Psychiatric genomics research during the COVID-19 pandemic: A survey of Psychiatric Genomics Consortium researchers코로나19 팬데믹 기간 동안의 정신의학 유전체 연구: 정신의학 유전체학 컨소시엄 연구원을 대상으로 한 설문조사Article Published on 2021-01-012022-09-11 Journal: American journal of medical genetics. Part B, Neur [Category] 유전자 메커니즘, [키워드] academic medicine concern conducted COVID-19 COVID-19 pandemic faculty female funding genders Genomics individual investigator investigators organization organizations pandemic PGC progression promotion promotion. provided Quantitative reported representing Research researcher researchers responses Result trainee women [DOI] 10.1002/ajmg.b.32838 PMC 바로가기 [Article Type] Article
COVID-19–Related Disruptions and Increased mHealth Emergency Use Intention: Experience Sampling Method StudyOriginal Paper Published on 2020-12-302022-10-31 Journal: JMIR mHealth and uHealth [Category] COVID-19, MERS, [키워드] 95% CI Activation addition amplified Analysis caused China cognitive collected country COVID-19 COVID-19 pandemic COVID-19–induced strain defined Disruption Drawing Emergency Emergency use emergency use intention event disruption experience Factor fluctuation global public health Health healthy help Hierarchical Home isolation Increased individual influence information Intention investigated linear modeling maintain mechanism Mental mental health mHealth Mobile health mobile health services objective promotion promotion regulatory focus Psychological raised Regulatory Research researcher Result sampling Stress Symptom urgent medical care [DOI] 10.2196/20642 PMC 바로가기 [Article Type] Original Paper
Promotion of Physical Activity in Older People Using mHealth and eHealth Technologies: Rapid Review of ReviewsReview Published on 2020-12-292022-10-30 Journal: Journal of Medical Internet Research [Category] Coronavirus, MERS, SARS, [키워드] Abstract accelerometer activity app approach Characteristics CINAHL component conducted COVID-19 COVID-19 pandemic effective Effectiveness eHealth eHealth technology eligibility engage English language event Evidence excluded Health include inclusion criteria Inconclusive increased risk independent Initially Intervention item mHealth Mobile moderate objective offer Older Pedometer physical physical activity physically promotion Rapid reduced Reporting Result review screened searched social distancing Support systematic review technology title Transmission were assessed [DOI] 10.2196/22201 PMC 바로가기 [Article Type] Review
Peripheral Blood Immune Profiling of Convalescent Plasma Donors Reveals Alterations in Specific Immune Subpopulations Even at 2 Months Post SARS-CoV-2 Infection회복기 혈장 기증자의 말초혈액 면역 프로파일링은 SARS-CoV-2 감염 후 2개월에도 특정 면역 하위 집단의 변화를 보여줍니다Article Published on 2020-12-252022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, [키워드] alteration analyzed antibody B cells Blood cause CD16 CD4 CD56 CD8 characterized control subject control subjects convalescent plasma convalescent plasma donors COVID-19 COVID-19 patients deficiency Donor donors Exhaustion Follow-up full recovery Granulocytes highest Hospitalized Humoral immunity immune cells Immune profile immune profiling immune system lowest lymphocyte Lymphocytes lymphopenia Monocytes Month multiparametric flow cytometry natural killer NKT cells patients with COVID-19 peripheral Peripheral blood phenotype pro-inflammatory monocytes pro-inflammatory response Profiling promotion reduced regulatory T cells restored SARS-CoV-2 serum shown Specific subpopulations T and B cells T cells Th17 cells Th2 [DOI] 10.3390/v13010026 PMC 바로가기 [Article Type] Article
SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cellsSARS-CoV-2 스파이크 단백질은 상피 세포에서 지오텐신 II 수용체 신호 전달의 활성화에 의해 IL-6 트랜스 신호 전달을 촉진합니다Research Article Published on 2020-12-072022-08-13 Journal: PLoS Pathogens [Category] Biology and Life Sciences, MERS, SARS, 진단, [키워드] ACE2 ACE2 expression Activation acute respiratory distress acute respiratory distress syndrome ADAM Aggressive angiotensin angiotensin converting enzyme Angiotensin converting enzyme-2 Angiotensin II AP-1 AT1 Author c-Fos candesartan Candesartan cilexetil cascade Cell cell interactions cells Characteristics chemokines classical combating coordination Coronavirus infection COVID-19 COVID-19 disease COVID-19 disease severity culture supernatant cytokine cytokine response Cytokine storm Cytokines disease severity down-regulation ectopic expression elevated endothelial Endothelial cell epithelial epithelial cell epithelial cells excessive inflammatory response expressed expressing expression Extracellular generate Host human epithelial cell human epithelial cells human liver hyper-inflammatory response IL-6 IL-6R indicated induce inducer Infection Inflammatory cytokine inhibit inhibited Interaction leads Lung epithelial cells Lung injury Macrophage macrophage activation macrophages MAPK MCP-1 mechanism mediators Monocytes monocytes/macrophage monocytes/macrophages Multi-organ damage NF-κB observation pathology pathway patient sera Phosphorylation primary host pro-inflammatory promote promoted promotion protease protein expression pulmonary epithelial cell receptor receptor antagonist receptor protein receptor signaling referred to Regulatory residue respiratory distress Respiratory distress syndrome SARS Coronavirus SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 spike SARS-CoV-2 spike protein secretion Signaling SOCS3 soluble IL-6R Spike protein STAT3 suggested syndrome therapeutic therapeutic intervention tissue damage trans trans-signaling transcriptional transmembrane vascular endothelial cell Viral viral infection viral spike protein with COVID-19 [DOI] 10.1371/journal.ppat.1009128 PMC 바로가기 [Article Type] Research Article
Risk Factors and Mental Health Promotion Strategies in Children During COVID-19Public Health Published on 2020-10-152022-10-31 Journal: Frontiers in Public Health [Category] Coronavirus, MERS, SARS, [키워드] children COVID-19 COVID19 Factor mental health promotion Risk factors Strategies Strategy [DOI] 10.3389/fpubh.2020.580720 PMC 바로가기 [Article Type] Public Health
Behavioral and sociodemographic predictors of anxiety and depression in patients under epidemiological surveillance for COVID-19 in EcuadorResearch Article Published on 2020-09-302022-10-28 Journal: PLoS ONE [Category] Coronavirus, MERS, SARS, [키워드] affected Analysis Anxiety anxiety symptom association being collected complications Corona country COVID-19 COVID-19 patient cross-sectional Depression depressive symptom Ecuador epidemiological explained Gender Generalized Health highest identify indicated Latin America less mandatory mental health mental health problem moderate Mortality pandemic Patient patients with COVID-19 predictor promotion Psychiatric Psychological state questionnaire Regression Risk factors Self-isolation severe symptom severity socio-demographic information Sociodemographic Surveillance understanding variable was performed [DOI] 10.1371/journal.pone.0240008 PMC 바로가기 [Article Type] Research Article
Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion StrategyReview Published on 2020-08-132022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, [키워드] assist Behaviour change build communication Consensus country COVID-19 COVID-19 pandemic COVID-19 vaccination COVID-19 vaccine Critical Developing effective ENhance Government group Guidance guideline information pandemic Population promotion recommendation reduce responsible social marketing Strategy uptake vaccination Vaccine vaccine availability Vaccine hesitancy Vaccine uptake Vaccines [DOI] 10.3390/ijerph17165893 PMC 바로가기 [Article Type] Review
Physical Activity, Screen Time, and Emotional Well-Being during the 2019 Novel Coronavirus Outbreak in ChinaArticle Published on 2020-07-172022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] 95% CI activity adopted Affect ANOVA China Chinese collected confirmed COVID-19 case correlation COVID-19 COVID-19 outbreak emotional evaluate the effect Health help IMPROVE individual initial less lockdown novel pandemic participant per day physical activity positive Prevalence promotion proportion psychological Impact questionnaire recall Screen screen time sedentary lifestyle Spearman’s correlation coefficient statistical analysis time were used [DOI] 10.3390/ijerph17145170 PMC 바로가기 [Article Type] Article
Breath Regulation and yogic Exercise An online Therapy for calm and Happiness (BREATH) for frontline hospital and long-term care home staff managing the COVID-19 pandemic: A structured summary of a study protocol for a feasibility study for a randomised controlled trial호흡 조절 및 요가 운동 COVID-19 대유행을 관리하는 최전선 병원 및 장기 요양원 직원을 위한 평온과 행복을 위한 온라인 치료(BREATH): 무작위 대조 시험에 대한 타당성 연구를 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-07-142022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 active treatment All study participant All study participants allocation concealment Analysis Anxiety ARMS blinded Blinding breath breaths Canada Care collected Complete Completeness completion consent form control arm Controlled trial COVID-19 COVID-19 pandemic COVID-19 patient data entry Depression determine dissemination element eligibility English enhancement exercise feasibility feasible foundation Group allocation Health Health promotion Healthcare staff healthcare worker Healthcare workers healthy hospital IMPROVE include Insomnia interactive module Intervention involved London Long-term care management measure medium mental health mind-body intervention mindfulness Mindfulness-based muscle relaxation music therapy number objective offered online session Open-label outcome participant phase Phase I physical Prevent Program progressive muscle relaxation promotion protocol Psychoeducation randomised randomised controlled trial randomization randomize Randomized Randomized controlled trial RCT recruited recruitment REDCap reduce Research researcher Resilience resiliency retention Sample size scheduling significantly status study hypothese study hypotheses Study protocol subsequent supervision therapy Treatment Trial USA website Weekly windows Work stress yoga [DOI] 10.1186/s13063-020-04583-w PMC 바로가기 [Article Type] Letter