Clinical evaluation of rapid point-of-care antigen tests for diagnosis of SARS-CoV-2 infectionSARS-CoV-2 감염 진단을 위한 신속한 현장 진료 항원 검사의 임상 평가Original Article Published on 2021-05-222022-09-12 Journal: European Journal of Clinical Microbiology & Infect [Category] SARS, 진단, [키워드] 95% CI acute COVID-19 Antigen Characteristics clinical clinical sensitivity clinical specificity COVID-19 cycle threshold diagnosed diagnosing diagnosis of SARS-CoV-2 diagnostic evaluated FIVE gold standard Health care worker health care workers Infection infections lateral flow immunoassay Negative predictive value overcome Patient patient group patients POC test point-of-care positive Prevalence ranged Rapid rapid antigen test Rapid antigen tests respiratory specimen RT-qPCR SARS-CoV-2 sensitivity short duration specificity specimen study population Symptoms Test treated upper respiratory Variability Viral load [DOI] 10.1007/s10096-021-04274-7 PMC 바로가기 [Article Type] Original Article
Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patientsResearch Article Published on 2021-05-212022-10-28 Journal: PLoS ONE [Category] COVID-19, [키워드] 95% CI accounted addition age Capital clinical decision clinical sensitivity clinical suspicion clinically suspected Cohort conducted confirmed case COVID-19 COVID-19 cohort COVID-19 pandemic determine eligible epidemiological False negative rate Helsinki implication individual individuals Inpatient Laboratory management medical record moderate outpatients Patient patients positive reference standard Region Result Retrospective study RT-PCR RT-PCR test SARS-COV-2 infection SARS-CoV-2 RT-PCR SARS-CoV-2 RT-PCR test sensitivity study period symptomatic patient tested understanding women [DOI] 10.1371/journal.pone.0251661 PMC 바로가기 [Article Type] Research Article
Evaluation of 3 SARS-CoV-2 IgG Antibody Assays and Correlation with Neutralizing Antibodies3개의 SARS-CoV-2 IgG 항체 분석 및 중화 항체와의 상관관계 평가Article Published on 2021-04-292022-09-12 Journal: The journal of applied laboratory medicine [Category] MERS, SARS, 진단, [키워드] 95% CI Abbott acute phase antibody kinetics Characteristics clinical clinical sensitivity collected Combination comparable Concentration correlation COVID-19 Cutoff demonstrated DiaSorin Euroimmun evaluated healthy individual IgG IgG antibody IgG response individual Infection Neutralizing Neutralizing antibodies neutralizing antibody Neutralizing antibody response outbreak Patient positive Quantitative Respiratory illness SARS-CoV-2 SARS-CoV-2 IgG sensitivity sera serologic assay serology specificity specimen tested was determined [DOI] 10.1093/jalm/jfaa188 PMC 바로가기 [Article Type] Article
Evaluation of High-Throughput SARS-CoV-2 Serological Assays in a Longitudinal Cohort of Patients with Mild COVID-19: Clinical Sensitivity, Specificity, and Association with Virus Neutralization Test경증 COVID-19 환자의 세로 코호트에서 처리량 SARS-CoV-2 혈청학적 분석 평가: 임상 민감도, 특이도 및 바이러스 중화 테스트와의 연관성Article Published on 2021-04-292022-09-11 Journal: Clinical Chemistry [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] Antibody Response Antibody titers Area association AUC best can not clinical clinical sensitivity clinical specificity collected Concordance Course COVID-19 detect DiaSorin disease evaluated except for functional greater health-care Health-care workers healthcare worker IgA IgG IgM longitudinal lowest mild patient mild patients neutralization test Neutralizing antibodies neutralizing antibody neutralizing antibody titers Neutralizing titer ranged RBD Receptor binding domain ROC Curve RT-PCR S protein SARS-CoV-2 sensitivity sera serological Serological assay serological assays Serological tests serum Siemens specificity specimen subset Test the RBD the S protein Total Virus neutralization virus neutralization test VNT with COVID-19 [DOI] 10.1093/clinchem/hvaa336 PMC 바로가기 [Article Type] Article
Development and Clinical Evaluation of an Immunochromatography-Based Rapid Antigen Test (GenBody™ COVAG025) for COVID-19 Diagnosis코로나19 진단을 위한 면역크로마토그래피 기반 신속항원검사(GenBody™ COVAG025) 개발 및 임상 평가Article Published on 2021-04-292022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, 치료법, [키워드] 95% CI Antigen antigen detection test antigen test antigen tests assumed clinical clinical sensitivity Clinical studies clinically evaluated collected contributing to COVID-19 Ct values development Diagnosis Emergency use authorization faster global pandemic help immunoassay immunochromatographic immunochromatography in viral Isolation medium molecular Nasopharyngeal swab nasopharyngeal swabs nucleocapsid patients with COVID-19 PCR assay Rapid real-time RT-PCR RT-PCR RT-PCR assay SARS-CoV-2 SARS-CoV-2 nucleocapsid Sensitivity and specificity significantly significantly higher symptom onset symptomatic and asymptomatic Test tested transferred Transport transport medium Treatment Viral Viral load Viral transport medium VTM WHO guidelines [DOI] 10.3390/v13050796 PMC 바로가기 [Article Type] Article
Evaluation of RT-qPCR and Loop-Mediated Isothermal Amplification (LAMP) Assays for the Detection of SARS-CoV-2 in ArgentinaArticle Published on 2021-04-282022-10-31 Journal: Genes [Category] COVID-19, SARS, [키워드] amplified analyzed calculate calibrated clinical samples clinical sensitivity clinical specificity Concordance Consensus contribute detection diagnosis of SARS-CoV-2 diagnostic difference evaluate evaluated greater information isothermal amplification limit of detection log molecular N gene Pan polymerase chain positive provided ranged RdRp gene reference method RT-LAMP RT-qPCR SARS-CoV-2 sensitivity specificity Standard target gene the SARS-CoV-2 Variation was used WHO World Health Organization [DOI] 10.3390/genes12050659 PMC 바로가기 [Article Type] Article
Target specific serologic analysis of COVID-19 convalescent plasmaCOVID-19 회복기 혈장의 표적 특이적 혈청학적 분석Research Article Published on 2021-04-282022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] access anti-RBD assays Beckman Coulter Characteristics clinical clinical sample clinical sensitivity collected convalescent plasma coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 disease diagnosed with COVID-19 DiaSorin disease disease symptom disease symptoms Donor donors Elecsy Emergency False negative false negative result false negative results FDA IgG investigated LIAISON no difference Panel PCR plasma Roche Roche Diagnostics S1/S2 Sample SARS-CoV-2 SARS-CoV-2 IgG sensitivity serologic analysis serology serology assay specificity statistically significant difference target tested [DOI] 10.1371/journal.pone.0249938 PMC 바로가기 [Article Type] Research Article
Quantitative Measurement of Anti-SARS-CoV-2 Antibodies: Analytical and Clinical EvaluationAnti-SARS-CoV-2 항체의 정량적 측정: 분석 및 임상 평가Article Published on 2021-03-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analytical sensitivity analyzed Anti-SARS-CoV-2 S antibody Antibody Response Antibody testing Antibody titer causative agent claimed clinical clinical evaluation clinical sensitivity coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-reactivity detect determine diagnose Elecsy evaluated exhibited facilitate help highest immunoassays Infection Infectious disease interindividual variation limit linearity measure measurement Negative predictive value NPV Patient PCR positivity PCR-positive patient Positive predictive value PPV Predictive value Quality control quantitation Quantitative respiratory Roche Roche Diagnostics S protein SARS-CoV-2 sensitivity serologic assay serologic testing serology severe acute respiratory syndrome Coronavirus specificity specimen target the antibody response the S protein U/mL Vaccines Variation Virology while [DOI] 10.1128/JCM.03149-20 PMC 바로가기 [Article Type] Article
A Saliva-Based RNA Extraction-Free Workflow Integrated With Cas13a for SARS-CoV-2 DetectionSARS-CoV-2 검출을 위해 Cas13a와 통합된 타액 기반 RNA 추출 없는 워크플로Cellular and Infection Microbiology Published on 2021-03-162022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] SARS, 진단, 치료기술, [키워드] analytical sensitivity applied clinical samples clinical sensitivity comparable COVID-19 COVID-19 testing CRISPR CRISPR Diagnostics CRISPR-Cas13a detection diagnostics healthcare professionals heat inactivation Image analysis include limit of detection nucleic acid pandemic POC point-of-care positive quantification RNA RNA extraction RT-qPCR Saliva saliva samples SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA SARS-CoV-2 RNA detection sensitivity step Supply chain test results Treatment turn [DOI] 10.3389/fcimb.2021.632646 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Combined SARS-CoV-2 nucleic acid amplification testing and respiratory virus panel RT-PCR on the Hologic Panther Fusion systemArticle Published on 2021-03-102022-10-04 Journal: Journal of Clinical Virology [Category] SARS, 진단, 치료기술, [키워드] 95 % CI amplification carried Clinical diagnosis clinical sensitivity Cohen’s kappa coefficient Combined demonstrated diagnostic evaluate flexible fusion infection control Laboratory testing Mediated moderate nasopharyngeal objective other respiratory virus overlap pandemic Panel Panther Fusion positive provide respiratory respiratory pathogen respiratory virus respiratory viruses Result RT-PCR SARS-CoV-2 SARS-CoV-2 nucleic acid Significant specimen specimens Symptom virus [DOI] 10.1016/j.jcv.2021.104792 PMC 바로가기 [Article Type] Article