Epidemiological and Genomic Analysis of SARS-CoV-2 in 10 Patients From a Mid-Sized City Outside of Hubei, China in the Early Phase of the COVID-19 OutbreakCOVID-19 발병 초기 단계에서 중국 후베이성 외곽의 중소 도시에서 10명의 환자에서 SARS-CoV-2의 역학 및 게놈 분석Public Health Published on 2020-09-182022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 유전자 메커니즘, [키워드] 2019-nCoV accumulated acute respiratory syndrome acute respiratory syndrome coronavirus average Belgium Characteristics China city Cluster complex Contact coronavirus coronavirus disease Coronavirus disease 2019 Coverage COVID-19 early phase early stage epidemiological family members feasible genomic Genomic analysis Genomic epidemiology Genotype globe highlighting knowledge metagenomic sequencing Mutation mutation rate nasopharyngeal sample Nasopharyngeal samples Novel coronavirus offer outbreak pandemic Patient PCR performed phase Real-time PCR respiratory SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 genomes Sequencing severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 sick significantly more SNP SNPs Taiwan Transmission Travel Viral viral genome viral genomes viral infection virus virus spread Wuhan Zhejiang [DOI] 10.3389/fpubh.2020.567621 PMC 바로가기 [Article Type] Public Health
Coronavirus discovery by metagenomic sequencing: a tool for pandemic preparednessArticle Published on 2020-08-212022-11-01 Journal: Journal of Clinical Virology [Category] COVID-19, MERS, SARS, [키워드] Amino acid assist bioinformatics capture Centrifuge classification clinical sample clinical samples clinical setting Combination contribute coronavirus Coronaviruses Coverage COVID-19 database detective diagnostic example genome coverage humans identity infect Laboratory MERS-CoV metagenomic metagenomic sequencing metagenomics NGS Novel coronavirus nucleotide pandemic probe protocol Result SARS-CoV SARS-CoV-2 SARS-CoV-2 pandemic sequencing depth the SARS-CoV-2 genome virus virus discovery viruses was tested [DOI] 10.1016/j.jcv.2020.104594 PMC 바로가기 [Article Type] Article
Evaluation of NGS-based approaches for SARS-CoV-2 whole genome characterisationRapid Communication Published on 2020-07-052022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] Amplicon sequencing amplicon-based enrichment approach ARTIC Network bioinformatics capture method characterisation Complete consensus sequence Coverage COVID-19 COVID-19 outbreak DNA enrichment evaluated Genome genome coverage genomes Genomic surveillance Genomics identity Illumina metagenomic metagenomic sequencing next generation sequencing NGS ONT ORF6 Oxford Nanopore Technology Panel performed producing protocol reference sequence Region required respiratory respiratory sample SARS-CoV-2 sequenced Sequencing SNP threshold Viral load WGS whole-genome sequencing [DOI] 10.1093/ve/veaa075 PMC 바로가기 [Article Type] Rapid Communication
Two Years of Viral Metagenomics in a Tertiary Diagnostics Unit: Evaluation of the First 105 CasesArticle Published on 2019-08-292023-08-30 Journal: Genes [Category] E형 간염, [키워드] clinical impact diagnostics metagenomic sequencing virus virus infection [DOI] 10.3390/genes10090661 PMC 바로가기 [Article Type] Article
Diagnostic Testing in Central Nervous System InfectionReview Article Published on 2019-06-022024-09-02 Journal: Seminars in neurology [Category] 대상포진, [키워드] diagnostic Encephalitis Meningitis metagenomic sequencing [DOI] 10.1055/s-0039-1688441 PMC 바로가기 [Article Type] Review Article
A metagenomic viral discovery approach identifies potential zoonotic and novel mammalian viruses in Neoromicia bats within South AfricaResearch Article Published on 2018-03-262022-10-28 Journal: PLoS ONE [Category] Coronavirus, Fulltext, 조류인플루엔자, [키워드] Adenoviridae Adenovirus African Amplicon sequencing Analysis anthropogenic approach bat bats Circoviridae coding collected Complete conserved Contact Conventional Coronaviridae coronavirus Coronaviruses Coverage determine eight fecal FIVE gene region generate genetic diversity Genome Herpesviridae highlighting Host hosts identify identity Illumina Miseq intestinal tissue lack library mammalian metagenomic metagenomic sequencing Middle East MiSeq nucleotide Papillomaviridae Parvoviridae PCR analysis PCR assay platform Population producing rectal Region regions Sample sequence sequenced sequencing data sequencing depth South Africa Specy Structure syndrome viral family Viral particles virus was determined were used widespread zoonotic [DOI] 10.1371/journal.pone.0194527 PMC 바로가기 [Article Type] Research Article