COVID-19 pathology – Page 5 – Communicable Diseases Research

A Dual-Route Perspective of SARS-CoV-2 Infection: Lung- vs. Gut-specific Effects of ACE-2 Deficiency

Pharmacology

Published on 2021-06-112022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

Immunomodulation: Immunoglobulin Preparations Suppress Hyperinflammation in a COVID-19 Model via FcγRIIA and FcαRI

면역 조절 : 면역 글로불린 제제는 FcγRIIA 및 FCαRI를 통해 COVID-19 모델에서 과인 염증을 억제합니다.

Immunology

Published on 2021-06-102022-08-31
Journal: Frontiers in Immunology [Category] MERS, SARS, 바이오마커, 진단,

[키워드] “cytokine storm” Activation addition Anti-inflammatory antibody cells characterized Clinical outcome coated with convalescent plasma COVID-19 COVID-19 disease COVID-19 pathology cytokine cytokine release Cytokine storm dissect drug dysregulated immune response elicit Fc-receptors FcγR followed by form functional global pandemic highlighting HL60 human immunoglobulin IgA IgG IgG and IgM IgM antibodies immune complex immune modulation immune modulatory drug immune modulatory drugs immune response Immunoglobulin immunoglobulins IMPROVE in vitro model include Inflammation Inflammatory Intravenous immunoglobulin ITAMi IVIG Model neutrophil Neutrophils pathology patients phagocytosis preparation reduced SARS-CoV-2 severe COVID-19 patients severe forms of COVID-19 Signaling Spike protein Spread tested therapeutic trimodulin
[DOI] 10.3389/fimmu.2021.700429 PMC 바로가기 [Article Type] Immunology

SARS-CoV-2 Viral Entry Proteins in Hyperandrogenemic Female Mice: Implications for Women with PCOS and COVID-19

안드로겐과다증 암컷 마우스의 SARS-CoV-2 바이러스 진입 단백질: PCOS 및 COVID-19가 있는 여성에게 미치는 영향

Article

Published on 2021-04-252022-09-12
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 진단,

[키워드] ACE2 ACE2 mRNA ACE2 protein ADAM ADAM17 Affect androgen Androgen receptor androgens angiotensin angiotensin I angiotensin I converting enzyme 2 Body body composition body weight Brain cardiometabolic cathepsin cathepsin L causative agent cecum characterized Comorbidities COVID-19 COVID-19 pathology determined by Dihydrotestosterone disorder downregulated dysfunction elevated ELISA Endocrine enzyme fasting fasting glucose fat furin Glucose heart highlight host cell host cells host proteases hyperandrogenism infect kidney lean mass lung male mass mice morphology Mortality mRNA multiple tissue multiple tissues obesity organ systems ovarian Ovary ovulatory pathology Patient Polycystic polycystic ovary Polycystic ovary syndrome priming protease proteases Tmprss2 Protein protein level protein levels qPCR quantified receptor regulate renal risk risk factor Risk factors RT-qPCR SARS-CoV-2 SARS-CoV-2 entry serum severe COVID-19 severity small intestine tissues TMPRSS2 TMPRSS4 treated Treatment upregulated Urine was determined was measured Western-blot with COVID-19 women
[DOI] 10.3390/ijms22094472 PMC 바로가기 [Article Type] Article

Long-COVID and Post-COVID Health Complications: An Up-to-Date Review on Clinical Conditions and Their Possible Molecular Mechanisms

장기간의 코로나바이러스 및 코로나바이러스 이후의 건강 합병증: 임상 상태 및 가능한 분자 메커니즘에 대한 최신 검토

Review

Published on 2021-04-182022-09-01
Journal: Viruses [Category] MERS, SARS, 유전자 메커니즘, 진단,

[키워드] abdominal pain Acute myocardial infarction acute respiratory syndrome adverse effects adverse outcome affected anorexia Anxiety Arthritis Ataxia Atherosclerosis Blood coagulation cardiac hypertrophy cardiovascular system Care cerebral hemorrhage characterized clinical condition conducted Confusion constipation convulsions Coronary artery COVID-19 COVID-19 pandemic COVID-19 pathology cytokine Cytokine storm Depression diarrhea disease Diseases Dizziness Effects endothelial fibrosis gastrointestinal hemorrhage Guillain–Barrè syndrome Headaches Health hematological hemiplegia Hemostasis immune system Immune-mediated impaired consciousness imperative Inflammation Inflammatory Kawasaki disease lack lack of appetite Local long-COVID Long-term care loss of taste Lupus mechanism mental health MERS Microvascular thrombosis Middle East Middle East respiratory syndrome molecular mechanism molecular mechanisms multiple organ failures Myocardial myocardial fibrosis nausea nausea/vomiting nervous system outcome Pain pathophysiological pathophysiology pediatric Pneumonia psoriasis Pulmonary embolism pulmonary fibrosis pulmonary system Pulmonary thromboembolism renal system respiratory Respiratory failure review rheumatoid arthritis Severe acute respiratory syndrome Stress stroke Survivors syndrome systemic effects Thromboembolism thrombosis Vascular Vascular damage visual impairment vomiting
[DOI] 10.3390/v13040700 PMC 바로가기 [Article Type] Review

Neurotropic Viruses, Astrocytes, and COVID-19

Neuroscience

Published on 2021-04-092022-10-31
Journal: Frontiers in Cellular Neuroscience [Category] COVID-19,

COVID-19 Management in the Pediatric Age: Consensus Document of the COVID-19 Working Group in Paediatrics of the Emilia-Romagna Region (RE-CO-Ped), Italy

Review

Published on 2021-04-082022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS,

[키워드] accumulated acute respiratory syndrome age approach Care carried caused Characteristics children clinical experience Clinical management Consensus coronavirus coronavirus disease COVID-19 COVID-19 pathology criteria database death defined develop document Emilia-Romagna group Health highlight hospital Hospitalization include infected children Italy knowledge literature majority management MIS-C not affected paediatrics pandemic pediatric pediatrics problem professional reduction in Region Research resulting SARS-CoV-2 SARS-COV-2 infection Severe case Spread structures the SARS-CoV-2 therapeutic Treatment working
[DOI] 10.3390/ijerph18083919 PMC 바로가기 [Article Type] Review

Association of alpha-1-antitrypsin deficiency with vitamin D status: who is most at risk of getting severe COVID-19?

알파-1-항트립신 결핍과 비타민 D 상태의 연관성: 중증 COVID-19에 걸릴 위험이 가장 높은 사람은 누구입니까?

Article

Published on 2021-04-012022-09-12
Journal: Inflammation research : official journal of the Eu [Category] MERS, 진단,

A Resource for the Network Representation of Cell Perturbations Caused by SARS-CoV-2 Infection

SARS-CoV-2 감염으로 인한 세포 교란의 네트워크 표현을 위한 리소스

Article

Published on 2021-03-222022-09-10
Journal: Genes [Category] SARS, 유전자 메커니즘, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect approach approaches can be used causal network causal relationships caused cell physiology cellular cellular pathway cellular phenotype cellular phenotypes contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pathology drug effective effort enrichment analysis etiology framework functional Health high-throughput experiments hypothese information inhibitor inhibitors lack list majority molecular mechanism molecular mechanisms network offer pandemic pathology Pathways Perturbation produced Protein Proteins reported representation resource respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus Signaling signaling pathways subset the coronavirus disease 2019 (COVID-19) Therapeutic strategies Treatment Viral viral infection
[DOI] 10.3390/genes12030450 PMC 바로가기 [Article Type] Article

Microglia Fighting for Neurological and Mental Health: On the Central Nervous System Frontline of COVID-19 Pandemic

Neuroscience

Published on 2021-02-182022-10-31
Journal: Frontiers in Cellular Neuroscience [Category] COVID-19,

[키워드] acute respiratory syndrome Affect affected alterations Brain cells Central nervous system CNS conditions contribute contributing to coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pathology COVID-19 patient COVID-19 patients Cytokines explain Fighting function functions General population groups homeostasis homeostatic hypoxia individual infected individuals Inflammatory response Invasion involved manifestation mental health disorders microglia modify molecular morphology nervous neurological neurological manifestations neurotoxic non-infected pandemic Psychiatric Psychosocial Psychosocial stress reported response responses against resulting SARS-CoV-2 Stress Symptom System systemic inflammatory responses
[DOI] 10.3389/fncel.2021.647378 PMC 바로가기 [Article Type] Neuroscience

Chemosensory Systems in COVID-19: Evolution of Scientific Research

Review

Published on 2021-02-092022-10-28
Journal: ACS chemical neuroscience [Category] COVID-19, MERS,