A Bispecific Antibody Targeting RBD and S2 Potently Neutralizes SARS-CoV-2 Omicron and Other Variants of ConcernRBD 및 S2를 표적으로 하는 이중특이성 항체는 SARS-CoV-2 오미크론 및 우려되는 기타 변이체를 잠재적으로 중화합니다Article Published on 2022-08-242022-09-11 Journal: Journal of Virology [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Alpha antibodies antibody B.1.1.7 B.1.351 B.1.617.1 B.1.617.2 Beta binding bispecific antibodies breadth Breakthrough infection caused concern contagious coronavirus country COVID-19 COVID-19 vaccines Delta demonstrated domain dominant effective Efficacy epitope Epitopes feasible highlighting IMPROVE mAbs monoclonal antibody Mutation neutralization neutralize Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody omicron Omicron variant Omicron variants Other other variant other variants parental Prevent Pseudotyped virus RBD Receptor-binding domain reduced respiratory retained SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 variants SARS-CoV-2 WT specificity Spike protein target targeting tested the spike protein therapeutic treat Vaccine variant variants variants of concern VoC VOCs wild-type [DOI] 10.1128/jvi.00775-22 PMC 바로가기 [Article Type] Article
Electronic field effect detection of SARS-CoV-2 N-protein before the onset of symptoms증상 발현 전 SARS-CoV-2 N-단백질의 전자장 효과 검출Article Published on 2022-08-152022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition antibodies biosensor Boron buffer cause contagious coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic detect develop effort FET gel Graphene infected individual infected individuals investigated less limit of detection linear lowest magnitude N-protein nitrogen onset of symptom pandemic platform proof researcher robust SARS-CoV-2 SARS-CoV-2 nucleocapsid sensitivity severe acute respiratory syndrome Coronavirus transducer Viral protein [DOI] 10.1016/j.bios.2022.114331 PMC 바로가기 [Article Type] Article
Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater폐수에서 SARS-CoV-2 돌연변이 모니터링을 위한 RT-ddPCR과 표적 앰플리콘 시퀀싱의 직접 비교Article Published on 2022-08-102022-09-11 Journal: The Science of the total environment [Category] Coronavirus, COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Amplicon sequencing Analysis analyzed applied approach ARTIC association breakthrough infections characteristic contagious Course Coverage COVID-19 pandemic determined by Direct Epidemiology event FIVE gold gold standard highlighting Mutation mutations over positive quantification quantitative measurement referred to reported RT-ddPCR SARS-CoV-2 SARS-CoV-2 mutation SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Sequencing variants variants of concern variants of concern (VOC) variants of SARS-CoV-2 VOCs wastewater wastewater-based epidemiology (WBE) [DOI] 10.1016/j.scitotenv.2022.155059 PMC 바로가기 [Article Type] Article
Tempo-Spatial Modelling of the Spread of COVID-19 in Urban Spaces도시 공간에서 COVID-19의 확산에 대한 시공간 모델링Article Published on 2022-08-082022-09-11 Journal: International Journal of Environmental Research an [Category] 변종, [키워드] Analysis approach changed city consequence contagious contagious disease COVID-19 COVID-19 pandemic disease disparity distribution evaluate Evolution exceptional explain greater increasingly Infection intensity Malaga pandemic Perspective selected shown social areas social structure socio-spatial structure Space Spain Spread statistical statistical analysis theory urban urban spaces. variable variant [DOI] 10.3390/ijerph19159764 PMC 바로가기 [Article Type] Article
Modern drug discovery applications for the identification of novel candidates for COVID-19 infectionsReview article Published on 2022-08-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 변종, 신약개발, 유전자 메커니즘, 치료기술, 치료제, [키워드] alkaloids Analysis candidate Characteristics Compound computational contagious coronavirus cough COVID-19 COVID-19 infection diagnosed Drug discovery effective Epidemic Evolution Fever Glycosides Illness severity in silico Infection investigated minor symptom molecular docking Numerous occurred outbreak plasma Pneumonia predicted reduce required researcher RNA RT-PCR shown Spread Symptoms terpenoids the disease therapeutic therapy Transmission Travel Treatment vaccination virus World Health Organization Wuhan, China [DOI] 10.1016/j.amsu.2022.104125 [Article Type] Review article
The burden of monkeypox virus amidst the Covid-19 pandemic in Africa: A double battle for AfricaShort communication Published on 2022-08-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 치료기술, [키워드] Africa2 African caused clinical symptom contagious contributing to country COVID-19 COVID-19 cases Critical cross-protective immunity declining disease Disease surveillance Diseases effort fatigue Fever General population headache healthcare facility healthcare professionals Healthcare system impacted include inoculated International knowledge lack less Monkeypox Monkeypox virus MOST one health pandemic Rash risk Still Surveillance Symptom the disease Treatment vaccination Vaccine viral disease virus WHO zoonotic [DOI] 10.1016/j.amsu.2022.104197 [Article Type] Short communication
Online cognitive behavioural therapy as a psychological vaccine against stress during the COVID-19 pandemic in pregnant women: A randomised controlled trialRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: Journal of psychiatric research [Category] Coronavirus, 임상, [키워드] affected Anxiety behavioural cognitive Cognitive behavioural therapy consequence contagious COVID-19 COVID-19 pandemic Depression Efficacy greater Intervention management pandemic participated Perceived stress Pregnancy pregnant pregnant women Psychological Psychopathology randomised randomised controlled trial Resilience Spain Stress Support group Symptom Symptoms therapy Treatment Trial Vaccine were assessed women [DOI] 10.1016/j.jpsychires.2022.07.016 PMC 바로가기 [Article Type] Randomized Controlled Trial
PCovNet: A presymptomatic COVID-19 detection framework using deep learning model using wearables dataPCovNet: 웨어러블 데이터를 사용하는 딥 러닝 모델을 사용하는 전증상 COVID-19 감지 프레임워크Article Published on 2022-08-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, [키워드] abnormality Achille Administered Anomaly anomaly detection autoencoder average Chain Reaction circumvent contagious COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 pandemic dataset deep learning detect Diagnosis diagnostic evaluated feasibility framework healthcare heart heart rate individual Long Long short-term memory management protocol presymptomatic provoke Rate recall resting Resting heart rate Reverse transcription-polymerase chain reaction RT-PCR Secondary diagnosis Short-Term Memory smartwatch span Spread subject Symptom symptom onset Transmission Variational autoencoder. viral pathogen while [DOI] 10.1016/j.compbiomed.2022.105682 PMC 바로가기 [Article Type] Article
Reverse vaccinology approach for multi-epitope centered vaccine design against delta variant of the SARS-CoV-2Article Published on 2022-08-012022-11-16 Journal: Environmental science and pollution research inter [Category] COVID19(2023년), SARS, 변종, [키워드] addition adverse effect Alpha applied approach Asia B-cell chimeric Chimeric vaccine conserved contagious COVID-19 COVID-19 infection COVID-19 outbreak CTL epitope Delta delta variant docking Efficacy effort elicit Epitopes expression faster globe highly antigenic HLA HTL humoral immune response Immune simulation impacted in silico India induce infective Multi-epitope vaccine Mutation non-allergenic other variant Protein reported reverse vaccinology SARS-CoV-2 South spike Spike protein the SARS-CoV-2 the spike protein TLR4 transmission rate USA Vaccine vaccine construct Vaccine design Vaccines variant variants of concern variants of SARS-CoV-2 was performed Wuhan, China [DOI] 10.1007/s11356-022-19979-1 PMC 바로가기
The accuracy of machine learning approaches using non-image data for the prediction of COVID-19: A meta-analysisReview article Published on 2022-08-012022-10-05 Journal: International journal of medical informatics [Category] 진단, [키워드] Accuracy assessment can be used characteristic contagious covariate COVID-19 database diagnostic Diagnostic test accuracy disease eligible feasible heterogeneity identify inclusion criteria machine learning approach machine learning model machine learning models material Meta-analysis objective predict Quality Result sensitivity Sensitivity and specificity specificity suggested were used [DOI] 10.1016/j.ijmedinf.2022.104791 [Article Type] Review article