Possible Use of Phytochemicals for Recovery from COVID-19-Induced Anosmia and AgeusiaReview Published on 2021-08-182022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, MERS, SARS, [키워드] Ageusia Anosmia Anti-inflammatory Anti-inflammatory effects anti-viral effects can be used clinical settings Combination Compound compounds coronavirus COVID-19 develop diets disease essential oils expand IMPROVE Inflammatory less olfactory sense outbreak phytochemical phytochemicals plant SARS-CoV-2 selected shown Smell smell training Symptom taste training the SARS-CoV-2 unique worldwide pandemic [DOI] 10.3390/ijms22168912 PMC 바로가기 [Article Type] Review
Targeting phytoprotection in the COVID-19-induced lung damage and associated systemic effects—the evidence-based 3PM proposition to mitigate individual risksReview Published on 2021-08-032022-10-31 Journal: The EPMA Journal [Category] COVID-19, [키워드] affected aggression Anti-inflammation, Antibacterial Anti-inflammatory antioxidant antiviral properties Antiviral, COVID-19 applied ARDS Cancer Cancer, Chronic diseases Care chronic inflammation clinical utility Complication Coumarins COVID-19 COVID-19 infection Cytokine storm disease disease management Diseases disorder Effect effective Evidence flavonoids Health health condition Health economy Health policy healthcare Immunity individual Inflammation Isolation life-threatening lung damage Mental metabolic disorder mitigate neurologic obesity pandemic Pathologies Patient Periodontitis Personalized medicine phenolic acids Phenolic compounds phytochemicals Predictive Predictive preventive personalized medicine (3PM/PPPM) PROTECT reflected risk Risk assessment signaling pathways sleep quality smoking stilbenoids Stratification subgroup Support targeting Therapy efficacy vascular dysfunction [DOI] 10.1007/s13167-021-00249-y PMC 바로가기 [Article Type] Review
Phytochemicals present in Indian ginseng possess potential to inhibit SARS-CoV-2 virulence: A molecular docking and MD simulation study인도 인삼에 존재하는 파이토케미컬은 SARS-CoV-2 독성을 억제할 수 있는 잠재력을 가지고 있습니다: 분자 도킹 및 MD 시뮬레이션 연구Article Published on 2021-08-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 치료제, [키워드] active site Affect anti-SARS-CoV-2 Antiviral antiviral agent Antiviral agents binding characteristic complex Compound contagious coronavirus drug target effective effort exhibited glucoside In silico studies in vitro in vivo inhibit SARS-CoV-2 inhibitor inhibitory Lopinavir M pro M(pro) MD simulation molecular docking molecular docking studies Molecular docking study molecular dynamics nelfinavir pathogen Pathogens phytochemical phytochemicals protease Protein protein-ligand quercetin rutin rutinoside SARS-CoV-2 silico studies simulation studies Simulation study trajectory Withania somnifera withanolide [DOI] 10.1016/j.micpath.2021.104954 PMC 바로가기 [Article Type] Article
Plant-Based Phytochemical Screening by Targeting Main Protease of SARS-CoV-2 to Design Effective Potent InhibitorsArticle Published on 2021-06-262022-10-28 Journal: Biology [Category] COVID-19, [키워드] active site acute respiratory syndrome ADMET adverse effects Antiviral antiviral drug Asian binding affinity biological activity carcinogenicity caused Characteristics complex complexes compounds coronavirus coronavirus disease COVID-19 Cys145 deviation disease docked drug drug candidate dynamics simulation effective Efficacy exhibited expressed fluctuation gallate high mortality rate His41 in viral inhibitor Laboratory M pro molecular docking Molecular dynamics simulation pathway pharmacological phytochemical phytochemicals plant plants potent profile protease Protein radius of gyration Replication reported retrieved SARS-CoV-2 Screening simple Spread supported targeting thermal stability these compound Toxicity Transcription treat Treatment Vaccine viral infection was used were assessed worldwide pandemic [DOI] 10.3390/biology10070589 PMC 바로가기 [Article Type] Article
Food Containing Bioactive Flavonoids and Other Phenolic or Sulfur Phytochemicals With Antiviral Effect: Can We Design a Promising Diet Against COVID-19?Nutrition Published on 2021-06-172022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] activity Against alleviate anti-inflammatory action Antiviral approved Bioavailability Can complementary Containing contributing to coronavirus coronavirus disease country COVID-19 diet distribution drug flavanone flavonoid flavonol food Functional foods global pandemic Health Infectious disease information knowledge Laboratory mechanism molecular monoclonal antibodies Novel coronavirus Other pathogen Perspective phytochemical phytochemicals plant Prevent Research researcher SARS-CoV-2 Secondary Metabolite Spread sulfur Therapeutic approach therapeutic approaches therapy these compounds Vaccine viral infection viral pathology while [DOI] 10.3389/fnut.2021.661331 PMC 바로가기 [Article Type] Nutrition
Natural products and phytochemicals as potential anti‐SARS‐CoV ‐2 drugsReview Published on 2021-06-162023-07-01 Journal: Phytotherapy research : PTR [Category] SARS, [키워드] Coronaviruses COVID‐19 MERS‐CoV natural compounds phytochemicals prevention RNA‐Virus SARS‐CoV SARS‐CoV‐2 therapy [DOI] 10.1002/ptr.7151 PMC 바로가기 [Article Type] Review
Plant-derived chemicals as potential inhibitors of SARS-CoV-2 main protease (6LU7), a virtual screening studySARS-CoV-2 주요 프로테아제(6LU7)의 잠재적 억제제로서의 식물 유래 화학물질, 가상 스크리닝 연구Comparative Study Published on 2021-06-012022-09-11 Journal: Phytotherapy research : PTR [Category] Coronavirus, SARS, 치료제, [키워드] 3CLpro 6LU7 active site active sites ADMET antiviral activity antiviral properties antiviral property binding energy caused Compound compounds coronavirus disease Coronavirus disease 2019 COVID-19 cysteine cysteine protease dataset deaths docking Ebola Emetine enzyme Ginkgolide HIV Infection inhibitor inhibitors inhibitors of SARS-CoV-2 Lopinavir Mezerein molecular molecular docking MPro nelfinavir pharmacological physicochemical property phytochemicals protease SARS-CoV-2 shown Taking target Tubocurarine Virtual screening viruses Vitexin was performed was selected was used were used Zika [DOI] 10.1002/ptr.7041 PMC 바로가기 [Article Type] Comparative Study
Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of ActionsPharmacology Published on 2021-05-282022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] Action affecting Against Anti-COVID-19 Anti-infective anticancer therapies Antiviral antiviral properties approach approved Ayurved medicine bioactive metabolites clinical clinical trial conducted coronavirus COVID-19 develop drugs effective Efficacy eliminated global public health Herbal Hospitalization identify infective medications Medicine Medicines metabolite morbidity and mortality notable nutraceuticals pandemic phytochemicals Phytomedicine plant product reached researcher SARS-CoV-2 shown therapy Traditional Traditional Chinese medicine traditional Chinese medicines Vaccine Vaccines viral infection World Health Organization worldwide pandemic [DOI] 10.3389/fphar.2021.671498 PMC 바로가기 [Article Type] Pharmacology
Phytochemicals Targeting JAK–STAT Pathways in Inflammatory Bowel Disease: Insights from Animal ModelsReview Published on 2021-05-102024-09-02 Journal: Molecules [Category] 대상포진, [키워드] inflammatory bowel disease (IBD) janus kinase (JAK) phytochemicals signal transducer and activator of transcription (STAT) [DOI] 10.3390/molecules26092824 PMC 바로가기 [Article Type] Review
Phytochemicals from Plant Foods as Potential Source of Antiviral Agents: An OverviewReview Published on 2021-04-192022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] acute respiratory syndrome addition AIDS antiviral activities antiviral agent Antiviral agents antiviral drug antiviral drugs Bioavailability cause caused COVID-19 COVID-19 disease COVID-19 pandemic Critical defend delivery technologies described drug Ebola effective event Favipiravir flow diagram food Health Hepatitis HIV immunodeficiency IMPROVE in vitro include Inclusion Influenza virus interferon morbidity Mortality Older patients phytochemical phytochemicals plant plant foods Potential potential risk question Remdesivir Replication ribavirin Source syndrome Taking the disease the SARS-CoV-2 virus therapeutic these compound threat treated Treatment viral disease Viral diseases viral infections virus viruses was used widespread [DOI] 10.3390/ph14040381 PMC 바로가기 [Article Type] Review