Case Report: Remdesivir and Convalescent Plasma in a Newly Acute B Lymphoblastic Leukemia Diagnosis With Concomitant Sars-CoV-2 InfectionPediatrics Published on 2021-08-022022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] accelerate Acute lymphoblastic leukemia adverse event age antiviral therapy Blood Bone marrow Cancer Chest clinical conditions Concomitant convalescent plasma COVID-19 diagnosed Diagnosis disease female Fever Hypothesis Immunosuppressive treatment Infection infections leukemia malignancies management moderate molecular analysis Morphological neutropenia oncology patients Patient pediatric Prognosis pulmonary involvement Remdesevir required risk SARS-CoV-2 detection SARS-COV-2 infection SARS–CoV−2 severe SARS-CoV-2 Spread stability therapy Treatment worsened [DOI] 10.3389/fped.2021.712603 PMC 바로가기 [Article Type] Pediatrics
Analysis of endogenous oxidative damage markers and association with pulmonary involvement severity in patients with SARS-CoV-2 pneumoniaSARS-CoV-2 폐렴 환자에서 내인성 산화 손상 표지자 및 폐 침범 중증도와의 연관성 분석Article Published on 2021-08-012022-09-11 Journal: Infectious diseases now [Category] MERS, 바이오마커, [키워드] Affect albumin albumin level association caused coenzyme Q10 control group CoQ10 COVID-19 CRP levels determined by ELISA assay ferritin healthy control healthy volunteers high-pressure liquid chromatography Inflammation Ischemia Liquid chromatography Lungs malondialdehyde marker MDA nicotinamide no significant difference NOX4 organs oxidative damage parameter Patient patients with pneumonia patients with SARS-CoV-2 Pneumonia positively correlated pulmonary involvement SARS-CoV-2 SARS-CoV-2 pneumonia SARS-CoV-2 virus severe pulmonary involvement severity significant difference significantly significantly higher widespread [DOI] 10.1016/j.idnow.2021.06.302 PMC 바로가기 [Article Type] Article
Prevalence and significance of pulmonary disease on lung ultrasonography in outpatients with SARS-CoV-2 infectionSARS-CoV-2 감염 외래 환자의 폐 초음파 검사에서 폐질환의 유병률과 중요성Article Published on 2021-08-012022-09-11 Journal: BMJ Open Respiratory Research [Category] 치료기술, [키워드] adverse outcomes Analysis broad spectrum Clinical outcome clinical outcomes Clinical significance Cohort Comorbidities Comorbidity consolidations correlated correlations COVID-19 COVID-19 pneumonia demographics diagnosed died evaluated hospitalised identify identifying imaging/CT MRI etc Infection interstitial pneumonia lack lung majority mechanical ventilation MRI Multivariate analysis natural history Outpatient outpatients Patient Patient symptoms patients with SARS-CoV-2 Pneumonia positive Prevalence pulmonary disease pulmonary involvement required risk stratification SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 PCR Severity Score Shortness of breath subset were assessed [DOI] 10.1136/bmjresp-2021-000947 PMC 바로가기 [Article Type] Article
Prediction of COVID-19 deterioration in high-risk patients at diagnosis: an early warning score for advanced COVID-19 developed by machine learningOriginal Paper Published on 2021-07-192022-10-29 Journal: Infection [Category] COVID-19, COVID19(2023년), SARS, [키워드] Acute kidney injury Advanced stage age AUC baseline body mass index clinical Complicated stage Contact COVID-19 CRP dataset Deterioration Diagnosis Dyspnea Early warning score European high-risk patient Hospitalization identifying Inflammation LDH LEOSS lymphocyte counts machine learning medical intervention Mild multicenter oxygen saturation parameter Patient patients prediction Predictive Predictive model pulmonary involvement Result risk SARS-CoV-2 SARS-CoV-2 positive patient score selected smoking supplementary material survey temperature training dataset translated Treatment validation cohort variable variables were used while [DOI] 10.1007/s15010-021-01656-z PMC 바로가기 [Article Type] Original Paper
Factors Predicting Outcome in Intensive Care Unit-Admitted COVID-19 Patients: Using Clinical, Laboratory, and Radiologic CharacteristicsResearch Article Published on 2021-07-072022-10-31 Journal: Critical Care Research and Practice [Category] COVID-19, [키워드] Accuracy advanced age age Analysis analyzed chest CT scan clinical Combination contributing to coronavirus disease COVID-19 COVID-19 patient COVID-19 patients crazy-paving pattern death Diastolic blood pressure enrolled evaluated extension Factor Factors GGO ground-glass opacity hypertension ICU intensive care Laboratory Logistic regression lower lobe male medical record Mortality mortality rate no significant difference nonsurvivor nonsurvivors not significantly different parenchymal Patient Positive predictive value predict prevalent Prognostic value pulmonary involvement radiologic remained Result sensitivity significantly more specificity survived survivor the patient two subgroup underlying diseases vital signs [DOI] 10.1155/2021/9941570 PMC 바로가기 [Article Type] Research Article
Assessment of interobserver reliability and predictive values of CT semiquantitative and severity scores in COVID lung diseaseResearch Published on 2021-06-182022-10-31 Journal: The Egyptian Journal of Radiology and Nuclear Medicine [Category] COVID-19, [키워드] acute respiratory syndrome assessment caused Clinical outcome coronavirus coronavirus disease correlation COVID COVID pneumonia COVID-19 cross-sectional Cutoff global pandemic HRCT ICC individuals initial interstitial pneumonia Lung disease lung involvement morbidity organ oxygen Pneumonia Positive predictive value Predictive progressed pulmonary involvement pulmonary system radiological reliability reported Result SARS-CoV-2 score severe disease severity Severity of infection Severity Score similarity statistical subsequent tomography virus Wuhan, China [DOI] 10.1186/s43055-021-00523-z PMC 바로가기 [Article Type] Research
Targeted Mitochondrial Therapy With Over-Expressed MAVS Protein From Mesenchymal Stem Cells: A New Therapeutic Approach for COVID-19Cell and Developmental Biology Published on 2021-06-112022-10-31 Journal: Frontiers in Cell and Developmental Biology [Category] COVID-19, [키워드] ACE2 addition affecting approach cause Cell cellular cellular immunity COVID-19 damaged cell damaged tissue disease Diseases element expression expression of SARS-CoV-2 healthy host cell IFN immune immune response Impaired IMPROVE induce Inflammation innate immune response innate immune responses innate immune system interferon Ligand MAVS mesenchymal stem cell Mitochondria mitochondrial mitochondrial antiviral-signaling protein MSC MSCs New outer membrane pathogenesis of COVID-19 Probability Protein pulmonary involvement reduce regenerative regulate Regulatory rejection Replication S protein SARS-CoV-2 STEM stem cell Stress Symptom the SARS-CoV-2 these cell tissue inflammation transferring Transport viable treatment viral spike protein virus [DOI] 10.3389/fcell.2021.695362 PMC 바로가기 [Article Type] Cell and Developmental Biology
Long-Term Pulmonary Damage From SARS-CoV-2 in an Infant With Brief Unexplained Resolved Events: A Case ReportMedicine Published on 2021-06-112022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] acute respiratory syndrome administration age breathing Chest computed tomography coronavirus COVID-19 COVID-19 infection damage died distress Fever FIVE Follow-up healthy Hospital admission Hospitalized Infant infected with SARS-CoV-2 Inhaled lack lung involvement mild respiratory mother Nasopharyngeal swab Newborn over oxygen Pneumonia positive pulmonary pulmonary complication pulmonary involvement report required resolved respiratory symptom SARS-CoV-2 SARS-CoV-2 pneumonia severe pneumonia sleep disorders tested weakness [DOI] 10.3389/fmed.2021.646837 PMC 바로가기 [Article Type] Medicine
Automatic algorithm for quantifying lung involvement in patients with chronic obstructive pulmonary disease, infection with SARS-CoV-2, paracoccidioidomycosis and no lung disease patients만성 폐쇄성 폐질환, SARS-CoV-2 감염, 파라콕시디오이데스진균증 및 폐 질환이 없는 환자의 폐 침범을 정량화하기 위한 자동 알고리즘Research Article Published on 2021-06-102022-09-12 Journal: PLoS ONE [Category] MERS, SARS, 진단, [키워드] Algorithm applied approach Automatic chronic obstructive chronic obstructive pulmonary disease Computed tomography contribute demonstrated develop diagnosed different diseases emphysema Entire lung fibrosis Ground-glass opacities high resolution impairment Infection infection with SARS-CoV-2 inflammatory process lung Lung disease Lung diseases lung involvement obstructive pulmonary disease paracoccidioidomycosis Patient patients Physicians prognostic provide pulmonary disease pulmonary involvement quantification Result SARS-CoV-2 Support Total lung volume Volume [DOI] 10.1371/journal.pone.0251783 PMC 바로가기 [Article Type] Research Article
Phase 2 randomized study on chloroquine, hydroxychloroquine or ivermectin in hospitalized patients with severe manifestations of SARS-CoV-2 infectionClinical Trial Published on 2021-06-012022-10-05 Journal: Pathogens and global health [Category] 임상, [키워드] addition Admission age Antibiotics Anticoagulant approved Brazil caused Chloroquine coronavirus Corticosteroid COVID-19 death diabetes double-blind drug drugs Effectiveness Efficacy Endpoint form groups HCQ Hospital admission hospitalized patient Hydroxychloroquine ICU ICU admission incidence independent independent risk factor invasive ventilation IRB Ivermectin male manifestation Mortality no difference not reduce obesity objective Older pandemic participant Patient patients patients hospitalized performed Phase 2 Phase 2 study Physicians predictor pulmonary involvement Randomized randomized study reference Result safety profile SARS-COV-2 infection Serious Adverse Event supplemental oxygen tested three group [DOI] 10.1080/20477724.2021.1890887 PMC 바로가기 [Article Type] Clinical Trial