Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization입원 중 COVID-19 환자에서 변경된 구강 및 장내 미생물 및 SARS-CoV-2 바이러스 부하와의 연관성Article Published on 2021-07-222022-09-12 Journal: NPJ Biofilms and Microbiomes [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, [키워드] 16S rRNA Alpha alteration Altered association Bacterial baseline Biomarkers calculated clearance clearance of SARS-CoV-2 clinical microbiology collected Community COVID-19 COVID-19 patient COVID-19 patients digestive tract dimension disease elevated examined Fecal sample fecal samples Gut gut microbiota healthy individual healthy individuals Hospitalization identify Immune homeostasis indicated intestinal flora investigated maintenance microbe microbes microbial Microbiome pathophysiology Patient rRNA SARS-COV-2 infection SARS-CoV-2 viral load Sequencing severity Sex susceptibility throat swab Treatment strategies treatment strategy Viral load vital role vital roles [DOI] 10.1038/s41522-021-00232-5 PMC 바로가기 [Article Type] Article
The Coronavirus Disease 2019 (COVID-19): Key Emphasis on Melatonin Safety and Therapeutic EfficacyReview Published on 2021-07-202022-10-28 Journal: The Cochrane database of systematic reviews [Category] COVID-19, [키워드] acute respiratory syndrome addition adjuvant therapy Anti-inflammatory antioxidant backbone circadian rhythms clinical study clinical trials Contact coronavirus coronavirus disease COVID-19 Critical demonstrated Efficacy exacerbated homeostasis Host hosts immune response Infection infective Inflammation melatonin microbe Mitochondria oxidative pandemic Protective reactive oxygen respiratory diseases response Safety SARS-CoV-2 supported therapeutic action virus virus variant [DOI] 10.3390/antiox10071152 PMC 바로가기 [Article Type] Review
Application of an evidence-based, out-patient treatment strategy for COVID-19: Multidisciplinary medical practice principles to prevent severe diseaseCOVID-19에 대한 증거 기반 외래 환자 치료 전략의 적용: 중증 질환을 예방하기 위한 다학제 진료 원칙Review Published on 2021-07-152022-09-12 Journal: Journal of the neurological sciences [Category] MERS, SARS, 변종, 진단, 치료법, [키워드] alveoli application Bronchiole Budesonide COVID-19 COVID-19 pandemic Dexamethasone driven by early treatment entire spectrum Evolution Expectorate form Gas exchange human physiology individuals Inflammation Intervention L-albuterol methotrexate microbe molecular Mucus Mucus clearance oxygen saturation Postural percussion Prevent pulmonary Pulmonary hygiene pulse oximetry question raise respiratory muscle Respiratory muscle training risk SARS virus SARS-CoV-2 severe disease target tissues Treatment Vaccine Vaccine development Vibratory sonication viral family Vitamin D [DOI] 10.1016/j.jns.2021.117463 PMC 바로가기 [Article Type] Review
Level of Adherence to COVID-19 Preventive Measures Among Health Care Workers in Saudi ArabiaPreventive Medicine Published on 2021-06-272022-10-31 Journal: Cureus [Category] COVID-19, [키워드] acute respiratory syndrome adherence Arabic carried collected Contact coronavirus Coronavirus disease 2019 COVID-19 demonstrated diagnosed with COVID-19 Effectiveness English evaluate HCW HCWs high risk infection control Level male measure median age microbe pandemic Participants Patient care patients prevention preventive measure preventive measures questionnaire reduce reducing required SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission Saudi Arabia Transmission virus with COVID-19 worker [DOI] 10.7759/cureus.15969 PMC 바로가기 [Article Type] Preventive Medicine
Endothelial Senescence and Chronic Fatigue Syndrome, a COVID-19 Based HypothesisCellular Neuroscience Published on 2021-06-252022-10-31 Journal: Frontiers in Cellular Neuroscience [Category] COVID-19, [키워드] Abnormalities bacterial lipopolysaccharide Blood Brain cellular senescence characterized chronic COVID-19 COVID-19 pandemic disrupting Endothelial cell endothelial cells endotoxin tolerance etiology fatigue gastrointestinal tract Gut gut microbial community host protein impairment Infection Interaction intestinal memory microbe microbial microbial translocation other tissues Pain Pathogenesis Patient Premature promoted resulting senescence supported Symptom syndrome the SARS-CoV-2 the SARS-CoV-2 virus tiredness translocation triggered [DOI] 10.3389/fncel.2021.673217 PMC 바로가기 [Article Type] Cellular Neuroscience
Can Copper Products and Surfaces Reduce the Spread of Infectious Microorganisms and Hospital-Acquired Infections?Review Published on 2021-06-222022-10-30 Journal: Materials [Category] COVID-19, [키워드] addition Bacteria Can Community Complete Contact contribute copper coronavirus COVID-19 pandemic cultures disease disease-causing E. coli Epidemics events example form Health care healthcare healthcare facility healthy hospital Hospital admission increase in Infection infection control measure microbe microbial infections microorganism morbidity and mortality mortality rate outcomes pathogen pathogen transmission product promote PROTECT replacing resources SARS-CoV-2 significantly Spread subsequent suggested surface susceptible transfer Transmission Transport virus [DOI] 10.3390/ma14133444 PMC 바로가기 [Article Type] Review
Mobile phones of paediatric hospital staff are never cleaned and commonly used in toilets with implications for healthcare nosocomial diseasesArticle Published on 2021-06-212022-10-29 Journal: Scientific Reports [Category] Coronavirus, MERS, SARS, [키워드] alcohol categorical data Chi-squared test contributing to disease Diseases Disinfecting handling Health care healthcare healthcare worker Hospital staff implication microbe Mobile mobile phone nosocomial question questionnaire Risk factors SARS-CoV-2 virus Spread Swab Trojan horse unhygienic [DOI] 10.1038/s41598-021-92360-3 PMC 바로가기 [Article Type] Article
Identification of Lung and Blood Microbiota Implicated in COVID-19 PrognosisArticle Published on 2021-06-102022-10-31 Journal: Cells [Category] COVID-19, MERS, SARS, [키워드] Analysis Anti-inflammatory BALF Blood blood microbiota Bronchoalveolar lavage fluid contribute coronavirus Coronavirus disease 2019 correlated COVID-19 COVID-19 prognosis COVID-19 severity cytokine downregulation identification IL-4 immune immune dysregulation implication Inflammation inflammatory pathway inflammatory pathways lung Lung microbiota microbe Microbiome mononuclear cell pathway PBMC Peripheral blood Prognosis SARS-CoV-2 Signaling signaling pathway therapy tissue treating COVID-19 patients upregulation [DOI] 10.3390/cells10061452 PMC 바로가기 [Article Type] Article
Plasma Markers of Disrupted Gut Permeability in Severe COVID-19 Patients중증 COVID-19 환자의 장 투과성 장애를 나타내는 혈장 표지자Immunology Published on 2021-06-092022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, [키워드] applied approach Bacterial Blood cause clinical implications contribute coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity Crosstalk disease severity Diseases disrupt Disrupted Disruption exacerbate functions fungal glycome glycomics Gut gut barrier integrity highlight immune activation implicated Inflammation Injury intestinal investigated Lipidomics lung Lung injury marker metabolome metabolomics microbe microbes microbial microbial translocation mortality rate negative controls permeability Plasma marker plasma markers plasma metabolome plasma sample plasma samples positive positive feedback resulting SARS-CoV-2 severe coronavirus disease severe COVID-19 severity systemic inflammation Systems biology tight junction translocation zonulin [DOI] 10.3389/fimmu.2021.686240 PMC 바로가기 [Article Type] Immunology
Reversion of Gut Microbiota during the Recovery Phase in Patients with Asymptomatic or Mild COVID-19: Longitudinal StudyArticle Published on 2021-06-072022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] 16S rRNA Amplicon sequencing applied Asymptomatic Bacteroidetes changed COVID-19 determine Effect FB ratio Fecal sample Gastrointestinal symptom Gut gut microbiota healthy controls Infection intestinal longitudinal longitudinal analysis microbe Microbiome Mild Modifying Negative conversion Patient patients with asymptomatic phase profile reported respiratory infection respiratory symptoms reversion SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA SARS-CoV2 selected significantly increased therapeutic Viral RNA was performed with COVID-19 [DOI] 10.3390/microorganisms9061237 PMC 바로가기 [Article Type] Article