Machine Learning to Predict In-Hospital Mortality in COVID-19 Patients Using Computed Tomography-Derived Pulmonary and Vascular FeaturesArticle Published on 2021-06-032022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] Admission age build Chest computed tomography Chest CT Clinical data computer contributing to COVID-19 COVID-19 patient dataset death died discharge Features highlighting Hospitalization in-hospital mortality lung machine learning machine learning model Mann–Whitney U test median Metrics neural networks outcome parenchymal Patient patients patients who survived performed Precision Predictive Prognosis pulmonary pulmonary artery radiological recall reported SARS-COV-2 infection Stratification Support support vector machine SVM tomography Univariate analysis Vascular Vascular damage vector X-ray computed yielding [DOI] 10.3390/jpm11060501 PMC 바로가기 [Article Type] Article
Semen quality and windows of susceptibility: A case study during COVID-19 outbreak in ChinaObservational Study Published on 2021-06-012022-10-05 Journal: Environmental research [Category] SARS, 임상, [키워드] ambient association Bank candidate carried China collected computer Computer sperm analysis confounders COVID-19 COVID-19 outbreak determinant Donor evaluate Evidence exposure to finding Human identify indicated late stage male multivariate parameter parameters Pollution Pollution exposure positive Potential Regression model retrospective Semen Semen quality semen sample Sperm sperm motility susceptibility window Windows of susceptibility. [DOI] 10.1016/j.envres.2021.111085 PMC 바로가기 [Article Type] Observational Study
Rational design of potent anti-COVID-19 main protease drugs: An extensive multi-spectrum in silico approachResearch article Published on 2021-05-012022-10-05 Journal: The British journal of oral & maxillofacial surger [Category] 치료제, [키워드] acute respiratory syndrome analyzed annotations Antiviral approach ASINEX antiviral library binding affinity binding free energies binding free energy ChEMBL Compound computer coronavirus coronavirus disease COVID-19 crystal structure database drug candidate drug design Drug discovery end point enzyme etiological agent finding global pandemic Hydrogen bond in silico Approach in vivo inhibitor initial interactions MD simulation MM-PBSA molecular moves Novel coronavirus protease receptor Safe SARS-CoV-2 SARS-CoV-2 Mpro screening process similarity stability suggested Therapeutic strategies Virtual screening virus production was selected WaterSwap [DOI] 10.1016/j.molliq.2021.115636 [Article Type] Research article
Automatic detection of COVID-19 disease using U-Net architecture based fully convolutional networkResearch article Published on 2021-05-012022-10-05 Journal: Biomedical Signal Processing and Control [Category] 치료기술, [키워드] Accuracy acute respiratory syndrome affected Algorithm Analysis artificial Asymptomatic automated Automatic can be used caused chain China Clinicians computer coronavirus COVID-19 COVID-19 disease deep learning detection system develop disease early stage effective evaluated GitHub repository help indication intelligence Italian lack pandemic positive radiology reaction RT-PCR SARS-CoV-2 SARS-CoV-2 virus Sensitivity and specificity Society Symptom the disease U-Net architecture [DOI] 10.1016/j.bspc.2021.102518 [Article Type] Research article
Computational Identification of a Putative Allosteric Binding Pocket in TMPRSS2Molecular Biosciences Published on 2021-04-302022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] activated Activation acute respiratory syndrome allosteric pocket binding binding site camostat catalytic site computer conformational change coronavirus docking enzyme identification inactive induce inhibit inhibitor MD simulation Molecular dynamics simulation Molecular modeling N-terminal pocket Prevent promote proteolytic cleavage reported SARS-CoV-2 selective shown TMPRSS2 TMPRSS2 inhibitors TMPRSS2 protein transmembrane serine protease viral infection viruses [DOI] 10.3389/fmolb.2021.666626 PMC 바로가기 [Article Type] Molecular Biosciences
Virtualized clinical studies to assess the natural history and impact of gut microbiome modulation in non-hospitalized patients with mild to moderate COVID-19 a randomized, open-label, prospective study with a parallel group study evaluating the physiologic effects of KB109 on gut microbiota structure and function: a structured summary of a study protocol for a randomized controlled study입원하지 않은 경증에서 중등도의 COVID-19 환자에서 장내 미생물군유전체 조절의 자연사 및 영향을 평가하기 위한 가상화된 임상 연구 장내 미생물군 구조에 대한 KB109의 생리학적 효과를 평가하는 병렬 그룹 연구와 함께 무작위, 공개, 전향적 연구 및 기능: 무작위 대조 연구를 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-022022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] 1:1 24 hours Ability absence addition adhere Affect age Ageusia allergy analysed Anosmia Anosmia/ageusia Antacid Antibiotics Antiviral assessment assigned Autoimmune disease Bariatric surgery baseline bilevel positive airway pressure Biomarker Biomarkers biomarkers of inflammation BiPAP Blinding blocker Blood blood sample Blood samples both groups bowel bowel resection breath Care care provider Cell change Chest chest tightness chills chronic lung disease cirrhosis clinical clinical study clinical trial Cold collected Community Comorbidity comparator Patients completion Compliance component computer Concomitant medication concomitant medications concurrent condition conducted contraindications coronavirus disease Coronavirus disease 2019 cough COVID-19 COVID-19 in patient COVID-19 symptom COVID-19 symptoms COVID-19 testing COVID-19-related symptom COVID-19-related symptoms COVID-19–related symptom COVID-19–related symptoms CPAP Cytokines D-dimer daily dose Day defined diarrhea dissemination drug duration of symptom Effect element eligible Enrollment evaluate evaluate the effect evaluated exacerbated exclusion criteria exploratory fatigue fatty Fatty acid feasible Female patients Fever fiber Follow-up follow-up period following group Gut gut microbiome gut microbiome composition gut microbiota headache Health Health care Health Care Utilization Health status healthcare Histamine history hospital Hospital admission Hospital admissions Hospitalization Hospitalized hypoxia Identifier IgM/IgG Immunity immunomodulatory immunosuppressive immunosuppressive therapy in both group include Infection Inflammation Inflammatory biomarker Inflammatory bowel disease information Informed consent inhibitors intake Interaction investigational agent irritable bowel syndrome KB109 Laboratory laboratory measures lactating library life Liver disease Lung disease magnitude malignancy management measure Measures medication medications Medicine metabolite Microbiome microbiota Mild mild to moderate Mild to moderate COVID-19 mild to moderate disease moderate Moderate COVID-19 moderate disease modulate modulation muscle pain nasal congestion neutralization assays not limited nucleic acid number objective Open-label opinion other compound other compounds outcome outcome measure Outpatient outpatients oxygen oxygen saturation Oxygen therapy Pain parallel group participant Participation Patient patient population Period Physical examination positive airway pressure Positive test Potential pre-symptomatic pregnant Primary outcome progression proportion proportions Prospective Study PROTECT protocol protocols proton pump provided pulse Pulse oximeter Quality of life Quantitative question randomisation randomised randomised controlled study randomization Randomized randomized controlled study receive recruitment reduction Registered reported response resting position risk risk of infection Sample size screened selected self-care sensitivities Sequencing serological serology shaking short-chain fatty acids Shortness of breath Sleep sleep apnea Smartphone sore throat specific biomarker specific biomarkers Spread SSC Standard Stool stratified Study design Study protocol study visit supplementary material Swab Symptom symptomatic patient Symptomatic patients Symptoms syndrome Tablet TEAEs Telemedicine telephone temperature the patient The United States therapy time Tolerability Treatment treatment-emergent adverse event undergo United States unlikely Viral Viral load water website worsening [DOI] 10.1186/s13063-021-05157-0 PMC 바로가기 [Article Type] Letter
COVID-19 and Computer Audition: An Overview on What Speech & Sound Analysis Could Contribute in the SARS-CoV-2 Corona CrisisDigital Health Published on 2021-03-292022-10-31 Journal: Frontiers in Digital Health [Category] COVID-19, [키워드] Analysis appear automatically Computational paralinguistics computer computer audition Corona Corona virus coughing COVID-19 COVID-19 disease crisis death Diagnosis Effects effort help implementation include limitation machine listening outbreak Pain pandemic Patient provide Registered risk SARS-CoV-2 social distancing sound speech Spread Symptom the epidemic the SARS-CoV-2 Treatment virus [DOI] 10.3389/fdgth.2021.564906 PMC 바로가기 [Article Type] Digital Health
A Study of a New Technique of the CT Scan View and Disease Classification Protocol Based on Level Challenges in Cases of Coronavirus DiseaseResearch Article Published on 2021-03-182022-10-29 Journal: Radiology Research and Practice [Category] COVID-19, [키워드] approach chain challenge Chest Chest CT Chest CT image Chest CT images classification CNNs complement computer computer tomography coronavirus disease coronavirus disease COVID-19 COVID-19 COVID-19 patients CT scan dataset diagnose Diagnosis diagnostic Efficacy form High-resolution HRCT IMPROVE Level Lung diseases Mild network Neural New noninvasive participant Patient performed Pneumonia processed protocol Radiological Diagnosis radiological finding Radiologists reaction reduce researcher RT-PCR shown significantly higher technique View was used with COVID-19 [DOI] 10.1155/2021/5554408 PMC 바로가기 [Article Type] Research Article
Six artificial intelligence paradigms for tissue characterisation and classification of non-COVID-19 pneumonia against COVID-19 pneumonia in computed tomography lungs컴퓨터 단층 촬영 폐에서 COVID-19 폐렴에 대한 비COVID-19 폐렴의 조직 특성화 및 분류를 위한 6가지 인공 지능 패러다임Article Published on 2021-03-012022-09-11 Journal: International Journal of Computer Assisted Radiolo [Category] SARS, 치료기술, [키워드] Accuracy Analysis artificial intelligence AUC automatically Bispectrum characterisation classification CNN Cohort Computed tomography computer computer tomography consolidations COVID COVID pneumonia COVID-19 COVID-19 pandemic deep deep learning feasible feature GGO Ground-glass opacities ground-glass opacity high correlation Hypothesis hypothesise Inference Italian lung machine machine learning mechanism Non-COVID-19 offer p-values pandemic Patient patients performance pleural effusion Pneumonia protocol radiological risk separated severity Stratification suggested the disease tissue transfer transfer learning Vaccines validation was used [DOI] 10.1007/s11548-021-02317-0 PMC 바로가기 [Article Type] Article
A Review on Deep Learning Techniques for the Diagnosis of Novel Coronavirus (COVID-19)Biomedical Engineering Published on 2021-02-102022-10-30 Journal: Ieee Access [Category] COVID-19, [키워드] clinician computer computer tomography coronavirus COVID-19 COVID-19 diagnosis data set deep deep learning Deep Learning Method Deep transfer learning Diagnosis diagnosis of COVID-19 facilitate globe highlight learning measure novel outbreak pandemic powerful tool Prevalence provide raised Research researcher review rising technique Vaccine X-ray [DOI] 10.1109/ACCESS.2021.3058537 PMC 바로가기 [Article Type] Biomedical Engineering