Humoral and cellular immune response to severe acute respiratory syndrome coronavirus-2 vaccination in haemodialysis and kidney transplant patients혈액 투석 및 신장 이식 환자에서 중증 급성 호흡기 증후군 코로나바이러스-2 백신 접종에 대한 체액 및 세포 면역 반응Review Published on 2022-01-012022-09-12 Journal: Nephrology (Carlton, Vic.) [Category] SARS, 진단, [키워드] acute respiratory syndrome article Cellular immune response clinical immunology Cohort conducted confounders Coronavirus-2 country COVID-19 disease eligible ESRD excluded Follow-up General population group Haemodialysis Haemodialysis patient healthy control healthy controls humoral immune IMPROVE kidney kidney transplant Kidney transplantation Meta-analysis meta-regression outcome Patient patients proportion proportions ranged renal renal replacement therapy reported Responder response SARS-CoV-2 searched significantly lower vaccination Vaccines [DOI] 10.1111/nep.13974 PMC 바로가기 [Article Type] Review
Remdesivir Use in the Setting of Severe Renal Impairment: A Theoretical Concern or Real Risk?심각한 신장 장애 상황에서 렘데시비르 사용: 이론적 우려 또는 실제 위험?Article Published on 2021-12-062022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 치료제, [키워드] Acute kidney injury adverse event adverse events AEs analyzed approved benefit concern controls coronavirus disease Coronavirus disease 2019 COVID-19 creatinine creatinine clearance Elevation elevations evaluated hepatotoxicity hospitalized patients incidence liver Liver function test Mortality nephrotoxicity not significantly different occurred Older Patient patients RDV Remdesivir renal renal impairment renal impairment. renal replacement therapy replacement therapy reported retrospective Safe serum creatinine setting severe renal impairment significantly SRI theoretical risk Toxicity US FDA while [DOI] 10.1093/cid/ciaa1851 PMC 바로가기 [Article Type] Article
Peripheral oxygen saturation to inspiratory oxygen fraction ratio-based identification of critically ill coronavirus disease patients for early therapeutic interventionsObservational Study Published on 2021-12-012022-10-05 Journal: Journal of anesthesia [Category] SARS, 임상, [키워드] Admission age albumin Antiviral assist blood test C-reactive protein Characteristics clinical setting clinician conducted coronavirus disease COVID-19 COVID-19 severity Critically ill D-dimer determine diagnosed with COVID-19 died Early identification examined extracorporeal membrane oxygenation fraction groups interquartile range invasive Japan Kyoto laboratory data lactate dehydrogenase Mild moderate mortality rate outcome oxygen oxygen saturation Patient peripheral positive pressure ventilation reducing renal replacement therapy respiratory rate retrospective severe COVID-19 severity SF ratio significantly lower single-center SpO2/FiO2 SpO2/FiO2. the patient therapeutic intervention therapeutic interventions turn two group university [DOI] 10.1007/s00540-021-02986-w PMC 바로가기 [Article Type] Observational Study
Interpreting serum procalcitonin in COVID-19 patients undergoing renal replacement therapyShort communication Published on 2021-12-012022-10-05 Journal: Journal of global antimicrobial resistance [Category] SARS, 바이오마커, [키워드] antimicrobial Bacterial Continuous venovenous haemofiltration COVID-19 COVID-19 patient Interpreting procalcitonin renal replacement therapy serum [DOI] 10.1016/j.jgar.2021.09.014 [Article Type] Short communication
Association of early positive end-expiratory pressure settings with ventilator-free days in patients with coronavirus disease 2019 acute respiratory distress syndrome: A secondary analysis of the Practice of VENTilation in COVID-19 studyObservational Study Published on 2021-12-012022-10-05 Journal: European journal of anaesthesiology [Category] SARS, 임상, [키워드] 95% confidence interval Acute kidney injury acute respiratory distress AKI Analysis ARDS association Cohort cohorts conducted confounding factor coronavirus disease COVID-19 COVID-19 ARDS patients fixed had no ICU incidence invasive ventilation median Mortality Netherland network Organ failure outcome outcomes parameter Patient PEEP Positive end-expiratory pressure Practice Primary outcome propensity score matching Registered renal replacement therapy RRT secondary setting syndrome the median Ventilated ventilator ventilator-free day VFD [DOI] 10.1097/EJA.0000000000001565 PMC 바로가기 [Article Type] Observational Study
Clinical Characteristics, Complications and Outcomes of Patients with Severe Acute Respiratory Distress Syndrome Related to COVID-19 or Influenza Requiring Extracorporeal Membrane Oxygenation—A Retrospective Cohort StudyArticle Published on 2021-11-212022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] 113 patient acute respiratory distress age ARDS bleeding bleeding event Characteristics Charlson Comorbidity Index clinical Clinical characteristics Clinical outcome complex Complication consecutive patient coronavirus disease COVID-19 disease severity ECMO Extracorporeal female Germany ICU Influenza influenza pandemic invasive IQR membrane Mortality multiple organ failure outcome Oxygenation P/F ratio parameter Patient patients with COVID-19 renal replacement therapy respiratory Retrospective analysis SARS-CoV-2 severe ARDS SOFA score syndrome therapy thrombosis treated Treatment two group university utilised VV-ECMO with COVID-19 [DOI] 10.3390/jcm10225440 PMC 바로가기 [Article Type] Article
Clinical characteristics and outcomes of COVID-19 patients admitted to the intensive care unit during the first year of the pandemic in Brazil: a single center retrospective cohort studyOriginal Article Published on 2021-11-192022-10-31 Journal: Einstein [Category] COVID-19, SARS, [키워드] age assessment Betacoronavírus Betacoronavirus Brazil Characteristics Charlson Comorbidity Index clinical Clinical characteristics cohort study Comorbidity conducted Coronavírus coronavirus Coronavirus infections COVID-19 COVID-19 patient critical care outcomes died discharged exhibited extracorporeal membrane oxygenation failure hospital hospital discharge Hospital stay identify in-hospital mortality Infecções por coronavírus intensive care intensive care units interquartile range mechanical ventilation morbidity and mortality Mortalidade Mortality nasal non-survivor Non-survivors Noninvasive ventilation Older organ support outcome outcomes Oxigenação por membrana extracorpórea pacientes com COVID-19 pandemic Patient patients with COVID-19 Physiology predictor prolonged intensive care renal renal replacement therapy resource Respiração artificial Respiration, artificial Resultados de cuidados críticos retrospective cohort study SARS-CoV-2 score severe COVID-19 single center single-center study period Support survivor Survivors Unidades de terapia intensiva Ventilação não invasiva with COVID-19 [DOI] 10.31744/einstein_journal/2021AO6739 PMC 바로가기 [Article Type] Original Article
Kinetics of antibody response in critically ill patients with Middle East respiratory syndrome and association with mortality and viral clearanceArticle Published on 2021-11-192022-10-29 Journal: Scientific Reports [Category] COVID-19, MERS, [키워드] 95% CI Admission admitted to ICU antibody Antibody Response Antigen assessment association blood sample clearance coated with collected Corticosteroids Critically ill Critically ill patient Diseases ELISA enzyme-linked immunosorbent failure faster ICU IgG antibody immunology Immunotherapy implication invasive ventilation Kinetics lower mortality median MERS MERS patient MERS-CoV MERS-CoV RNA MERS-CoV S1 Middle East Mortality onset of symptom optical Pathogenesis Patient renal replacement therapy rRT-PCR significantly increased Signs and symptoms SOFA study cohort syndrome vasopressors viral clearance [DOI] 10.1038/s41598-021-01083-y PMC 바로가기 [Article Type] Article
Risk Factors for Invasive Aspergillosis in Patients Admitted to the Intensive Care Unit With Coronavirus Disease 2019: A Multicenter Retrospective StudyMedicine Published on 2021-11-162022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] 95% CI admitted to ICU adult COVID-19 patient Analysis analyzed aspergillosis CAPA characterized China CIs clinical criteria clinical variables conducted confidence interval coronavirus disease corticosteroid treatment COVID-19 COVID-19 mortality COVID-19 patient Critically ill patient daily dose demographic diagnosed Diagnosis dosage Factor hazard ratio hospital HRs ICU ICUs identify increased risk information intensive care unit Invasive mechanical ventilation Invasive pulmonary aspergillosis IPA life-threatening likelihood median Methylprednisolone Mortality Occurrence outcome Patient receive renal replacement therapy retrospective cohort study risk factor secondary bacterial infection significantly symptom onset thrombocytopenia Vasopressor with COVID-19 [DOI] 10.3389/fmed.2021.753659 PMC 바로가기 [Article Type] Medicine
Handling oxygenation targets in ICU patients with COVID-19-Protocol and statistical analysis plan in the HOT-COVID trialHOT-COVID 임상시험에서 COVID-19-Protocol 및 통계 분석 계획이 있는 ICU 환자의 산소화 목표 처리Article Published on 2021-11-012022-09-11 Journal: Acta Anaesthesiologica Scandinavica [Category] 임상, 치료제, [키워드] absolute increase Admission Affect analyses arterial partial pressure of oxygen cognitive coronavirus disease COVID-19 COVID-19 patient days alive defined detect disease dosage Follow-up Health hospital hypoxaemic respiratory failure hypoxia ICU ICU admission ICU patient ICU Patients include intensive care intensive care unit intensive care units interim analysis investigator-initiated kPa life lower airway lower airways lung Lungs management mechanical ventilation Mortality multicentre outcome oxygen Oxygenation parallel-group partial pressure Patient Patient management patients Pragmatic Primary outcome protocol Pulmonary function Randomized renal replacement therapy replacement therapy Respiratory failure secondary Secondary outcomes Serious Adverse Event Serious Adverse Events statistical analysis Statistical analysis plan supplemental oxygen Supportive treatment target therapy Trial Vasoactive with COVID-19 [DOI] 10.1111/aas.13956 PMC 바로가기 [Article Type] Article