K18- and CAG-hACE2 Transgenic Mouse Models and SARS-CoV-2: Implications for Neurodegeneration Research
K18- 및 CAG-hACE2 형질전환 마우스 모델 및 SARS-CoV-2: 신경변성 연구에 대한 시사점
Review
[키워드] absence
ACE2
acute respiratory syndrome
acute respiratory syndrome coronavirus
acute respiratory syndrome coronavirus 2
angiotensin
Angiotensin-converting enzyme
angiotensin-converting enzyme 2
antiviral drug
Autopsy
Brain
brain regions
brain tissue
CAG-hACE2 transgenic mice
caused
cells
Central nervous system
Confusion
Consequences
coronavirus
COVID-19
COVID-19 patient
COVID-19 patients
Cytokines
demonstrated
develop
direct infection
disorder
disorders
dissect
Encephalitis
entry receptor
enzyme
evaluate
glial cell
global pandemic
hACE2
helping
human Angiotensin-converting enzyme
Human brain
increase in
infected with SARS-CoV-2
Inflammation
K18
K18-transgenic mice
leukocyte
leukocyte infiltration
life
manifestation
mechanism
Meningitis
Mental
Model
molecular
mouse
Mouse models
mucosa
neuroinvasion
neurological
Neurological complication
Neurological complications
neuronal
neurons
olfactory
Patient
periphery
pro-inflammatory cytokine
pro-inflammatory cytokines
provoke
Quality of life
reported
responses
robust
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 neuroinvasion
severe acute respiratory syndrome Coronavirus
suggested
survivor
therapy
transgenic
Transgenic mouse
Vaccine development
[DOI] 10.3390/molecules27134142 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/molecules27134142 PMC 바로가기 [Article Type] Review