Continuous development of the semantic search engine preVIEW: from COVID-19 to long COVID의미 검색 엔진 preVIEW의 지속적인 개발: COVID-19에서 긴 COVID까지Article Published on 2022-07-012022-09-11 Journal: Database: The Journal of Biological Databases and [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 added addition annotation annotations articles automatically Classifier Continuous coronavirus coronavirus disease COVID COVID-19 curated described disease False positives feature feedback include Infection MOST Occurrence participated peer-reviewed retrieved SARS-CoV-2 service severe acute respiratory syndrome Coronavirus Symptom true positive true positives Usability user variant virus [DOI] 10.1093/database/baac048 PMC 바로가기 [Article Type] Article
Immunoinformatic approach for the construction of multi-epitopes vaccine against omicron COVID-19 variant오미크론 COVID-19 변이체에 대한 다중 에피토프 백신 구축을 위한 면역정보학적 접근Article Published on 2022-07-012022-09-11 Journal: Virology [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] added adjuvant antigenic antigenic epitope antigenic epitopes applied approach B cell epitope B cell epitopes B-cell B.1.1.529 CD4 CD8 chimeric Chimeric vaccine model codon optimization complexes computational tool computational tools concern construction country COVID-19 COVID-19 omicron variant effective epitope Epitopes expression Final flexible Health Organization help highly antigenic Host IFN-γ immune mechanism immunogenic in-silico increasingly inducer initiative linker MEV MHC-II molecular molecular docking molecular dynamics mutagenic N-terminal non-allergenic non-toxic omicron Omicron variant overlapping peptide peptide-based planet Protein reverse vaccinology SARS-CoV-2 SARS-CoV-2 infections SARS-CoV-2 variant Scientific community Simulation spike Spike protein stability suggested T-cell T-cell epitopes TLR TLR2 TLR4 TLRs toxic treat unique vaccination Vaccine vaccine candidate variant VoC WHO World Health Organization [DOI] 10.1016/j.virol.2022.05.001 PMC 바로가기 [Article Type] Article
Editorial: World Health Organization (WHO) Variants of Concern Lineages Under Monitoring (VOC-LUM) in Response to the Global Spread of Lineages and Sublineages of Omicron, or B.1.1.529, SARS-CoV-2사설: Omicron 또는 B.1.1.529, SARS-CoV-2의 혈통 및 하위 혈통의 글로벌 확산에 대한 WHO(World Health Organization) 모니터링 중인 관심 혈통의 변종(VOC-LUM)Editorial Published on 2022-07-012022-09-11 Journal: Medical science monitor : international medical jo [Category] COVID19(2023년), SARS, 변종, [키워드] added B.1.1.529 concern Control dominant ECDC editorial Europe European FIVE global public health Health Organization include Infection Lineage lineages monitoring neutralization omicron Omicron variant Patient plasma prevention Prevention and control response SARS-CoV-2 SARS-CoV-2 variant shown Spread tested the WHO Transmissibility USA variant variant of SARS-CoV-2 variants variants of concern variants of interest VoC WHO World Health Organization [DOI] 10.12659/MSM.937676 PMC 바로가기 [Article Type] Editorial
Evaluation of commercial Anti-SARS-CoV-2 neutralizing antibody assays in seropositive subjects혈청 양성 환자에서 상업용 Anti-SARS-CoV-2 중화 항체 분석 평가Article Published on 2022-07-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] absence added addition anti-RBD Anti-RBD antibodies Anti-RBD antibody anti-spike antibody anti-Spike IgG antibody Antibody titer Area bioMérieux cells cellular receptor Commercial tests Competitive anti-RBD immunoassays correlation difficulty functional highlight house immunoassay immunoassays immunochromatographic test Interaction marker NAb titer NAb titers neutralization test Neutralizing antibodies neutralizing antibody neutralizing antibody assay New P-value patients plaque reduction neutralization PRNT qualitative test Quantitative reduction SARS-CoV-2 SARS-CoV-2 entry Sensitivity and specificity sera seropositive subject seropositive subjects Spike protein surrogate surrogate markers Surrogate markers of protection. sVNT tested the spike protein threshold thresholds titer variants of concern virus neutralization test VNT VoC [DOI] 10.1016/j.jcv.2022.105169 PMC 바로가기 [Article Type] Article
One Swab Fits All: Performance of a Rapid, Antigen-Based SARS-CoV-2 Test Using a Nasal Swab, Nasopharyngeal Swab for Nasal Collection, and RT-PCR Confirmation from Residual Extraction Buffer모든 면봉에 적합: 비강 면봉, 비강 수집용 비인두 면봉 및 잔류 추출 완충액에서 RT-PCR 확인을 사용한 신속한 항원 기반 SARS-CoV-2 테스트 수행Article Published on 2022-06-302022-09-11 Journal: The journal of applied laboratory medicine [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI 95% confidence interval Accuracy added Antigen antigen tests Care care provider collected Collection Community confidence interval confirmation COVID-19 COVID-19 pandemic detect determine diagnosed with COVID-19 diagnostics Effectiveness extraction extraction buffer Health Health care help individual Laboratory nasal Nasal sample nasal samples nasal swab nasal swabs Nasopharyngeal swab nasopharyngeal swabs performance POCT point-of-care positive presenting Rapid rapid diagnostics recruited residual reverse-transcriptase PCR RT-PCR SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 test SARS-CoV-2 testing sensitivities Swab symptom onset symptomatic adult symptomatic adults Test tested throat swab Transport media variants variants of concern were used [DOI] 10.1093/jalm/jfac004 PMC 바로가기 [Article Type] Article
Virucidal Properties of Photocatalytic Coating on Glass against a Model Human Coronavirus모델 인간 코로나바이러스에 대한 유리의 광촉매 코팅의 바이러스 살균 특성Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료제, [키워드] added aerosol alteration Antiviral antiviral activity can not coated with coating construction Contact Contagion Contamination coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 damaged deformation Disruption electron microscopy element Epidemiology Evidence evidence of exposure to glass human coronavirus human coronaviruses in-depth analysis inactivation increase infectious investigated Kinetics knowledge Masks Microscopy mitigate Model morphologically pandemic performed Photocatalysis photocatalytic coating physical physical barrier property Protective protective effect Protective effects reduced reducing Research SARS-CoV-2 Spread suggested surface titanium titanium dioxide Transmission viral envelope virion virions virucidal virucidal activity virus virus spread virus titer viruses [DOI] 10.1128/spectrum.00269-22 PMC 바로가기 [Article Type] Article
A modified vaccinia Ankara vaccine expressing spike and nucleocapsid protects rhesus macaques against SARS-CoV-2 Delta infection스파이크와 뉴클레오캡시드를 발현하는 변형된 백시니아 앙카라 백신은 SARS-CoV-2 Delta 감염으로부터 붉은털 원숭이를 보호합니다Article Published on 2022-06-242022-09-11 Journal: Science Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] added Beta Beta variant binding Blood CD4 CD8 T cell correlated cross-reactive cross-reactive antibody Delta delta variant Efficacy elicited expressed expressing FCS function furin furin cleavage site Heterologous homologous human ACE2 humoral IgG inactivated inactivation induce Infection intramuscular less lung mice moderate neutralized Neutralizing Neutralizing antibodies neutralizing antibody non-neutralizing antibody nose nucleocapsid positively correlated PROTECT rectum response rhesus macaque rhesus macaques robust SARS-CoV-2 SARS-CoV-2 vaccines secretion serum spike spike-specific IgG T cell T cell response T cell responses tested the SARS-CoV-2 vaccination Vaccine variant variants of concern virus VoC VOCs [DOI] 10.1126/sciimmunol.abo0226 PMC 바로가기 [Article Type] Article
Silent Antibodies Start Talking: Enhanced Lateral Flow Serodiagnosis with Two-Stage Incorporation of Labels into Immune ComplexesSilent Antibodies Start Talking: 면역 복합체에 라벨을 2단계 통합하여 향상된 측면 흐름 혈청 진단Article Published on 2022-06-212022-09-11 Journal: Biosensors [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] added antibody Antigen applied approach binding Blood carried coloration complexes conjugate coronavirus COVID-19 demonstrated diagnostic diagnostic sensitivity diagnostic specificity enhanced false-negative false-negative results first stage Flow gold Gold nanoparticle Immune complexes immunochromatographic immunochromatography Immunoglobulin immunoglobulins incorporation increase in intensity lAbel Lateral lateral flow immunoassay LFIA magnitude membrane non-specific pathogen pathogen-specific Protein protein A RBD RBD protein recombinant RBD protein reduction risk SARS-CoV-2 separated serodiagnostic specific antibodies specificity staphylococcal test strip test strips. The diagnostic sensitivity variant zone [DOI] 10.3390/bios12070434 PMC 바로가기 [Article Type] Article
High throughput SARS-CoV-2 variant analysis using molecular barcodes coupled with next generation sequencing차세대 시퀀싱과 결합된 분자 바코드를 사용하여 처리량이 높은 SARS-CoV-2 변이체 분석Article Published on 2022-06-212022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] added amplifying Analysis benefit diagnostic Diagnostic method DNA epidemiological followed by globe housekeeping gene identify Illumina implication Infection Internal control Modification molecular next generation sequencing NGS nucleotide pandemic pooling positive positive sample primer Primers purified RT-PCR SARS-CoV-2 variant SARS-CoV-2 variants Screen sensitivity sequence Sequencing single nucleotide specificity vaccination variant Viral viral gene viral genes viral mutation Viral mutations virus [DOI] 10.1371/journal.pone.0253404 PMC 바로가기 [Article Type] Article
Clinical Severity of SARS-CoV-2 Omicron Variant Compared with Delta among Hospitalized COVID-19 Patients in Belgium during Autumn and Winter Season 2021-20222021-2022년 가을 및 겨울 시즌 동안 벨기에의 입원한 COVID-19 환자 중 델타와 비교한 SARS-CoV-2 오미크론 변이의 임상 심각도Multicenter Study Published on 2022-06-142022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI added adjusted Admission Analysis Belgium clinical cohort study Combination Comorbidities confounder COVID-19 COVID-19 pathogenesis COVID-19 patient Delta delta variant demographics genomic genomic data Genomic surveillance hospital Hospital mortality hospitalized patient hospitalized patients ICU ICU admission in-hospital mortality intensive care intensive care unit multifactorial multivariable logistic regression Multivariable logistic regression analysis National not significantly different omicron Omicron variant recognize retrospective risk SARS-CoV-2 SARS-CoV-2 variant season severe COVID-19 severity significantly lower study population Surveillance the SARS-CoV-2 vaccination Vaccination Status variant were infected Winter [DOI] 10.3390/v14061297 PMC 바로가기 [Article Type] Multicenter Study