Natural history and cycle threshold values analysis of COVID-19 in Xiamen City, ChinaResearch article Published on 2022-09-012022-10-05 Journal: Infectious Disease Modelling [Category] 변종, 치료기술, [키워드] age aggregation Analysis analyzed average calculate calculated China city COVID-19 cycle threshold Cycle threshold value delta variant detection rate difference effective Epidemic Gender Generation time Genes greater IMPROVE Incubation period intergenerational Measures median natural history objective outbreak parameter positive Reproduction number Result statistically Transmission Xiamen [DOI] 10.1016/j.idm.2022.07.007 [Article Type] Research article
Clinical characteristics and treatment outcomes of SARS-CoV-2 delta variant outbreak, Pingtung, Taiwan, June 2021Article Published on 2022-09-012022-11-15 Journal: Journal of the Formosan Medical Association = Taiw [Category] SARS, 변종, 치료제, [키워드] antiviral agent Antiviral agents Aspartate aminotransferase AST Characteristics clinical Clinical characteristics Coronavirus disease 2019 cough COVID-19 cycle threshold defined Delta delta variant demonstrated Diagnosis disease evaluated ferritin Fever headache hospital Infection lactate dehydrogenase LDH mechanical ventilation median Mortality occurred outbreak Patient Pingtung Pneumonia polymerase chain real-time reverse transcriptase repeated risk factor RT-PCR SARS-CoV-2 SARS-CoV-2 delta SARS-COV-2 infection serum Symptom symptomatic Taiwan Treatment Treatment outcome Two patient variant viral shedding [DOI] 10.1016/j.jfma.2022.01.008 PMC 바로가기
Performance evaluation of antigen detection rapid diagnostic test (Ag-RDT) for COVID-19 diagnosis in a primary healthcare center during the Shanghai COVID-19 quarantine periodArticle Published on 2022-09-012022-11-15 Journal: Virology Journal [Category] SARS, 치료기술, [키워드] Ag-RDT Antigen antigen detection Antigen rapid diagnostic test (Ag-RDT) Asymptomatic Asymptomatic COVID-19 average conducted Coronavirus disease 2019 COVID-19 COVID-19 diagnosis cycle threshold Department diagnosis of SARS-CoV-2 Emergency enrolled evaluate healthcare Inconclusive individual Infection N gene ORF1ab ORF1ab gene Patient care performance quarantine Rapid Rapid diagnostic test reliability RT-PCR SARS-CoV-2 SARS-COV-2 infection screened sensitivity Shanghai significantly higher specificity was performed [DOI] 10.1186/s12985-022-01871-6 PMC 바로가기
Harmonization of SARS-CoV-2 reverse transcription quantitative PCR tests to the first WHO international standard for SARS-CoV-2 RNASARS-CoV-2 RNA에 대한 최초의 WHO 국제 표준에 SARS-CoV-2 역전사 정량 PCR 테스트의 조화Article Published on 2022-09-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, [키워드] 95% CI 95% confidence interval Analysis assays association calibration Cepheid clinical samples comparable confidence Ct value Ct values cycle cycle threshold Emergency use evaluate Generalizability generate greater harmonization IMPROVE International international standard interquartile range interval IQR log mean difference median nucleocapsid platform positive quantitation Quantitative quantitative PCR Range Regression reverse transcription RT-qPCR RT-qPCRs SARS-CoV-2 SARS-CoV-2 RNA Standard target targets the mean the WHO threshold upper respiratory viral burden was tested WHO [DOI] 10.1016/j.jcv.2022.105242 PMC 바로가기 [Article Type] Article
Comparison between nucleic acid amplification tests, antigen immunofluorescence assay, and in vitro infectivity in SARS-CoV-2 diagnosisArticle Published on 2022-09-012022-11-16 Journal: Brazilian journal of microbiology : [publication o [Category] COVID19(2023년), SARS, 치료기술, [키워드] amplification analyzed Antigen antigen test Cell Concordance correlated cycle threshold Diagnosis functional greater immunofluorescence assay in vitro increased risk infect Infection initial Laboratory NAAT Nasopharyngeal swab nucleic acid amplification nucleic acid amplification test POCT point-of-care positive Rapid test response SARS-CoV-2 SARS-CoV-2 detection specimen Swab tested viral load quantification virus transmission [DOI] 10.1007/s42770-022-00758-6 PMC 바로가기
Assessing severe acute respiratory syndrome coronavirus 2 infectivity by reverse-transcription polymerase chain reaction: A systematic review and meta-analysisArticle Published on 2022-09-012022-11-15 Journal: Reviews in Medical Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% confidence interval Accuracy acute respiratory syndrome Assessing Cell Cell culture cell culture system clinical heterogeneity coronavirus cycle threshold determine diagnostic estimate Evidence Genome heterogeneity indicate infectivity Infectivity limitation log Logistic regression Major Meta-analysis performed polymerase chain Positive predictive value PPV Probability protocol ranged real-time polymerase chain reaction reference test respiratory sample Respiratory samples RT-PCR SARS-CoV-2 SARS-CoV-2 RNA detection searched specificity statistical subgroup symptom onset systematic review Viral RNA virus isolation [DOI] 10.1002/rmv.2342 PMC 바로가기
Efficacy and safety of camostat mesylate in early COVID-19 disease in an ambulatory setting: a randomized placebo-controlled phase II trialClinical Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] 95% confidence interval adverse event Analysis antiviral drug assigned asymptomatic patient camostat Camostat mesylate Clinical improvement conducted Confirmed COVID-19 infection COVID-19 COVID-19 disease Cox regression cycle threshold distribution early phase effective Efficacy Efficacy and safety Frequency hazard ratio nasopharyngeal viral load Neutralizing antibodies Neutralizing antibody titer participant performed Placebo placebo group placebo-controlled protocol Randomized Randomized controlled trial Randomly receive Safety SARS-CoV-2 symptomatic treat Treatment Trial two groups [DOI] 10.1016/j.ijid.2022.06.054 PMC 바로가기 [Article Type] Clinical Trial
The effect of ivermectin on the viral load and culture viability in early treatment of nonhospitalized patients with mild COVID-19 – a double-blind, randomized placebo-controlled trialRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 신약개발, 임상, 치료법, 치료제, [키워드] 95% confidence interval Anti-SARS-CoV-2 Activity antiparasitic antiviral properties COVID-19 Culture cultures cycle threshold double-blind double-blinded early treatment Endpoint evaluated Infectivity Infectivity duration Ivermectin ivermectin group less Mild multivariable logistic regression Nasopharyngeal swab negative test Odds ratio Patient patients with COVID-19 per-protocol Placebo positive primary endpoint Primary outcome randomized placebo-controlled trial reached receiving recruitment reduce reduction reflected SARS-CoV-2 screened supported the placebo group Transmission Trial viability viral cultures Viral cultures. Viral load was obtained [DOI] 10.1016/j.ijid.2022.07.003 PMC 바로가기 [Article Type] Randomized Controlled Trial
Agreement Between SARS-CoV-2 PCR Test Results Using Nasopharyngeal and Mid-Turbinate Specimens Among Asymptomatic Working-Age AdultsArticle Published on 2022-09-012022-11-15 Journal: Journal of occupational and environmental medicine [Category] COVID19(2023년), SARS, 치료기술, [키워드] agreement Asymptomatic COVID-19 cycle threshold Cycle threshold value decrease detect determine evaluated Infection initial nasopharyngeal PCR PCR testing positive positive result positive test result Qualitative reached reduced repeated Result risk SARS-COV-2 infection SARS-CoV-2 PCR specimen Swab Test Viral load [DOI] 10.1097/JOM.0000000000002620 PMC 바로가기
Quantitative analysis of RT-PCR test results for SARS-CoV-2 diagnostics across Poland during COVID-19 pandemic: Comparison between early stage and major pandemic waves in 2020 and 2021 with reference to SARS-CoV-2 variantsArticle Published on 2022-09-012022-11-15 Journal: Advances in medical sciences [Category] SARS, 변종, 진단, 치료기술, [키워드] 95% confidence interval affected age amplification Analysis analysis of variance analyzed Bonferroni correction COVID-19 COVID-19 case cycle threshold diagnostic diagnostics difference displaying early stage Epidemiology exhibited First wave greater groups inaccuracy limit of detection molecular testing nucleic acid amplification test pandemic Patient patients Poland polymerase chain positive result positive test result ranged recorded reverse transcription risk RT-PCR RT-PCR test SARS-CoV-2 SARS-CoV-2 positive RT-PCR SARS-CoV-2 variant SARS-CoV-2 virus single center tested variant virus were used younger patient [DOI] 10.1016/j.advms.2022.09.002 PMC 바로가기