IgG Antibodies Develop to Spike but Not to the Nucleocapsid Viral Protein in Many Asymptomatic and Light COVID-19 CasesIgG 항체는 스파이크에 발달하지만 많은 무증상 및 가벼운 Covid-9 사례에서 Nucleocapsid 바이러스 단백질이 아닙니다.Article Published on 2021-09-282022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, 치료법, 치료제, [키워드] ACE-2 receptor anti-RBD Anti-RBD IgG antibody Antibody detection Asymptomatic Asymptomatic case Cohort cohort of patient conducted correlated COVID-19 detectable disease severity domain help IgG IgG antibodies IgG antibody immune response Indicator individual Infection inhibit Interaction LIGHT lung lesion lung lesions majority moderate nucleocapsid nucleocapsid protein Protein raise RBD Receptor-binding domain remained SARS-CoV-2 serum Serum Neutralization severe symptoms severity spike Spike protein Symptom the antibody the disease the RBD the spike protein Viral [DOI] 10.3390/v13101945 PMC 바로가기 [Article Type] Article
The Use of Saliva as a Biosample in the Light of COVID-19Review Published on 2021-09-262022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] biobanking buffering solution collected COVID-19 COVID-19 pandemic description diagnostics disease equipment evaluated genetics information LIGHT methodology molecular Non-invasive operator Oral microbiome parameter Patient provided reproducibility Research Saliva salivaomics salivary SARS-CoV 2 SARS-CoV-2 detection stability [DOI] 10.3390/diagnostics11101769 PMC 바로가기 [Article Type] Review
Infrared light therapy relieves TLR-4 dependent hyper-inflammation of the type induced by COVID-19Brief Report Published on 2021-09-152022-10-31 Journal: Communicative & Integrative Biology [Category] COVID-19, [키워드] AP1 cause cellular change Clinical use condition costly COVID-19 COVID-19 infection COVID-19 patients COVID19 current Cytokine storm Cytokine storms decrease decreased expression disease distress downregulate Efficacy ELISA assay Gene Expression Host immune response human cells hyper-inflammation IL-6 IL-8 IL6 implicated Inflammation Inflammatory inflammatory conditions inflammatory response pathway infrared infrared light infrared therapy LIGHT Lungs marker gene mechanism modulation Mortality NFkB noninvasive observation occurred per day photobiomodulation therapy qPCR reactive oxygen species reduction in reporter resulting ROS Safe secreted cytokine Side effects therapy TNF-alpha treat Treatment [DOI] 10.1080/19420889.2021.1965718 PMC 바로가기 [Article Type] Brief Report
Rapid inactivation of SARS-CoV-2 by titanium dioxide surface coatingResearch Article Published on 2021-09-092022-10-28 Journal: Wellcome Open Research [Category] COVID-19, [키워드] acute respiratory syndrome ambient atomic Care coated with coating Complete Contamination coronavirus detectable droplet evaluated flow cytometry had no Health HIV-1 inactivated inactivation infected cell Infection infection control inoculated interval lentiviral system LIGHT live SARS-CoV-2 Live virus magnitude no significant difference Nosocomial infection occur Post-infection Protein pseudotyped pseudotyped virion Rapid reduction in remained SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 spike SARS-CoV-2 virus significant effect significantly spike spray stability surface target cell tested TiO2 titanium dioxide titre Transmissibility Transmission VERO E6 cells viability viral variant virus was determined [DOI] 10.12688/wellcomeopenres.16577.2 PMC 바로가기 [Article Type] Research Article
Solving the mystery of HBV-related mixed cryoglobulinemia: potential biomarkers of disease progressionHBV 관련 혼합 cryoglobulinemia의 미스터리 해결 : 질병 진행의 잠재적 바이오 마커Article Published on 2021-09-012022-08-31 Journal: Rheumatology (Oxford, England) [Category] SARS, 바이오마커, 치료기술, [키워드] addition analysed Biomarker Biomarkers Blood donors chain Clinical course Clinical data clinical evaluation COVID-19 patient cryoglobulinemia Disease progression distribution dysregulation Free free light chains HBV HBV infection healthy blood donor high risk identify IgG IgG subclasses Immunoglobulin Immunoglobulin G immunological immunosuppressive therapies impairment Inflammatory response LIGHT light chains liver mixed cryoglobulinemia MONITOR negative controls no significant difference open Patient patients Perspective Potential biomarker Precision Rheumatoid rheumatoid factor Sample serum IgG serum sample serum samples shown significant difference significantly increased stratified tested triggered two groups Vasculitis were used [DOI] 10.1093/rheumatology/keab157 PMC 바로가기 [Article Type] Article
Co-distribution of Light At Night (LAN) and COVID-19 incidence in the United StatesResearch Article Published on 2021-08-042022-10-28 Journal: BMC Public Health [Category] COVID-19, MERS, SARS, [키워드] Affect affecting ambient Analysis analyzed ArcMap association Clustering confounding variable Connecticut COVID-19 COVID-19 case COVID-19 incidence COVID-19 infection COVID-19 infections Diseases Factors Human immune system immune functions intensity LIGHT Light at night (LAN) lockdown lockdown policy Multiple linear regression New York Night performed positive correlation Racial Result selected severity significantly Spread supplementary material susceptibility the United State [DOI] 10.1186/s12889-021-11500-6 PMC 바로가기 [Article Type] Research Article
Autoantibodies against ACE2 and angiotensin type-1 receptors increase severity of COVID-19ACE2 및 지오텐신 1형 수용체에 대한 자가항체는 코로나19의 중증도를 증가시킵니다Article Published on 2021-08-012022-09-12 Journal: Journal of autoimmunity [Category] MERS, SARS, 진단, [키워드] ACE2 affecting angiotensin Angiotensin II association AT1 autoantibody Autoimmunity blocker clinical Comorbidity Control controls COVID-19 COVID-19 group COVID-19 patient COVID-19 severity defined Diagnosis discharge disease ENhance enzyme-linked immunosorbent assays females increase in Ligand LIGHT male Mild Mild disease moderate Necrosis non-infected outcome Outcome prediction Patient Pearson positive correlation Proinflammatory response Protective RAS receptor receptors reducing renin-angiotensin system SARS-CoV-2 scale serum Serum level severe patients severity of COVID-19 significant difference significantly higher significantly lower the WHO Treatment were measured [DOI] 10.1016/j.jaut.2021.102683 PMC 바로가기 [Article Type] Article
Tertiary Lymphoid Structures in Cancer: The Double-Edged Sword Role in Antitumor Immunity and Potential Therapeutic Induction StrategiesReview Published on 2021-07-292023-08-30 Journal: Frontiers in Immunology [Category] E형 간염, [키워드] bioengineering Immunotherapy LIGHT lymphoid neogenesis Tertiary lymphoid structures tumor immunity [DOI] 10.3389/fimmu.2021.689270 PMC 바로가기 [Article Type] Review
Virucidal Efficacy of Blue LED and Far-UVC Light Disinfection against Feline Infectious Peritonitis Virus as a Model for SARS-CoV-2Article Published on 2021-07-232022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] 405 nm blue light absence acute respiratory syndrome blue Combination coronavirus determine Disinfection effective Efficacy far-UVC Feline infectious peritonitis virus inactivation individual LIGHT light disinfection Model occur pandemic peritonitis reduction required respiratory droplet Saliva SARS-CoV-2 ultraviolet light viral inactivation virucidal virus wavelength Wet [DOI] 10.3390/v13081436 PMC 바로가기 [Article Type] Article
Cell Population Data and Serum Polyclonal Immunoglobulin Free Light Chains in the Assessment of COVID-19 SeverityArticle Published on 2021-07-152022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] Analysis analyzed antibody synthesis lymphocytes assessment AUC CBC chain Concentration COVID COVID-19 distinguishing Efficiency FLC Free granularity groups healthcare Healthcare system ICU Immunoglobulin indicate LIGHT lymphocyte material neutrophil no difference non-ICU nucleic acid Odds ratio parameter polyclonal Population risk stratification sensitivity serum severe COVID-19 shown Significant specificity [DOI] 10.3390/v13071381 PMC 바로가기 [Article Type] Article