Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples Research Published on 2022-02-072022-10-05 Journal: Nature biomedical engineering [Category] COVID19(2023년), SARS, 바이오마커, 치료기술, [키워드] biofluid biofluids Concentration controls Cycle threshold value DNA double-stranded flexible ions less molecular nasopharyngeal sample nucleic acid nucleic acid amplification patients with COVID-19 probe Proteins Rapid RNA extraction SARS-CoV-2 SARS-CoV-2 RNA single-stranded DNA small molecule thrombin [DOI] 10.1038/s41551-021-00833-7 [Article Type] Research
Prolonged SARS-CoV-2 infection following rituximab treatment: clinical course and response to therapeutic interventions correlated with quantitative viral cultures and cycle threshold values리툭시 맙 치료 후 연장 된 SARS-COV-2 감염 : 정량적 바이러스 배양 및 사이클 임계 값과 관련된 치료 중재에 대한 임상 과정 및 반응Case Reports Published on 2022-02-052022-09-01 Journal: Antimicrobial Resistance and Infection Control [Category] COVID19(2023년), Fulltext, MERS, SARS, 진단, 치료기술, [키워드] absence acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration antiviral therapies antiviral therapy approach B-cells clearance Clinical course Clinical parameters complex coronavirus correlated COVID-19 patient COVID-19 patients COVID-19 vaccination Cycle threshold value detection diagnostics highlight Immunocompromised patient Immunosuppressed Immunosuppression implication infection control Infection prevention maintenance nasopharyngeal swabs Oropharyngeal oropharyngeal or nasopharyngeal swabs parameters Patient PCR cycle Prevention and control Prolonged prolonged viral shedding Quantitative question raise recent respiratory reverse transcriptase risk factor RNA RT-PCR SARS-CoV-2 SARS-COV-2 infection Sequencing severe acute respiratory syndrome Coronavirus Steroids suggested supplementary material Therapeutic approach therapeutic intervention Therapeutics threshold vaccination Viral viral clearance viral culture viral shedding virus whole genome Whole genome sequencing [DOI] 10.1186/s13756-022-01067-1 PMC 바로가기 [Article Type] Case Reports
Monitored Implementation of COVID-19 Rapid Antigen Screening at Taxi Ranks in Johannesburg, South AfricaArticle Published on 2022-02-032022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] Ag-RDT Ag-RDTs Antigen Community-based testing COVID-19 COVID-19 diagnosis COVID-19 testing Cycle threshold value Differentiated care Digital eligible enrolled False negative Follow-up Health high risk investigated member moderate over participant Participants PCR testing positive questionnaire Randomly RANK Rapid Rapid diagnostic test risk Risk factors SARS-CoV-2 screened Screening selected South Africa subset Support Symptom taxi rank tested Testing viral loads [DOI] 10.3390/diagnostics12020402 PMC 바로가기 [Article Type] Article
Comparative Effectiveness of Coronavirus Vaccine in Preventing Breakthrough Infections among Vaccinated Persons Infected with Delta and Alpha Variants델타 및 알파 변이체에 감염된 백신 접종자의 돌발 감염 예방에 대한 코로나바이러스 백신의 비교 효과Research Published on 2022-02-012022-09-10 Journal: Emerging Infectious Diseases [Category] COVID19(2023년), MERS, SARS, 변종, [키워드] acute respiratory syndrome adjusted age Alpha Alpha variant Breakthrough infection breakthrough infections Comparative coronavirus coronavirus disease coronavirus variants COVID-19 Cycle threshold value Delta delta variant Diagnosis Effectiveness Infection Logistic regression mean difference mRNA vaccine mRNA vaccines Odds ratio Patient PCR cycle PCR-positive Person Portugal Preventing preventing infection reported respiratory respiratory infections SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 Sex significantly higher threshold value used data vaccination Vaccination Status Vaccine vaccine-preventable diseases variant Viral Viral load viruses zoonoses [DOI] 10.3201/eid2802.211789 PMC 바로가기 [Article Type] Research
Assessment of SARS-CoV-2 viral loads in combined nasal-and-throat swabs collected from COVID-19 individuals under the Universal Community Testing Programme in Hong Kong홍콩의 유니버설 커뮤니티 테스트 프로그램에 따라 COVID-19 개인으로부터 수집된 코와 인후 결합 면봉에서 SARS-CoV-2 바이러스 부하 평가Article Published on 2022-02-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition assessment Asymptomatic individuals choice CNTS collected Combined Combined nasal-and-throat swabs comparable conducted COVID-19 Cycle threshold value demonstrated diagnosis of SARS-CoV-2 healthcare worker Healthcare workers Hong Kong individual individuals induce invasive lack less lower risk RT-PCR SARS-CoV-2 SARS-CoV-2 viral load specimen Swab Symptom Testing throat swabs Universal Universal Community Testing Programme. Viral load viral loads [DOI] 10.1016/j.jviromet.2021.114396 PMC 바로가기 [Article Type] Article
Clinical assessment of SARS-CoV-2 antigen rapid detection compared with RT-PCR assay for emerging variants at a high-throughput community testing site in Taiwan대만의 고처리량 커뮤니티 테스트 사이트에서 새로운 변이체에 대한 RT-PCR 분석과 비교한 SARS-CoV-2 항원 신속 검출의 임상 평가Article Published on 2022-02-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Antigen B.1.1.7 B.1.1.7 lineage Chain Reaction Characteristics clinical assessment Community community transmission condition confidence interval coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 Cycle threshold value Cycle threshold values facilitate flare help lateral flow Lineage New Taipei City pandemic polymerase chain polymerase chain reaction positive Prevent Rapid rapid antigen test Rapid diagnostic test Rapid test reverse transcription reverse transcription polymerase chain reaction RT-PCR RT-PCR assay SARS-CoV-2 SARS-CoV-2 antigen sensitivity Sensitivity and specificity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus specimen subject subpopulation Taiwan Test tested the SARS-CoV-2 Transcription turnaround time variant was used [DOI] 10.1016/j.ijid.2021.11.034 PMC 바로가기 [Article Type] Article
Prospective evaluation of the point-of-care use of a rapid antigenic SARS-CoV-2 immunochromatographic test in a paediatric emergency departmentOriginal Article Published on 2022-01-202022-10-04 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), MERS, SARS, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome AgPOCT Antigen Antigen point-of-care test antigenic Asymptomatic children coronavirus coronavirus disease COVID-19 Cycle threshold value detect diagnosing diagnosis of SARS-CoV-2 Diagnosis test enrolled evaluate France groups Hospitalization immunochromatographic immunochromatographic test Infection nasopharyngeal negative sample objective paediatric PCR POCT point-of-care positive positive sample presenting Prospective Quantitative reference standard respiratory symptom Result reverse transcription RT-qPCR SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity significantly lower symptomatic symptomatic and asymptomatic tested university with COVID-19 [DOI] 10.1016/j.cmi.2021.12.019 PMC 바로가기 [Article Type] Original Article
Reduced amplification efficiency of the RNA-dependent-RNA-polymerase target enables tracking of the Delta SARS-CoV-2 variant using routine diagnostic testsArticle Published on 2022-01-182022-10-04 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] 2019-nCoV amplification AUC, area under the curve can be used Cape conserved COVID-19 Cycle threshold value Delta delta variant diagnostic diagnostic test E, Envelope Efficiency GISAID, Global Initiative on Sharing All Influenza Data GTF, Gene Target Failure investigated IQR, interquartile range N, nucleocapsid NGS-SA, Network for Genomic Surveillance South Africa NHLS, National Health Laboratory Service Non-synonymous mutation Patient Prevalence RΔE, difference between the Ct values for RdRp and E-gene targets RdRp gene RdRp, RNA-dependent-RNA-polymerase reduced routine RT-PCR RT-PCR, reverse transcriptase polymerase chain reaction S, spike SARS-CoV-2 SARS-CoV-2 surveillance SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 Sequencing significant increase South Africa subset Surveillance tested the median the SARS-CoV-2 variants VOCs, Variants of Concern WGS, Whole Genome Sequencing while whole genome Whole genome sequencing [DOI] 10.1016/j.jviromet.2022.114471 PMC 바로가기 [Article Type] Article
Trajectory of Viral RNA Load Among Persons With Incident SARS-CoV-2 G614 Infection (Wuhan Strain) in Association With COVID-19 Symptom Onset and SeverityCOVID-19 증상 발병 및 중증도와 관련하여 SARS-CoV-2 G614 감염(우한 균주)이 발생한 사람의 바이러스 RNA 부하 궤적Randomized Controlled Trial Published on 2022-01-102022-09-10 Journal: JAMA Network Open [Category] 변종, 임상, 진단, 치료기술, [키워드] association Asymptomatic baseline Characteristics characterized clinical trial Clinical trial design clinical trials Cohort cohort study collected conducted correlated COVID-19 COVID-19 symptom Ct value cycle threshold Cycle threshold value Data analysis enrolled exposure finding Follow-up followed by G614 variant Importance incident individual Infection infections initial laboratory-confirmed SARS-CoV-2 infection linear load measure median median age men Mild symptom mild symptoms mixed-effects model moderate molecular natural history objective occurred Onset pandemic participant peak Person Point positive positive swab prospective cohort study public health referred to Relevance Result RNA SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA detection SARS-CoV-2 viral SARS-CoV-2 viral load SARS-CoV-2 viral RNA SARS-CoV-2–positive sequenced sample setting severe symptom severity shedding Spread statistical model strain Swab swab sample swab samples Symptom symptom onset symptom severity symptomatic tested the patient the SARS-CoV-2 therapeutic These data trajectory Viral viral lineage Viral load Viral RNA viral shedding viral variant virus were used with COVID-19 women Wuhan Wuhan strain [DOI] 10.1001/jamanetworkopen.2021.42796 PMC 바로가기 [Article Type] Randomized Controlled Trial
SARS-CoV2 infection in symptomatic patients: interest of serological tests and predictors of mortality: experience of DR Congo증상 환자의 SARS-COV2 감염 : 혈청 검사의 관심 및 사망률 예측 자 : DR Congo의 경험Research Article Published on 2022-01-042022-09-01 Journal: BMC Infectious Diseases [Category] SARS, 진단, 치료기술, [키워드] Admission approach ARDS best clinical Clinical stage Clinical stages Combination Concordance COVID-19 COVID-19 patient COVID-19 patients Cox regression Cycle threshold value death diagnostic Dyspnea evaluate expressed Factor greater hospital identify IgG IgM IgM/IgG increase in increased the risk Kappa coefficient Mortality Patient patients performed positive predict predictor recorded referred to Result RT-PCR SARS- CoV-2 SARS-CoV2 infection serological test Serological tests shown significantly Stage Support symptomatic Symptomatic patients treat university university hospital Viral Viral load were used WHO WHO classification [DOI] 10.1186/s12879-021-07003-9 PMC 바로가기 [Article Type] Research Article