Critical – Page 5 – Communicable Diseases Research

Multiplex Hybrid Antigen-Capture LC-MRM Quantification in Sera and Nasal Lining Fluid of AZD7442, a SARS-CoV-2-Targeting Antibody Combination

Article

Published on 2022-11-012022-11-15
Journal: Analytical Chemistry [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제,

Proteomic analysis and identification reveal the anti-inflammatory mechanism of clofazimine on lipopolysaccharide-induced acute lung injury in mice

Article

Published on 2022-11-012022-11-15
Journal: Inflammation research : official journal of the Eu [Category] 유전자 메커니즘, 진단,

[키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome alleviate Analysis Anti-inflammatory anti-inflammatory property anti-inflammatory response ARDS CFZ Clofazimine coronavirus disease COVID-19 Critical decrease disease Diseases distress down-regulate histological change hyperimmune response IL-1β immune IMPROVE increasingly Infectious disease Inflammatory information inhibit involved lipopolysaccharide LPS lung Lung injury Macrophage macrophages mechanism mice Molecular biology pathway pharmacological mechanism potential molecular profile proliferation protective effect Protein protein expression Proteomic analysis proteomics Pulmonary edema Quantitative Signal transduction Signaling significantly survival rate syndrome therapeutic strategy TNF-α
[DOI] 10.1007/s00011-022-01623-w PMC 바로가기

Targeting SARS-CoV-2 papain-like protease in the postvaccine era

Article

Published on 2022-11-012022-11-15
Journal: Trends in pharmacological sciences [Category] SARS, 치료제,

Genome-wide detection of human variants that disrupt intronic branchpoints

Article

Published on 2022-11-012022-11-16
Journal: Proceedings of the National Academy of Sciences of [Category] 변종,

Examining the impact of trimester of diagnosis on COVID-19 disease progression in pregnancy

Research article

Published on 2022-11-012022-10-05
Journal: American journal of obstetrics & gynecology MFM [Category] 치료기술,

[키워드] Affect Asymptomatic Blood COVID-19 diagnosis COVID-19 disease COVID-19 disease progression COVID-19 disease severity COVID-19 illness COVID-19 in pregnancy COVID-19 infection criteria Critical defined develop diagnosed with COVID-19 Diagnosis Disease progression evaluate the effect evaluated Examining Features Frequency had more Hispanic hospital Hospital admission Infection initially asymptomatic patient Maternal morbidity Mild mild infection Mild symptom moderate morbidity Neonatal Neonatal morbidity no significant difference not differ Older outcome outcomes pandemic Patient patients patients with asymptomatic Positive test Pregnancy pregnant patient pregnant patients progression prospective cohort study SARS-CoV-2 SARS-CoV-2 in pregnancy severity Stillbirth stratified symptomatic infection symptomatic patient Symptoms the timing trimester of infection Universal was performed
[DOI] 10.1016/j.ajogmf.2022.100728 [Article Type] Research article

Covid-MANet: Multi-task attention network for explainable diagnosis and severity assessment of COVID-19 from CXR images

Research article

Published on 2022-11-012022-10-05
Journal: Sensors (Basel, Switzerland) [Category] 진단, 치료기술,

[키워드] Accuracy approach assigned automated Bacterial chest X-ray CNN conducted COVID-19 COVID-19 case COVID-19 cases COVID-19 diagnosis COVID-19 disease COVID-19 infection Critical CXR dataset deep learning develop Diagnosis disease early diagnosis eight experiment Explainable AI False negative Final first stage Health highlight IMPROVE Infection Infection Segmentation initial Interpretation lung Lung segmentation Lungs measure Mild moderate outbreak outperform Pneumonia predicted proportion quantification radiological examination reduced Region reported Research research finding RT-PCR test scoring system sensitivity sensitivity analysis severity severity of COVID-19 Stage Support transfer learning Tuberculosis Viral pneumonia with COVID-19
[DOI] 10.1016/j.patcog.2022.108826 [Article Type] Research article

Evaluation of Procalcitonin’s Utility to Predict Concomitant Bacterial Pneumonia in Critically Ill COVID-19 Patients

Article

Published on 2022-11-012022-11-15
Journal: Journal of Intensive Care Medicine [Category] 바이오마커,

[키워드] Antibiotic therapy AUC Bacteremia Bacterial Bacterial infection bacterial pneumonia baseline characteristics Concomitant conducted COVID-19 creatinine Critical Critical illness Critically ill patient Culture defined determine diagnosing diagnostic ENhance evaluate group hospitalized patients ICU ICU patient identify Ill in-hospital mortality intensive care intensive care unit Mortality multivariable multivariable model no difference no significant difference offer outcome Patient PCT Pneumonia positive predict Predictive procalcitonin receiver operating characteristics Regression model retrospective cohort study ROC SARS-CoV-2 secondary bacterial pneumonia serum creatinine Severe COVID-19 pneumonia Severity of disease specificity threshold utility variable vital signs was used while with COVID-19
[DOI] 10.1177/08850666221108636 PMC 바로가기

Third dose of COVID-19 mRNA vaccine appears to overcome vaccine hyporesponsiveness in patients with cirrhosis

Article

Published on 2022-11-012022-11-16
Journal: Journal of hepatology [Category] SARS, 변종,

[키워드] 95% CI appear B.1.1.529 B.1.617.2 BNT BNT162b2 BNT162b2 mRNA booster booster dose chronic liver disease cirrhosis compensated Control control group COVD-19 COVID-19 COVID-19 in patient COVID-19 vaccines COVID-19-related death Critical dose doses General population greater hepatic decompensation hyporesponsiveness immune dysregulation liver magnitude moderate Moderate COVID-19 Moderna mRNA-1273 vaccine mRNA vaccine mRNA-1273 outcome overcome participant Patient Pfizer predominant receipt reduction in retrospective cohort study risk of infection Support symptomatic the vaccine Vaccine Vaccines variants veteran with COVID-19
[DOI] 10.1016/j.jhep.2022.07.036 PMC 바로가기

Comparative epidemiology of five waves of COVID-19 in Mexico, March 2020-August 2022

Article

Published on 2022-10-312022-11-16
Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] 95% CI age analyzed Antigen association average calculated Care case fatality rates Comorbidities Comparative confirmed case confirmed cases COVID-19 COVID-19 case Critical death declined decrease Demographic factors Epidemic epidemic wave epidemiological Epidemiology estimates Factors Fatality rate FIVE Gender Health highest hospital Hospital admission Hospitalization hospitalizations Hospitalized In-hospital In-hospital death in-hospital mortality incidence increase in individual Intubated intubation intubations laboratory-confirmed male Metrics notable omicron pandemic Patient patients with comorbidities recorded reduction in Regression model risk SARS-CoV-2 second wave security severe disease severity subsequent Surveillance symptoms onset System vaccination variant were recorded
[DOI] 10.1186/s12879-022-07800-w PMC 바로가기

ColdZyme® protects airway epithelia from infection with BA.4/5

Article

Published on 2022-10-312022-11-16
Journal: Respiratory Research [Category] COVID19(2023년), SARS, 변종,