Immunogenicity and Safety of the COVID-19 Vaccines Compared With Control in Healthy Adults: A Qualitative and Systematic ReviewRandomized Controlled Trial Published on 2022-05-012022-10-04 Journal: Value in health : the journal of the International [Category] 비임상, 유전자 메커니즘, 임상, [키워드] 6 hour acute respiratory syndrome adverse event adverse events all-cause mortality antibody conducted Control control arm control group Controlled trial coronavirus COVID-19 COVID-19 vaccine death disease dose elicited emergence evaluate examined fatigue females Fever for inclusion geometric mean titer GMT GMTs group headache highest immune response immunogenicity Immunoglobulin Infection local reaction Mild mRNA-1273 neutralizing antibody Pain pandemic Placebo postvaccination profiles Qualitative ranged reaction reported retrieved review Safety seroconversion rates severe adverse event subject systematic review the healthy tolerable vaccination Vaccine Vaccines while [DOI] 10.1016/j.jval.2021.09.003 PMC 바로가기 [Article Type] Randomized Controlled Trial
The Emergence of Omicron: Challenging Times Are Here Again!오미크론의 출현: 도전적인 시대가 다시 도래했습니다!Review Published on 2022-05-012022-09-11 Journal: Indian journal of pediatrics [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha average Beta booster vaccinations Care caused children consequence country COVID COVID-19 death disease doubling driving Effect emergence equity expected Government Health Health care Hospitalization imperative India indirect effect indirect effects Infection lockdowns Mental Mild Mutation neglect notable offer omicron Omicron variant on children other diseases other variants phylogenetically physical PROTECT reported severe disease Spread Third wave time Travel vaccination Vaccinations Vaccine variant variant of concern (VOC) variants VoC worsened [DOI] 10.1007/s12098-022-04077-4 PMC 바로가기 [Article Type] Review
Epistasis at the SARS-CoV-2 Receptor-Binding Domain Interface and the Propitiously Boring Implications for Vaccine EscapeSARS-CoV-2 수용체 결합 도메인 인터페이스에서의 상위성과 백신 탈출에 대한 지루한 의미Article Published on 2022-04-262022-09-11 Journal: mBio [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody appear approach binding site closely resemble Complete coronavirus COVID-19 pandemic Delta delta variant destabilize dominance Effect Efficacy emergence epistasis escape escape mutants escape mutation Evolution Gamma Gamma variant host receptor include Interaction interface majority multiple mutation mutants Mutation mutations neutralizing antibody omicron Omicron variant Omicron variants overlap Protein protein structure protein structure modeling. RBD RBD mutation RBD mutations RBD-ACE2 Receptor-binding domain reduce reduced repertoire respiratory resulting risk Rosetta SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 virus severe acute respiratory syndrome Coronavirus single mutant Spike protein the RBD the receptor-binding domain the SARS-CoV-2 the spike protein unlikely Vaccine vaccine efficacy Vaccines variant variants variants of SARS-CoV-2 virus wild type wild-type SARS-CoV-2 [DOI] 10.1128/mbio.00135-22 PMC 바로가기 [Article Type] Article
Implementation of a Streamlined SARS-CoV-2 Whole-Genome Sequencing Assay for Expeditious Surveillance during the Emergence of the Omicron Variant오미크론 변이체 출현 시 신속한 감시를 위한 간소화된 SARS-CoV-2 전체 게놈 시퀀싱 분석의 구현Article Published on 2022-04-202022-09-11 Journal: Journal of Clinical Microbiology [Category] COVID19(2023년), SARS, 변종, [키워드] Abstract emergence genomic genomic sequencing omicron SARS-CoV-2 variants variants of concern [DOI] 10.1128/jcm.02569-21 PMC 바로가기 [Article Type] Article
Emergence and phenotypic characterization of the global SARS-CoV-2 C.1.2 lineageArticle Published on 2022-04-082022-10-04 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, [키워드] Beta change convalescent D614G Delta disease severity Donor Efficacy emergence Epidemiology functional genomic Health authority identified variant include individual infected individuals Infection initial Like Lineage neutralisation neutralization offer phenotypic plasma Prevalence reduced SARS-CoV-2 SARS-CoV-2 variant sensitivity significantly South Africa Spread Surveillance the spike protein Transmissibility Vaccine vaccinee variants of interest viral infection virus [DOI] 10.1038/s41467-022-29579-9 PMC 바로가기 [Article Type] Article
Early Emergence Phase of SARS-CoV-2 Delta Variant in Florida, US미국 플로리다에서 SARS-CoV-2 델타 변종 초기 출현 단계Article Published on 2022-04-062022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] addition Asia B.1.617.2 benefit causative agent clade contagious COVID-19 Delta delta variant demonstrated dominant lineage early emergence effort emergence Epidemic Epidemiology Europe FIVE Florida genomes genomic Genomic analysis independent India Local MONITOR North America pandemic phase Phylogenetic analysis prevalent Public health responses SARS-CoV-2 Spread subsequent Substitution Support Surveillance Transmission Transmission dynamics understanding variant variants VoC [DOI] 10.3390/v14040766 PMC 바로가기 [Article Type] Article
Evasion of vaccine-induced humoral immunity by emerging sub-variants of SARS-CoV-2SARS-CoV-2의 새로운 하위 변종에 의한 백신 유도 체액 면역 회피Article Published on 2022-04-012022-09-11 Journal: Future Microbiology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] accelerate Beta Beta variant contributed COVID-19 dose Effectiveness Efficacy emergence escape mutant evaluate exhibited genomic global public health highest Humoral immunity Imdevimab immune Immune escape material mRNA vaccine Mu variant mutant mutants neutralization neutralization test Neutralizing activity Neutralizing antibodies no decrease omicron Pfizer/BioNTech Phenotypic analysis Receptor-binding domain retained SARS-CoV-2 SARS-CoV-2 variant selection pressure sera shown strain Strains Surveillance tested the receptor-binding domain vaccination Vaccine vaccine effectiveness were used [DOI] 10.2217/fmb-2022-0025 PMC 바로가기 [Article Type] Article
Emergence of Two Distinct SARS-CoV-2 Gamma Variants and the Rapid Spread of P.1-like-II SARS-CoV-2 during the Second Wave of COVID-19 in Santa Catarina, Southern Brazil브라질 남부 산타 카타리나에서 COVID-19의 두 번째 물결 동안 2개의 고유한 SARS-CoV-2 감마 변이체의 출현과 P.1-like-II SARS-CoV-2의 급속한 확산Article Published on 2022-03-272022-09-11 Journal: Viruses [Category] SARS, 변종, [키워드] affected Beta Brazil Case fatality rate CFR COVID-19 COVID-19 pandemic dispersion emergence evaluate Evidence evidence of Fatality rate Gamma Genome genomic Genomic surveillance highlight increase in Lineage Mortality P.1 pandemic predominant public health systems Rapid SARS-CoV-2 SARS-CoV-2 P.1 variant SARS-CoV-2 transmission SARS-CoV-2 virus second Surveillance the SARS-CoV-2 the SARS-CoV-2 virus Transmission variants Wave [DOI] 10.3390/v14040695 PMC 바로가기 [Article Type] Article
Emergence of the E484K Mutation in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Lineage B.1.1.345 in Upstate New York뉴욕 북부의 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 계통 B.1.1.345에서 E484K 돌연변이의 출현Article Published on 2022-03-092022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis association coronavirus coronavirus 2 E484K E484K mutation emergence epidemiological hospital Lineage lineage B.1.1.345. New York Patient respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus variant [DOI] 10.1093/cid/ciab507 PMC 바로가기 [Article Type] Article
United States Influenza Search Patterns Since the Emergence of COVID-19: Infodemiology StudyOriginal Paper Published on 2022-03-032022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, SARS, [키워드] 95% confidence interval affected affecting average calculated CDC center Control Coronavirus disease 2019 correlation Coverage COVID-19 COVID-19 diagnosis COVID-19 infection COVID-19 pandemic emergence flu Google Google Trends Influenza infodemiology information-seeking limitation media media coverage Modification monitoring objective online health information pattern predicted prevention remained Result retrieved Surveillance Symptom the United State The United States trend United State United States Volume [DOI] 10.2196/32364 PMC 바로가기 [Article Type] Original Paper