Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences인도-아프리카 서열을 기반으로 하는 EDIII-NS1 컨센서스 디자인을 암호화하는 새로운 뎅기열 DNA 백신의 면역 프로필 및 반응Article Published on 2022-05-042022-09-11 Journal: Molecular therapy : the journal of the American So [Category] MERS, 변종, 진단, [키워드] antibody Antibody-dependent enhancement Antigen antigens clinical isolates coding sequence Consensus consensus sequence conserved COVID-19 pandemic Dengue dengue surveillance. dengue virus DENV-2 DNA DNA vaccine domain domain III EDIII domain emerging viruses envelope protein epitope Epitopes expand Genotype highlight IgG1 immune immune response immunogenic Immunoglobulin India Indo-African interferon isolate mice neutralizing antibody non-structural protein NS1 protein passive transfer protein expression response sequence Sequencing sera serotype serotype-specific staining Stand Structural analysis Surveillance T cell T cell responses transfer translation vaccination Vaccine vaccine candidate Vaccine design Viral Viral variants virulent viruses whole genome Whole genome sequencing [DOI] 10.1016/j.ymthe.2022.01.013 PMC 바로가기 [Article Type] Article
Assessment of the clinical and laboratorial profile of patients with obesity and asymptomatic COVID-19 undergoing bariatric surgery in Brazil브라질에서 비만 수술을 받은 무증상 COVID-19 환자의 임상 및 실험실 프로필 평가Article Published on 2022-04-012022-09-11 Journal: Obesity surgery [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age assessment Asymptomatic case Asymptomatic cases Asymptomatic COVID-19 Bariatric surgery BMI body mass body mass index Brazil C-reactive protein Case series Chain Reaction collected Complication Coronavirus-2 COVID19 demographic characteristics Dengue dengue virus diabete diabetes Diagnosis disease severity elapsed ferritin FIVE Hospital stay hypertension IgG incidence inflammatory markers Laboratory lymphocyte Lymphocytes marker Micronutrient micronutrients obesity operation Patient patients with obesity polymerase chain reaction positive positive RT-PCR postoperative Postoperative Complications Preoperative period previous diagnosis reported reported symptoms RT-PCR serology serum Serum level serum levels Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus Sleeve Sleeve gastrectomy study period surgery tested the mean Vitamin D without symptom women Zinc [DOI] 10.1007/s11695-022-05891-7 PMC 바로가기 [Article Type] Article
Perspective on the Use of Innovative Surveillance Strategies Implemented for COVID-19 to Prevent Mosquito-Borne Disease Emergence in French Polynesia프렌치 폴리네시아에서 모기 매개 질병 발생을 예방하기 위해 COVID-19에 대해 구현된 혁신적인 감시 전략의 사용에 대한 관점Article Published on 2022-02-242022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 arbovirus Arboviruses circulation coronavirus COVID-19 Dengue dengue virus emergence Epidemiology French French Polynesia Infection International interruption limit Local lockdown measure Pathogens Polynesia Prevent SARS-CoV-2 SARS-CoV-2 RT-PCR serotype severe acute respiratory syndrome Coronavirus Strategy Surveillance Transmission Travelers virus spread viruses [DOI] 10.3390/v14030460 PMC 바로가기 [Article Type] Article
Evolution of Viral Pathogens Follows a Linear OrderResearch Article Published on 2022-02-022022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, COVID19(2023년), SARS, 신종인플루엔자, [키워드] acute respiratory syndrome addition Amino acid Analysis contribute coronavirus coronavirus disease COVID-19 dengue virus determine distribution Evidence Evolution H1N1 H3N2 HCoV-229E HCoV-NL63 HCoV-OC43 Infectious disease influenza A linear linear order MERS MERS-CoV Microbiology Middle East outbreak Outbreaks predict random reveal SARS-CoV SARS-CoV-2 serotype shown subsequent syndrome triggering Vaccine variants of concern viral family viral genome viral mutation viral pathogen virus Zaire Zika [DOI] 10.1128/spectrum.01655-21 PMC 바로가기 [Article Type] Research Article
The Usefulness of Peripheral Blood Cell Counts to Distinguish COVID-19 from Dengue during Acute InfectionArticle Published on 2022-01-302022-10-29 Journal: Tropical Medicine and Infectious Disease [Category] COVID-19, [키워드] 95% CI Accuracy acute phase adjusted Analysis AUC calculate count COVID-19 Dengue dengue virus disease evaluated infected with SARS-CoV-2 Infection laboratory feature Logistic regression Lymphocyte count neutrophil neutrophil–lymphocyte ratio neutrophil–lymphocyte ratio Neutrophils NLR Patient peripheral peripheral blood cell peripheral blood cells count neutrophils Platelet Platelets predicted Predictive predictors Probability regions ROC Curve Sensitivity and specificity similarity symptom onset Treatment tropical were used with COVID-19 [DOI] 10.3390/tropicalmed7020020 PMC 바로가기 [Article Type] Article
A Journey into the Clinical Relevance of Heme Oxygenase 1 for Human Inflammatory Disease and Viral Clearance: Why Does It Matter on the COVID-19 Scene?Review Published on 2022-01-292022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] activating acute respiratory syndrome Anti-inflammatory Antioxidative antiviral property caused cellular homeostasis characterized clinical clinical manifestation complications coronavirus coronavirus disease COVID-19 Degradation dengue virus Ebola virus functions heme heme oxygenase 1 Hepatitis virus Human Human immunodeficiency virus IFN Infectious disease Inflammatory inflammatory disease influenza A virus Injury involved kidney lung matter nervous system oxidative Oxygenase pathway protective role rate-limiting enzyme Relevance Replication Research Respiratory failure respiratory syncytial virus SARS-CoV-2 Symptom systemic hyperinflammation the interferon viral infection viral infections Zika virus [DOI] 10.3390/antiox11020276 PMC 바로가기 [Article Type] Review
Evidence of Coinfections between SARS-CoV-2 and Select Arboviruses in Guerrero, Mexico, 2020-2021멕시코 게레로, 2020-2021년 SARS-CoV-2와 일부 아르보바이러스 간의 공동 감염 증거Article Published on 2022-01-242022-09-12 Journal: The American Journal of Tropical Medicine and Hygi [Category] 진단, [키워드] Antigen arbovirus Chikungunya Coinfection dengue virus differential diagnosis Evidence evidence of febrile patient FIVE IgM Infection Laboratory occur Patient patients plaque reduction neutralization Region responsible RNA SARS-CoV-2 SARS-COV-2 infection Serologically Seven study population tested Undetermined virus Zika virus ZIKV [DOI] 10.4269/ajtmh.21-1216 PMC 바로가기 [Article Type] Article
Plant-Derived Recombinant Vaccines against Zoonotic VirusesReview Published on 2022-01-212022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] approach candidate vaccine Chikungunya virus chimeric Crimean–Congo hemorrhagic fever virus current deaths dengue virus disease Diseases Ebola virus effective emerging coronaviruses expression genetic material Hantaviruses Henipaviruses hepatitis E virus HIV Human immunogenic include lack Newcastle virus offer organization plant plant molecular farming Prevent produced Proteins Rabies virus recombinant Recombinant protein recombinant vaccines restrict Safe Spread structural proteins subunit vaccination Vaccine Vaccines viral peptides virion virus virus particles Virus-like particle virus-like particles viruses VLP VLPs West Nile Virus yellow fever virus Zika virus zoonotic zoonotic disease zoonotic influenza Zoonotic viruses [DOI] 10.3390/life12020156 PMC 바로가기 [Article Type] Review
The potential of COVID-19 patients’ sera to cause antibody-dependent enhancement of infection and IL-6 productionCOVID-19 환자의 혈청의 잠재력은 감염 및 IL-6 생산의 항체 의존적 향상을 유발합니다.Article Published on 2021-12-092022-09-01 Journal: Scientific Reports [Category] SARS, 진단, 치료기술, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ADE Antibody-dependent enhancement cell line clone cloned coronavirus COVID-19 demonstrated dengue virus evaluate host cell host cells IL-6 immortalized Infection infection with SARS-CoV-2 infections initiated myeloid cell neutralizing antibody other coronavirus other coronaviruses productivity respiratory resulting SARS-CoV-2 SARS-COV-2 infection screened sera severe acute respiratory syndrome Coronavirus severe COVID-19 patient severe COVID-19 patients stimulate susceptibility TMPRSS2 vaccination Vaccine development vaccine trial virus infections [DOI] 10.1038/s41598-021-03273-0 PMC 바로가기 [Article Type] Article
Gravity-Driven Microfluidic Siphons: Fluidic Characterization and Application to Quantitative Immunoassays중력 중심 미세 유체 사이펀 : 양적 면역 분석에 대한 유체 특성 및 적용Article Published on 2021-12-022022-10-27 Journal: ACS Sensors [Category] Coronavirus, 진단, 치료기술, [키워드] a glass amplified anti-SARS-CoV-2 IgG antigen detection application approach automated biological sample biological samples biosensor Capillaries characterization dead volume demonstrated Dengue Dengue fever dengue NS1 dengue virus dependent on Device Diagnosis diagnostic Dipstick ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay fiber glass Glass fiber gravity IgM immunoassay immunoassays immunochromatographic intrinsically lab lateral flow membrane microfluidic operation overlap POC point-of-care porous porous membrane portable ELISA public health quantitation Quantitative reagent sandwich ELISA sequence serotype serotype-specific serum samples siphon smartphone diagnostics strip unique [DOI] 10.1021/acssensors.1c01524 PMC 바로가기 [Article Type] Article