PostCOVID effect on endothelial function in hypertensive patients: A new research opportunityOpinion Published on 2021-11-162022-10-29 Journal: Journal of clinical hypertension (Greenwich, Conn. [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] cardiovascular risk factor circulating circulating free DNA Complication contribute COVID‐19 disease Diseases DNA Effect endothelial Endothelial cell Endothelial dysfunction endothelial function endothelial microparticles Evidence flowmetry hypertension hypertensive hypertensive patients Ischemia Laser‐Doppler flowmetry Microparticle Pandemics plasma report Research resources rising SARS CoV‐2 SARS‐CoV‐2 Vascular vascular disease vasodilatation [DOI] 10.1111/jch.14376 PMC 바로가기 [Article Type] Opinion
Humoral responses to SARS-CoV-2 mRNA vaccines: Role of past infectionSARS-COV-2 mRNA 백신에 대한 체액 반응 : 과거 감염의 역할Research Article Published on 2021-11-082022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, [키워드] antibody Antibody titers biologic BNT162b2 BNT162b2 vaccine BNT162b2 vaccines booster completion decay demonstrated Department detect dose enrolled fire first responders Health Service Humoral response humoral responses immune responses immunoassay implication individual individuals infected individual Infection Los Angele Los Angeles magnitude median Microparticle mRNA mRNA vaccine mRNA-1273 mRNA-based vaccine mRNA-based vaccines naïve naïve individuals NPI pandemic protective immune response remains uncertain required respiratory Responder robust antibody response robust antibody responses role SARS-CoV-2 SARS-CoV-2 spike Severe acute respiratory syndrome spike subset two-dose regimen understanding University of California Vaccine vaccine dose vaccinee vaccinees was used [DOI] 10.1371/journal.pone.0259703 PMC 바로가기 [Article Type] Research Article
Probability-Based Estimates of Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence and Detection Fraction, Utah, USA중증 급성 호흡기 증후군 코로나바이러스 2 혈청 유병률 및 검출 비율의 확률 기반 추정치, 미국 유타주Research Published on 2021-11-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age antibodies case detection collected coronavirus coronavirus 2 coronavirus disease COVID-19 detect detection detection rate Effectiveness estimate fraction generate IgG immunoassay Immunoglobulin G incidence Infection infections Microparticle Nasopharyngeal swab nasopharyngeal swab sample Nasopharyngeal swab samples nasopharyngeal swabs participant PCR PCR-positive population surveillance Prevalence probability sampling design public health Randomly respiratory respiratory infections response reverse transcription PCR rRT-PCR SARS SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 detection SARS-CoV-2 IgG SARS-CoV-2–positive sensitivity Seroepidemiologic studies serology Seroprevalence serum sample serum samples severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specificity unbiased estimate United States USA Utah viruses zoonoses [DOI] 10.3201/eid2711.204435 PMC 바로가기 [Article Type] Research
Prevalence of SARS-CoV-2 antibodies in healthy blood donors from the state of Tyrol, Austria, in summer 20202020년 여름 오스트리아 티롤 주의 건강한 헌혈자에서 SARS-CoV-2 항체의 유행Observational Study Published on 2021-10-262022-09-12 Journal: Wiener Klinische Wochenschrift [Category] MERS, SARS, 임상, 진단, [키워드] 95% CI 95% confidence interval Abbott acute respiratory syndrome acute respiratory syndrome coronavirus age antibody association Blood blood donor Blood donors Characteristics Cohort COVID-19 cross-sectional Cross-sectional studies determine District Donor Epidemiology female finding fold Gender health authorities Health authority healthy blood donor healthy blood donors IgG immunoassay individual Landeck Local Logistic regression Loss of Smell medication Microparticle not differ Observational cohort study Odds ratio participant reported SARS-CoV-2 antibody SARS-CoV‑2 SARS-CoV‑2 infection screened seronegative seropositive participant seropositive participants Seropositivity Seroprevalence severe acute respiratory syndrome Coronavirus Spread summer Symptoms Taste tested Travel Variation [DOI] 10.1007/s00508-021-01963-3 PMC 바로가기 [Article Type] Observational Study
Evaluation of Endothelial Dysfunction and Inflammatory Vasculopathy After SARS-CoV-2 Infection—A Cross-Sectional StudyCardiovascular Medicine Published on 2021-10-132022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Affect antibodies antibody arginine Arterial stiffness asymmetric atherosclerotic C-reactive protein capillary capillary changes cardiovascular disease Cell Compound contributing to COVID-19 cross-sectional design endothelial Endothelial dysfunction erythrocyte sedimentation rate evaluate Evolution healthy control homoarginine identify immunological parameters Inflammation Inflammatory inflammatory condition interleukin-6 mechanism metabolism Microparticle morphology MOST parameter Patient post-COVID-19 patient Post-COVID-19 patients SARS-CoV-2 SARS-COV-2 infection selected Variability Vascular endothelium Vascular injury Vasculopathy von Willebrand factor were measured [DOI] 10.3389/fcvm.2021.750887 PMC 바로가기 [Article Type] Cardiovascular Medicine
Validation of Commercial SARS-CoV-2 Immunoassays in a Nigerian Population나이지리아 인구에서 상용 SARS-CoV-2 면역분석의 검증Research Article Published on 2021-10-062022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료법, [키워드] Abbott Algorithm anti-SARS-CoV-2 Architect assay Bio-rad caution Characteristics China confirmation country COVID-19 COVID-19 pandemic Disease prevalence effort ELISAs Endemic enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays estimate Euroimmun Europe evaluated exposure to FIVE hepatitis B highlight HIV positive IgG immunoassay Immunoglobulin Immunoglobulin G IMPROVE independent lead limit Microparticle much lower negative sample Nigeria nucleocapsid protein Omega pathogen Pathogens PCR PCR-positive patient plasma Population populations positive public health reported SARS-CoV-2 SARS-CoV-2 IgG sensitivities sensitivity Sensitivity and specificity serological Serological assay serological assays serology Seroprevalence Serosurvey Serosurveys Specificities specificity specimen Spread Total validation widespread [DOI] 10.1128/Spectrum.00680-21 PMC 바로가기 [Article Type] Research Article
A Review on Current COVID-19 Vaccines and Evaluation of Particulate Vaccine Delivery SystemsReview Published on 2021-09-272022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] accelerate acute respiratory syndrome Administered administration approved benefit Compliance contagious coronavirus Coronavirus-2 country COVID COVID-19 current Defense delivery develop died dosage elicit form forms Immunity immunize limitation Microparticle mucosal oral particulate vaccine pandemic Particulate Patient platform preserved public health reported review Saliva SARS-CoV-2 Spread System temperature transported vaccinate vaccination Vaccine Vaccines virus Wuhan, China [DOI] 10.3390/vaccines9101086 PMC 바로가기 [Article Type] Review
Comparison of Dried Blood Spots and Venous Blood for the Detection of SARS-CoV-2 Antibodies in a Population of Nursing Home Residents요양원 거주자 모집단에서 SARS-CoV-2 항체 검출을 위한 건조 혈반과 정맥혈의 비교Comparative Study Published on 2021-09-222022-09-12 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, [키워드] Abbott acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect analyzed antibodies Antibody testing Blood capillary CMIA collected coronavirus COVID-19 DBS sample DBS samples detection dried blood spot Dried blood spots elderly ELISA ELISA cutoff enzyme-linked immunosorbent enzyme-linked immunosorbent assay Euroimmun evaluate Finger prick General population home IgG IgG antibodies immune response immune responses immunoassay immunoglobins implementation iterative Microparticle Nursing nursing home nursing homes Older pandemic performed Population positive Protein ranged reduced reference population reference test resident room temperature SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgG SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody SARS-CoV-2 vaccine SARS-CoV-2 vaccines SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody sensitivities sensitivity serological test Serological testing Serological tests serology Serosurveillance serum samples specific antibodies Specificities specificity spot statistical study population subjects temperature vaccination venipuncture venous venous blood Whatman [DOI] 10.1128/Spectrum.00178-21 PMC 바로가기 [Article Type] Comparative Study
Co-Spray Dried Nafamostat Mesylate with Lecithin and Mannitol as Respirable Microparticles for Targeted Pulmonary Delivery: Pharmacokinetics and Lung Distribution in RatsArticle Published on 2021-09-192022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] acute respiratory syndrome Administered administration Analysis blood plasma Bronchoalveolar lavage fluid caused co-spray coronavirus Coronavirus disease 2019 COVID-19 distribution Dry powder inhaler Ex vivo in vitro in vivo inhibitor intratracheal administration intravenous lecithin lung lung tissue mannitol mesylate Microparticle nafamostat Nafamostat mesylate new strain pharmacokinetics pulmonary RAT respiratory tract SARS-CoV-2 SARS-CoV-2 S spray stability suppresse tissue transmembrane serine protease [DOI] 10.3390/pharmaceutics13091519 PMC 바로가기 [Article Type] Article
Quantitation of antibodies against SARS-CoV-2 spike protein after two doses of CoronaVac in healthcare workers의료 종사자에서 코로나백 2회 투여 후 SARS-CoV-2 스파이크 단백질에 대한 항체 정량Article Published on 2021-09-012022-09-12 Journal: Journal of medical virology [Category] 진단, [키워드] Abbott acute respiratory syndrome Adaptive immune response age Anti-spike anti-Spike IgG antibody Antibody titer Chemiluminescent microparticle immunoassay chronic disease Chronic diseases CoronaVac coronavirus cutoff value detection dose facilitate female first dose Frequency greater group HCW HCWs healthcare healthcare worker Healthcare workers help highest Humoral immunity immunoassay indicated less male median men Microparticle performed positive produced quantitation recruited reported Result SARS-CoV-2 SARS-CoV-2 IgG SARS-CoV-2 spike protein second dose Seropositivity serum sample significantly significantly higher the antibody response the spike protein the vaccine Turkey university hospital vaccination was performed women [DOI] 10.1002/jmv.27098 PMC 바로가기 [Article Type] Article