class – Page 5 – Communicable Diseases Research

Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants

다양한 SARS-CoV-2 변이체에 대한 삼중 백신 접종자의 기억 B 세포 레퍼토리

Article

Published on 2022-03-012022-09-11
Journal: Nature [Category] MERS, SARS, 변종, 진단,

[키워드] active against antibody Antibody titre B.1.1.529 B.1.351 Beta binding class complex defined determinant dose Effectiveness epitope Epitopes examined FIVE geometric geometric mean greater human monoclonal antibodies Human monoclonal antibody immunization inactivated individual Infection Local memory B cell memory B cells mice monoclonal antibodies mutated neutralization neutralize neutralized Neutralizing Neutralizing antibodies neutralizing antibody neutralizing monoclonal antibody omicron Protective raising Receptor-binding domain recipient recipients regimen sarbecovirus SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant sera seroconversion rate seroconversion rates Spike protein Structure subset target the receptor-binding domain therapy Treatment Vaccine vaccine doses vaccinee vaccinees variants of concern virus
[DOI] 10.1038/s41586-022-04466-x PMC 바로가기 [Article Type] Article

The impact of obesity on hospitalized patients with COVID-19 infection in the Eastern Province of Saudi Arabia

Observational Study

Published on 2022-03-012022-10-04
Journal: Journal of Medicine and Life [Category] 임상,

Identification-detection group testing protocols for COVID-19 at high prevalence

유병률이 높은 COVID-19에 대한 식별 감지 그룹 테스트 프로토콜

Article

Published on 2022-02-282022-09-10
Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 치료기술,

Individualized Constellation of Killer Cell Immunoglobulin-Like Receptors and Cognate HLA Class I Ligands that Controls Natural Killer Cell Antiviral Immunity Predisposes COVID-19

Genetics

Published on 2022-02-222022-10-31
Journal: Frontiers in Genetics [Category] COVID-19,

[키워드] absence activating acute respiratory syndrome anti-SARS-CoV-2 Antiviral antiviral immunity Asymptomatic Biomarker cause Cell characterized class Cognate Combination constellation Control controls coronavirus Coronavirus-2 COVID-19 COVID-19 cohort COVID-19 host genetics COVID-19 patient COVID-19 susceptibility Defense determine detrimental Frequency General population Genetic healthy HLA HLA association HLA class I HLA gene HLA-Bw4 Host Hypothesis individual individuals Infection Inflammatory cytokine KIR KIR receptors KIR-HLA KIR-HLA association KIR2DL2 + KIR2DS1 KIR2DS5 KIR3DL1 KIR3DL2 Ligand ligands majority maturation natural NK cell NK cell function NK cells offer outcome pathologic Patient patients hospitalized receptor reduce regulated responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility severe COVID-19 severe COVID-19 patient significantly lower subsequent tested the patient triggered variable with mild disease
[DOI] 10.3389/fgene.2022.845474 PMC 바로가기 [Article Type] Genetics

Latent Class Analysis of Health Behavior Changes Due to COVID-19 among Middle-Aged Korean Workers

Article

Published on 2022-02-062022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, COVID19(2023년), MERS, SARS,

HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 Severity

HLA-C*04:01 SARS-CoV-2 펩티드에 대한 HLA 클래스 I 이형접합 및 예측된 친화도에 영향을 미치고 아르메니아 환자의 연령 및 성별과 함께 COVID-19 심각도에 기여

Immunology

Published on 2022-02-032022-09-12
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] 95% CI advanced age affinity affinity to SARS-CoV-2 age Antigen Armenian population Armenians association Asymptomatic Asymptomatic COVID-19 AUC carriers change class contribute contributed Control COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 severity COVID-19 susceptibility decrease deficiency demographic variable disease severity disease symptom distribution dose-dependent manner Effect examined Frequency Genotype Health heterozygosity HLA HLA allele HLA classical genes HLA-B HLA-B*51:01 HLA-C HLA-C*04:01 HLA-C*04:01 allele HLA-I heterozygosity homozygous Hospitalization host immunity incidence Infection Interaction leukocyte loci Male sex outcome Patient patients peptide Personalized medicine predicted Prevalence Protective provided recognize risk SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 peptides severe COVID-19 severity severity risk modelling Sex significant increase significantly subgroup the disease the SARS-CoV-2 translated Variability
[DOI] 10.3389/fimmu.2022.769900 PMC 바로가기 [Article Type] Immunology

Effect of remote monitoring on clinical outcomes in European heart failure patients with an implantable cardioverter-defibrillator: secondary results of the REMOTE-CIED randomized trial

Randomized Controlled Trial

Published on 2022-02-022022-10-05
Journal: Europace [Category] COVID19(2023년), SARS, 임상,

In silico Analysis of SARS-CoV-2 ORF8-Binding Proteins Reveals the Involvement of ORF8 in Acquired-Immune and Innate-Immune Systems

Medicine

Published on 2022-02-012022-10-31
Journal: Frontiers in Medicine [Category] COVID-19,

[키워드] Analysis Antigen Autoimmunity binding candidate cellular class Cluster Clustering analysis coagulation cascade complement conserved contribute coronavirus Coronavirus infection COVID-19 COVID-19 pathogenesis dataset Degradation described downregulation Endoplasmic reticulum eukaryote eukaryotic genome sequence homology immune evasion in silico analysis Infection involved Involvement KEGG KEGG pathway analysis less leukocyte ORF8 ORF8 accessory gene ORF8 protein pathology performed Phylogenetic phylogenetic profiling physically predicted promote Protein Proteins SARS-CoV SARS-CoV-2 severe symptom Spread Stress suggested System tissue-specific expression variant of SARS-CoV-2 ward was performed wild-type SARS-CoV-2
[DOI] 10.3389/fmed.2022.824622 PMC 바로가기 [Article Type] Medicine

CRISPR-Cas3-based diagnostics for SARS-CoV-2 and influenza virus

Article

Published on 2022-01-302022-10-30
Journal: iScience [Category] COVID-19,

Predicted HLA Class I and Class II Epitopes From Licensed Vaccines Are Largely Conserved in New SARS-CoV-2 Omicron Variant of Concern

허가된 백신에서 예측된 HLA 클래스 I 및 클래스 II 에피토프는 우려의 새로운 SARS-CoV-2 오미크론 변이체에서 크게 보존됩니다

Immunology

Published on 2022-01-282022-09-11
Journal: Frontiers in Immunology [Category] 변종,