CRP levels – Page 5 – Communicable Diseases Research

Cardiac Troponin I Levels in Hospitalized COVID-19 Patients as a Predictor of Severity and Outcome: A Retrospective Cohort Study

Cardiology

Published on 2021-03-232022-10-31
Journal: Cureus [Category] COVID-19,

The Role of Immunological and Clinical Biomarkers to Predict Clinical COVID-19 Severity and Response to Therapy—A Prospective Longitudinal Study

임상 COVID-19 심각도 및 치료에 대한 반응을 예측하기 위한 면역학적 및 임상적 바이오마커의 역할 - 전향적 종단 연구

Immunology

Published on 2021-03-172022-08-31
Journal: Frontiers in Immunology [Category] 바이오마커, 치료제,

[키워드] acute respiratory distress syndrome Admission age and sex amplified association baseline Biomarker Blood blood sampling C-reactive protein C-reactive protein (CRP clinical Cohort coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity CRP CRP level CRP levels cytokine Cytokine storm Dexamethasone discharge disease disease severity elevated hospital discharge Hospitalized IL-6 interleukin interleukin-6 IQR Kinetics laboratory investigation longitudinal marker NIC non-infectious offer Patient patients patients hospitalized patients treated Predictive Predictive value predictor pro-inflammatory pro-inflammatory markers Prospective recruited reduction Remdesivir response Result role SARS-CoV-2 SARS-CoV-2 positive patient Sepsis serum Serum IL-6 severe coronavirus disease Staphylococcus aureus Staphylococcus aureus bacteraemia the SARS-CoV-2 the strongest timepoints treatment group treatment groups vital sign vital signs was performed
[DOI] 10.3389/fimmu.2021.646095 PMC 바로가기 [Article Type] Immunology

Defining Kawasaki disease and pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection during SARS-CoV-2 epidemic in Italy: results from a national, multicenter survey

이탈리아에서 SARS-CoV-2 유행 중 SARS-CoV-2 감염과 일시적으로 연관된 가와사키병 및 소아 염증성 다계 증후군 정의: 국가, 다기관 설문조사 결과

Observational Study

Published on 2021-03-162022-09-01
Journal: Pediatric Rheumatology Online Journal [Category] SARS, 임상, 진단,

[키워드] abnormality Acetylsalicylic acid age cardiac Cardiogenic shock characterized Chi square Chi square test Child child health children Clinical characteristics clinical feature Clinical features clinical manifestation clinical manifestations Cohort collected Complication complications Coronary artery Coronary artery abnormalities CRP levels database deaths demographic determine diagnosed disease elevated enrolled Evidence exact Fisher test ferritin Florence glucocorticoid Glucocorticoids group hospital Hypotension ICU admission Immunoglobulin immunoglobulins Inflammatory inflammatory disease Inflammatory diseases information IRCCS Italian IVIG Kawasaki disease laboratory data lymphopenia Mann-Whitney test Maternal multicenter Multisystem inflammatory syndrome associated with coronavirus disease myocarditis National no statistical difference Occurrence Older Older age outcome Patient patients pediatric Pediatric inflammatory multisystem syndrome-temporally associated to SARS-CoV-2 infection PIMS positive relationship respiratory response to treatment Result risk SARS-CoV-2 SARS-CoV-2 epidemic SARS-COV-2 infection Shock significantly similarities similarity Society supplementary material syndrome Treatment Treatment response Trieste troponin Troponin-T two groups were used
[DOI] 10.1186/s12969-021-00511-7 PMC 바로가기 [Article Type] Observational Study

Clinical features and risk factors of COVID-19-associated liver injury and function: A retrospective analysis of 830 cases

코로나19 관련 간 손상의 임상적 특징과 위험인자 및 기능: 830건의 후향적 분석

Article

Published on 2021-03-012022-09-11
Journal: Annals of hepatology [Category] MERS, SARS, 바이오마커,

[키워드] 95% confidence interval abnormality Admission aims Alanine Alanine transaminase ALT Analysis aspartate Aspartate transaminase AST AST/ALT Betacoronavirus Biochemistry C-reactive protein C-reactive protein (CRP Causality change clinical Clinical features Cohort comparison Computed tomography COVID-19 patients CRP level CRP levels demographic determine Diagnostic Criteria drug Drug induced liver injury elevated exhibited Factor feature groups hepatic Hepatic insufficiency hospitalized COVID-19 patient hospitalized COVID-19 patients incidence information Laboratory testing liver Liver injury lymphocyte multivariable logistic regression Multivariable regression Odds ratio on admission outcome parameter Patient performed Pneumonia potential risk proportion ranged Retrospective analysis risk factor Risk factors tomography Triglyceride was used were used X-ray
[DOI] 10.1016/j.aohep.2020.09.011 PMC 바로가기 [Article Type] Article

Effectiveness of mid-regional pro-adrenomedullin (MR-proADM) as prognostic marker in COVID-19 critically ill patients: An observational prospective study

COVID-19 중환자에서 예후 마커로서 중부 프로아드레노메둘린(MR-proADM)의 효과: 관찰 전향 연구

Observational Study

Published on 2021-02-082022-08-13
Journal: PLoS ONE [Category] Biochemistry, MERS, 바이오마커, 임상,

[키워드] 48 hour 48 hours 95% confidence interval adjusted Admission age AUC best Biomarkers C-reactive protein cardiovascular disease characterized COVID-19 COVID-19 adult patient COVID-19 ICU-patients COVID-19 patients COVID-19-ICU-patients Critically ill CRP CRP level CRP levels cut-off D-dimer diabetes Diabetes Mellitus dying patient dying patients effective Effectiveness enrolled explain Gender group higher mortality characterized patients ICU ICU admission increase in Laboratory Laboratory test Lactate lactate dehydrogenase LDH log-rank test logistic regression model lymphocyte Lymphocytes lymphocytopenia mechanism mid-regional pro-adrenomedullin Mortality MR-proADM MR-proADM measurement non-survivor NT-pro-BNP objective Odds ratio overall mortality Patient patients PCT predict Predictive procalcitonin Prognostic marker Prospective Study receiver-operating characteristics curves Referral responsible Result significantly Support survival curve Survival curves surviving and non-surviving patients tested university hospital were measured
[DOI] 10.1371/journal.pone.0246771 PMC 바로가기 [Article Type] Observational Study

Effects of tocilizumab on mortality in hospitalized patients with COVID-19: a multicentre cohort study

COVID-19로 입원한 환자의 사망률에 대한 토실리주맙의 효과: 다기관 코호트 연구

Multicenter Study

Published on 2021-02-012022-09-11
Journal: Clinical microbiology and infection : the official [Category] MERS, SARS, 진단, 치료기술,

[키워드] 95% confidence interval adjusted adjusted hazard ratio Admission analysed Analysis association baseline C-reactive protein C-reactive protein (CRP causal relationship clinical trial clinical trials cohort study control group coronavirus disease Coronavirus disease 2019 covariate COVID-19 CRP CRP levels death deaths determine Effect Efficacy Exploratory subgroup analyses hazard ratio hospitalized patient hospitalized patients ICU ICU admission implication intensive care intensive care unit investigated large cohort lower risk Mortality multicentre observational study outcome Patient patients hospitalized patients with COVID-19 point estimate point estimates Primary outcome Probability receipt risk of death SARS-CoV-2 secondary outcome severe coronavirus disease significant interaction Spain systemic inflammation therapy Tocilizumab Weighting while with COVID-19
[DOI] 10.1016/j.cmi.2020.09.021 PMC 바로가기 [Article Type] Multicenter Study

Characteristics and clinical outcomes of COVID-19 patients in an underserved-inner city population: A single tertiary center cohort

서비스가 부족한 도심 인구에서 COVID-19 환자의 특성 및 임상 결과: 단일 3차 센터 코호트

Article

Published on 2021-01-012022-09-11
Journal: Journal of medical virology [Category] SARS, 바이오마커, 진단, 치료제,

[키워드] 95% CI 95% confidence interval African American age association Asthma baseline Biomarker Biomarkers Characteristics Clinical outcome clinical outcomes Cohort Comorbidities Continuous renal replacement therapy COPD coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 patient CRP CRP level CRP levels CRRT Data collection death demographic Descriptive statistics determine deviation diabetes Diabetes Mellitus disease severity female frequencies Hemodialysis higher risk hospitalized patient hospitalized patients hypertension independent risk factor Infection information inner city hospital Inpatient Laboratory mechanical ventilation Mortality multivariate logistic regression occurred Odds ratio Older age outcomes Patient renal required Requirement retrospective risk factor Risk factors significantly single-center study The United States Treatment United States urban area Vasopressor vasopressors were used with COVID-19
[DOI] 10.1002/jmv.26252 PMC 바로가기 [Article Type] Article

The Systematic Effect of Mesenchymal Stem Cell Therapy in Critical COVID-19 Patients: A Prospective Double Controlled Trial

중증 코로나19 환자에서 중간엽 줄기세포 치료의 체계적인 효과: 전향적 이중 대조 시험

Controlled Clinical Trial

Published on 2021-01-012022-09-11
Journal: Cell transplantation [Category] 유전자 메커니즘, 임상,

[키워드] Analysis anti-inflammatory cytokine anti-inflammatory cytokines Apoptosis Biochemical parameters CD16 CD19 CD3 CD4 CD45 CD56 CD8 Cell cellular chemokines clinical manifestation clinical manifestations clinical trial Controlled COVID-19 COVID-19 patient COVID-19 patients Critical critical cases Critically ill critically ill COVID-19 patients critically ill patients CRP level CRP levels cytokine Cytokine storm Cytokines demonstrated died dose Effect evaluate evaluated fibrinogen group groups growth growth factor Growth factors HLA-DR IFNγ IL-10 IL-12 IL-13 IL-17A IL-1ra IL-2 IL-6 immunomodulatory effect immunomodulatory effects intravenously investigated KGF lymphocyte Lymphocyte subsets marker matrix metalloproteinases mechanism of action mesenchymal stem cell Mesenchymal stem cells moderate MSC MSCs Neutrophils NGF overall mortality Patient positive proinflammatory proinflammatory cytokines Prospective reducing mortality separated Serum ferritin significantly statistical STEM stem cell TGF-β the cytokine storm therapy tissue regeneration treated Treatment VEGF
[DOI] 10.1177/09636897211024942 PMC 바로가기 [Article Type] Controlled Clinical Trial

Influence of aluminum salts on COVID-19 infected patients

COVID-19 감염 환자에 대한 알루미늄 염의 영향

Observational Study

Published on 2020-12-172022-09-10
Journal: Turkish Journal of Medical Sciences [Category] MERS, SARS, 임상, 치료제,

[키워드] addition alum aluminum aluminum salts Analysis Antiviral Chain Reaction clinical Clinical findings Comorbidity Control control group Coronavirus (COVID-19) COVID-19 COVID-19 infected patient COVID-19 infected patients CRP level CRP levels diagnosed discharge drop Effect examined Follow-up group Hospital stay Hospitalization include infected cases infected patients Infectious disease influence intake intensive care Laboratory parameters Lactate lactate dehydrogenase LDH material mechanical ventilation not achieved oral intake pandemic patients PCR performed Pneumonia polymerase chain polymerase chain reaction procalcitonin procalcitonin level radiological Recovery time recovery times Result retrospective cohort study salt salts Side effect Side effects significantly significantly shorter survival Symptom Symptoms the patient Toxicity Treatment treatment group Treatment protocol treatment protocols two group two groups
[DOI] 10.3906/sag-2009-140 PMC 바로가기 [Article Type] Observational Study

IgA2 Antibodies against SARS-CoV-2 Correlate with NET Formation and Fatal Outcome in Severely Diseased COVID-19 Patients

SARS-CoV-2에 대한 IgA2 항체는 중증 COVID-19 환자의 NET 형성 및 치명적인 결과와 상관 관계가 있습니다

Communication

Published on 2020-12-122022-09-11
Journal: Cells [Category] MERS, SARS, 바이오마커, 진단,

[키워드] activate acute respiratory syndrome acute respiratory syndrome coronavirus Adaptive immune response anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibody antibody level antibody levels C-reactive protein C-reactive protein (CRP characterized circulating contribute Control coronavirus correlated COVID-19 CRP level CRP levels extracellular DNA Formation Hospitalization Host ICU IgA IgA2 IgG response IgG responses Immune cell immune cells induce Infection Inflammation intensive care intensive care unit leads less marker mild symptoms moderate moderate symptoms NET neutrophil Neutrophil extracellular trap neutrophil extracellular trap (NET) organ injury outcome Patient patient groups patients plasma sample plasma samples respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike protein SARS-CoV-2-infected patient SARS-CoV-2-infected patients SARS-CoV-2-specific IgG severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease severe SARS severe SARS-CoV-2 specific antibodies Spike protein Symptom the strongest These data TRAP were measured while
[DOI] 10.3390/cells9122676 PMC 바로가기 [Article Type] Communication