Efficient and effective single-step screening of individual samples for SARS-CoV-2 RNA using multi-dimensional pooling and Bayesian inference다차원 풀링 및 베이지안 추론을 사용하여 SARS-CoV-2 RNA에 대한 개별 샘플의 효율적이고 효과적인 단일 단계 스크리닝Life Sciences–Chemistry interface Published on 2021-06-162022-09-10 Journal: Journal of the Royal Society Interface [Category] MERS, SARS, 진단, 치료기술, [키워드] Algorithm Bayesian Bayesian inference Chain Reaction COVID-19 pandemic Critical detect effective efficient faster Health implementation Infectious disease Metrics molecular molecular assays Monte Carlo non-adaptive screening outcome Pathogens polymerase chain polymerase chain reaction pooling positive result protocol public health emergency Rapid required resource reverse transcription RT-PCR SARS-CoV-2 SARS-CoV-2 RNA scaled up screened screening strategy Sensitivity and specificity specimen storage Support Surveillance sustained tested Threats undergo Viral viral pathogen viral pathogens Volume widespread [DOI] 10.1098/rsif.2021.0155 PMC 바로가기 [Article Type] Life Sciences–Chemistry interface
Prevalence of Clinical and Subclinical Myocarditis in Competitive Athletes With Recent SARS-CoV-2 Infection Results From the Big Ten COVID-19 Cardiac RegistryBig Ten COVID-19 Cardiac Registry의 최근 SARS-CoV-2 감염 결과가 있는 경쟁 선수의 임상 및 무증상 심근염의 유병률Observational Study Published on 2021-05-272022-09-10 Journal: JAMA Cardiology [Category] Fulltext, SARS, 임상, 진단, 치료기술, [키워드] Abnormalities Affect aggregate approach approaches athlete Big Ten Conference cardiac Chain Reaction clinical cohort study Complete COVID-19 COVID-19 infection COVID-19 infections death demonstrated determine diagnosed diagnosed with COVID-19 diagnostic diagnostic testing evaluated exposure Factor finding gadolinium implication Importance increase in Inflammation Interpretation magnetic resonance imaging measure men Myocardial inflammation myocarditis objective Observational data occur participant performed Point polymerase chain polymerase chain reaction Polymerase chain reaction testing Prevalence principal investigator Principal Investigators Program recent registry Relevance reported Result Safe SARS-CoV-2 Screening screening strategy setting Subclinical Symptom symptomatic and asymptomatic testing protocol testing protocols unique universities utility Variability variable was determined was performed were recorded with COVID-19 [DOI] 10.1001/jamacardio.2021.2065 PMC 바로가기 [Article Type] Observational Study
Outcomes of patients with end stage kidney disease on dialysis with COVID-19 in Abu Dhabi, United Arab Emirates; from PCR to antibody아랍에미리트 아부다비에서 코로나19 투석을 받은 말기 신장질환 환자의 결과; PCR에서 항체로Research Published on 2021-05-262022-09-01 Journal: BMC Nephrology [Category] SARS, 진단, 치료제, [키워드] Abu addition age antibody Antibody Response Antibody responses Asymptomatic average average age camostat characteristics of patient Cohort combinations Community Comorbidities concerning Contact contributed cough country COVID 19 COVID-19 COVID-19 infection COVID19 Critical care defined demographics develop diabete diabetes dialysis disease drug End stage kidney disease examined family Favipiravir Haemodialysis heart disease Hydroxychloroquine hypertension ICU IgG antibody individual infected individual infected individuals Infection Ischaemic heart disease Isolation Kidney disease lack Local Lopinavir lower mortality majority male median time Mild Mild disease Mortality Most patients negative PCR test outcome overall mortality Patient patients PCR PCR positive patient PCR positivity PCR tests performed Population positive patient positive patients presenting symptoms Rapid required Result Ritonavir Screening screening strategy serology source of infection spread of COVID-19 steroid Steroids study period subset symptomatic tested the antibody response Tocilizumab Viral viral clearance was performed were used with COVID-19 [DOI] 10.1186/s12882-021-02378-y PMC 바로가기 [Article Type] Research
Saliva Exhibits High Sensitivity and Specificity for the Detection of SARS-COV-2Review Published on 2021-05-202022-11-01 Journal: Diseases [Category] COVID-19, [키워드] approved calculated calculator Clinical studies COVID-19 COVID-19 pandemic Cross-infection detectable detection Diagnosis diagnostic effective Evidence FDA Infection invasive involved Non-invasive offer polymerase chain polymerase chain reaction risk Saliva saliva specimens SARS-CoV-2 School screening strategy sensitivity Sensitivity and specificity specificity specimen sputum stability widespread [DOI] 10.3390/diseases9020038 PMC 바로가기 [Article Type] Review
False Negative Mitigation in Group Testing for COVID-19 ScreeningMedicine Published on 2021-05-102022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] applied average COVID-19 COVID-19 screening diagnostic false-negative false-negative mitigation false-negative rate group Group testing groupMix identify increase individual infected individual Laboratory lockdown restriction Mitigation negative pool testing Prevent reduce replicate resources RT-PCR SARS-CoV-2 Screening screening strategy sensitivity significantly Spread Testing uninfected Viral load virus [DOI] 10.3389/fmed.2021.661277 PMC 바로가기 [Article Type] Medicine
Screening for Gestational Diabetes during the COVID-19 Pandemic—Current Recommendations and Their ConsequencesCOVID-19 팬데믹 기간 동안 임신성 당뇨병 검사 - 현재 권장 사항 및 그 결과Review Published on 2021-04-152022-09-10 Journal: Medicina [Category] MERS, SARS, 치료기술, [키워드] Complication consequence COVID-19 COVID-19 pandemic current diabetes diagnosed Evidence fetus Gestational diabetes gestational diabetes mellitus guidelines Impact International lead management morbidity mother perinatal morbidity Pregnancy reduced risk Risk factors Screening screening programs screening strategy treated uniformity women [DOI] 10.3390/medicina57040381 PMC 바로가기 [Article Type] Review
Increased SARS-CoV-2 Testing Capacity with Pooled Saliva Samples혼합된 타액 샘플로 SARS-CoV-2 검사 용량 증가Dispatch Published on 2021-04-012022-09-10 Journal: Emerging Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] 2019 novel coronavirus disease acute respiratory syndrome acute respiratory syndrome coronavirus analyzed Capacity coronavirus coronavirus disease COVID-19 diagnostics feasibility Increased Prevalence respiratory respiratory infections Saliva saliva samples Sample SARS-CoV-2 Screening screening strategy sensitivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Support Testing virus viruses zoonoses [DOI] 10.3201/eid2704.204200 PMC 바로가기 [Article Type] Dispatch
Urgent/emergency surgery during COVID-19 state of emergency in Portugal: a retrospective and observational studyObservational Study Published on 2021-03-012022-10-05 Journal: Brazilian journal of anesthesiology (Elsevier) [Category] 임상, [키워드] 2020 COVID-19 pandemic Admission affected analysed Care changed Characteristics conducted correlated country COVID-19 COVID-19 case COVID-19 diagnostic testing COVID-19 pandemic COVID-19 patients Department diagnostic Efficiency Emergency emergency service Emergency service, hospital Evolution examined good quality growth health care facility homologous hospital less medical record Mortality mortality rate National no difference number of infected operative pandemic Patient Population Portugal preoperative reduce reduction in reported retrospective SARS-CoV-2 virus screening strategy surgical Surgical procedures, operative. Volume [DOI] 10.1016/j.bjane.2021.01.003 PMC 바로가기 [Article Type] Observational Study
Importance of Preoperative Screening Strategies for Coronavirus Disease 2019 in Patients Undergoing Cesarean Sections: A Retrospective, Large Single-Center, Observational Cohort StudyArticle Published on 2021-02-222022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] Admission analyzed Cesarean section Chest radiography coronavirus disease correlation COVID-19 COVID-19 outbreak epidemiological evaluated Importance Infection Nosocomial infection Operating room pandemic parturient Patient PCR performed Personal protective equipment positive PPE preoperative questionnaire risk of COVID-19 RT–PCR RT–PCR Screening screening process screening strategy Strategy Symptom symptomatic [DOI] 10.3390/jcm10040885 PMC 바로가기 [Article Type] Article
A novel screening strategy of anti-SARS-CoV-2 drugs via blocking interaction between Spike RBD and ACE2Spike RBD와 ACE2 간의 상호 작용 차단을 통한 항 SARS-CoV-2 약물의 새로운 스크리닝 전략Article Published on 2021-02-012022-08-31 Journal: Environment international [Category] MERS, SARS, 치료제, [키워드] ACE2 activity angiotensin angiotensin converting enzyme anti-SARS-CoV-2 Anti-SARS-CoV-2 drugs screening strategy binding binding energy blockade Blockade mechanism Compound compounds Corona drug drug design Drug screening druggability eight enzyme exhibited hACE2 hesperidin highest human angiotensin converting enzyme 2 information Interaction investigated mechanism overcome pandemic RBD Receptor binding domain required S RBD SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2 Spike RBD screening strategy spike Spread Structure Structure-activity relationship structures therapy Virus Disease [DOI] 10.1016/j.envint.2020.106361 PMC 바로가기 [Article Type] Article