The COVID-19 Pandemic Situation in Malaysia: Lessons Learned from the Perspective of Population DensityCase Report Published on 2021-06-182022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] approach collected Community Contagion contagious diseases Containment measure coronavirus COVID-19 COVID-19 case COVID-19 cases COVID-19 infection cumulative density disease exacerbated Hypothesis Impact infection rate Intervention lesson Malaysia Ministry of Health Non-pharmaceutical measures P -value Pearson correlation Pearson correlations Population population density R 2 risk severity of COVID-19 situation spatio-temporal spike Spread Support variable virulence virus website [DOI] 10.3390/ijerph18126566 PMC 바로가기 [Article Type] Case Report
CT Quantification of COVID-19 Pneumonia at Admission Can Predict Progression to Critical Illness: A Retrospective Multicenter Cohort StudyMedicine Published on 2021-06-172022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Admission age Analysis Aspartate aminotransferase automatically benefit calculated Can Chest computed tomography Chest CT Chinese Clinical management collected consolidation coronavirus disease correlation COVID-19 COVID-19 guideline COVID-19 patients Critical Critical illness cutoff value death defined erythrocyte sedimentation rate Evidence feature ground-glass opacity groups High-sensitivity C-reactive protein highest imaging initial intensive care Laboratory laboratory data laboratory-confirmed lactate dehydrogenase lymphocyte male mechanical ventilation medical records negative correlation neutrophil outcome Patient patients patients with COVID-19 Pearson correlation Pneumonia pneumonia lesion positive correlation PPV predict Prognostic marker progression quantification quantified Quantitative Respiratory failure Retrospective study sensitivity Shock specificity System Trial urea nitrogen variable Volume were assessed were excluded [DOI] 10.3389/fmed.2021.689568 PMC 바로가기 [Article Type] Medicine
Decreased Low-Density Lipoprotein Cholesterol Level Indicates Poor Prognosis of Severe and Critical COVID-19 Patients: A Retrospective, Single-Center StudyMedicine Published on 2021-05-262022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Acute cardiac injury Admission Analysis cardiac injury Characteristics Comorbidity Coronavirus disease 2019 correlated COVID-19 COVID-19 patient COVID-19 patients critical COVID-19 patient critical COVID-19 patients Critically ill patient CRP level death Decreased dysfunction dyslipidemia enrolled four group four groups global public health group Hospitalization ICU immune increased risk Inflammation Injury intensive care LDL-C Level lipoprotein liver dysfunction Low-density lipoprotein Low-Density Lipoprotein cholesterol Lymphocyte count mechanical ventilation Mortality not differ Patient Pearson correlation Poor poor prognosis positively correlated Prognosis proportion reduction renal dysfunction severe and critical COVID-19 patients severe patients Shock shown Symptom treated [DOI] 10.3389/fmed.2021.585851 PMC 바로가기 [Article Type] Medicine
Is Higher Subjective Fear Predictive of Post-Traumatic Stress Symptoms in a Sample of the Chinese General Public?Psychiatry Published on 2021-05-202022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] 95% CI addition addressed affected checklist Chinese conducted COVID-19 COVID-19 outbreak disorder DSM-5 Epidemic fear general public health Hierarchical index medical resource mental health mental illness outbreak Pearson correlation Pittsburgh positive correlation post-traumatic post-traumatic stress symptom Post-traumatic stress symptoms Predictive PTSD Quality question questionnaire regression analysis Sample selected Sleep sleep quality statistical analyses Stress subject Subjective subjective fear Symptom total effect total score was measured were measured were used [DOI] 10.3389/fpsyt.2021.560602 PMC 바로가기 [Article Type] Psychiatry
SARS-CoV-2 infection activates a subset of intrinsic pathways to inhibit type I interferons in vitro and in vivoSARS-CoV-2 감염은 시험관 내 및 생체 내에서 I형 인터페론을 억제하기 위해 고유 경로의 하위 집합을 활성화합니다Research Paper Published on 2021-04-282022-09-10 Journal: International Journal of Medical Sciences [Category] MERS, SARS, 유전자 메커니즘, [키워드] activate Analysis antiviral response Cell circadian rhythm correlated epithelial evade Evidence expression facilitate ferrets Health Host host cell host cells IFNB1 IFNs immune immune evasion in vitro in vivo inhibit inhibitory inhibitory effect innate antiviral responses interferons intrinsic intrinsic pathway limit Longitudinal data mechanism NHBE pathway Pathways Pearson correlation performed peroxisome phosphatidylinositol Previous studies previous study SARS-CoV-2 SARS-COV-2 infection Signaling subset TNF signaling type I IFNs type I interferon type I interferons Viral viral infection virus [DOI] 10.7150/ijms.56630 PMC 바로가기 [Article Type] Research Paper
Single-cell analysis of angiotensin-converting enzyme II expression in human kidneys and bladders reveals a potential route of 2019 novel coronavirus infection인간의 신장과 방광에서 안지오텐신 전환 효소 II 발현의 단일 세포 분석은 2019년 신종 코로나바이러스 감염의 잠재적 경로를 보여줍니다Article Published on 2021-04-202022-09-11 Journal: Chinese medical journal [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] 2019 novel coronavirus 2019-nCoV 2019-nCoV infection ACE2 ACE2 expression ACE2 gene Acute kidney injury acute respiratory syndrome addition Analysis angiotensin Angiotensin-converting enzyme bioinformatics bladder Cell cell type cells co-expression coronavirus disease Coronavirus disease 2019 datasets detectable enzyme II epithelial cells evaluate Evidence evidence of expression Fever healthy house human kidney in urine independent Infection intermediate cell kidney kidney damage nCoV Novel coronavirus p value p values Patient Pearson correlation Pearson correlation coefficient provided proximal proximal convoluted tubule proximal tubule recent findings receptor Respiratory complications reveal SAME AS sequencing data Severe acute respiratory syndrome single-cell analysis Single-cell RNA sequencing subtype urinary system Urine virus [DOI] 10.1097/CM9.0000000000001439 PMC 바로가기 [Article Type] Article
The Causality Inference of Public Interest in Restaurants and Bars on Daily COVID-19 Cases in the United States: Google Trends AnalysisOriginal Paper Published on 2021-04-062022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, [키워드] addition affected average Bar bars can be used Care Causality coronavirus country COVID-19 COVID-19 outbreak COVID-19 pandemic Daily deep learning example Google Google Trends greater Health help highest Inference infodemiology information infoveillance interest linear relationship lowest LSTM machine learning objective observation occurred outcomes p value Pearson correlation positive Predictive programming provide Public restaurant restaurants Result significant effect significantly the United State The United States trend [DOI] 10.2196/22880 PMC 바로가기 [Article Type] Original Paper
Public Discourse Against Masks in the COVID-19 Era: Infodemiology Study of Twitter DataOriginal Paper Published on 2021-04-052022-10-31 Journal: JMIR Public Health and Surveillance [Category] COVID-19, MERS, [키워드] Against Analysis category collected coronavirus correlation Course COVID-19 COVID-19 case COVID-19 cases COVID-19 pandemic curtail demonstrated discourse English event Evidence help identify Intervention investigated Mask Masks media objective pandemic Pearson correlation Policy prevalent Public public health raising reported Result social medial, opinion analysis spread of COVID-19 The United States Topic Volume wearing mask wearing masks [DOI] 10.2196/26780 PMC 바로가기 [Article Type] Original Paper
COVID-19 as a worldwide selective event and bitter taste receptor polymorphisms: An ecological correlational studyResearch article Published on 2021-04-012022-10-05 Journal: International journal of biological macromolecules [Category] 유전자 메커니즘, [키워드] activity allele Analysis analyzed AVI bitter taste correlation country COVID-19 COVID-19 mortality death death rate dysfunction ecological Efficiency epidemiological extraoral G allele Genes Gustatory immune system Immunity Meta-analysis methodology Mortality mucosal not significant olfactory pathophysiology patients with COVID-19 Pearson correlation polymorphism positive correlation raise recent finding receptor Result selective SPSS systematic review TAS2R38 TAS2R38 gene Vaccine was obtained while [DOI] 10.1016/j.ijbiomac.2021.02.070 [Article Type] Research article
The networks of m 6 A-SARS-CoV-2 related genes and immune infiltration patterns in idiopathic pulmonary fibrosisResearch Paper Published on 2021-03-152022-10-28 Journal: Aging (Albany NY) [Category] COVID-19, SARS, [키워드] Algorithm Analysis association cells cellular characteristic CIBERSORT Cohort contribute coronavirus disease correlation COVID-19 COVID-19 infection COVID-19 pandemic Cox model dataset develop Diseases evaluated Gene Expression Gene Expression Omnibus gene expression pattern genetic link hazard identify Idiopathic pulmonary fibrosis immune immune cells immune infiltration immune response infiltration IPF Lung disease Methylation N6-methyladenosine operator Pathways patients Pearson correlation poor prognosis Prognosis pulmonary fibrosis regulated reported Research RNA modification SARS-CoV-2 SARS-COV-2 infection similarity tissue Treatment was obtained was performed was used were used [DOI] 10.18632/aging.202725 PMC 바로가기 [Article Type] Research Paper