Numbers of close contacts of individuals infected with SARS-CoV-2 and their association with government intervention strategiesResearch Published on 2021-12-092022-10-28 Journal: BMC Public Health [Category] Coronavirus, SARS, [키워드] “contact tracing” “COVID-19” “interventions” “SARS-CoV-2” age analysed Analysis association associations assumption average binomial regression model breakpoint changes in close contact Cohort conducted confirmed case Contact Contact tracing decrease demographics epidemiological evaluate expected Government greater increases in indicated individual infected with SARS-CoV-2 information Intervention Ireland negative number provide reduction in Regression model reported Result secondary Separate supplementary material the mean Transmission [DOI] 10.1186/s12889-021-12318-y PMC 바로가기 [Article Type] Research
Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study멘델식 무작위 배정 연구에서 지질 저하 약물과 COVID-19 결과의 연관성Research Article Published on 2021-12-062022-09-10 Journal: eLife [Category] 변종, 신약개발, 치료제, [키워드] 95% CI 95% confidence interval Analysis approach association associations benefit Blood calculate carried causal relationship caused cholesterol clinical trial confounding bias COVID-19 COVID-19 hospitalization COVID-19 pandemic death decrease drug drugs eLife estimates Evidence expression expression quantitative trait loci faster fat funding genetic instrument genetic instruments Genetic variant genetic variants Genome-wide association study higher risk HMGCR Hospitalization Hospitalized Human Hypothesis identify in viral infected with SARS-CoV-2 Infection infections LDL cholesterol Lipid lipid metabolism lipid-lowering drugs loci low-density Low-density lipoprotein mendelian randomization Mendelian randomization studies Mendelian randomization study metabolism Mortality MR study NPC1L1 Odds ratio outcome Patient PCSK9 positive protective effect Quantitative reduce reduced risk SARS-CoV-2 SARS-COV-2 infection severe disease SMR statins suggested susceptibility target gene Target genes treating COVID-19 university variable Viral viral infections virus were used with COVID-19 [DOI] 10.7554/eLife.73873 PMC 바로가기 [Article Type] Research Article
Obstetrical outcomes and maternal morbidities associated with COVID-19 in pregnant women in France: A national retrospective cohort study프랑스 임산부의 Covid-19와 관련된 산과 적 결과 및 모체 이환율 : 국가 후 향적 코호트 연구Research Article Published on 2021-11-302022-09-10 Journal: PLoS Medicine [Category] MERS, SARS, 진단, 치료기술, [키워드] active smoking acute respiratory syndrome coronavirus adjusted Admission adverse outcome analyzed appear ART association associations Asymptomatic best Birth body mass body mass index can not Care Causality Cesarean section Characteristics Childbirth classification Clinical practice Cohort collected data complications conception conducted controls coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 disease COVID-19 group COVID-19 pandemic database diabete diabetes Diagnosis diagnosis of COVID-19 disease distress eclampsia evaluate evaluated event favor fetal fetal distress First wave France French Frequency gestation Gestational diabetes gestational hypertension greater groups health authorities hemorrhage Hospitalization Hospitalized hypertension ICD-10 ICU increased risk Infection intensive care intensive care unit investigated knowledge less limitation Maternal maternal age morbidity Mortality multiple pregnancy multivariable logistic regression multivariable logistic regression model National Non-COVID-19 non-COVID-19 group not different not increased not significantly different obesity Obstetric offered Older Older age outcome outcomes pandemic parity Patient Placenta placenta praevia Population populations postpartum hemorrhage preeclampsia pregnancies Pregnancy pregnant pregnant women Preterm birth primiparity PROTECT raise Rate recommendation recorded reproductive researcher respiratory Result Retrospective analysis retrospective cohort study Retrospective study risk Risk factors SARS-CoV-2 second trimester severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 smoking Spread statistical analysis System thromboembolic Treatment vaccination venous thromboembolic with COVID-19 women [DOI] 10.1371/journal.pmed.1003857 PMC 바로가기 [Article Type] Research Article
Social deprivation as a risk factor for COVID-19 mortality among women and men in the UK Biobank: nature of risk and context suggests that social interventions are essential to mitigate the effects of future pandemicsOriginal Research Published on 2021-11-272022-10-29 Journal: Journal of epidemiology and community health [Category] Coronavirus, MERS, SARS, [키워드] 95% CI Adjustment age alleviate association associations baseline cardiovascular disease cause continuous scale COVD-19 COVID-19 COVID-19 mortality death Deprivation died Effect Effects Evidence Factor fatal influenza greater incidence Infection Intervention lack magnitude men mitigate Mortality National objective other diseases outcome measure Pandemics participant person years Pneumonia Prospective quantified Result resulting risk risk factor score setting Sex difference social class social deprivation UK biobank women [DOI] 10.1136/jech-2020-215810 PMC 바로가기 [Article Type] Original Research
Use and misuse of biomarkers and the role of D-dimer and C-reactive protein in the management of COVID-19: A post-hoc analysis of a prospective cohort study바이오 마커의 사용 및 오용 및 COVID-19의 관리에서 D- 차이 및 C- 반응성 단백질의 역할 : 전향 적 코호트 연구의 사후 분석Original Article Published on 2021-11-242022-08-31 Journal: Clinics [Category] MERS, SARS, 바이오마커, [키워드] acute respiratory syndrome adjusted Admission age Analysis assessment association associations Biomarker Biomarkers C-reactive protein C-reactive protein (CRP Cohort studies Comorbidities Complication coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRP CRP level CRP levels D-dimer D-dimer level death demonstrated electronic patient record Electronic patient records elevated evaluate failure FEU fibrinogen Health Care Costs high mortality hospital hospital cost Hospital mortality hospitalized patient hospitalized patients incidence indication Infection Inflammatory Inpatient Inpatients Laboratory lead logistic regression model management Mortality number of comorbidities Occurrence Odds ratio patient records post-hoc analysis predicted Prognosis prospective cohort study respiratory sequential organ failure assessment score severe acute respiratory syndrome Coronavirus Sex statistically significant systemic inflammatory thrombotic Trigger Venous Thromboembolism VTE were used with COVID-19 [DOI] 10.6061/clinics/2021/e3547 PMC 바로가기 [Article Type] Original Article
Determinants for Acceptance of COVID-19 Vaccine in NigeriaPreventive Medicine Published on 2021-11-222022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acceptance Adults affected age approval approved associations Community conducted coronavirus disease country COVID-19 COVID-19 symptom COVID-19 vaccine cross-sectional determinant determinants Efficacy and safety Epidemic FDA females Gender geographical location Google Map groups Health hospital include knowledge knowledge score majority male Malik material Nigeria nine organization over pandemic participant percentage Pfizer Public questionnaire random recruited regions response Risk perception School Schools Statistical power statistical significance statistically significant supported the mean the United State the vaccine vaccinated against COVID-19 Vaccine vaccine candidate Vaccine hesitancy Vaccines variable virus Yale University [DOI] 10.7759/cureus.19801 PMC 바로가기 [Article Type] Preventive Medicine
Human immune diversity: from evolution to modernity Reviews Published on 2021-11-182022-10-05 Journal: Nature Immunology [Category] 변종, 유전자 메커니즘, [키워드] age allele Analysis associations Defense Denisovan develop disease environmental exposure Evolution explain extreme genetic diversity Human Human immune system identify immune Interaction loci maintain mechanism Microbiome Migration Neanderthal Pathogens pathway plethora provide Sex variable Variation [DOI] 10.1038/s41590-021-01058-1 [Article Type] Reviews
Ace2 and Tmprss2 Expressions Are Regulated by Dhx32 and Influence the Gastrointestinal Symptoms Caused by SARS-CoV-2Article Published on 2021-11-162022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] ACE2 receptor Analysis approach associations BXD mice cellular entry chromosome 7 co-expression Control coronavirus disease covariation COVID-19 COVID-19 disease demonstrated expressed expression Gastrointestinal gastrointestinal tract Genetic genetics GI tissue implication indicated influence Interaction locus microbiota molecular molecular mechanism mRNA expression network analysis pathogenesis of COVID-19 pathway priming Protein quantified Quantitative SARS-CoV-2 SARS-COV-2 infection significantly Strains suggested systems genetics the spike protein the timing TMPRSS2 traits transcript Transcriptome Treatment [DOI] 10.3390/jpm11111212 PMC 바로가기 [Article Type] Article
Intrathecal inflammatory responses in the absence of SARS-CoV-2 nucleic acid in the CSF of COVID-19 hospitalized patientsCOVID-19 입원 환자의 뇌척수액에서 SARS-CoV-2 핵산이 없을 때 척수강내 염증 반응Article Published on 2021-11-152022-09-11 Journal: Journal of the neurological sciences [Category] SARS, 변종, 치료기술, [키워드] absence acute COVID-19 albumin associations Atypical Blood Blood brain barrier cell count cerebrospinal fluid chemokine chemokines consecutive patient Control correlated COVID-19 COVID-19 patient COVID-19 patients Cryptococcus neoformans CSF Cytokines detectable evidence of healthy control HIV HIV-1 hospitalized patient IL-15 IL-6 IL-8 Infection Inflammation Inflammatory cytokine Inflammatory cytokines Inflammatory response inhibitory Intrathecal marker MCP-1 metagenomic sequencing MIP-1β monocyte Neurological symptom Neurological symptoms NEUROLOGY neurotropic pathogen Pathogens Patient patients patients with COVID-19 performed pleocytosis profile proinflammatory Proinflammatory cytokine proinflammatory cytokines Protein Quantitative reverse transcription PCR RT-qPCR SARS-CoV-2 nucleic acid SARS-CoV-2 RNA Sequencing subset suppressed two patients was tested were infected West Nile Virus White blood cell with COVID-19 [DOI] 10.1016/j.jns.2021.120023 PMC 바로가기 [Article Type] Article
Fear, anxiety and depression among pregnant women during COVID-19 pandemic: impacts of healthy eating behaviour and health literacyResearch Article Published on 2021-11-112022-10-28 Journal: Annals of Medicine [Category] COVID-19, SARS, [키워드] 95% confidence interval 95%CI addressed age analysed Analysis Antenatal Anxiety approach associations conducted COVID-19 COVID-19 crisis COVID-19 pandemic Critical cross-sectional Depression disorder elevated Factor Factors fear Health health literacy Health-related behaviours healthy healthy eating behaviour hospital Impact IMPROVE Improving influence likelihood Mental disorder mental health problem Odds ratio Other pandemic physical activity positive predictor pregnant women prenatal psychological health questionnaire Regression reproductive Result smoking the patient women [DOI] 10.1080/07853890.2021.2001044 PMC 바로가기 [Article Type] Research Article