healthy individual – Page 5 – Communicable Diseases Research

Longitudinal Plasma Proteomics Analysis Reveals Novel Candidate Biomarkers in Acute COVID-19

세로형 플라즈마 단백질체학 분석, 급성 코로나19에서 새로운 후보 바이오마커 밝혀

Article

Published on 2022-04-012022-09-11
Journal: Journal of Proteome Research [Category] MERS, 바이오마커, 유전자 메커니즘, 진단,

Total antioxidant capacity as a marker of severity of COVID-19 infection: Possible prognostic and therapeutic clinical application

COVID-19 감염의 중증도 마커로서의 총 항산화 용량 : 가능한 예후 및 치료 임상 적용

Article

Published on 2022-04-012022-08-31
Journal: Journal of medical virology [Category] 바이오마커,

[키워드] activity antioxidant antioxidant enzyme blood sample Blood samples catalase causative pathogen collected Concentration control group COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 patient COVID-19 patients COVID-19 severity Defense dismutase Enzymes healthy individual healthy individuals healthy volunteer infected individual infected individuals Infection investigated marker Mild Mild disease nitric oxide oxidative stress Pathogenesis pathogenesis of SARS-CoV-2 Patient patients with COVID-19 Predictive prognostic Research SARS-COV-2 infection sera serum serum levels severe disease severely ill patients severity of COVID-19 statistically significant Superoxide Superoxide Dismutase susceptible TAC therapeutic Total total antioxidant capacity Variation was performed were measured with mild disease
[DOI] 10.1002/jmv.27500 PMC 바로가기 [Article Type] Article

Autoimmunity is a hallmark of post-COVID syndrome

자가면역은 포스트 코로나 증후군의 특징입니다

Comment

Published on 2022-03-162022-09-12
Journal: Journal of Translational Medicine [Category] MERS, SARS, 진단,

Angiotensin-converting-enzyme insertion/deletion polymorphism, ACE activity, and COVID-19: A rather controversial hypothesis. A case-control study

안지오텐신전환효소 삽입/제거 다형성, ACE 활성, 그리고 코로나19: 다소 논란의 여지가 있는 가설. 사례 대조 연구

Article

Published on 2022-03-012022-09-11
Journal: Journal of medical virology [Category] Fulltext, MERS, 변종, 유전자 메커니즘,

[키워드] ACE ACE activity ACE inhibitor ACE inhibitors ACE polymorphism allele alleles Analysis angiotensin angiotensin converting enzyme angiotensin converting enzyme. Angiotensin receptor blockers Angiotensin-converting enzyme arbitrary units carrier case-control study characterized complex conducted Control controls COVID-19 COVID-19 disease COVID-19 pandemic COVID-19 pathogenesis COVID-19 patient disease severity enzyme epidemiological data expressed First wave Generalized linear model Genotype genotypes healthy individual healthy individuals Hypothesis I/D genotype increased risk individuals insertion insertion/deletion limit mechanism Patient Poisson regression polymorphism Prevalence recruited reduction Renin renin-angiotensin system retrospective risk factor risk ratio risk ratios RRs SARS-CoV-2 severe disease severity shown synergy therapy was used
[DOI] 10.1002/jmv.27417 PMC 바로가기 [Article Type] Article

High Serum Progranulin Levels in COVID-19 Patients: A Pilot Study

COVID-19 환자의 높은 혈청 프로그래뉼린 수치: 파일럿 연구

Article

Published on 2022-03-012022-09-11
Journal: Biochemistry. Biokhimiia [Category] MERS, 바이오마커,

Application and Validation of SARS-CoV-2 RBD Neutralizing ELISA Assay

SARS-CoV-2 RBD 중화 ELISA 분석의 적용 및 검증

Article

Published on 2022-02-282022-09-11
Journal: Archives of Razi Institute [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] 95% CI absorbance acute respiratory syndrome acute respiratory syndrome coronavirus angiotensin Angiotensin-converting enzyme anti-RBD anti-SARS-CoV-2 IgG antibody application approach biosafety clinical evaluation Coefficient of determination Cohort Concentration convalescent convalescent plasma coronavirus disease Coronavirus disease 2019 Coronavirus-2 correlation COVID-19 COVID-19 patients COVID-19 vaccine COVID-19 vaccines demonstrated detect different time point different time points disease severity domain Donor Efficiency ELISA ELISA assay enzyme-linked immunosorbent enzyme-linked immunosorbent assay gold gold standard healthy individual healthy individuals host cell host cell receptor house human Angiotensin-converting enzyme individual Interaction Laboratory Live virus live viruses log methodology NAb NAbs nAbs. Neutralizing Neutralizing antibodies neutralizing antibody optical optical density pandemic processed Protein purified Quantitative RBD respiratory Safe SARS-CoV-2 SARS-CoV-2 nAbs SARS-CoV-2 RBD SARS-COV-2-RBD neutralizing ELISA assay sensitivity Seroprevalence serum sample serum samples specificity Spike protein standard curve statistical the spike protein Treatment treatment of COVID-19 patients validation viruses
[DOI] 10.22092/ARI.2021.356677.1890 PMC 바로가기 [Article Type] Article

Evaluation of the Levels of Peripheral CD3 + , CD4 + , and CD8 + T Cells and IgG and IgM Antibodies in COVID-19 Patients at Different Stages of Infection

감염 단계에서 COVID-19 환자에서 말초 CD3 +, CD4 + 및 CD8 + T 세포 및 IgG 및 IgM 항체의 수준의 평가

Research Article

Published on 2022-02-232022-08-31
Journal: Microbiology Spectrum [Category] MERS, 바이오마커, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Affect antibody production association Blood CD3 CD4 CD45 CD8 Cell Cell-mediated immunity Cellular immune response cellular immune responses cellular immunity changes in China clinical sample clinical samples collected conducted coronavirus COVID-19 cytometry analysis determine died ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay Flow flow cytometry Flow cytometry analysis groups healthy individual help Hospitalized IgG IgG and IgM IgM IgM and IgG immune responses immune system Immunity infected with SARS-CoV-2 Infection Level levels of antibodies levels of antibody lymphopenia main role medication moderate Patient patients patients with moderate peripheral Peripheral blood peripheral blood samples recovered patients reduction in reported respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 treatment SARS-CoV-2-infected patient SARS-CoV-2-infected patients serum sample serum samples severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe COVID-19 shown significant increase significantly Stage stimulatory Support T cell T cells Vaccine virus was performed were used
[DOI] 10.1128/spectrum.00845-21 PMC 바로가기 [Article Type] Research Article

Increased Interleukin 18-Dependent Immune Responses Are Associated With Myopericarditis After COVID-19 mRNA Vaccination

증가된 인터루킨 18 의존성 면역 반응은 COVID-19 mRNA 백신 접종 후 심근염과 관련이 있습니다

Immunology

Published on 2022-02-182022-09-12
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 진단,

[키워드] abnormality activated Activation administration Cardiac complications caused CD68 Cell characterized chest pain circulating Control controls COVID-19 COVID-19 mRNA Vaccination COVID-19 mRNA vaccine COVID-19 vaccination cytokine Cytokines disease onset dysfunction elevated expressed first dose Flow cytometry analysis healthy individual hearts IL-18 IL-27 Immune profile immune response incidence Increased individuals infiltration interleukin interleukin 18 mechanism mice Mild monocyte mRNA mRNA-1273 COVID-19 vaccine multiplex Myopericarditis NK cell NK cells NLRP3 inflammasome occur Patient phenotype progression response T cell Th1-type immune response the patient troponin I upstream vaccinated individual vaccination were used with COVID-19
[DOI] 10.3389/fimmu.2022.851620 PMC 바로가기 [Article Type] Immunology

Bean Extract-Based Gargle for Efficient Diagnosis of Active COVID-19 Infection Using Rapid Antigen Tests

신속한 항원 테스트를 사용하여 활성 COVID-19 감염의 효율적인 진단을 위한 콩 추출물 기반 가글

Research Article

Published on 2022-02-162022-09-10
Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술,

[키워드] Ag-RDT Ag-RDTs Alpha alpha and delta variants alternative analyzed Antigen Asymptomatic Bean canavalin clinical trial Concentration COVID-19 COVID-19 cases COVID-19 patient COVID-19 patients Delta delta variant Delta variants Detachment Detection sensitivity diagnostic diagnostic test domain early diagnosis efficient ENhance evaluated Evidence gargle hACE2 healthy individual healthy individuals ingredient initial intermolecular interaction intermolecular interactions less management Mass screening Nasopharyngeal swab nasopharyngeal swabs noninvasive NPs oral virus Patient patients hospitalized Physicochemical properties Rapid Rapid diagnostic test RDTs RT-PCR saliva specimen saliva specimens salivary SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 spike proteins SARS-CoV-2 variant screening process sensitivities sensitivity significantly Specificities specificity Spike proteins symptomatic symptomatic and asymptomatic Test tested the SARS-CoV-2 variants Viral Viral detection virus
[DOI] 10.1128/spectrum.01614-21 PMC 바로가기 [Article Type] Research Article

Immunogenicity of COVID-19 mRNA vaccines in immunocompromised patients: a systematic review and meta-analysis

Review

Published on 2022-02-122022-10-31
Journal: European Journal of Medical Research [Category] COVID-19,

[키워드] Analysis approach article Autoimmune autoimmune condition booster dose Control COVID-19 COVID-19 mRNA vaccine COVID-19 mRNA vaccines COVID-19 vaccination dose Efficacy evaluate finding fixed General population healthcare healthy individual Hematologic malignancy heterogeneity higher risk identify Immunocompromised Immunocompromised patient immunogenicity Infection kidney malignancy Meta-analysis morbidity Mortality mRNA COVID-19 vaccine on type organ Patient patients positive proportion random recipient recipients Result risk SARS-CoV-2 searched Seroconversion severe SARS-CoV-2 significantly higher statistically significant supplementary material systematic review transplantation vaccination was performed Web of Science
[DOI] 10.1186/s40001-022-00648-5 PMC 바로가기 [Article Type] Review