Large-Scale Structure-Based Screening of Potential T Cell Cross-Reactivities Involving Peptide-Targets From BCG Vaccine and SARS-CoV-2BCG 백신 및 SARS-CoV-2의 펩티드 표적과 관련된 잠재적 T 세포 교차 반응성의 대규모 구조 기반 스크리닝Immunology Published on 2022-01-132022-09-11 Journal: Frontiers in Immunology [Category] 변종, [키워드] acute respiratory syndrome coronavirus Affect arising Bacillus Bacillus Calmette-Guérin BCG BCG vaccination bcg vaccine can be used caused clinical trials computational method conducted coronavirus coronavirus 2 Coronaviruses country Coverage COVID-19 cases COVID-19 pandemic cross-reactive cross-reactivity dataset death driving Evidence expand Heterologous high-density highlight HLA human leukocyte antigen Human Leukocyte Antigens identify Immunity immunogenic in silico in some infected cells involved Involving leukocyte list Lymphocytes other coronaviruses pandemic peptide peptides Potential produced provided recognize reduced reservoir respiratory responsible risk SARS-CoV-2 screened Screening severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity of COVID-19 Spread structural bioinformatics Structure structure-based screening suggested T cell target targets therapeutic strategy vaccination Vaccine Vaccine development variant variants Viral [DOI] 10.3389/fimmu.2021.812176 PMC 바로가기 [Article Type] Immunology
Heterologous vaccination interventions to reduce pandemic morbidity and mortality: Modeling the US winter 2020 COVID-19 wave전염병 이환율 및 사망률을 줄이기 위한 이종 백신 개입: 2020년 미국 겨울 COVID-19 물결 모델링422 Published on 2022-01-112022-09-10 Journal: Proceedings of the National Academy of Sciences of [Category] 변종, [키워드] age Bacillus BCG benefit Cohort Control country COVID-19 COVID-19 cases COVID-19 disease COVID-19 pandemic cross-protective dependent on determine Drug administration Effect effective Effectiveness Effects Evidence example growth Guidance Health help Heterologous heterologous vaccine Hospitalization immune immunization immunological implementation inactivated incidence Infection infections infectious disease modeling Influenza influenza vaccine Intervention malaria mathematical mathematical model modeling modulate morbidity morbidity and mortality Mortality nonpharmaceutical intervention Nonpharmaceutical interventions nonspecific pandemic Pandemics parameter Pathogens polio Polio vaccine Population reduce reduced reduction in Reproduction number Resilience SARS-COV-2 infection shown Significance stimulate the United State The United States trained immunity transmissible variant transmissible variants United States vaccinated individuals vaccination Vaccine Vaccines variants Viral [DOI] 10.1073/pnas.2025448119 PMC 바로가기 [Article Type] 422
The Association of Previous Vaccination with Live-Attenuated Varicella Zoster Vaccine and COVID-19 Positivity: An Israeli Population-Based StudyArticle Published on 2022-01-042022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI adjusted age analyses Analysis association Bacillus BCG chronic disorders Comorbidities conducted Control COVID-19 COVID-19 infection cross-sectional database demonstrated Gender independent individual Infection innate immune system likelihood live-attenuated zoster vaccine Logistic regression Logistic regression analysis matching medication multivariate Patient positive priming PROTECT retrospective risk RT-PCR RT-PCR testing selected service Sex smoking status subject tested vaccination Vaccine were used with COVID-19 Zoster [DOI] 10.3390/vaccines10010074 PMC 바로가기 [Article Type] Article
Reactivation of BCG vaccination scars after vaccination with mRNA-Covid-vaccines: two case reportsRandomized Controlled Trial Published on 2021-12-202022-10-04 Journal: BMC Infectious Diseases [Category] SARS, 임상, [키워드] 1:1 BCG BCG scar BCG vaccination Case report caused characteristic childhood children COVID-19 cross-reaction cross-reactivity described disease disease entity dose enrolled female HCW Health care worker Inclusion Influenza itching Moderna mRNA mRNA Covid-19 vaccination mRNA vaccination mRNA vaccine Neonatal offered Older participant Pathogenesis Pfizer-BioNTech provide provided Randomized randomized trial Randomly Reactivation receiving reported risk SARS-CoV-2 scar second dose secretion Symptom Treatment Trial trial participant vaccination Vaccine viral infection women [DOI] 10.1186/s12879-021-06949-0 PMC 바로가기 [Article Type] Randomized Controlled Trial
Decline in Uptake of Childhood Vaccinations in a Tertiary Hospital in Northern Ghana during the COVID-19 PandemicResearch Article Published on 2021-12-142022-10-27 Journal: BioMed Research International [Category] COVID-19, [키워드] Analysis antenatal care approach BCG Child welfare childhood children clinic conducted COVID-19 COVID-19 infection COVID-19 pandemic curative curtail Decline defined Diseases Factor fear FIVE frequencies Healthcare provider immunization Measle Microsoft Excel MR1 negatively affected outbreak pandemic pandemic era percentages Perspective Quantitative reduction in Regular rubella Study design Tamale Teaching Tertiary the vaccine uptake vaccination Vaccine was done was used [DOI] 10.1155/2021/6995096 PMC 바로가기 [Article Type] Research Article
BCG-induced immunity profiles in household contacts of leprosy patients differentiate between protection and diseaseBCG 유도 면역 프로필이 나병 환자의 가정 접촉자에서 보호와 질병을 구분합니다.Article Published on 2021-12-082024-08-24 Journal: Vaccine [Category] 한센병, [키워드] BCG Cytokines leprosy Post exposure prophylaxis trained immunity vaccination [DOI] 10.1016/j.vaccine.2021.10.027
Meeting report: Virtual Global Forum on Tuberculosis Vaccines, 20-22 April 2021회의 보고서: 결핵 백신에 관한 가상 글로벌 포럼, 2021년 4월 20-22일Article Published on 2021-12-082022-09-12 Journal: Vaccine [Category] SARS, 진단, [키워드] approach BCG COVID-19 COVID-19 pandemic develop Forum funding meeting pandemic Pipeline Prevent provided Research research findings researchers Tuberculosis Vaccine [DOI] 10.1016/j.vaccine.2021.08.094 PMC 바로가기 [Article Type] Article
A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infectionArticle Published on 2021-11-302022-10-04 Journal: NPJ Vaccines [Category] 치료기술, [키워드] abrogated addition antibody B.1.1.7 B.1.351 BCG Blood Cell circulating correlated COVID-19 COVID-19 vaccine cytokine release detectable disease effective Experimental models of disease follicular heterologous vaccine Immunity immunostimulatory Inflammation K18-hACE2 mice Local lung Lymph node mice NAbs plasma B cell promoted PROTECT protective immunity Protein vaccines provide regimen responses SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralising antibody SARS-CoV-2 spike antigen SARS-CoV-2 variant SARS-CoV-2 variants single dose T cells trimeric tuberculosis vaccine vaccination Vaccine virus Virus-specific IgG [DOI] 10.1038/s41541-021-00406-4 PMC 바로가기 [Article Type] Article
Impact of Latent Tuberculosis on Severity and Outcomes in Admitted COVID-19 PatientsInternal Medicine Published on 2021-11-252022-10-31 Journal: Cureus [Category] COVID-19, [키워드] Administered age Alanine analyzed assays BCG C-reactive protein childhood Clinical course Clinical features collected data concerning coronavirus disease COVID-19 COVID-19 patient COVID-19 severity Covid-19 subgroup diagnosed disease evaluated FIVE immunization Impact infancy interferon Laboratory parameters Latent latent tuberculosis latent tuberculosis infection LTBI lymphocyte majority mantoux test Mild monocyte National neutrophil count observation outcome Patient patients Prevalence Protein purified Radiographic radiologic Result severity TST Tuberculosis vaccination [DOI] 10.7759/cureus.19882 PMC 바로가기 [Article Type] Internal Medicine
Oxidative damage and delayed replication allow viable Mycobacterium tuberculosis to go undetected산화 손상 및 지연된 복제로 인해 생존 가능한 결핵균이 발견되지 않음Article Published on 2021-11-242022-09-11 Journal: Science Translational Medicine [Category] SARS, 치료기술, [키워드] addition antimicrobial resistance Bacteria BCG cause of death Cell conditions coronavirus disease Coronavirus disease 2019 death DNA example implication Infection latency lipids mechanism Mycobacterium bovis Mycobacterium tuberculosis notable overcome oxidative stress pandemic phenotype phenotypic Proteins regimen regimens Relapse repair Replication Treatment Tuberculosis undergo undetectable [DOI] 10.1126/scitranslmed.abg2612 PMC 바로가기 [Article Type] Article