Neglected tropical zoonotic diseases in Tigray region, northern Ethiopia: Spatial distribution and trend analysis of rabies, tuberculosis, schistosomiasis, and visceral leishmaniasis in humansArticle Published on 2021-11-012023-06-22 Journal: Zoonoses and Public Health [Category] 조류인플루엔자, [키워드] burden incidence rate mapping neglected tropical zoonosis. Tigray [DOI] 10.1111/zph.12874
Mapping SARS-CoV-2 Antibody Epitopes in COVID-19 Patients with a Multi-Coronavirus Protein MicroarrayResearch Article Published on 2021-10-272022-10-30 Journal: Microbiology Spectrum [Category] COVID-19, MERS, SARS, [키워드] accelerated accessory protein antibody antibody binding sites antibody reactivity antigenic applied binding changes in correlated correlation COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients cross-react cross-reactivity de novo ELISAs endemic human coronavirus enzyme-linked immunosorbent assay epitope Epitopes Evidence full-length HCoV HCoV-NL63 HCoV-OC43 help Human human coronaviruses identify IgA IgG IgM immune increasingly individual infect knowledge mapping MERS-CoV Microarray microneutralization Middle East Mutant SARS-CoV-2 N proteins Numerous ORF3a ORF7a other coronavirus overlapping Patient peptide Protein Proteins reactive reactivity Region regions Research respiratory syndrome coronavirus response responses responses against SARS-CoV SARS-CoV-2 SARS-CoV-2 protein sera shown specificity Spread structural protein the antibody response vaccination Vaccine-induced immunity variants of concern viral evolution viruses was used worldwide pandemic [DOI] 10.1128/Spectrum.01416-21 PMC 바로가기 [Article Type] Research Article
Mapping home internet activity during COVID-19 lockdown to identify occupation related inequalitiesArticle Published on 2021-10-262022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] accumulated adhere children Clustering conducted consequence contribute correlated COVID-19 COVID-19 pandemic demographic factor Diseases disparate employment Environmental social sciences Evidence Factor flexible help High-resolution Hypothesis identify Impact lockdown mapping proportion public health Risk factors secure Support virus spread [DOI] 10.1038/s41598-021-00553-7 PMC 바로가기 [Article Type] Article
Mapping of UV-C dose and SARS-CoV-2 viral inactivation across N95 respirators during decontaminationArticle Published on 2021-10-132022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, SARS, [키워드] approach complex COVID-19 pandemic distributions dose Efficacy flexible generate High-resolution highlighting identify inactivation mapping mitigate N95 respirator occupational health optical Optical metrology pathogen protocols public health quantification Quantitative resulting reuse robust SARS-CoV-2 SARS-CoV-2 viral substrate Variation viral inactivation yielding [DOI] 10.1038/s41598-021-98121-6 PMC 바로가기 [Article Type] Article
COVID-19-Associated Mucormycosis (CAM): An Updated Evidence MappingReview Published on 2021-09-302022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] age co-morbidity COVID-19 COVID-19 patient database diabetes Epidemiology Evidence facial Fungal infection glycemic control high mortality rate hypertension incidence male management mapping morbidity and mortality Mortality Mucormycosis Mycoses outcome outcomes OVID Pain Patient patients Primary outcome proptosis public health reduce renal reported surgical Symptom Treatment visual acuity was performed WHO [DOI] 10.3390/ijerph181910340 PMC 바로가기 [Article Type] Review
Mapping of the Covid-19 Vaccine Uptake Determinants From Mining Twitter DataScience - General Published on 2021-09-242022-10-30 Journal: Ieee Access [Category] COVID-19, [키워드] 6As taxonomy Characteristics Coverage COVID-19 determinant determinants of vaccine uptake Effectiveness Efficacy Factors Immunity immunization immunization hesitancy mapping National opinion Research SARS-CoV-2 Side effects the vaccine uptake vaccination Vaccination strategy Vaccine Vaccine acceptance Vaccine hesitancy [DOI] 10.1109/ACCESS.2021.3115554 PMC 바로가기 [Article Type] Science - General
COVID-19 Risk Mapping with Considering Socio-Economic Criteria Using Machine Learning AlgorithmsArticle Published on 2021-09-142022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Accuracy adaptive affecting Algorithm Algorithms AUC automated caused characteristic Concentration correlated correlation COVID-19 COVID-19 crisis COVID-19 patient criteria data-driven algorithms database disease distribution eight Feature selection geographic information system (GIS) health geography highest hospitals incompatible Initially Iran Logistic regression machine learning machine learning algorithm mapping patients with COVID-19 Pearson Pearson correlation pharmacies Pharmacy prevalence of COVID-19 Prevent Public random reduce reduction Region risk ROC Spatial modeling spread of COVID-19 Tehran Transport was obtained was performed [DOI] 10.3390/ijerph18189657 PMC 바로가기 [Article Type] Article
Degenerate CD8 Epitopes Mapping to Structurally Constrained Regions of the Spike Protein: A T Cell-Based Way-Out From the SARS-CoV-2 Variants Storm스파이크 단백질의 구조적으로 제한된 영역에 매핑되는 CD8 에피토프 변성: SARS-CoV-2 변이체 폭풍으로부터의 T 세포 기반 탈출구Review Published on 2021-09-082022-09-11 Journal: Frontiers in Immunology [Category] SARS, 변종, [키워드] Analysis analyzed arising B cell responses can not candidate CD8 CD8 T cell CD8 T cell epitopes CD8 T cell responses CD8 T cells CD8 T-cell Cell-mediated immunity compensated conserved COVID-19 vaccines cross-neutralization degenerate Efficacy ENhance epitope Epitopes Evolution expected HLA HLA class I HLA class I molecules immune response immune responses immunization immunodominant impairing inactivation limit maintain mapping mutate mutations Neutralizing antibodies Perspective Population Protective protective immunity Region response S-protein SARS-CoV-2 SARS-CoV-2 vaccines SARS-CoV-2 variants spike region stimulatory storm T cell T cell epitopes T cells the SARS-CoV-2 the Spike translational vaccination Vaccination strategies Vaccination strategy Vaccine Vaccines variant variants variants of concern Viral viral escape viral variant Viral variants [DOI] 10.3389/fimmu.2021.730051 PMC 바로가기 [Article Type] Review
New targets for drug design: importance of nsp14/nsp10 complex formation for the 3′-5′ exoribonucleolytic activity on SARS-CoV-2약물 설계를 위한 새로운 표적: SARS-CoV-2에 대한 3'-5' 엑소리보핵분해 활성에 대한 nsp14/nsp10 복합체 형성의 중요성Article Published on 2021-09-012022-09-11 Journal: The Febs Journal [Category] SARS, 신약개발, 치료제, [키워드] activities activity Amino acid amino acids antagonist antiviral drugs assembly biochemical C-terminal catalytic complex Consequences conserved coronavirus Coronaviruses Critical DEDD disrupt domain ExoN extreme global pandemic implication in vitro in vitro activity independent independent of inhibitor inhibitors Interaction interfere interferon involved life cycle mapping molecular Molecular modeling motif MTase multifunctional protein N-terminal New nsp10 nsp14 other coronaviruses pathogenesis of SARS-CoV-2 performed Protein Replication required residue RNase SARS-CoV-2 SARS-CoV-2 virus stimulated target triggered upregulating virus [DOI] 10.1111/febs.15815 PMC 바로가기 [Article Type] Article
Mapping single-cell data to reference atlases by transfer learningAnalysis Published on 2021-08-302022-10-04 Journal: Nature biotechnology [Category] MERS, SARS, 신약개발, [키워드] Analysis batch effect batch effects Brain Cell computational resource coronavirus disease COVID-19 Data integration dataset datasets de novo deep learning disease example facilitate healthy immune information iterative machine learning magnitude mapping pancreas parameter raw data single-cell transfer Variation [DOI] 10.1038/s41587-021-01001-7 PMC 바로가기 [Article Type] Analysis