Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID-19; a systematic review and meta-analysis of randomized clinical trialsCOVID-19 환자에서 표준 치료/위약 대비 토실리주맙의 효능 및 안전성 무작위 임상 시험의 체계적인 검토 및 메타 분석Review Published on 2022-05-012022-09-11 Journal: British Journal of Clinical Pharmacology [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 95% CI adverse event all-cause mortality assessment Bia carried certainty certainty of evidence clinical trial controlled trials coronavirus coronavirus disease COVID-19 COVID-19 patient Critical data extraction Efficacy Efficacy and safety evaluate evaluated event events incidence include mechanical ventilation Meta-analysis methodology moderate Mortality nine Patient patients with COVID-19 peer-reviewed progression Randomized randomized clinical trial Randomized controlled trial RCT RCTs reduce reported responsible risk Risk of bias risk ratio SAE searched Serious Adverse Events systematic review therapy Tocilizumab tocilizumab administration variety [DOI] 10.1111/bcp.15124 PMC 바로가기 [Article Type] Review
Pharmacological interventions to prevent Covid-19 disease: A rapid reviewCovid-19 질병을 예방하기 위한 약리학적 개입: 신속한 검토Review Published on 2022-05-012022-09-12 Journal: Reviews in Medical Virology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] article certainty of evidence Combination coronavirus coronavirus disease COVID-19 determine drug intervention Effectiveness high quality evidence high risk incidence Intervention Ivermectin monoclonal antibody peer-reviewed pharmacological intervention Placebo Prevent prevention Prophylaxis protective effect randomised controlled trial RCT RCTs reduce reduced reported risk of bia Risk of bias SARS-CoV-2 SARS-COV-2 infection Severity of disease significantly Support symptomatic and asymptomatic symptomatic disease tested Trial Vaccines Viral load while [DOI] 10.1002/rmv.2299 PMC 바로가기 [Article Type] Review
Light acupuncture and five-element music therapy for nurses’ mental health and well-being during and post-COVID-19: protocol for a randomised cross-over feasibility study코로나19 기간 및 이후 간호사의 정신 건강과 웰빙을 위한 가벼운 침술 및 5요소 음악 요법: 무작위 교차 타당성 연구를 위한 프로토콜Article Published on 2022-04-292022-09-11 Journal: BMJ Open [Category] 임상, [키워드] affected Analysis Anxiety asked assessments Blinding clinical clinical trial Combination Community Complete COVID-19 pandemic cross-over Depression depression & dissemination Edith eligible engage Ethical approval Ethics ethics committee evaluate Evidence feasibility Feasibility study form Health healthcare professionals hospital Human Impact IMPROVE include Intention International Intervention Laser Laser therapy LIGHT Local management mental health mood disorders music therapy National New Nurse online questionnaire online questionnaires PAIN MANAGEMENT participant peer-reviewed performed Primary outcome profession protocol Quality of life randomised recruited registration number required Research Ethics research findings resulting secondary outcome Secondary outcomes Studio therapeutic effect therapy Treatment treatment group Trial Two-arm university Well-being [DOI] 10.1136/bmjopen-2021-057106 PMC 바로가기 [Article Type] Article
Comparison of standard prophylactic, intermediate prophylactic and therapeutic anticoagulation in patients with severe COVID-19: protocol for the ANTICOVID multicentre, parallel-group, open-label, randomised controlled trial중증 COVID-19 환자에 대한 표준 예방, 중간 예방 및 치료 항응고 요법의 비교: ANTICOVID 다기관, 병렬 그룹, 공개 라벨, 무작위 대조 시험에 대한 프로토콜Article Published on 2022-04-262022-09-11 Journal: BMJ Open [Category] 임상, [키워드] absence all-cause mortality anticoagulation approved bleeding body mass body mass index Clinical improvement Clinical practice clinical scale Coagulopathy component Computed tomography COVID-19 criterion D-dimer D-dimer level D-dimer levels death defined dysfunction Efficacy and safety ethical committee Ethics ethics committee Evolution extension extreme followed by France French Hierarchical High-dose Hospital stay Ile include induce intensive care intensive care unit Invasive mechanical ventilation life low-dose lung major bleeding event Microvascular thrombosis multicentre Multiorgan Open-label outcome oxygen parallel-group Paris pathophysiological Patient patients patients with COVID-19 peer-reviewed primary endpoint Prophylactic protocol pulmonary artery Quality of life randomisation randomised randomised controlled randomised controlled trial randomised trials receive recruit registration number renal renal failure respiratory respiratory infections secondary Secondary outcomes Sepsis sepsis-induced coagulopathy severe COVID-19 stratified submitted the primary endpoint therapeutic anticoagulation Thromboembolism thrombosis thrombotic Trial trials Vasopressor venous ventilator weight [DOI] 10.1136/bmjopen-2021-059383 PMC 바로가기 [Article Type] Article
COVID-19 GPH: tracking the contribution of genomics and precision health to the COVID-19 pandemic responseCOVID-19 GPH: COVID-19 대유행 대응에 대한 유전체학 및 정밀 건강의 기여도 추적Article Published on 2022-04-252022-09-11 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] abundance article articles artificial intelligence center Control COVID-19 COVID-19 pandemic database defined disease control domain Genomics Health include information knowledge Knowledge management machine learning management manual curation Microbiology office Open Access pandemic pathogen peer-reviewed Precision Precision public health prevention produced Public public health SARS-CoV-2 unique [DOI] 10.1186/s12879-022-07219-3 PMC 바로가기 [Article Type] Article
Influence of socioeconomic status on functional recovery after ARDS caused by SARS-CoV-2: a multicentre, observational studyObservational Study Published on 2022-04-222022-10-05 Journal: BMJ Open [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory distress alteration approved ARDS Berlin criteria Care caused Chest CT chest CT scan cohort study Compliance COVID-19 Critical Critical care defined Desaturation develop diagnosed discharge disease eligible Ethics facilitator finding Follow-up form functional Health healthcare High-flow nasal oxygen hospitalised ICU identify impair include Inclusion independent individual influence informed consent form initial Intensive intensive & intensive care International lung multicentre National outcomes oxygen Patient patients with COVID-19 peer-reviewed performed Primary outcome Prognosis protection protocol Pulmonary function tests Quality of life rehabilitation respiratory Respiratory function respiratory infections Respiratory Support risk SARS-COV-2 infection Severe case severity Study protocol syndrome [DOI] 10.1136/bmjopen-2021-057368 PMC 바로가기 [Article Type] Observational Study
Clinical efficacy and safety of high-flow nasal cannula (HFNC) in acute hypoxaemic patients with COVID-19: a protocol for a systematic review and meta-analysisCOVID-19를 가진 급성 저산소병 환자에서 고유 유량 코 캐뉼라 (HFNC)의 임상 효능 및 안전성 : 체계적인 검토 및 메타 분석을위한 프로토콜Article Published on 2022-04-122022-08-31 Journal: BMJ Open [Category] meta-analysis, [키워드] Acute respiratory failure adult intensive & age and sex approach Caregivers clinical Clinical efficacy Cochrane Library Continuous data COVID-19 COVID-19 patient COVID-19 patients Critical Critical care data extraction determine develop disease severity Efficacy and safety eligibility criteria Ethical approval Ethics evaluate for inclusion HFNC High-flow nasal cannula hypoxaemic respiratory failure identify increased risk Infection transmission infections Intensive intensive care intensive care unit intubation mean difference meta-analyses Meta-analysis Mortality nasal nasal cannula outcome Participants Patient peer-reviewed performed Primary outcome PROSPERO protocol randomised controlled trial RCT RCTs registration number required respiratory Respiratory failure respiratory infections risk risk of bia risk ratio secondary outcome Secondary outcomes Subgroup analyses subgroup analysis systematic review the mean Treatment undergo Web of Science [DOI] 10.1136/bmjopen-2021-057743 PMC 바로가기 [Article Type] Article
Neuromodulation through brain stimulation-assisted cognitive training in patients with post-COVID-19 cognitive impairment (Neuromod-COV): study protocol for a PROBE phase IIb trial코로나19 이후 인지 장애 환자의 뇌 자극 보조 인지 훈련을 통한 신경 조절(Neuromod-COV): PROBE 2b상 시험을 위한 연구 프로토콜Article Published on 2022-04-112022-09-11 Journal: BMJ Open [Category] 임상, [키워드] among others anodal approach behavioural Brain clinical trials cognitive Cognitive impairment cognitive impairments cognitive performance cognitive training Combination COVID-19 defined develop diagnosed with COVID-19 Direct Current disease severity double-blinded Effect Effects Ethical approval Ethics ethics committee Evidence follow-up assessment follow-up assessments Greifswald IIb include International Intervention life measure Medicine memory mental health muscle relaxation National NEUROLOGY neuromodulation Open-label outcome Patient peer-reviewed postintervention Primary outcome Quality of life randomised receive registration number Relaxation training Result secondary Secondary outcomes Study protocol Symptom Symptoms Therapeutic approach these symptoms Trial university Working memory [DOI] 10.1136/bmjopen-2021-055038 PMC 바로가기 [Article Type] Article
Characterisation of the long-term physical and mental health consequences of SARS-CoV-2 infection: A systematic review and meta-analysis protocolSARS-CoV-2 감염의 장기적인 신체적, 정신적 건강 결과의 특성화: 체계적인 검토 및 메타 분석 프로토콜Article Published on 2022-04-052022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), meta-analysis, SARS, [키워드] Abstract abstracts acute phase anticipated approach assessment tools assessments assist clinical Clustering Clusters Community community settings consequence database death dual eligible exclusion criteria finding Google Scholar Government heterogeneity heterogenous identify include Inclusion Infection initial item Long management mental health Meta-analysis Novel coronavirus Patient peer-reviewed physical private sector proportion protocol R statistical software random effect referred to registration number reported Reporting review SARS-CoV-2 SARS-COV-2 infection Science Direct searched Study design Symptom Symptomatology synthesised systematic review to define Trial variety Web Web of Science [DOI] 10.1371/journal.pone.0266232 PMC 바로가기 [Article Type] Article
Gatekeeper training for vendors to reduce pesticide self-poisoning in rural South Asia: a study protocol for a stepped-wedge cluster randomised controlled trial남아시아 농촌 지역에서 살충제 중독을 줄이기 위한 공급업체를 위한 게이트키퍼 교육: 계단식 쐐기형 클러스터 무작위 통제 시험을 위한 연구 프로토콜Article Published on 2022-04-042022-09-11 Journal: BMJ Open [Category] Coronavirus, 임상, [키워드] 24 hours alcohol approved Asia Attempted suicide Cluster Committee conducted COVID-19 division divisions Edinburgh Effectiveness Ethics ethics committee evaluate faculty Faculty of Medicine form high risk hospital identify individual Intervention introduced kill Other outcome outcome measure outcome measures peer-reviewed pesticide pesticides poisoning Prevent Primary outcome public health random randomised controlled trial Randomised trial reduce registration number Research Ethics restriction Result review secondary Secondary outcomes self-harm South Study protocol Suicide suicide & Surveillance toxicology university [DOI] 10.1136/bmjopen-2021-054061 PMC 바로가기 [Article Type] Article