Evaluation of a fully closed real time PCR platform for the detection of SARS-CoV-2 in nasopharyngeal swabs: a pilot study비인두 면봉에서 SARS-CoV-2 검출을 위한 완전 폐쇄형 실시간 PCR 플랫폼 평가: 파일럿 연구Article Published on 2022-08-012022-09-11 Journal: Journal of Clinical Pathology [Category] SARS, 치료기술, [키워드] addition analysed approach clinical follow-up close contact contact with COVID-19 cycle threshold demonstrated develop Diagnosis diagnosis of COVID-19 evaluate FIVE Follow-up gold gold standard infection control initial nasopharyngeal Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nasopharyngeal swabs Patient PCR pilot study platform positive positive result real time retrieved reverse transcriptase reverse transcriptase PCR robust RT-PCR RT-PCR test SARS-CoV-2 SARS-COV-2 infection sensitivity Sensitivity and specificity specificity subset symptomatic patient Symptomatic patients Test tested viral infection with COVID-19 [DOI] 10.1136/jclinpath-2021-207516 PMC 바로가기 [Article Type] Article
Performance and application evaluation of SARS-CoV-2 antigen assaySARS-CoV-2 항원 분석의 성능 및 응용 평가Review Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] Accessibility accumulated acute respiratory syndrome acute respiratory syndrome coronavirus addition alleviate Antigen antigen detection approved Asymptomatic can not Clinical data coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 vaccines diagnoses Diagnosis False positive False positives gold gold standard hospitals increase in Interpretation Laboratory laboratory diagnosis mutant mutant strain Mutant strains Negative predictive value nucleic acid Nucleic acid detection offer performance positive result Practitioner Predictive value Prevalence Probability promote reagent SARS-CoV-2 SARS-CoV-2 antigen SARS-COV-2 infection SARS-CoV-2 nucleic acid sensitivity Sensitivity and specificity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specificity speed the SARS-CoV-2 the WHO trade-off WHO [DOI] 10.1002/jmv.27798 PMC 바로가기 [Article Type] Review
Validation and advantages of using novel RT-qPCR melting curve analysis assays for the identification of SARS-CoV-2 variantsSARS-CoV-2 변이체 식별을 위한 새로운 RT-qPCR 용융 곡선 분석 분석 사용의 검증 및 이점Article Published on 2022-07-292022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] clinical monitoring Cohort complementary Contact tracing diagnosing E484K examined FIVE gold gold standard in viral K417N melting curve analysis Mutation mutations N439K N501Y new virus P681H positive probes quantitative PCR ranged reverse transcription risk stratification RT-qPCR Sample Sanger sequencing SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike glycoprotein SARS-CoV-2 variant sensitivity Sensitivity and specificity sequence significantly specificity spike glycoprotein Spread the SARS-CoV-2 Transcription validation validation cohort variant variants VOCs [DOI] 10.1038/s41598-022-17339-0 PMC 바로가기 [Article Type] Article
Effects of Structured Supervised Exercise Training or Motivational Counseling on Pregnant Women’s Physical Activity Level: FitMum – Randomized Controlled TrialRandomized Controlled Trial Published on 2022-07-202022-10-04 Journal: Journal of Medical Internet Research [Category] 임상, [키워드] 95% CI activity addition adjusted Adverse age Analysis association Attendance average baseline Changing commercial activity tracker complementary Compliance Controlled counseling COVID-19 Digital health doubly labeled water Effect effective evaluate the effect event EXE exercise fitness Garmin gold standard groups Health health outcome healthy hypothese IMPROVE inactive intensity Intervention intervention group investigated IQR Maternal Maternal Health maternity measure median motivation not affect not differ Offering participant performed physical physical activity physical activity questionnaire pregnancies Pregnancy pregnant pregnant women Primary outcome primary outcome analysis randomization Randomized Randomized controlled trial RCT recommendation Registered Safe Serious Adverse Event standard care tracker training was measured was performed women women's health would increase [DOI] 10.2196/37699 PMC 바로가기 [Article Type] Randomized Controlled Trial
Development of a Rapid Live SARS-CoV-2 Neutralization Assay Based on a qPCR ReadoutqPCR 판독을 기반으로 한 Rapid Live SARS-CoV-2 중화 분석의 개발Article Published on 2022-07-202022-09-11 Journal: Journal of Clinical Microbiology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] antibody Antibody-mediated immunity antiviral activity calculate can be used characteristic controls correlation COVID-19 COVID-19 pandemic cross-neutralization demonstrated detect determine determined by development domain ELISA experiments faster generate gold gold standard Immunity Live virus natural infection neutralization Neutralization assay neutralization assays Neutralizing Neutralizing antibodies neutralizing antibody patient sera priority qPCR qRT-PCR Rapid Receptor-binding domain reduce reduction SARS-CoV-2 SARS-CoV-2 neutralizing antibodies SARS-CoV-2 neutralizing antibody SARS-CoV-2 qRT-PCR Sensitivity and specificity sera significantly standard curve surrogate neutralization assay tested vaccination variants Vero E6 Vero E6 cell VERO E6 cells Viral Viral load Viral RNA virus virus isolate Virus neutralization [DOI] 10.1128/jcm.00376-22 PMC 바로가기 [Article Type] Article
Ultra-rapid somatic variant detection via real-time targeted amplicon sequencing Research Published on 2022-07-152022-10-05 Journal: Communications Biology [Category] 바이오마커, 변종, 유전자 메커니즘, 진단, [키워드] Algorithm Amplicon sequencing amplification approach approaches bioinformatics cancer diagnosis clinical trial diagnostic DNA DNA extraction Enrollment gold standard information intraoperative less Molecular marker Mutation protocols reduce sequenced Support surgical time-consuming tissue variant [DOI] 10.1038/s42003-022-03657-6 [Article Type] Research
Evaluation of Bi-Lateral Co-Infections and Antibiotic Resistance Rates among COVID-19 Patients in Lahore, PakistanObservational Study Published on 2022-07-062022-10-05 Journal: Medicina [Category] 임상, [키워드] Acinetobacter antibiotic Antibiotic resistance antibiotic stewardship Bacteria Bacterial bacterial co-infection Bacterial infections carbapenem resistant Enterobacteriaceae Care clinical sample collected Complication conducted coronavirus COVID-19 COVID-19 patient Critically ill cultures diagnosed diagnostic methods diffusion E. coli Enterobacteriaceae Enterococcus Escherichia coli gold standard highest hospital hospital acquired infections. Hospital admission illnesses increase in Infection infections Influenza inhibitory concentration isolate isolates material methicillin morbidity and mortality MRSA National oxygen Patient positive Prevalence protective role Rate resistance Result Risk factors shown Staphylococcus aureus susceptibility tested Treatment viral respiratory [DOI] 10.3390/medicina58070904 PMC 바로가기 [Article Type] Observational Study
CoVITEST: A Fast and Reliable Method to Monitor Anti-SARS-CoV-2 Specific T Cells From Whole BloodCoVITEST: 전혈에서 Anti-SARS-CoV-2 특정 T 세포를 모니터링하는 빠르고 신뢰할 수 있는 방법Article Published on 2022-07-052022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] adjust antibodies Antibody detection automated Blood blood test can be used Cellular immune response cellular immunity cellular response comparable complex convalescent COVID-19 demonstrated determine diagnostic Donor ELISPOT Evidence explained gold gold standard healthy help house humoral immune response humoral immune responses IFN-γ IFN-γ ELISPOT immune protection immune responses Immune status IMPROVE individual less MONITOR pandemic Patient protocol Reinfection SARS-CoV-2 side simple Specific Support T cell T cells Test therapeutic approaches vulnerable patient vulnerable patients weakened immune system [DOI] 10.3389/fimmu.2022.848586 PMC 바로가기 [Article Type] Article
Clinical Performance of Three Commercial SARS-CoV-2 Rapid Antigen Tests for Community-Dwelling Individuals in a Tropical Setting열대 환경에서 커뮤니티 거주 개인을 위한 3가지 상용 SARS-CoV-2 신속 항원 검사의 임상 성능Multicenter Study Published on 2022-07-052022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] analytical sensitivity Antigen antigen test biosensor carried Certest clinical clinical performance. Clinical use country COVID-19 pandemic cross-reactivity detect Ecuador genomic Genomic surveillance gold gold standard IMPROVE individual individuals infectious agent International Laboratory limit of detection market multicenter Mutation Nasopharyngeal swab nasopharyngeal swabs new SARS-CoV-2 performance point of care positive prevalent Rapid RapiGEN RapiGEN® Ag test kit reduction in regulatory agencies RT-qPCR SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 surveillance SARS-CoV-2 transmission SARS-CoV-2 variants SARS–CoV–2 SD-Biosensor sensitivity setting shown South America South Korea Spain specificity Surveillance symptomatic individuals Test tested tropical variant [DOI] 10.3389/fcimb.2022.832235 PMC 바로가기 [Article Type] Multicenter Study
Acute odynophagia: A new symptom of COVID-19 during the SARS-CoV-2 Omicron variant wave in Sweden급성 연하곤란: 스웨덴 SARS-CoV-2 오미크론 변종 파동 중 COVID-19의 새로운 증상Case Reports Published on 2022-07-012022-09-11 Journal: Journal of internal medicine [Category] COVID19(2023년), SARS, 변종, [키워드] acute laryngitis Adults Affect affected affecting Antibiotics authority Bacterial infection Care Case series case sery case study clinical manifestation clinical symptom Clinical symptoms COVID-19 COVID-19 patient COVID-19 patients Department described diagnose diagnosed with COVID-19 ear edema Emergency Emergency Care emergency department epiglottitis Ethical approval Fever gold gold standard healthy Hospitalization in some inclusion criteria Infection Inflammatory Informed consent Laryngitis laryngitis. laryngotracheitis Larynx life-threatening Loss of Smell loss of smell and taste Lower respiratory tract management nose odynophagia olfactory dysfunction omicron Omicron variant Patient patients performed referred to retrospective review SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus secondary bacterial infection seeking single-center sore throat Swedish Swedish Ethical Review Authority Symptom Symptoms Taste the patient the SARS-CoV-2 the SARS-CoV-2 virus Throat upper airway upper airways vaccinated against COVID-19 variant variants of SARS-CoV-2 was obtained [DOI] 10.1111/joim.13470 PMC 바로가기 [Article Type] Case Reports