Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor
Research Article
[키워드] 3CLpro
Animal coronaviruses
Antiviral compound
antiviral drug
antiviral drugs
Antiviral treatment
cause
caused
cell tropism
contributed
coronavirus
Coronavirus infection
Coronavirus infections
Cross-species transmission
death
disease
Diseases
effective
Efficacy and safety
evaluated
experimental evidence
facilitate
fatal disease
fatality
feature
Feline infectious peritonitis
Fever
full recovery
Health
Host
Human
humans
immune response
Immune-mediated
infect
inflammatory disease
inhibitor
Laboratory
less
lymphopenia
mammalian
measure
Mild
Mutation
other coronavirus
pathogen
Pathogenesis
progression
protease
Protease inhibitor
recombination rate
reduction in
Replication
reported
required
respiratory
resulting
returned
reversal
risk
Significant
T cells
therapeutic
therapeutic efficacy
therapeutic strategy
tissue
Treatment
viable treatment
viral titer
virulence
virulent
virus
virus replication
[DOI] 10.1371/journal.ppat.1005531 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1005531 PMC 바로가기 [Article Type] Research Article