Model-based cost-effectiveness analysis of oral antivirals against SARS-CoV-2 in Korea국내 SARS-CoV-2에 대한 경구용 항바이러스제의 모델 기반 비용 효율성 분석Article Published on 2022-01-012022-09-11 Journal: Epidemiology and Health [Category] SARS, 치료제, [키워드] Admission Adult patients Adults Analysis Antiviral antiviral agent Antiviral agents calculated Care coronavirus disease Coronavirus disease 2019 Cost-effectiveness analysis country COVID-19 COVID-19 patient Efficacy Elderly patient elderly patients Emergency use group health system Hospital admission Hospitalization ICU less medical system Mild-to-moderate molnupiravir Nirmatrelvir Patient patients predicted reduce reducing Ritonavir SARS-CoV-2 Severe case severe COVID-19 Severe patient standard care symptomatic Treatment underlying disease underlying diseases [DOI] 10.4178/epih.e2022034 PMC 바로가기 [Article Type] Article
Innate and Adaptive Immunity Imbalance With Severe COVID-19 Pneumonia in Children and AdultsPediatrics Published on 2021-12-152022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] Abnormalities adaptive adaptive immune cells Admission Adult patient Adult patients Adults alteration analyzed CD14+ monocyte CD3+ CD4+ T cell CD8+ T cell Characteristics Chest CT children clinical complication clinical manifestation Clinical symptoms Comorbidities Control controls coronavirus disease COVID-19 COVID-19 patient COVID-19 patients Critical enrolled Frequency had more healthy Imbalance immune Immune cell immune response alteration Inflammatory response Innate Innate immune cells Laboratory laboratory abnormalities Laboratory features lymphocyte Mild much higher Patient patients pilot study Pneumonia Prevalence radiological real-time RT-PCR recruited SARS-CoV-2 severe patients significantly lower subpopulations subset survived T-lymphocyte with COVID-19 [DOI] 10.3389/fped.2021.736013 PMC 바로가기 [Article Type] Pediatrics
Prevalence, classification, risk factors and outcome impact of delirium in patients with COVID-19: a meta-analysis protocol for systematic reviewCOVID-19 환자에서 섬망의 유병률, 분류, 위험 요인 및 결과 영향 : 체계적인 검토를위한 메타 분석 프로토콜Article Published on 2021-12-132022-08-31 Journal: BMJ Open [Category] meta-analysis, SARS, [키워드] adult intensive & Adult patients all-cause mortality Analysis association Beijing bioRxiv Characteristics classification Clinical outcome cognitive cognitive disorders. cohort study concerning conducted COVID-19 Critical Critical care database databases delirium delirium & disorders essential element estimate Ethical approval Ethics ethics committee evaluate Evidence evidence of high risk hospitalisation identify inception include institutional review board Intensive ISI medRxiv Meta-analysis meta-regression multivariable outcome Patient patients with COVID-19 peer-reviewed performed Prevalence Previous studies previous study primary and secondary outcomes Primary outcome PROSPERO protocol registration number risk factor Risk factors robustness secondary outcome Secondary outcomes Sensitivity analyses shown Study design Subgroup analyses systematic review Web of Science were used [DOI] 10.1136/bmjopen-2020-048323 PMC 바로가기 [Article Type] Article
Real world utilization of REGEN-COV2 at a community hospital지역 병원에서 REGEN-COV2의 실제 활용Article Published on 2021-12-012022-09-11 Journal: The American journal of emergency medicine [Category] 진단, 치료제, [키워드] Adult patients age allergic reaction Allergic reactions antibody authorization Casirivimab Community community hospital coronavirus disease Coronavirus disease 2019 COVID-19 decrease demographics determine drug Drug administration Emergency emergency department Emergency use authorization EUA female food greater healthcare hospital Hospital mortality Hospitalization hospitalizations Hospitalized Imdevimab in-hospital mortality infused infusion IQR median median age median time Mild mild to moderate Mild to moderate COVID-19 moderate Moderate COVID-19 monoclonal antibodies monoclonal antibody Patient REGN-CoV2 Seven shown study period suffered the median treated Treatment Viral Viral load were given [DOI] 10.1016/j.ajem.2021.07.050 PMC 바로가기 [Article Type] Article
Fighting the pandemic with collaboration at heart: Report from cardiologists in a COVID-19-dedicated Portuguese intensive care unit협력을 중심으로 전염병 퇴치: COVID-19 전담 포르투갈 집중 치료실의 심장 전문의의 보고서Article Published on 2021-12-012022-09-11 Journal: Revista portuguesa de cardiologia [Category] SARS, 치료기술, [키워드] Adult patients age analyzed cardiac marker Cardiac markers Cardiologia Cardiology cardiovascular risk Care changed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 prognosis Cuidados intensivos Cuidados multidisciplinares de novo Decision making died discharged dysfunction dyslipidemia English Extra-corporeal membrane oxygenation Fighting followed by hypertension ICU intensive care male Manifestations mechanical ventilation membrane mobilization Multidisciplinary care myocardial injury N-terminal N-terminal pro-B-type natriuretic peptide Nova NT-proBNP one patient Oxigenação por membrana extracorporal pandemic Patient Patient care patients with COVID-19 pelo peptide pro-B-type natriuretic peptide report required Respiratory illness severe COVID-19 Spread Takotsubo the disease Vasopressor vasopressor support [DOI] 10.1016/j.repce.2021.11.009 PMC 바로가기 [Article Type] Article
Impact of early versus late administration of bamlanivimab on readmissions in patients with high-risk COVID-19고위험 COVID-19 환자의 재입원에 대한 밤라니비맙의 조기 투여와 후기 투여의 영향Observational Study Published on 2021-12-012022-09-11 Journal: The American journal of emergency medicine [Category] MERS, 임상, 진단, 치료제, [키워드] Administered administration Adult patients Analysis bamlanivimab benefit characteristics of patient clinical decompensation Clinical outcome clinical outcomes COVID-19 COVID-19 positive patient COVID-19 positive patients criteria decompensation determine dichotomized emergency department Emergency use authorization EUA expand Future group High-risk COVID-19 hospital Hospitalization ICU Impact in-hospital mortality intensive care intensive care unit less LOS monoclonal antibody monoclonal antibody therapies monoclonal antibody therapy Monoclonal antibody therapy. no difference no differences outcome Patient Primary outcome Prospective Study readmission recombinant retrospective secondary Secondary outcomes Symptom symptom onset the timing therapy Treatment treatment failure two groups [DOI] 10.1016/j.ajem.2021.08.032 PMC 바로가기 [Article Type] Observational Study
Usefulness of Right Ventricular Longitudinal Shortening Fraction to Detect Right Ventricular Dysfunction in Acute Cor Pulmonale Related to COVID-19COVID-19와 관련된 급성 폐동맥류에서 우심실 기능 부전을 감지하기 위한 우심실 종축 단축 분획의 유용성Article Published on 2021-12-012022-09-11 Journal: Journal of cardiothoracic and vascular anesthesia [Category] SARS, 치료기술, [키워드] 24 hours acute cor pulmonale acute respiratory distress acute respiratory distress syndrome Adult patient Adult patients ARDS ARDS (Acute Respiratory Distress Syndrome) Care classic consecutive patient contrary cor Cor Pulmonale coronavirus disease Coronavirus disease 2019 correlation COVID-19 cut-off value defined detect diagnosed dysfunction echocardiographic parameter echocardiographic parameters fraction France identify intensive care unit longitudinal measurement mechanical ventilation no significant difference not altered parameter parameters Patient Prospective respiratory distress right right ventricle right ventricle dysfunction sensitivity shortening specificity speckle tracking strain syndrome TAPSE tricuspid tricuspid. university ventricular were measured [DOI] 10.1053/j.jvca.2021.01.025 PMC 바로가기 [Article Type] Article
Effect of Chloroquine and Hydroxychloroquine on Cytokine Release Syndrome in Patients with COVID-19COVID-19 환자의 사이토카인 방출 증후군에 대한 클로로퀸 및 하이드록시클로로퀸의 효과Randomized Controlled Trial Published on 2021-12-012022-09-11 Journal: Clinical medicine & research [Category] SARS, 임상, 치료기술, 치료제, [키워드] Adult patients age blinded Care Chain Reaction Chloroquine conducted coronavirus disease Coronavirus disease 2019 COVID-19 CRS Cytokine release syndrome Department diagnose diagnoses Effect electrochemiluminescence immunoassay Emirate enrolled hospitalized patient Hydroxychloroquine IL-6 interleukin interleukin 6 Medicine Mild mild to moderate mild to moderate symptoms moderate no effect no significant difference onset of symptom Patient patients patients with COVID-19 placebo-controlled polymerase chain polymerase chain reaction randomization randomized study reducing Release Result reverse transcription reverse transcription polymerase chain reaction Roche RT-PCR screened serum sample serum samples significant difference study groups Symptoms the mean the patient three groups Treatment with COVID-19 [DOI] 10.3121/cmr.2021.1659 PMC 바로가기 [Article Type] Randomized Controlled Trial
Clinical and virological impact of single and dual infections with influenza A (H1N1) and SARS-CoV-2 in adult inpatients성인 입원 환자에서 인플루엔자 A (H1N1) 및 SARS-COV-2에 대한 단일 및 이중 감염의 임상 및 바이러스 학적 영향Research Article Published on 2021-11-292022-09-10 Journal: PLoS Neglected Tropical Diseases [Category] MERS, SARS, 신종인플루엔자, 유전자 메커니즘, 진단, 치료기술, [키워드] Acute heart failure Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus Admission admittance Adult patients adults hospitalized adverse event adverse events affected All participant All participants All the patient all the patients ARDS Bacterial infections baseline both virus both viruses caused China clinical Clinical outcome Clinical severity clinical status Clinical symptoms Co-infection Coinfection Comprehensive coronavirus COVID-19 pandemic Ct value Ct values demographic described diagnosis of COVID-19 diagnostics electronic medical record electronic medical records enrolled Epidemic Frequency future therapeutic groups Guangdong Guangzhou H1N1 H1N1 infection heart failure Hospitalization Hospitalized ICU incidence Infection Influenza influenza A initial Inpatient Inpatients laboratory data Lower mechanism median medical records molecular nasopharyngeal swabs Older age Ordinal Scale Patient patients patients hospitalized PCR cycle positively correlated Prevalence prevalence rate Prophylactic respiratory SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection score Seasonal influenza Secondary bacterial infections seven-category ordinal scale severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease significantly Symptom tested threshold trajectory Transmission Treatment Viral Viral load Viral RNA viral RNA detection Virological virus viruses were assessed with COVID-19 [DOI] 10.1371/journal.pntd.0009997 PMC 바로가기 [Article Type] Research Article
Janus kinase inhibitors and major COVID-19 outcomes: time to forget the two faces of Janus! A meta-analysis of randomized controlled trials야누스 키나제 억제제와 코로나19 주요 결과: 야누스의 두 얼굴을 잊어야 할 때! 무작위 대조 시험의 메타 분석Meta-Analysis Published on 2021-11-012022-09-11 Journal: Clinical Rheumatology [Category] SARS, 임상, [키워드] added Adult patients antibody production assigned Baricitinib benefit concerning coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 infection Cytokine storm database death disease ECMO Efficacy Endpoint ENhance evaluate extracorporeal membrane oxygenation global public health In-hospital Inflammatory response inhibitor Jak JAK inhibitor jak inhibitors janus Janus kinase Janus kinase inhibitor Kinase inhibitor Mechanical mechanical ventilation mechanism Meta-analysis Mortality nezulcitinib nightmare outcome outcomes pathophysiologic Patient patients with COVID-19 Randomized controlled trial Randomized controlled trials RCT RCTs reduction in risk risk reduction ruxolitinib searched significant decrease stages Standard of care subject Tofacitinib Treatment [DOI] 10.1007/s10067-021-05884-4 PMC 바로가기 [Article Type] Meta-Analysis