ACE2 Netlas: In silico Functional Characterization and Drug-Gene Interactions of ACE2 Gene Network to Understand Its Potential Involvement in COVID-19 SusceptibilityGenetics Published on 2021-08-272022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] ACE2 association binding site biological property categories characterization Colon conditions COVID-19 COVID-19 susceptibility database Dexamethasone diabetes domain drugs Evidence functional Genes Genetic variant Genetic variation Genome-wide association study GWAS highlight human genetic variation immune response immunological Inflammation Interaction Involvement kidney locus miRNA network performed phenotype Potential potential mechanism receptor Regulation responsible RORA RORC skeletal SLC12A6 SLC6A19 small intestine statistical statistically the SARS-CoV-2 Transmission variant [DOI] 10.3389/fgene.2021.698033 PMC 바로가기 [Article Type] Genetics
Case Report: Mitral Valve Involvement and First-Degree Atrial-Ventricular Block in Two Patients With Multisystem Inflammatory Syndrome in ChildrenPediatrics Published on 2021-08-062022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] Adults Aspirin Atrioventricular block block center Characteristics Child children children with MIS-C clinical Control Corticosteroid COVID COVID-19 defined described Evolution expressed Fever Follow-up heart involvement Hyperinflammatory Infection intravenous Intravenous immunoglobulin Involvement less management Mild MIS-C MIS-C multisystem inflammatory syndrome in children mitral Multiorgan outcome Pathogenesis presenting Rash reported Research SARS–CoV−2 Symptom syndrome therapy Treatment United State Valve was recorded World Health Organization [DOI] 10.3389/fped.2021.676934 PMC 바로가기 [Article Type] Pediatrics
SARS-CoV-2 Cardiac Involvement in Young Competitive Athletes젊은 경쟁 선수의 SARS-CoV-2 심장 관련Observational Study Published on 2021-07-272022-09-11 Journal: Circulation [Category] SARS, 임상, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus adverse outcomes age athlete Athletes cardiac cardiac event cardiac troponin Cardiopulmonary cardiovascular event Clinical characteristics clinical implication clinically collected complications of COVID-19 coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Definite determine diagnostic ECG event female Follow-up followed by Hospitalization hospitalizations hospitalized patient hospitalized patients imaging indicated Infection Involvement Lake magnetic resonance imaging median multicenter myocarditis Observational cohort study Odds ratio outcome positive predictor Prevalence Primary outcome required return to sport risk SARS-CoV-2 SARS-COV-2 infection secondary Secondary outcomes severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe coronavirus disease Sex Surveillance Symptom test result tested The United States transthoracic echocardiography troponin United States universities was performed [DOI] 10.1161/CIRCULATIONAHA.121.054824 PMC 바로가기 [Article Type] Observational Study
Retinal Involvement in COVID-19: Results From a Prospective Retina Screening Program in the Acute and Convalescent PhaseMedicine Published on 2021-06-242022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] “COVID-19 absence Acute acute phase age average Care Comorbidity convalescent convalescent phase coronavirus disease Coronavirus disease 2019 cotton wool spots COVID-19 COVID-19 diagnosis COVID-19 disease cross-sectional detect Diabetes Mellitus hemorrhage hemorrhages hospital discharge hypertension India Inflammation Involvement median median age North ocular Older Patient phase Program Prospective Result Retina Retinal retinopathy SARS-CoV-2 screened Screening Symptom Symptoms [DOI] 10.3389/fmed.2021.681942 PMC 바로가기 [Article Type] Medicine
Viruses Like Sugars: How to Assess Glycan Involvement in Viral AttachmentReview Published on 2021-06-072022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory syndrome advance Antiviral approaches attachment attachment receptor carbohydrate cellular tropism coronavirus Enterovirus D68 EV-D68 Genetic glycan HBGA heparan sulfate highlighting host cell identify identifying Interaction Involvement Like limitation majority pharmacological receptor recognize SARS-CoV-2 sialic acid targets Trigger viral infection virus viruses [DOI] 10.3390/microorganisms9061238 PMC 바로가기 [Article Type] Review
Cardiac Involvement in COVID-19 Patients: A Contemporary ReviewReview Published on 2021-06-012022-10-30 Journal: Infectious Disease Reports [Category] COVID-19, [키워드] administration Affect affected age alteration amplitude Analysis antivirals applied approach asymptomatic infection available data average cardiac cardiac magnetic resonance Cardiomyopathy cardiovascular therapy changes chest pain clinical manifestation Corticosteroid cough COVID-19 COVID-19 disease COVID-19 infection COVID-19 patient Critical death described diagnosed Diagnosis Diagnostic Criteria differential diagnosis disease ECG edema elevated Endomyocardial biopsy evaluated exhibited feature Fever healthy highlight histopathological imaging Immunoglobulin Infection Inflammatory biomarker Injury Involvement knowledge left ventricular dysfunction male management multiple organ failure myocarditis non-specific organ Patient patients patients with COVID-19 potential mechanism presenting symptom problems reported Research resonance Result review SARS-CoV-2 SARS-CoV2 Shortness of breath Symptom Symptoms Tachycardia therapy Treatment ventricular viral myocarditis was performed were measured while [DOI] 10.3390/idr13020048 PMC 바로가기 [Article Type] Review
Global REnal Involvement of CORonavirus Disease 2019 (RECORD): A Systematic Review and Meta-Analysis of Incidence, Risk Factors, and Clinical OutcomesMedicine Published on 2021-05-252022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI Acute kidney injury Admission affecting age AKI AKI patient Analysis association Chronic kidney disease clinical clinical presentation Clinical risk factors Comorbidity confidence interval coronavirus disease COVID-19 COVID-19 patient Critical database death Delay diabetes explained Factor heterogeneity history Hospital admission Hospitalization hypertension incidence incidence rate increase in independent variables internal medicine Involvement kidney transplant location manifestation Meta-analysis meta-regression meta-regression model Mortality Non-communicable disease non-communicable diseases observational study Odds ratio outcome Patient population level positive Prevalence Quantitative Quantitative data random-effect renal renal medicine renal replacement therapy Research review risk factor RRT stratified symptom onset systematic review was performed [DOI] 10.3389/fmed.2021.678200 PMC 바로가기 [Article Type] Medicine
Cardiac Involvement in Recovered Patients From COVID-19: A Preliminary 6-Month Follow-Up StudyCardiovascular Medicine Published on 2021-05-132022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] abnormality accompanied Admission Analysis analyzed Aspartate aminotransferase Biomarker cardiac cardiac injury Cardiac magnetic resonance imaging Cardiopulmonary circulating clinical coronavirus disease COVID-19 COVID-19 patient creatinine develop discharge discharged enrolled events Evidence Exercise capacity exhibited fibrosis Follow-up follow-up study form High-sensitivity C-reactive protein Hospitalization in both groups Inflammatory Inflammatory factor information Injury interquartile range Involvement Laboratory lactate dehydrogenase magnetic resonance imaging manifestation medications myocardial injury N-terminal nonspecific Patient peptide positive Premature proportion Quality of life recovered recovered patient recovered patients reported Self-reported symptoms sequence significantly higher ST-T changes ST2 statistical difference statistically significant difference sustained Symptom the patient troponin I university was collected Wuhan [DOI] 10.3389/fcvm.2021.654405 PMC 바로가기 [Article Type] Cardiovascular Medicine
Hydroelectrolytic Disorder in COVID-19 patients: Evidence Supporting the Involvement of Subfornical Organ and Paraventricular Nucleus of the HypothalamusCOVID-19 환자의 수전해 장애: 시상하부의 천골하 기관 및 방실 핵의 관련을 뒷받침하는 증거Review Published on 2021-05-012022-09-12 Journal: Neuroscience and biobehavioral reviews [Category] MERS, 진단, [키워드] acute respiratory syndrome angiotensin-converting enzyme-2 Blood Brain cause Central nervous system cerebrospinal fluid circulating CNS coronavirus COVID-19 COVID-19 patients disorder disrupt dysfunction Express homeostasis Hydroelectrolyte balance hypokalemia hypothalamus Infection interstitial Involvement lack mechanism modulating Multiple neurodegeneration neuroendocrine Neuroinflammation neuroinvasion neurological problem Neuron nucleus olfactory organ pathway Patient proteolytic receptor Region regions reported SARS-CoV-2 SARS-COV-2 infection Son Spread Supporting [DOI] 10.1016/j.neubiorev.2021.02.008 PMC 바로가기 [Article Type] Review
Adapting Behavioral Interventions for a Changing Public Health Context: A Worked Example of Implementing a Digital Intervention During a Global Pandemic Using Rapid Optimisation MethodsPublic Health Published on 2021-04-262022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] adaptation Analysis approach behavior change change Changing clinically COVID-19 demonstrated Digital effective Efficiency Engagement Evidence example facilitate feasible Germ Government Health help identify implementation Implementing IMPROVE information Intervention intervention - behavioral Involvement iterative Optimisation pandemic PPI Pragmatic provide provided Public public health Qualitative Rapid rapid research methods Research Self-isolation table Transmission transmitted Usage working [DOI] 10.3389/fpubh.2021.668197 PMC 바로가기 [Article Type] Public Health