Medical Research Council – Page 5 – Communicable Diseases Research

Genomic epidemiology and the role of international and regional travel in the SARS-CoV-2 epidemic in Zimbabwe: a retrospective study of routinely collected surveillance data

짐바브웨 SARS-CoV-2 전염병에서 게놈 역학과 국제 및 지역 여행의 역할: 일상적으로 수집되는 감시 데이터에 대한 후향적 연구

Article

Published on 2021-12-012022-09-11
Journal: The Lancet. Global health [Category] SARS, 변종, 유전자 메커니즘,

Disentangling post-vaccination symptoms from early COVID-19

Research paper

Published on 2021-12-012022-10-04
Journal: EClinicalMedicine [Category] 치료기술,

[키워드] 1:1 Asymptomatic AUC, area under the curve bMEM, Bayesian mixed-effect model BMI, Body mass index BNT162b2 ChAdOx1 nCoV-19 chronic CI, Confidence interval clinical information Community Comorbidities conducted cough Council COVID COVID-19 COVID-19 detection COVID-19, Coronavirus disease 2019 criteria Critical CSS CSS, COVID Symptoms Study demographic Department DI, Data invalid Early detection Engineering fatigue Fever finding foundation funding headache heart identifying individual infection control injection IQR, inter quartile range KCL, King's College London LFAT, Lateral flow antigen test Local LR, Logistic Regression Medical Research Council Mobile technology MOST myalgia NHS UK, National Health Service of the United Kingdom O-AZ, Oxford-AstraZeneca adenovirus-vectored vaccine overlap Oxford-AstraZeneca adenovirus-vectored vaccine participant Participants PB, Pfizer-BoiNTech mRNA vaccine Pfizer-BioNTech mRNA vaccine positive post-vaccination symptom presenting Prevent profile prospective observational study public health reduce reported symptom RF, Random forest ROC, Receiver operating curve rtPCR, Reverse transcription polymerase chain reaction SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test SARS-CoV-2, Severe acute respiratory syndrome-related coronavirus-2 Science Self-reported symptoms sensitivity Seven severe acute respiratory syndrome‐related coronavirus 2 (SARS-CoV-2) severe acute respiratory syndrome‐related coronavirus 2 (SARS-CoV-2) Side-effect Side-effects Spread Symptom Symptoms systemic symptom tested UK, United Kingdom of Great Britain and Nothern Ireland vaccination were recorded with COVID-19
[DOI] 10.1016/j.eclinm.2021.101212 PMC 바로가기 [Article Type] Research paper

Colchicine in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

Covid-19 (회복)로 병원에 입원 한 환자의 콜히친 : 무작위, 통제, 오픈 라벨, 플랫폼 시험

Randomized Controlled Trial

Published on 2021-12-012022-08-13
Journal: The Lancet. Respiratory Medicine [Category] MERS, SARS, 임상,

[키워드] (Medical Research Council) 1:1 28-day mortality allocation concealment Analysis anti-inflammatory actions assigned baseline both groups by mouth clinically suspected clinician Colchicine colchicine 1 mg colchicine group composite endpoint CYP3A4 CYP3A4 inhibitor death died Diltiazem discharge discharged Efficacy and safety eligible enrolled estimated glomerular filtration rate evaluate filtration rate finding followed by for inclusion Frequency funding glomerular filtration rate had no hospital Hospital stay hospitalised hospitals in Indonesia hospitals in Nepal in both groups Indonesia Innovation Intention intention-to-treat Invasive mechanical ventilation ISRCTN Laboratory less medical history Medical Research Council moderate nasogastric tube Nepal no significant difference Open-label open-label trial opinion participant Patient Platform trial Primary outcome proportion randomisation randomised Randomly rate ratio receive receiving RECOVERY trial reductions reductions in Registered risk risk ratio SARS-COV-2 infection secondary endpoint Secondary endpoints significant difference Standard of care subgroups of patients the patient Treatment treatment for COVID-19 Trial twice a day usual care usual care group web-based simple Wellcome Trust with COVID-19
[DOI] 10.1016/S2213-2600(21)00435-5 PMC 바로가기 [Article Type] Randomized Controlled Trial

Optimising health and economic impacts of COVID-19 vaccine prioritisation strategies in the WHO European Region: a mathematical modelling study

Research Paper

Published on 2021-11-302022-10-30
Journal: The Lancet Regional Health - Europe [Category] COVID-19,

[키워드] Adults age applied benefit Characteristics combinations Commonwealth Comorbidity compartmental model conditions Contact country Coverage COVID-19 COVID-19 mortality COVID-19 vaccine development disease Efficacy Epidemic Europe European European Commission evaluated examined finding Foreign foundation funding GDP greater group groups Health health economics highest Immunity Impact incrementally Infection less lowest Mathematical modelling Medical Research Council Melinda Gate Metrics Model morbidity Mortality multicountry analysis office Older Optimising outcome Policy evaluation profile reached Region reported Stage structures tested the WHO United Kingdom Vaccine vaccine policy Wellcome Trust WHO World Health Organization
[DOI] 10.1016/j.lanepe.2021.100267 PMC 바로가기 [Article Type] Research Paper

Social contact patterns and implications for infectious disease transmission – a systematic review and meta-analysis of contact surveys

Research Article

Published on 2021-11-252022-10-31
Journal: eLife [Category] COVID-19, MERS, SARS,

[키워드] 24 hours affected age age and gender all age groups Analysis asked baseline carried caused Characteristics collected consequence Contact Contact surveys country COVID-19 pandemic Critical declined Diseases Effect effective Effectiveness Evidence Frequency Gender help household size implication individual Infection Infectious disease information Interaction involved joint Medical Research Council Meta-analysis MOST None Older Outbreaks participant pathogen pathogen transmission Pathogens physical physical contact populations predict proportion reducing regions researcher respiratory pathogen risk factor SARS-CoV-2 shielding social contact social contact patterns social interaction Spread systematic review Transmission understanding
[DOI] 10.7554/eLife.70294 PMC 바로가기 [Article Type] Research Article

Predictors of Mortality in COVID-19-Positive Patients On and Off CPAP: A Review From a Tertiary Care Setting in the NHS

Internal Medicine

Published on 2021-11-202022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] affected affecting age Analysis cause collected consolidation coronavirus disease correlated Course COVID-19 COVID-19 patient CPAP creatinine diagnosed with COVID-19 England expired Final help identify inclusion criteria increased mortality Intubated James Cook lung lung involvement management Medical Research Council Mortality negative RT-PCR NHS objective Off outbreak pandemic Patient PCR test performance status Pneumonia positive airway pressure predictor predictors receiving respiratory rate Result review RT-PCR SARS-CoV-2 setting significantly small sample size Tertiary the disease the patient university virus were excluded
[DOI] 10.7759/cureus.19762 PMC 바로가기 [Article Type] Internal Medicine

Efficacy of FFP3 respirators for prevention of SARS-CoV-2 infection in healthcare workers

Research Advance

Published on 2021-11-162022-10-31
Journal: eLife [Category] COVID-19, MERS, SARS,

Non-pharmaceutical interventions, vaccination, and the SARS-CoV-2 delta variant in England: a mathematical modelling study

영국의 비약물적 개입, 백신 접종, SARS-CoV-2 델타 변종: 수학적 모델링 연구

Articles

Published on 2021-11-132022-09-10
Journal: Lancet (London, England) [Category] MERS, SARS, 변종,

[키워드] Alpha B.1.617.2 Bayesian calibrated the model capture Commonwealth condition country Coverage COVID-19 credible interval CrI cross-protection cumulative deaths delta variant described development Effectiveness England English Epidemic estimate Evidence finding Foreign funding hospital Hospital admission Hospital admissions Infection Intervention investigated lifting lockdown lockdown restriction lockdown restrictions Mathematical modelling Measures Medical Research Council mixing natural immunity NPI NPIs office pandemic parameter PCR testing per day population immunity reduced resulting risk SARS-CoV-2 transmission sensitivity step surveillance data the epidemic the SARS-CoV-2 the timing timeline Trajectories trajectory Transmissibility Transmission vaccination Vaccine variant variant of SARS-CoV-2 variants was done Wellcome Trust
[DOI] 10.1016/S0140-6736(21)02276-5 PMC 바로가기 [Article Type] Articles

Post-COVID-19 Sydrome and Decrease in Health-Related Quality of Life in Kidney Transplant Recipients after SARS-COV-2 Infection—A Cohort Longitudinal Study from the North of Poland

Article

Published on 2021-11-082022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic

Articles

Published on 2021-11-062022-10-04
Journal: Lancet (London, England) [Category] MERS, SARS, 유전자 메커니즘,

[키워드] affected age Anxiety Disorder anxiety disorders baseline cause caused conducted country COVID-19 COVID-19 pandemic criteria defined depressive determinant disorder estimate exacerbated Final finding foundation funding General population Google Scholar group health system Impact imperative inclusion criteria increases in information Intervention male Medical Research Council Melinda Gate Mental Mental disorder mental health meta-regression Mitigation mortality rate Older age pandemic poor mental health Prevalence promote reductions in reported response SARS-COV-2 infection searched Sex systematic review Taking treat unique urgency
[DOI] 10.1016/S0140-6736(21)02143-7 PMC 바로가기 [Article Type] Articles