Inferring the ecological niche of bat viruses closely related to SARS-CoV-2 using phylogeographic analyses of Rhinolophus speciesRhinolophus 종의 phylogeographic 분석을 사용하여 SARS-COV-2와 밀접한 관련된 BAT 바이러스의 생태 학적 틈새를 추론Article Published on 2021-07-122022-09-10 Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 치료기술, [키워드] acute respiratory syndrome coronavirus affected analysed Analysis Animal migration Asia bat bat virus bat viruses bat-CoV bats Biogeography China coronavirus coronavirus disease Coronavirus disease 2019 country COVID-19 COVID-19 pandemic Cytochrome C cytochrome c oxidase dispersal ecological Ecological modelling ecological niche ecological niches Evolutionary biology Evolutionary ecology genetic diversity genomic Haplotype haplotypes human population human populations humans include Infectious diseases less mainland Southeast Asia mitochondrial occur pandemic Pandemics Population Population genetics predicted Recombination Region reported reservoir reservoirs respiratory risk SARS-CoV SARS-CoV-2 SARS-CoV2 sequence severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 subunit Surveillance transitional zone viral infection virus viruses zone [DOI] 10.1038/s41598-021-93738-z PMC 바로가기 [Article Type] Article
Limited Predictability of Amino Acid Substitutions in Seasonal Influenza VirusesArticle Published on 2021-07-052023-06-08 Journal: Molecular Biology and Evolution [Category] Fulltext, 신종인플루엔자, [키워드] Evolution Influenza Population genetics [DOI] 10.1093/molbev/msab065 PMC 바로가기
Design of a FAIR digital data health infrastructure in Africa for COVID‐19 reporting and researchArticle Published on 2021-06-112022-10-28 Journal: Advanced Genetics (Hoboken, N.j.) [Category] COVID-19, [키워드] aggregate Algorithm Clinical data collected COVID‐19 Data science disease Ethical Genome Genotype Health health information incidence interoperability Kenya knowledge capture legal and social implications Liberia Medical informatics mutations network Nigeria organization Point point of care Population genetics producing raise Research SARS‐CoV‐2 social health care Support Treatment Uganda viral genomes Volume Zimbabwe [DOI] 10.1002/ggn2.10050 PMC 바로가기 [Article Type] Article
The major genetic risk factor for severe COVID-19 does not show any association among South Asian populations심각한 Covid-19의 주요 유전자 위험 인자는 남아시아 인구의 연관성을 나타내지 않습니다.Article Published on 2021-06-112022-09-01 Journal: Scientific Reports [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] ACE2 appear association Case fatality rate correlation COVID-19 dataset European Evidence Evolutionary genetics Fatality rate genetic loci genetic risk factor genomic greater Haplotype India Infection infection rate loci modulate molecular evolution Neanderthal polymorphism Population Population genetics populations recent responsible risk Risk factors severe COVID-19 severity South Asian susceptibility [DOI] 10.1038/s41598-021-91711-4 PMC 바로가기 [Article Type] Article
Unravelling population structure heterogeneity within the genome of the malaria vector Anopheles gambiae말라리아 매개체인 아노펠레스 감비아의 게놈 내 인구 구조 이질성 해소Research Article Published on 2021-06-082024-08-08 Journal: BMC Genomics [Category] 말라리아, [키워드] Chromosomal inversions malaria Population genetics T-SNE Visualization method whole-genome analysis [DOI] 10.1186/s12864-021-07722-y PMC 바로가기 [Article Type] Research Article
Association of Vitamin D, Zinc and Selenium Related Genetic Variants With COVID-19 Disease SeverityNutrition Published on 2021-06-042022-10-31 Journal: Frontiers in Nutrition [Category] COVID-19, [키워드] Adults allelic analyzed association Bioavailability carried carrier Clinical severity Comparative COVID-19 COVID-19 disease course COVID-19 pandemic COVID-19 patient CYP2R1 DHCR7 disease severity DMGDH European Frequency G allele Genetic variant Genotype Health implicated indicate indicated investigated Italian population lowest NADSYN1 nutrigenetics pediatric Pediatric patients Population Population genetic analysis Population genetics PPCDC profiles selected Selenium severe COVID-19 severe disease Spanish variant variants Variation VDR Vitamin D Zinc [DOI] 10.3389/fnut.2021.689419 PMC 바로가기 [Article Type] Nutrition
Genetic evidence for the association between COVID-19 epidemic severity and timing of non-pharmaceutical interventionsCOVID-19 전염병의 심각성과 비약물적 개입의 시기 간의 연관성에 대한 유전적 증거Article Published on 2021-04-122022-09-10 Journal: Nature Communications [Category] MERS, SARS, 유전자 메커니즘, 치료기술, [키워드] association carried COVID-19 COVID-19 epidemic cumulative death Effect Effectiveness elapsed Epidemic Epidemics Epidemiology estimate examined explain genetic evidence implementation Intervention Intervention effects less location lockdown measure morbidity and mortality National phylodynamic Phylogenetic analysis Phylogeny Population genetics Public health intervention reported SARS-CoV-2 SARS-CoV-2 sequence sequence severe COVID-19 severity the epidemic Travel variance Variation variations Viral whole genome [DOI] 10.1038/s41467-021-22366-y PMC 바로가기 [Article Type] Article
The Spike D614G mutation increases SARS-CoV-2 infection of multiple human cell typesSpike D614G 돌연변이는 여러 인간 세포 유형의 SARS-CoV-2 감염을 증가시킵니다Research Article Published on 2021-02-112022-09-10 Journal: eLife [Category] MERS, 변종, 유전자 메커니즘, [키워드] A549 ACE2 ACE2 receptor binding Caco-2 Calu Calu-3 cell Cell coronavirus COVID-19 D614G D614G mutation D614G variant effective epithelial cells expressing fold functional G614 variant genetics Huh7.5 Human human cell human cell lines human cells human lung human lung epithelial cells increase Lentiviral particle lentiviral particles Linkage disequilibrium mechanism Mutation ORF1b overexpressing Point mutation Population genetics Prevalence Protein proteolytic cleavage pseudotyped ranged SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus site-directed mutagenesis spike Spike protein surpassed the SARS-CoV-2 virus the Spike transducing variant variants virus wild-type [DOI] 10.7554/eLife.65365 PMC 바로가기 [Article Type] Research Article
Describing variability in pig genes involved in coronavirus infections for a One Health perspective in conservation of animal genetic resourcesArticle Published on 2021-02-092022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] ACE2 affected Agricultural genetics Animal breeding ANPEP Asian component Coronavirus infection Data mining described Describing Diseases DPP4 European example Genetic Genetic markers Genomics Host host gene host receptor Infection Infectious diseases investigated involved mechanisms Mild Next-generation sequencing one health Perspective Population Population genetics populations protein sequence proteinase reservoir resource resources risk TMPRSS2 Variability variant viral infections viral spike protein [DOI] 10.1038/s41598-021-82956-0 PMC 바로가기 [Article Type] Article
Population Genomics Insights into the First Wave of COVID-19Article Published on 2021-02-072022-10-29 Journal: International Review of Cell and Molecular Biology [Category] COVID-19, [키워드] Analysis Asian cohorts contributed coronavirus coronavirus genome COVID-19 demographic inference European event Evidence Evolution of SARS-CoV-2 First wave genetics Genome genomic region Genomics growth Host hosts human SARS-CoV-2 insight mechanisms Mutation mutation rate occurred pandemic parameter polymorphism Population Population genetics Positive selection Recombination recombination event Region SARS-coronavirus SARS-CoV-2 SARS-CoV-2 genomes selective sweeps Support target the Betacoronavirus the SARS-CoV-2 the SARS-CoV-2 genome took place Wave [DOI] 10.3390/life11020129 PMC 바로가기 [Article Type] Article