Efficacy of Qingfei Paidu Decoction on Patients with COVID-19 Pneumonia in Wuhan, China: A Propensity Score Matching StudyResearch Article Published on 2021-10-052022-10-31 Journal: Evidence-based Complementary and Alternative Medicine : eCAM [Category] COVID-19, [키워드] Administered Analysis Chinese cohorts Combination Coronavirus 2019 COVID-19 criteria death Decoction develop diagnosis of COVID-19 Diseases Effect effective Efficacy eligible participant enrolled febrile global effort groups hazard ratio Hypothesis identify Laboratory matching packaged pandemic participant Patient patients died patients with COVID-19 Pneumonia Primary outcome Propensity score PSM receive reduce Result retrospective risk of death score significantly significantly lower single-center survival TCM treat Treatment Union Hospital was used with COVID-19 Wuhan Wuhan, China [DOI] 10.1155/2021/4303380 PMC 바로가기 [Article Type] Research Article
SARS-CoV-2 Vaccine Effectiveness in a High-Risk National Population in a Real-World Setting실제 환경에서 고위험 인구의 SARS-CoV-2 백신 효과Article Published on 2021-10-012022-09-11 Journal: Annals of internal medicine [Category] SARS, 변종, [키워드] 95% CI Affair age BNT-162b2 body mass body mass index Care case-control study Comorbidities Department determine disease severity effective Effectiveness Emergency use authorization evaluate Follow-up Health Health care Health care system high-risk population Infection lack Logistic regression male median age Moderna Moderna mRNA-1273 vaccine Mortality mRNA-1273 Participants Pfizer Pfizer-BioNTech Population positive presence of comorbidities Propensity score remained routine clinical care SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccination SARS-CoV-2 variant SARS-CoV-2 variants second dose setting Sex tested the median vaccination Vaccine veteran white [DOI] 10.7326/M21-1577 PMC 바로가기 [Article Type] Article
Baricitinib reduces 30-day mortality in older adults with moderate-to-severe COVID-19 pneumoniaBaricitinib은 중등도에서 중증의 COVID-19 폐렴을 앓고 있는 노인의 30일 사망률을 감소시킵니다.Observational Study Published on 2021-10-012022-09-11 Journal: Journal of the American Geriatrics Society [Category] SARS, 임상, 치료제, [키워드] 30-Day mortality 95% CI adjusted Adults age Analysis analyzed Baricitinib Cohort cohort study cohorts controls COVID-19 COVID-19 pneumonia death Effect Efficacy Fatality rate female highest Hospitalized IMPROVE Kaplan-Meier moderate-to-severe COVID-19 pneumonia Mortality mortality rate mortality risk Older older adult Older adults outcome Patient patients Pneumonia Propensity score reduce reduction reduction in retrospective cohort study risk severe disease severe pneumonia shown stratified with COVID-19 [DOI] 10.1111/jgs.17357 PMC 바로가기 [Article Type] Observational Study
Circulating MR-proADM levels, as an indicator of endothelial dysfunction, for early risk stratification of mid-term mortality in COVID-19 patientsCOVID-19 환자의 중기 사망률에 대한 조기 위험 계층화를 위한 순환 MR-proADM 수준, 내피 기능 장애의 지표Observational Study Published on 2021-10-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 바이오마커, 임상, [키워드] adrenomedullin Analysis assist association AUC Biomarker blood sample Coagulopathy complex interaction confounders contribute COVID-19 COVID-19 patient COVID-19 patients Cox regression Cutoff emergency department endothelial damage Endothelial dysfunction endotheliopathy Endpoint enrolled evaluated increased mortality independent Laboratory Laboratory test mid-regional proadrenomedullin Mortality mortality rate MR-proADM Negative predictive value observational study Patient physician Predictive value primary endpoint Prognosis Propensity score reported resulting risk stratification ROC AUC SARS-CoV-2 second wave sensitivity severity specificity surrogate thrombocytopathy Thromboinflammation were used [DOI] 10.1016/j.ijid.2021.08.058 PMC 바로가기 [Article Type] Observational Study
Antifungal prophylaxis for prevention of COVID-19-associated pulmonary aspergillosis in critically ill patients: an observational studyObservational Study Published on 2021-09-152022-10-04 Journal: Critical Care [Category] 임상, [키워드] 95% CI animal Antifungal ARF baseline characteristics CAPA clinical outcomes Complication consecutive patient Consensus Controlled trial coronavirus disease 19 COVID-19-associated aspergillosis criteria Critically ill diagnosed Efficacy and safety estimate European evaluate fungal hazard ratio Human ICU ICU admission ICU patient incidence intensive care unit median Mortality mould Mould prophylaxis mycology Mycose no difference Patient patients Posaconazole Prevent Primary outcome Propensity score Prophylaxis reduced Respiratory failure Result secondary outcome significantly Society supplementary material survival translate was performed were recorded with COVID-19 [DOI] 10.1186/s13054-021-03753-9 PMC 바로가기 [Article Type] Observational Study
Efficacy and safety of direct-acting oral anticoagulants compared to vitamin K antagonists in COVID-19 outpatients with cardiometabolic diseasesOriginal Investigation Published on 2021-09-042022-10-31 Journal: Cardiovascular Diabetology [Category] COVID-19, [키워드] 95% confidence interval all-cause mortality antagonist Anticoagulant bleeding cardiometabolic disease cardiometabolic diseases circulatory system clinical Cohort conducted Coronavirus disease 2019 COVID-19 diagnosis COVID-19 outpatient demonstrated Diabetes Mellitus direct-acting Direct-acting oral anticoagulant Direct-acting oral anticoagulants disease DOAC DOACs hazard ratio Health ICU Impact intensive care lower risk Multimorbidity OAC oral anticoagulant outcome outcomes Outpatient Patient Primary outcome Prognosis Propensity score PSM receiving remained remains uncertain Research Result risk SARS-CoV-2 supplementary material survival therapy thrombosis thrombotic treated venous Ventilation vitamin K antagonist VKA was used [DOI] 10.1186/s12933-021-01368-6 PMC 바로가기 [Article Type] Original Investigation
Hospital mortality in COVID-19 patients in Belgium treated with statins, ACE inhibitors and/or ARBsObservational Study Published on 2021-09-022022-10-05 Journal: Human vaccines & immunotherapeutics [Category] SARS, 임상, [키워드] 28-day mortality 95% CI ACE ACE inhibitor ACE inhibitors ACEIs activity angiotensin receptor blocker Angiotensin receptor blockers ARB ARBs Belgium Case-control characterized clinical trial Combination combination treatment COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients determine drug Endothelial cell Endothelial dysfunction help hospital Hospital mortality hospitalized COVID-19 patients immunometabolism IMPROVE In-hospital maintain Mortality observational study pathogenesis of COVID-19 Propensity score receptor reduced reduction in statins survival treated Treatment unlikely Vaccine [DOI] 10.1080/21645515.2021.1920271 PMC 바로가기 [Article Type] Observational Study
Metformin use is associated with a reduced risk of mortality in patients with diabetes hospitalised for COVID-19Observational Study Published on 2021-09-012022-10-05 Journal: Diabetes & metabolism [Category] 임상, [키워드] addressed Admission Anti-inflammatory applied approach association complications COVID-19 death diabetes Diabetic feature French had more hospitalised immunosuppressive effects intubation Kaplan-Meier survival curve Logistic regression analysis lower risk Mechanical mechanical ventilation metformin Mortality mortality rate occurred Odds ratio outcome Patient patients with diabete Prevalence primary endpoint Primary outcome Probability Prognosis Propensity score reduced risk reported tracheal Treatment Type type 2 diabete type 2 diabetes Weighting [DOI] 10.1016/j.diabet.2020.101216 PMC 바로가기 [Article Type] Observational Study
Psychosomatic Rehabilitation Patients and the General Population During COVID-19: Online Cross-sectional and Longitudinal Study of Digital Trainings and Rehabilitation EffectsOriginal Paper Published on 2021-08-262022-10-31 Journal: JMIR Mental Health [Category] COVID-19, [키워드] affected Anxiety assessments Care clinics component conducted contribute COVID-19 COVID-19 pandemic cross-sectional Depression Digital disorder Effect evaluated Exploratory factor analysis face-to-face therapy Factors General population Germany greater Health help Hierarchical individual Intention internet-delivered digital trainings investigated Level lockdown loneliness longitudinal Making measure Medical rehabilitation mental health Multivariate analysis objective offered Participation Patient Perceived stress performed platform Population professional Propensity score Psychological well-being psychosomatic psychosomatic rehabilitation questionnaire Registration regression analysis rehabilitation rehabilitation patient reported Research Result Satisfaction Stress stressors Support Symptom symptoms of depression therapy Topic training Treatment were used [DOI] 10.2196/30610 PMC 바로가기 [Article Type] Original Paper
Impact of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on the Inflammatory Response and Viral Clearance in COVID-19 PatientsCardiovascular Medicine Published on 2021-08-192022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] ACE inhibitor ACEIs angiotensin angiotensin receptor blocker angiotensin-converting enzyme inhibitor Antiviral treatment ARB ARBs assigned association blocker confounders control group coronavirus disease COVID-19 COVID-19 mortality current decrease Decreased elevated evaluate Evidence Hospitalization hypertension IL-10 IL-1β IL-6 IL-8 Impact Inflammatory response introduced Lymphocyte count medication multicenter Patient patients plasma proinflammatory cytokines Propensity score response retrospective cohort study TNF-α Treatment viral clearance viral shedding withdrawn [DOI] 10.3389/fcvm.2021.710946 PMC 바로가기 [Article Type] Cardiovascular Medicine