Why does SARS-CoV-2 hit in different ways? Host genetic factors can influence the acquisition or the course of COVID-19SARS-CoV-2가 다른 방식으로 공격하는 이유는 무엇입니까? 숙주 유전적 요인은 COVID-19의 획득 또는 경과에 영향을 미칠 수 있습니다Review Published on 2021-06-012022-09-11 Journal: European journal of medical genetics [Category] SARS, 바이오마커, 변종, 유전자 메커니즘, [키워드] acquisition Affect age association available data carried CD27 Comorbidities Course COVID-19 COVID-19 pandemic COVID19 cure Data mining death demonstrated distribution epidemiological epidemiological data Evidence evidence of Factor FIVE General population Genes genetic background genetic risk factor genetic risk factors Genetic variant Host Host genetic factor Infection inhibitor Innate immunity involved list list of gene MBL2 Mutation outcome polymorphism population distribution Population screening Prevalence protease Protein provide response SARS-CoV-2 SARS-COV-2 infection Serine serine 2 SNPs supported term text mining TMPRSS2 transmembrane variant [DOI] 10.1016/j.ejmg.2021.104227 PMC 바로가기 [Article Type] Review
Efficacy and safety of Xuanfei Baidu granules for treating COVID-19 A protocol for systematic review and meta-analysis코로나19 치료를 위한 Xuanfei Baidu 과립의 효능 및 안전성 체계적인 검토 및 메타 분석을 위한 프로토콜 A4400 Published on 2021-05-212022-08-31 Journal: Medicine [Category] meta-analysis, SARS, 임상, 치료제, [키워드] Analysis average Baidu bias risk carried checked China Chinese clinical symptom Computed tomography Corona corona virus disease 2019 country COVID-19 COVID-19 diagnosis COVID-19 patient database Diagnosis disease effective Efficacy and safety evaluate evaluated evaluator Evidence extraction Granule Health Hospital stay include Infrastructure Intervention journal knowledge list lung management Meta Meta-analysis Negative conversion nucleic acid plan prevalent protocol Randomized controlled trials registration number registry released responsible review Science searched statistical systematic review technology Traditional Chinese medicine treating COVID-19 Treatment treatment of COVID-19 Trial Virus Disease Web website Wuhan Wuhan, China Xuanfei Baidu granule [DOI] 10.1097/MD.0000000000025653 PMC 바로가기 [Article Type] 4400
Influence of COVID-19 Pandemic Lockdown on Patients from the Bariatric Surgery Waiting ListArticle Published on 2021-05-172022-10-30 Journal: Medicina [Category] COVID-19, SARS, [키워드] Bariatric surgery Care Contact COVID-19 COVID-19 pandemic decrease dietary habit Factor female influence Isolation list lockdown maintaining majority male material obese obesity objective Patient physical activity reducing risk surgeon surgery the patient [DOI] 10.3390/medicina57050505 PMC 바로가기 [Article Type] Article
Repurposing existing medications for coronavirus disease 2019: protocol for a rapid and living systematic review2019년 코로나바이러스 질병에 대한 기존 약물 용도 변경: 신속하고 생생한 체계적 검토를 위한 프로토콜Protocol Published on 2021-05-072022-09-10 Journal: Systematic Reviews [Category] SARS, 신약개발, [키워드] acute respiratory syndrome Clinical data Clinical improvement Clinical studies clinical study clinicians and researchers Compound coronavirus disease Coronavirus disease 2019 COVID-19 database drug Efficacy effort Evidence group Hospital stay in vitro include intensive care intensive care unit Intubated list medication MERS-CoV methodology middle Middle East respiratory syndrome Coronavirus Middle Eastern Respiratory Syndrome Mortality proportion proportions protocol Repurposed repurposing Research respiratory SARS SARS-CoV2 Severe acute respiratory syndrome supplementary material sustained syndrome systematic review transferred Viral viral clearance [DOI] 10.1186/s13643-021-01693-7 PMC 바로가기 [Article Type] Protocol
Psychological Health Issues of Medical Staff During the COVID-19 OutbreakPsychiatry Published on 2021-04-302022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] 95% CI caused check China conducted COVID-19 COVID-19 outbreak cross-sectional Epidemics Epidemiology expected female Gender Health Service high risk hospital increased risk Infectious disease issue list medical staff moderate novel coronavirus disease outbreak Outbreaks Panic Prevalence problem problems Psychological psychological health psychological Impact significantly higher [DOI] 10.3389/fpsyt.2021.611223 PMC 바로가기 [Article Type] Psychiatry
Randomized clinical trial to compare the efficacy of ivermectin versus placebo to negativize nasopharyngeal PCR in patients with early COVID-19 in Peru (SAINT-Peru): a structured summary of a study protocol for randomized controlled trial페루의 초기 COVID-19 환자(SAINT-Peru)에서 비인두 PCR을 무효화하기 위해 이버멕틴 대 위약의 효능을 비교하기 위한 무작위 임상 시험(SAINT-Peru): 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-04-092022-09-01 Journal: Trials [Category] MERS, 임상, 진단, [키워드] 1:1 Administered adverse event allergy Amiodarone Anosmia Antiviral attending physician baseline blinded Blinding block childbearing age clarithromycin clinical clinical and laboratory parameters clinical care clinical trial Cobicistat coin conducted control group correlation cough COVID-19 COVID-19 disease COVID-19 patient COVID-19 pneumonia COVID-19 progression criteria Critical current cyclosporine CYP3A4 daily dose death determine determined by diagnosed diagnostic test Diltiazem dissemination dose drug early treatment Efficacy element Eligible patients emergency services enrolled epidemiologist erythromycin evaluate expected Fever follow-up visits generate hospital Hospitalization IgA IgG IgM IIa immune response immunomodulatory in vivo include inclusion criteria Indinavir Infection Informed consent inhibitor Intervention intestinal investigator investigators involved itraconazole Ivermectin ketoconazole laboratory parameter less list lung magnitude medical staff nasopharyngeal nasopharyngeal specimen Nasopharyngeal swab nasopharyngeal swab PCR nasopharyngeal swabs National negative number objective Older outcome oxygen oxygen saturation Parallel Arm participant Patient patients patients with SARS-CoV-2 PCR PCR cycle Peru Pharmacist phase Placebo placebo group placebo-controlled trial Pneumonia positive positive PCR test positive SARS-CoV-2 PCR pregnancy test pregnant women principal investigator progression proportion protocol quinidine randomization list Randomized Randomized controlled trial Randomly Rapid diagnostic test receive recruited reduce Registered Registration Result risk factor Risk factors Ritonavir Sample size SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR SARS-CoV-2 RNA SARS-CoV-2 viral load secondary Secondary objectives Seroconversion Seven severe disease severity spironolactone statistician status study population Study protocol supplementary material Symptom symptomatic Symptomatology Symptoms tacrolimus the patient the placebo group the SARS-CoV-2 threshold Treatment treatment group treatment groups treatment initiation Trial Trial registration two group two groups verapamil Viral Viral load virus Warfarin website with COVID-19 women [DOI] 10.1186/s13063-021-05236-2 PMC 바로가기 [Article Type] Letter
COVID-19—Importance for Patients on the Waiting List and after Kidney Transplantation—A Single Center Evaluation in 2020–2021Article Published on 2021-04-032022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] Allograft antibody BMI center Comorbidities Course COVID-19 develop dialysis disease effective examined Germany Hemodialysis high risk Hospitalized Humoral immunity hygiene Immunocompromised patient Immunocompromised patients immunosuppressed patient Infection infection with SARS-CoV-2 kidney Kidney transplantation list Mild MOST Neutralizing Patient patients probability of survival question recipient reflect SARS CoV-2 SARS-CoV-2 SARS-CoV-2 antibody SARS-COV-2 infection second wave shown smoking Symptom triggered vaccination Waiting list were infected [DOI] 10.3390/pathogens10040429 PMC 바로가기 [Article Type] Article
Sleep and Awakening Quality during COVID-19 Confinement: Complexity and Relevance for Health and BehaviorArticle Published on 2021-03-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Adults age Anxiety association Attitudes awakening Behavior Calamity Experience Check List check complexity Compliance COVID COVID-19 dependences Depression evaluate experience feeling females Gender General population Health Health professionals health-related behaviors identify individual irritability latency less list Logistic regression mental health mood morbidities Nurses patients physical activity positive positive attitude problems professional psychologists Quality Relevance risk significantly Sleep sleep disorder sleep patients sleep/awakening quality Stress subjects variable variables were used [DOI] 10.3390/ijerph18073506 PMC 바로가기 [Article Type] Article
A Resource for the Network Representation of Cell Perturbations Caused by SARS-CoV-2 InfectionSARS-CoV-2 감염으로 인한 세포 교란의 네트워크 표현을 위한 리소스Article Published on 2021-03-222022-09-10 Journal: Genes [Category] SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect approach approaches can be used causal network causal relationships caused cell physiology cellular cellular pathway cellular phenotype cellular phenotypes contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pathology drug effective effort enrichment analysis etiology framework functional Health high-throughput experiments hypothese information inhibitor inhibitors lack list majority molecular mechanism molecular mechanisms network offer pandemic pathology Pathways Perturbation produced Protein Proteins reported representation resource respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus Signaling signaling pathways subset the coronavirus disease 2019 (COVID-19) Therapeutic strategies Treatment Viral viral infection [DOI] 10.3390/genes12030450 PMC 바로가기 [Article Type] Article
Genomic Variations in SARS-CoV-2 Genomes From Gujarat: Underlying Role of Variants in Disease Epidemiology구자라트의 SARS-CoV-2 게놈의 게놈 변이: 질병 역학에서 변이의 기본 역할Genetics Published on 2021-03-192022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected allele frequency analyzed average caused clade Cluster coronavirus coronavirus disease Coronavirus disease 2019 country Course COVID-19 dataset datasets death death rate deaths Deceased Deleterious Ebola Evolution genomic Genomic surveillance GISAID globe Gujarat Haplotype haplotyping highest in viral include India list measles MERS Middle East Middle East respiratory syndrome Missense mutation Missense mutations Mortality Mutation mutation analysis National NCBI Novel coronavirus nucleocapsid ORF3a P -value Pandemics past Pathogenesis Pathogens Patient phylogenetic distribution recovered patient recovered patients respiratory role SARS-CoV-2 SARS-CoV-2 (2019-nCoV) SARS-CoV-2 genome SARS-CoV-2 genomes sequenced Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly syndrome variant variants Viral viral epidemiology viral genome viral genomes viral pathogenesis virulence while [DOI] 10.3389/fgene.2021.586569 PMC 바로가기 [Article Type] Genetics