Vaccine-Induced Subacute Thyroiditis (De Quervain’s) after mRNA Vaccine against SARS-CoV-2: A Case Report and Systematic ReviewSystematic Review Published on 2022-02-212022-10-30 Journal: Infectious Disease Reports [Category] COVID-19, [키워드] ACE-2 acute respiratory syndrome Administered angiotensin-converting enzyme-2 ASIA syndrome association blood tests Case report cells coronavirus database De Quervain demographics described disease expressed follicular Follow-up implicated Inc Infection initial item mRNA mRNA vaccine mRNA-based vaccine Pathogenesis Patient Patient record performed Pfizer receptor report Reporting review SARS-CoV-2 SARS-CoV-2 vaccine SAT searched statistical analysis statistically significant difference Subacute Symptom systematic review Thyroid Thyroiditis Topic USA vaccination Vaccine viral infection was performed women [DOI] 10.3390/idr14010018 PMC 바로가기 [Article Type] Systematic Review
The Kinetics of COVID-19 Vaccine Response in a Community-Vaccinated Population지역사회 백신 접종 인구에서 COVID-19 백신 반응의 역학Article Published on 2022-02-152022-09-12 Journal: Journal of immunology (Baltimore, Md. : 1950) [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] analyzed collected COVID-19 IgG individual individuals Kinetics Moderna mRNA-based vaccine noninvasive patients Pfizer Population prevaccination Quantitative quantitative assay response Saliva salivary Sample SARS-CoV-2 S1 second vaccination subset vaccination vaccine response widespread [DOI] 10.4049/jimmunol.2100919 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Immunization Orchestrates the Amplification of IFNγ-Producing T Cell and NK Cell PersistenceImmunology Published on 2022-02-142022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] adjusted age amplification association B cell boost CD4 CD8 Cohort concerning confounder correlation COVID-19 death develop dose doses effective Effectiveness group groups HCW healthcare worker hematologic IgG immune protection immune response Immunity immunological protection intervals kinetic Lymphocytes mRNA BNT162b2 mRNA-based vaccine NK NK cell NK cells novel pandemic parameter PBMC Pfizer polymerase chain positive prime immunization protective immunity recipient responders Result risk SARS-CoV-2 SARS-COV-2 infection stimulated subset T cell T cells the vaccine two-dose regimen vaccination Vaccines virus [DOI] 10.3389/fimmu.2022.798813 PMC 바로가기 [Article Type] Immunology
COVID-19 Vaccination Safety and Tolerability in Patients Allegedly at High Risk for Immediate Hypersensitivity ReactionsArticle Published on 2022-02-142022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] adenoviral vector allergy Analysis anaphylaxis Cell Cohort cohort of patient COVID-19 COVID-19 vaccination criteria disease doses female HAE Hereditary angioedema high risk hypersensitivity hypersensitivity reaction IHR Immediate incidence indication Mastocytosis Mild MOST mRNA-based COVID-19 vaccine mRNA-based vaccine occurred Occurrence Patient patient group patients pediatric performed protocol reaction reported retrospective risk Safe Safety SARS-CoV-2 Sex significantly Symptom Symptoms Tolerability vaccination vaccine dose Vaccines were assessed [DOI] 10.3390/vaccines10020286 PMC 바로가기 [Article Type] Article
Lipid Nanoparticle Delivery Systems to Enable mRNA-Based TherapeuticsReview Published on 2022-02-112022-10-28 Journal: Pharmaceutics [Category] COVID-19, [키워드] approval approved candidate clinically COVID-19 delivery develop disease Efficacy Emergency use evaluated gene editing genetic disease Genetic diseases global pandemic issue lesson Lipid Lipid nanoparticles LNP mRNA mRNA platform mRNA-based mRNA-based therapeutics mRNA-based vaccine mRNA-LNP nanoparticle Onpattro Pharmaceutics platform prophylactic vaccines PROTECT SARS-COV-2 infection siRNA-LNP Spread System therapeutic Therapeutics translation treat Treatment University of Pennsylvania utility Vaccine [DOI] 10.3390/pharmaceutics14020398 PMC 바로가기 [Article Type] Review
Circulating extracellular vesicle microRNAs associated with adverse reactions, proinflammatory cytokine, and antibody production after COVID-19 vaccinationArticle Published on 2022-02-082022-10-04 Journal: NPJ Vaccines [Category] 바이오마커, [키워드] Activation adjuvants Adverse reaction Adverse reactions antibody production Antibody titers Biomarker BNT162b2 circulating conducted correlated COVID-19 COVID-19 vaccination Efficacy EVs Extracellular extracellular vesicle Fever immune responses less local pain lymphocyte microRNA miRNA mRNA-based vaccine Pain pandemic Proinflammatory cytokine prospective cohort study RNA vaccines second dose sera serum systemic adverse reaction systemic symptoms TNF-α Vaccine vaccine efficacy Vesicle [DOI] 10.1038/s41541-022-00439-3 PMC 바로가기 [Article Type] Article
mRNA Covid-19 vaccines in pregnancy: A systematic reviewResearch Article Published on 2022-02-022022-10-28 Journal: PLoS ONE [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] adverse event adverse events Adverse reaction antibody Antibody Response antibody transfer article available data booster clinical Cochrane Library conducted Coronavirus disease 2019 criteria database described develop dose elicit European fatigue fetal first vaccination FIVE headache IgG infection rate injection interval investigated latency Local manual Moderna mRNA mRNA vaccine mRNA vaccines mRNA-based vaccine objective observational study Pain Pfizer–BioNTech Pregnancy pregnant women Prevent registry reported Research responses Result risk factor robust Safe SARS-CoV-2 SARS-COV-2 infection searched Seven suggested systematic review systemic adverse events the WHO union vaccination Vaccine vaccine dose were excluded [DOI] 10.1371/journal.pone.0261350 PMC 바로가기 [Article Type] Research Article
B Cell Composition Is Altered After Kidney Transplantation and Transitional B Cells Correlate With SARS-CoV-2 Vaccination ResponseMedicine Published on 2022-02-022022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 105 patient affected Altered Analysis antibody Antigen B cell B cells Blood BNT162b2 CD27 CD5 CD86 change CKD CKD G5 collected COVID-19 COVID-19 pandemic dialysis dose double negative downregulated Efficacy explain expression flow cytometric Follow-up Frequency heterogeneous immune response implication increased mortality individuals investigated kidney kidney transplant recipient Kidney transplantation lymphocyte memory mRNA-1273 mRNA-based vaccine naïve non-responders Patient patients Peripheral blood plasmablast recruited reduced remained response Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination seroconversion rate serological response shown significantly subjects subpopulation subset transplantation vaccination Vaccination strategies venous was performed [DOI] 10.3389/fmed.2022.818882 PMC 바로가기 [Article Type] Medicine
Antibody Responses after SARS-CoV-2 Vaccination in Patients with Liver Diseases간 질환 환자에서 SARS-COV-2 백신 접종 후 항체 반응Brief Report Published on 2022-01-212022-09-01 Journal: Viruses [Category] 진단, 치료기술, [키워드] Adequate advanced age age anti-SARS-CoV-2 anti-SARS-CoV-2 antibody Antibody titers Breakthrough infection cirrhosis coefficient Control controls correlated Efficacy Humoral response humoral responses IgG antibodies IgG antibody Immunosuppression Immunosuppressive treatment Liver disease liver diseases mRNA-based vaccine multivariable analysis Neutralizing activity no difference no differences Patient paucity of data post vaccination profiles reported response Safe SARS-CoV-2 SARS-CoV-2 vaccine seroconversion rates Side effect symptomatic vaccination [DOI] 10.3390/v14020207 PMC 바로가기 [Article Type] Brief Report
Kinetics of the Antibody Response to Boostering With Three Different Vaccines Against SARS-CoV-2Immunology Published on 2022-01-192022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, [키워드] Against amplitude Antibody Response B-cell response BNT162b2 Cell ChAdOx1 nCoV-19 change collected detect detectable driven by early response examined first dose Frame Heterologous heterologous vaccination regimen homologous IgA IgA response IgA responses IgG IgG response immune response immunogenic increase increases in Kinetics latency marker mRNA-1273 mRNA-based vaccine neutralization Neutralization assay no difference participant performed plasma populations regimen regimens response responses Result SARS-CoV-2 second dose second vaccination serum sample Seven shown the antibody response vaccination while [DOI] 10.3389/fimmu.2022.811020 PMC 바로가기 [Article Type] Immunology