.

Article

Published on 2022-03-112022-09-01
Journal: Scientific Reports [Category] MERS, SARS, 변종, 진단, 치료기술,

[키워드] Activation Adaptive immune response Anti-spike antibody Antibody Response Asymptomatic Biophotonics Blood Brazil carbonyl chemiluminescent immunoassay CLIA correlation COVID-19 COVID-19 patient COVID-19 patients Critically ill Cutoff detection rate diagnosed with COVID-19 Diagnostic markers disease dissemination ELISA excessive inflammatory response extension glycosylation healthcare worker healthy helping IgA IgG IgG antibodies IgG1 IgM immune response Immunoglobulin indicated individual individuals with COVID-19 Infection marker Mild Optics and photonics Other photonics outcome Patient patients Physiology positive probe Quantitative RBD reported SARS-CoV-2 SARS-CoV-2 viral load serum sample serum samples severity signal specificity Viral Viral antigen Volunteer worsening
[DOI] 10.1038/s41598-022-08156-6 PMC 바로가기 [Article Type] Article