lactating – Page 5 – Communicable Diseases Research

Efficacy and safety of nitazoxanide plus atazanavir/ritonavir for the treatment of moderate to severe COVID-19 (NACOVID): A structured summary of a study protocol for a randomised controlled trial

중등도에서 중증의 COVID-19(NACOVID) 치료를 위한 nitazoxanide + atazanavir/ritonavir의 효능 및 안전성: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Comparative Study

Published on 2021-01-042022-09-10
Journal: Trials [Category] 신약개발, 임상, 치료제,

Virucidal effect of povidone iodine on COVID-19 in the nasopharynx: A structured summary of a study protocol for an open-label randomized clinical trial

비인두에서 COVID-19에 대한 포비돈 요오드의 바이러스 살균 효과: 공개 라벨 무작위 임상 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2021-01-042022-09-10
Journal: Trials [Category] 임상,

[키워드] 6 hour 6 hours acute renal failure adverse effect adverse effects adverse event adverse events anticipated Arm-1 ARMS assigned baseline being randomized Blinding both groups chronic renal failure clinical trial college comparator Concentration conducted confirmed case COVID-19 COVID-19 case COVID-19 virus creatinine criteria Data analysis diagnosed diet disease dissemination distilled water DMC Efficacy element eligibility assessment estimated glomerular filtration rate evaluate exclusion filtration rate Final glomerular filtration rate groups Identifier in both groups include Inclusion inclusion criteria independent Informed consent Intervention intervention arm intervention arms intervention group invasive involved Iodine KDIGO lactating masking Microsoft Excel Modification nasal Nasal Irrigation Nasal spray nasopharynx Noninvasive ventilation number objective Occurrence Open-label Other outcome parallel-group participant Patient performed Placebo positive Povidone Iodine pregnant women Primary outcome proportion protocol random number generation randomization Randomized randomized clinical trial RCT receive recruited Registered renal renal disease renal failure required routine care Sample size screened sealed secondary outcome sensitivity Seven single-center Stage statistician status Study protocol supplementary material Symptom Thyroid thyroid disease Trial trial protocol Trial registration Version virucidal virus website
[DOI] 10.1186/s13063-020-04963-2 PMC 바로가기 [Article Type] Letter

Impact of COVID-19 on women and children and the need for a gendered approach in vaccine development

COVID-19가 여성과 어린이에 미치는 영향과 백신 개발에서 성별 접근의 필요성

Review

Published on 2020-12-012022-08-31
Journal: Human vaccines & immunotherapeutics [Category] MERS, 신약개발,

The efficacy of Siddha Medicine, Kabasura Kudineer (KSK) compared to Vitamin C & Zinc (CZ) supplementation in the management of asymptomatic COVID-19 cases: A structured summary of a study protocol for a randomised controlled trial

Letter

Published on 2020-10-272022-10-29
Journal: Trials [Category] Coronavirus, MERS, SARS,

[키워드] 1:1 accompany addition adverse effect Asymptomatic Asymptomatic COVID-19 baseline blinded breathlessness bronchial asthma calculated carried Chain Reaction changes in Chennai clinical clinical assessment clinical trial co-morbidity college control group cough COVID COVID-19 CTRI Data analysis determine Diabetes Mellitus dissemination dose Efficacy element eligibility assessment evaluate excluded exploratory Factor Fever filtered Herbal decoction hypertension IFNγ IL10 IL2 Immunity immunological independent India information investigator involved lactating malignancy management marker Medicine Microsoft Excel number objective Occurrence onset of symptom Open-label outcome parallel group participant positive pregnant Primary outcome progression protocol random number generation randomised randomised controlled trial randomization Randomized controlled trial receive recruit recruited recruitment reduced reducing reduction reduction in Registered reported RT-PCR Sample Sample size SARS-CoV-2 viral load sealed Secondary outcomes severe respiratory disease Siddha Siddha Medicine Standard state Study protocol submitted Symptom symptomatic Tablet tested the SARS-CoV-2 threshold TNF traditional methods Treatment Trial Tumor Vitamin website Zinc
[DOI] 10.1186/s13063-020-04823-z PMC 바로가기 [Article Type] Letter

A multi-center, randomized controlled trial by the Integrative Management in Japan for Epidemic Disease (IMJEDI study-RCT) on the use of Kampo medicine, kakkonto with shosaikotokakikyosekko, in mild-to-moderate COVID-19 patients for symptomatic relief and prevention of severe stage: a structured summary of a study protocol for a randomized controlled trial

Letter

Published on 2020-10-022022-10-29
Journal: Trials [Category] COVID-19, MERS, SARS,

[키워드] 1:1 Ability to communicate acute respiratory syndrome addition administration age Analysis antipyretics Arm Blinding calculated clinical clinical trial Combination common cold-like symptom control group coronavirus cough COVID-19 COVID-19 patient criteria decrease defined Dementia difficulty dissemination effective Efficacy element exclusion criteria fatigue female Fever Follow-up group H1N1 influenza hospitals Hypothesis IMPROVE in both group include Inclusion Infection Inpatient Japan Japanese Kampo Kampo medicines lactating less malaise Medicine Mild-to-moderate number objective occurred outcome Outpatient parallel-group participant Patient patients positive Prevention for severe stage previous study protocol Psychiatric random Randomized Randomized controlled trial receive recruited registry required Research Sample size SARS-CoV-2 Severe infection Severity of disease Shortness of breath significance level significantly sputum Stage steroid Study protocol survival survival curve Symptom Symptom relief symptomatic temperature the Kaplan-Meier method the log-rank test the median the primary endpoint the SARS-CoV-2 to define treated Treatment Two-arm website
[DOI] 10.1186/s13063-020-04746-9 PMC 바로가기 [Article Type] Letter

Development of early warning and rapid response system for patients with novel coronavirus pneumonia (COVID-19) A research protocol

3900

Published on 2020-08-212022-10-30
Journal: Medicine [Category] COVID-19, MERS,

[키워드] addition Adult patient build caused Clinical deterioration cohort study contagious Coronavirus disease 2019 COVID-19 COVID-19 patients Critical Critical care Critically ill Critically ill patient detect deteriorate Deterioration determine development diagnosed with COVID-19 disease disease severity driven by early warning example excluded hospital Hypothesis ICU immunosuppression state implementation include increase increased risk Intensive intensive care interval Intervention lactating medical resource mortality rate Novel coronavirus Nurses outcome Patient patient self-reporting patients Physicians Pneumonia pregnant Primary outcome problems proportion prospective cohort study provide public health rapid response recommendations recruited required Research Research protocol risk secondary significantly transfer Treatment Vaccine
[DOI] 10.1097/MD.0000000000021874 PMC 바로가기 [Article Type] 3900

Pakistan Randomized and Observational Trial to Evaluate Coronavirus Treatment (PROTECT) of Hydroxychloroquine, Oseltamivir and Azithromycin to treat newly diagnosed patients with COVID-19 infection who have no comorbidities like diabetes mellitus: A structured summary of a study protocol for a randomized controlled trial

당뇨병과 같은 동반 질환이 없는 새로 진단된 COVID-19 감염 환자를 치료하기 위한 Hydroxychloroquine, Oseltamivir 및 Azithromycin의 코로나바이러스 치료(PROTECT) 평가를 위한 파키스탄 무작위 및 관찰 시험: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약

Letter

Published on 2020-08-082022-08-13
Journal: Trials [Category] MERS, 임상,

[키워드] 1:1 adaptive age allocation sequence approval authority Azithromycin baseline bioethics blinded Blinding board clinical Clinical improvement clinical status Cohort cohort study Combination combinations Committee Comorbidity comparator computer-generated Controlled trial coronavirus COVID-19 diabete diabetes Diabetes Mellitus diagnosed disease dissemination distress drug dyspneic Effectiveness eight element evaluate excluded expected Final flexibility Follow-up followed by Formal Gender groups Hospitalized Hydroxychloroquine hypertension Infection intervention group kidney Kidney failure lactating liver medical condition monotherapy multi-center multicenter nasal swab nucleic acid number objective observation open open label Ordinal Scale oseltamivir parameter participant patients patients with COVID-19 PCR positive pregnant Primary outcome Primary outcomes protocol public health qRT-PCR random randomization Randomized Randomized controlled trial randomized study recruited recruitment regimen Registered Registration reported respiratory distress Safety Sample size Self-isolation Seven seven-category ordinal scale Standard status Study protocol subject subsequent sulfate test negative tested three groups treat Treatment Trial twice a day Version virus website
[DOI] 10.1186/s13063-020-04616-4 PMC 바로가기 [Article Type] Letter

Efficacy and safety of Anluohuaxian in the treatment of patients with severe Coronavirus disease 2019- a multicenter, open label, randomized controlled study: a structured summary of a study protocol for a randomised controlled trial

Letter

Published on 2020-06-082022-10-29
Journal: Trials [Category] Coronavirus, SARS,

[키워드] 6-minute walking distance actual Alpha analyst Anluohuaxian antiviral drugs brand bronchial asthma Care change changes Chinese Chinese herbal medicines chronic obstructive Colchicine Combined completion Compliance composed computer tomography Confirmed connective tissue control group Coronavirus disease 2019 COVID-19 criteria Cyclophosphamide cytokine diagnosed dissemination distribution drug Efficacy and safety element Endocrine enrolled Estimated evaluate expected experimental group explained facilitate fibrosis glucocorticoid groups hepatic fibrosis High-resolution history Hormones HRCT Huoshenshan Hospital Imatinib include indicate interferon-γ interstitial Interstitial lung disease investigators involved IWRS Kidney disease lactating liver lobular lung maximum Mental Disorders minimum multicenter Nasopharyngeal swab Necrosis negative neurologic Nintedanib nodule not blinded nucleic acid test number objective open label outcome outcome assessors participant Participants Pathogenesis pathway Patient pharmaceutical pill professional proportion protocol provided pulmonary pulmonary disease pulmonary fibrosis random randomised randomised controlled trial randomization randomization system Randomized Randomized controlled trial randomly divided RCT recruitment Research research drug respiratory specimen Sample size Science second selected severe COVID-19 sputum statistical status Study protocol subject technology therapeutic drug Tongji Hospital treated Treatment treatment group Trial Union Hospital university variety website West Wuhan Year
[DOI] 10.1186/s13063-020-04399-8 PMC 바로가기 [Article Type] Letter

A Novel Highly Divergent Protein Family Identified from a Viviparous Insect by RNA-seq Analysis: A Potential Target for Tsetse Fly-Specific Abortifacients

RNA-seq 분석을 통해 태생 곤충에서 식별된 매우 다양한 새로운 단백질 패밀리: 체체 파리 관련 낙태 환자의 잠재적 표적

Research Article

Published on 2014-04-242022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] Abortifacient addition African Amino acid amino acid sequence Analysis approaches casein cattle causative agents characterization coding control mechanisms Critical Differential analysis enrichment Factor family fecundity female functional genes encoding Genome genomic homeostasis Human Identified identify indicate insect Interference knockdown lactating lactation lipid metabolism maintenance mammalian mechanism mechanisms metabolism mother s milk novel occur organized Potential progeny Protein protein level protein synthesis Proteins proteome provided reduce reduced reducing Region reproductive resource RNA-Seq RNA-seq data secretion sequence similarity Seven shown similarities sleeping sickness specificity suppression synthesis target to define transcript Transcriptome transcripts Transferrin tsetse tsetse flies tsetse fly unique variant Viviparous were expressed while
[DOI] 10.1371/journal.pgen.1003874 PMC 바로가기 [Article Type] Research Article