Catching COVID: Engineering Peptide-Modified Surface-Enhanced Raman Spectroscopy Sensors for SARS-CoV-2코로나 잡기: SARS-CoV-2용 펩티드 수정 표면 강화 라만 분광기 센서 엔지니어링Article Published on 2021-09-242022-09-11 Journal: ACS Sensors [Category] SARS, 변종, 치료기술, [키워드] Accuracy ACE2 albumin amplification angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 biomimetic biosensor bovine bovine serum albumin complex COVID-19 Engineering generate globe highlighting IMPROVE limit of detection peptide peptide-based peptides probe provide quantification quantitative assay Raman spectroscopy SARS-CoV-2 selective selectivity sensor SERS serum albumin specificity Spectroscopy Spike protein the spike protein unique variants Viral protein Viral proteins virus viruses [DOI] 10.1021/acssensors.1c01344 PMC 바로가기 [Article Type] Article
Hypophosphatemia is an independent risk factor for AKI among hospitalized patients with COVID-19 infectionResearch Article Published on 2021-09-192022-10-28 Journal: Renal failure [Category] COVID-19, SARS, [키워드] 95% CI Acute kidney injury Admission age AKI albumin C-reactive protein clinical COVID-19 COVID-19 infection COVID-19 patient Cox regression analysis CRP decrease dysfunction eight enrolled evaluated Follow-up hospital Hospitalization hospitalized COVID-19 hospitalized patient hypophosphate hypophosphatemia ICU ICU Patients incidence increased risk independent risk factor Infection laboratory parameter lactate dehydrogenase LDH Lymphocyte count male non-ICU non-ICU patient occurred Older Patient patients patients hospitalized Pearson phosphate Platelet positively correlated procalcitonin Prothrombin time proximal proximal tubule renal renal function renal tubular Result Retrospective study risk factor Risk factors serum serum albumin subgroup analysis systemic urea uric acid Urine Volume were recorded with COVID-19 Wuhan, China [DOI] 10.1080/0886022X.2021.1979039 PMC 바로가기 [Article Type] Research Article
Long-term clinical and biochemical residue after COVID-19 recoveryOriginal Research Article Published on 2021-09-122022-10-31 Journal: Egyptian Liver Journal [Category] COVID-19, [키워드] 95% CI addressed age alkaline phosphatase ALP ALT alteration Analysis AOR Aspartate aminotransferase AST biochemical Blood urea nitrogen C-reactive protein Care Clinical sign Concentration consequence coronavirus disease COVID-19 CRP D-dimer detect elevated erythrocyte sedimentation ESR Follow-up Haemoglobin Health long-term consequences majority male polymerase chain post-COVID-19 predictor proportion questionnaire Regression residue Result RT-PCR SARS-CoV-2 serum serum albumin significantly survivor Symptom Systemic changes Systolic blood pressure Trial uric acid was reduced [DOI] 10.1186/s43066-021-00144-1 PMC 바로가기 [Article Type] Original Research Article
Clinical and Laboratory Predictors of Mortality in COVID-19 Infection: A Retrospective Observational Study in a Tertiary Care Hospital of Eastern IndiaInternal Medicine Published on 2021-09-022022-10-31 Journal: Cureus [Category] COVID-19, [키워드] adjusted odds ratio adverse outcome age albumin Analysis analyzed Antigen blood urea Care carried Chronic kidney disease CKD clinical college confounder cough COVID-19 COVID-19 case covid-19 outcome predictor D-dimer death Dyspnea Factor female ferritin Final high risk highest hospital identification India Infection Inflammatory marker lab laboratory parameter leukocyte logistic regression model male management marker material Medical comorbidities Medical Science morbidity and mortality Mortality NLR objective outcome overall case-fatality rate Patient patients with COVID-19 Patna polymerase chain positive predict presenting raised Regression model Result risk serum albumin severe COVID-19 disease significantly Stata Corp Station subset Tertiary USA was performed [DOI] 10.7759/cureus.17660 PMC 바로가기 [Article Type] Internal Medicine
Humoral Response after SARS-CoV-2 mRNA Vaccination in a Cohort of Hemodialysis Patients and Kidney Transplant Recipients혈액투석 환자와 신장 이식 환자 집단에서 SARS-CoV-2 mRNA 백신 접종 후 체액 반응Article Published on 2021-09-012022-09-11 Journal: Journal of the American Society of Nephrology : JA [Category] SARS, 치료기술, [키워드] albumin anti-SARS-CoV-2 antibody antibody Antibody Response Antibody titer Antibody titers arbitrary unit BNT162b2 CKD clinical trial clinical trials controls COVID-19 COVID-19 vaccination detected antibody HBV healthy controls Hemodialysis hemodialyzed hepatitis B Hepatitis B vaccination humoral Humoral response Immunocompromised Immunosuppressant immunosuppressants inhibited injection interquartile range IQR kidney transplant kidney transplant recipients kinetic lowest mRNA mRNA vaccine mRNA vaccines parameters Patient peaked Pfizer/BioNTech Population positive positively correlated postvaccination Prevent receiving recipient recorded reduced response response to vaccination SARS-CoV-2 Seroconversion serological response serum albumin Seven therapy Transplant uremic vaccination Vaccine were excluded [DOI] 10.1681/ASN.2021040490 PMC 바로가기 [Article Type] Article
COVID-19 Vaccines in Patients with Maintenance HemodialysisReview Published on 2021-08-122022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] addition age Analysis anti-SARS-CoV-2 antibody antibody Antibody detection antibody formation Antibody Response caused Comorbidities concerning contagious COVID-19 COVID-19 infection COVID-19 pandemic COVID-19 vaccination COVID-19 vaccines death dialysis disease dosage Effectiveness elicited Factors General population greater healthy control Hemodialysis hygiene immune response immune responses Immunity immunization immunosuppressive Infection information Isolation maintenance Measures Older age Patient populations Protective receiving remains uncertain repeated risk of COVID-19 serum albumin social distancing therapy timepoints vaccination Vaccine Vaccine development Vaccines [DOI] 10.3390/jpm11080789 PMC 바로가기 [Article Type] Review
Clinical characteristics and risk factors for mortality in COVID-19 inpatients in Birjand, Iran: a single-center retrospective studyResearch Published on 2021-07-212022-10-31 Journal: European Journal of Medical Research [Category] COVID-19, SARS, [키워드] affected analyses Analysis association C-reactive protein Characteristics Chi-square clinical Clinical characteristics clinical parameter clinician Comorbidities Comorbidity conducted coronavirus disease COVID-19 COVID-19 disease COVID-19 patient Cox model Data analysis death died discharged electronic medical records epidemiological evaluate Fisher’s exact test groups helping hemoglobin hypertension Inpatient Kidney function Laboratory parameters liver lymphocyte Lymphocyte count lymphocyte counts management Mortality mortality rate non-survivor outcome oxygen saturation Patient patients patients with comorbidity Platelet Prognosis progression Result Retrospective study risk risk factor risk factors of death risk of death serum albumin Significant single-center single-center study statistically significant survival Survival model survivor Treatment variables was used were used [DOI] 10.1186/s40001-021-00553-3 PMC 바로가기 [Article Type] Research
Validation of a Prospective Urinalysis-Based Prediction Model for ICU Resources and Outcome of COVID-19 Disease: A Multicenter Cohort StudyArticle Published on 2021-07-092022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] abnormality Acute kidney injury Admission Algorithm categories clinical outcomes Course COVID-19 death disease disease severity elevated eligible Enrollment Extra-corporeal membrane oxygenation hospital Hospital admission Hypothesis ICU ICU admission ICU resources mechanical ventilation Model Mortality outcome patients pilot study Post-mortem predict prediction preventive measures Prospective renal renal replacement therapy resource risk risk stratification SARS-CoV-2 screened serum albumin significantly the primary endpoint time Urinalysis Urine validation [DOI] 10.3390/jcm10143049 PMC 바로가기 [Article Type] Article
Bovine Serum Albumin-Coated Niclosamide-Zein Nanoparticles as Potential Injectable Medicine against COVID-19Article Published on 2021-07-072022-10-30 Journal: Materials [Category] COVID-19, [키워드] addition affected albumin anti-SARS-CoV-2 vaccination bovine BSA coated with Combination conditions country COVID-19 Cytokine storm drug effective encapsulate endothelial endothelial glycocalyx damage FDA-approved drugs General population hybrid drug Immunity IMPROVE Infection less medication Medicine mortality rates nanoparticle NIC niclosamide pandemic Potential reduction in resulting serum serum albumin significantly stability sustained the SARS-CoV-2 virus treating COVID-19 patient virus-infected cells Zein [DOI] 10.3390/ma14143792 PMC 바로가기 [Article Type] Article
Development and Validation of a Multivariable Predictive Model for Mortality of COVID-19 Patients Demanding High Oxygen Flow at Admission to ICU: AIDA ScoreClinical Trial Published on 2021-06-302022-10-04 Journal: Oxidative Medicine and Cellular Longevity [Category] MERS, SARS, 임상, [키워드] 95% CI addition Admission admitted to ICU age AIDA Analysis coefficient Cohort Comorbidity Coronary artery disease COVID-19 COVID-19 disease COVID-19 patient Critical care D dimer development diabete external validation Final Flow Health high risk hypertension ICU IL-6 management material mechanical ventilation men Model moderate Mortality mortality risk Most patient multivariable multivariate model Negative predictive value outcome Patient patients Positive predictive value Predictive resources Result risk Risk category risk factor score sensitivity serum albumin severe ARDS significant variable specificity Stratification study population treated utility validation validation cohort validation cohorts were used women [DOI] 10.1155/2021/6654388 PMC 바로가기 [Article Type] Clinical Trial