Mucosal Immunization with DTaP Confers Protection against Bordetella pertussis Infection and Cough in Sprague-Dawley RatsDTaP를 이용한 점막 예방접종은 Sprague-Dawley 쥐의 Bordetella pertussis 감염 및 기침에 대한 보호를 제공합니다Article Published on 2021-09-132024-07-28 Journal: Infection and Immunity [Category] 백일해, 파상풍, [키워드] Bordetella pertussis DTaP immunization mucosal pertussis Plethysmography RATs [DOI] 10.1128/IAI.00346-21 PMC 바로가기
Sensitivity of Rapid Antigen Testing and RT-PCR Performed on Nasopharyngeal Swabs versus Saliva Samples in COVID-19 Hospitalized Patients: Results of a Prospective Comparative Trial (RESTART)Article Published on 2021-09-092022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] Antigen applied approach assays Basel biosensor collected Comparative conducted COVID-19 COVID-19 diagnosis Diagnosis diagnostic duration of symptom exhibited help Hospitalized hospitalized patient hospitalized patients intensive care investigated IQR mitigate much lower nasopharyngeal Nasopharyngeal swab Non-invasive Patient Prospective prospective observational study Rapid rapid antigen test rapid antigen testing RAT RATs Result RT-PCR RT-PCR testing Saliva salivary Sample SARS-CoV-2 SARS-CoV-2 diagnosis sensitivity shortage of reagent specificity specimen Standard Q step Swab swabs Switzerland Test Testing the median Viral transport medium VTM was used [DOI] 10.3390/microorganisms9091910 PMC 바로가기 [Article Type] Article
SARS-CoV-2 and regular patient treatment – from the use of rapid antigen testing up to treatment specific precaution measuresSARS-CoV-2 및 정기적인 환자 치료 – 신속한 항원 검사 사용부터 치료별 예방 조치까지Research Published on 2021-09-042022-09-10 Journal: Head & Face Medicine [Category] 변종, [키워드] activity addition aerosol Aerosols Analysis Antigen Care clinics Combination COVID-19 COVID-19 pandemic dental practice Dental Treatment dentist dentistry determine doctor droplet droplets equipment identify implementation involved maintain measure Patient patient treatment Precaution Rapid Rapid antigen tests RAT RATs recommendation Research Result risk SARS-CoV-2 Task Force Test transmission of SARS-CoV-2 Treatment variant [DOI] 10.1186/s13005-021-00289-9 PMC 바로가기 [Article Type] Research
Rapid Test Ag 2019-nCoV (PROGNOSIS, BIOTECH, Larissa, Greece); Performance Evaluation in Hospital Setting with Real Time RT-PCRRapid Test Ag 2019-nCoV(PROGNOSIS, BIOTECH, Larissa, Greece); Real Time RT-PCR을 통한 병원 환경에서의 성능 평가Brief Report Published on 2021-08-302022-09-10 Journal: International Journal of Environmental Research an [Category] MERS, SARS, 치료기술, 치료법, [키워드] 2019-nCoV Accuracy analyzed Antigen Chain Reaction clinical setting Concentration correlation demonstrated faster Genome Greece immunochromatography individual limit of detection Mass screening Nasopharyngeal samples nCoV nucleic acid nucleic acid amplification nucleic acid amplification tests nucleocapsid protein performance point of care polymerase chain polymerase chain reaction positive sample Positive test Prognosis Quantitative quantitative polymerase chain reaction R 2 Rapid rapid antigen test Rapid antigen tests Rapid test RATs regression analysis RT-PCR RT-qPCR SARS-CoV-2 SARS-CoV-2 detection sensitivity setting specificity Test test strips time Viral Viral antigen Viral load [DOI] 10.3390/ijerph18179151 PMC 바로가기 [Article Type] Brief Report
Negative SARS-CoV-2 PCR or rapid antigen test result and the subsequent risk of being infectious: a mathematical simulation studyResearch Article Published on 2021-08-102022-10-28 Journal: BMC Medical Research Methodology [Category] COVID-19, Fulltext, MERS, SARS, [키워드] Antigen applied approach Asymptomatic asymptomatic infection asymptomatic transmission comparable conducted Critical cumulative described determine expected False negative rate groups highlight identify incidence increase in individual individuals infectiousness mathematical negative Negative diagnostic tests negative test occur parameter PCR PCR test polymerase chain Population pre-symptomatic predicted proportion random RAT RATs reduced representing Result risk SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 test SARS-CoV-2 transmission screened Simulation subsequent supplementary material tested Variation [DOI] 10.1186/s12874-021-01361-3 PMC 바로가기 [Article Type] Research Article
Optimizing testing for COVID-19 in India인도에서 COVID-19에 대한 테스트 최적화Research Article Published on 2021-07-222022-09-12 Journal: PLoS Computational Biology [Category] SARS, 진단, [키워드] accompanied Antigen comparable condition COVID-19 COVID-19 test COVID-19 testing COVID-19 tests Effectiveness epidemiological fraction India Infection Intervention Isolation Laboratory less much higher outcome outlined PCR tests per day point-of-care positive proceed proportion provided Rapid rapid antigen test Rapid antigen tests Rapid test RAT RATs reduction in reverse-transcriptase polymerase-chain-reaction RT-PCR RT-PCR test RT-PCR tests sensitivity Sensitivity and specificity Test tested [DOI] 10.1371/journal.pcbi.1009126 PMC 바로가기 [Article Type] Research Article
Can pharmaceutical drugs used to treat Covid-19 infection leads to human health risk? A hypothetical study to identify potential riskCovid-19 감염을 치료하는 데 사용되는 제약 약물이 인간 건강 위험으로 이어질 수 있습니까?잠재적 위험을 식별하기위한 가상의 연구Article Published on 2021-07-152022-08-31 Journal: The Science of the total environment [Category] SARS, 신약개발, 치료제, [키워드] acceptable daily intake activity adverse effect adverse effects affected Analysis approach aquatic environment assumption calculate Can carried Chloroquine Concentration Consumption contaminant contaminated surface COVID-19 COVID-19 infection COVID-19 pandemic determine drug drugs Effect estimate estimates evaluated expected Health hypothetical identify indicated Infection ingestion Lopinavir lopinavir + ritonavir maximum minimum mixture NOAEL novel Novel coronavirus pandemic PECs pharmaceutical Pharmaceuticals potential risk predicted Quotient Rapamycin RATs reduce Regular risk Risk estimation Ritonavir Rivers. Surface water Toxicity treat used to calculate water [DOI] 10.1016/j.scitotenv.2021.146303 PMC 바로가기 [Article Type] Article
Laboratory Diagnosis of SARS-CoV-2 PneumoniaReview Published on 2021-07-152022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acid antibody Antibody test category coronavirus disease-2019 COVID-19 Ct value diagnostic Efficacy effort form Health Human Immunoglobulin Infection measure NAAT pathogen identification Patient point of care testing Prevalence proliferation Rapid rapid antigen test RATs Region respiratory tract RT-LAMP RT-PCR SARS-CoV-2 serum specimen statistical Vaccine Viral protein Viral RNA viral spread virus Whole blood [DOI] 10.3390/diagnostics11071270 PMC 바로가기 [Article Type] Review
Food Enrichment with Glycyrrhiza glabra Extract Suppresses ACE2 mRNA and Protein Expression in Rats—Possible Implications for COVID-19글리 시르 시리 바 글라브라 추출물을 이용한 식품 농축 래트에서 ACE2 mRNA 및 단백질 발현을 억제합니다.Article Published on 2021-07-062022-08-31 Journal: Nutrients [Category] 유전자 메커니즘, 치료제, [키워드] ACE2 ACE2 expression ACE2 mRNA Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration aldosterone angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 animals body weight Brain Cell component coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 diet dose Effect enrichment enzyme Evidence experiment expression Extract FIVE food Gene Expression glycyrrhiza glycyrrhizin Hypothesis ileum independent independent of induce inhibitory activity Mild mineralocorticoid receptor organ organs outlined PCR Placebo present protein level RATs receptor reduce reduction respiratory resulting SARS-CoV-2 severe acute respiratory syndrome Coronavirus significant decrease small intestine Stress stress condition stress response Support suppressed susceptibility tissue tissues toll like receptor 4 virus [DOI] 10.3390/nu13072321 PMC 바로가기 [Article Type] Article
Characteristics of Angiotensin I-converting enzyme 2, type II transmembrane serine protease 2 and 4 in tree shrew indicate it as a potential animal model for SARS-CoV-2 infection안지오텐신 I- 결함 효소 2, Tree Shrew의 II 형 막 횡단 세린 프로테아제 2 및 4의 특성은 SARS-COV-2 감염에 대한 잠재적 인 동물 모델로 나타납니다.Research Article Published on 2021-07-062022-09-10 Journal: Bioengineered [Category] 유전자 메커니즘, 치료기술, [키워드] Abstract ACE2 ACE2 gene ACE2 receptor addition amino acids Analysis analyzed angiotensin angiotensin I-converting enzyme 2 animal model binding site cats CDS cloned enzyme esophagus expressed expression expression level expression levels followed by full-length high expression level Human information intestine kidney liver lung mechanism mice organ organs Phylogenetic analysis predicted RATs receptor reported SARS-CoV-2 SARS-COV-2 infection sequenced Serine significantly higher tissue expression TMPRSS2 TMPRSS4 transmembrane serine protease Tree shrew type II transmembrane serine protease various tissue various tissues [DOI] 10.1080/21655979.2021.1940072 PMC 바로가기 [Article Type] Research Article