Cardiometabolic risks of SARS-CoV-2 hospitalization using Mendelian RandomizationArticle Published on 2021-04-122022-10-04 Journal: Scientific Reports [Category] MERS, 유전자 메커니즘, [키워드] 95% CI applied association associative BMI Cardiology cardiometabolic condition COVID-19 COVID-19 hospitalization demonstrated diabete diastolic Diseases European Evidence genetics GWAS GWAS summary statistics Hospitalization Inference inferences IVW large sample limitation Medical research Population populations pulse Pulse pressure reduce risk Risk factors robust SARS-CoV-2 severe COVID-19 illness suggested Systolic blood pressure Treatment Type with COVID-19 [DOI] 10.1038/s41598-021-86757-3 PMC 바로가기 [Article Type] Article
Characteristics and Disease Severity of US Children and Adolescents Diagnosed With COVID-19Research Published on 2021-04-092022-10-29 Journal: JAMA Network Open [Category] COVID-19, MERS, SARS, [키워드] Adolescent association Clinical characteristics cohort study COVID-19 Hospitalized Pediatric patient Release severe COVID-19 illness with COVID-19 [DOI] 10.1001/jamanetworkopen.2021.5298 PMC 바로가기 [Article Type] Research
Functional outcomes in the inpatient rehabilitation setting following severe COVID-19 infectionResearch Article Published on 2021-03-312022-10-28 Journal: PLoS ONE [Category] COVID-19, MERS, [키워드] Admission age balance Care Clinical characteristics cohort of patient communication Complication consecutive patient COVID-19 demographics demonstrated discharge discharged home domain examined exhibited functional gait speed Hearing highlighting hospital Hospitalization Hospitalized impairment Intubated male measure measurement memory Meter minute objective outcome Patient patient population rehabilitation Result retrospective risk scale severe COVID-19 illness Severe COVID-19 Infection significantly speech study population System Test transfer were assessed with COVID-19 [DOI] 10.1371/journal.pone.0248824 PMC 바로가기 [Article Type] Research Article
Anemia is associated with severe illness in COVID-19: A retrospective cohort studyObservational Study Published on 2021-03-012022-10-04 Journal: Journal of medical virology [Category] 임상, [키워드] 95% confidence interval addition Admission aggravate analyzed Anemia Awareness baseline Brain C-reactive protein Characteristics clinical Clinical characteristics Cohort collected Comorbidity coronavirus disease COVID-19 COVID-19 patient creatinine CRP D-dimer demonstrated Disease progression Dyspnea elevated erythrocyte sedimentation rate evaluate Factor Healthcare professional hemoglobin independent risk factor Laboratory Level multivariable logistic regression Myoglobin Ninth Patient PCT peptide procalcitonin Prognosis proportion recruited respiratory diseases retrospective retrospective cohort study risk risk factor severe COVID-19 illness severe illness severity severity of COVID-19 significantly higher single-center univariable urea nitrogen Wuhan [DOI] 10.1002/jmv.26444 PMC 바로가기 [Article Type] Observational Study
Epidemiological characteristics of patients with severe COVID-19 infection in Wuhan, China: evidence from a retrospective observational studyObservational Study Published on 2021-01-232022-10-05 Journal: International Journal of Epidemiology [Category] 임상, [키워드] 95% CI 95% confidence interval acute respiratory syndrome advanced age age analysed analyses cardiovascular disease characteristics of patient China chronic disease CIs Clinical characteristics Clinical data clinical monitoring coronavirus COVID-19 Critical Critical case Critically ill critically ill patients death diabete died discharged Evidence Factor help hospital hypertension identifying Infection IQR Logistic male Male sex median Mortality New coronavirus Older oxygen Oxygen therapy pandemic Patient peaked Pneumonia populations receiving Respiratory disease retrospective risk risk factor Risk factors SARS-CoV-2 severe COVID-19 illness Severe COVID-19 Infection severity susceptible Treatment with COVID-19 Wuhan [DOI] 10.1093/ije/dyaa180 PMC 바로가기 [Article Type] Observational Study
Severely ill COVID-19 patients display impaired exhaustion features in SARS-CoV-2-reactive CD8 + T cellsResearch Articles Published on 2021-01-212022-10-28 Journal: Science Immunology [Category] COVID-19, [키워드] Analysis anti-apoptotic CD8 Cell COVID-19 patient cytotoxicity disease dominant enrichment feature Frequency Glycolysis healthy control healthy subject healthy subjects Inflammatory Influenza memory Mild molecular NF-κB signaling Pathways Patient reactive respiratory syncytial virus respond response robust SARS-CoV-2 SARS-COV-2 infection severe COVID-19 illness severe disease single-cell single-cell transcriptome subset T cell T cell memory T cell response T cells transcript two group [DOI] 10.1126/sciimmunol.abe4782 PMC 바로가기 [Article Type] Research Articles
Thrombocytopenia Is Associated with COVID-19 Severity and Outcome: An Updated Meta-Analysis of 5637 Patients with Multiple Outcomes혈소판 감소증은 COVID-19 심각도 및 결과와 관련이 있습니다: 다중 결과를 가진 5637명의 환자에 대한 업데이트된 메타 분석Review Published on 2021-01-042022-09-12 Journal: Laboratory medicine [Category] MERS, 진단, [키워드] 95% CI 95% confidence interval acute respiratory distress Admission Analysis association binary outcome coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic Endpoint event explain high mortality hospitalized patient incidence indicated intensive care mean difference Meta-analysis Mortality Multiple nonsurvivors Odds ratio outcome outcomes Patient patients with COVID-19 Platelet Prognosis progression risk SARS-CoV-2 severe COVID-19 illness severity significantly suggested syndrome thrombocytopenia with COVID-19 [DOI] 10.1093/labmed/lmaa067 PMC 바로가기 [Article Type] Review
Cancer patients and COVID-19: Mortality, serious complications, biomarkers, and ways forward암 환자와 COVID-19: 사망률, 심각한 합병증, 바이오마커, 그리고 앞으로의 길Review Published on 2021-01-012022-09-11 Journal: Cancer treatment and research communications [Category] MERS, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus benefit Biomarkers C-reactive protein Cancer cancer patient Cancer patients complications consequence coronavirus COVID-19 COVID-19 illness COVID-19 infection Evidence evidence of hematological high risk Immunocompromised interleukin interleukin-6 leads malignancies malignancy management Mortality outcome pandemic Patient poor prognosis predictor preliminary evidence respiratory risk SARS-CoV-2 Sever acute respiratory syndrome coronavirus 2. severe complication severe complications severe COVID-19 illness severity susceptible therapeutic interventions Treatment virus with COVID-19 [DOI] 10.1016/j.ctarc.2020.100285 PMC 바로가기 [Article Type] Review
Association Between Early Treatment With Tocilizumab and Mortality Among Critically Ill Patients With COVID-19토실리주맙의 조기 치료와 COVID-19 중환자의 사망률 사이의 연관성Article Published on 2021-01-012022-09-12 Journal: JAMA Internal Medicine [Category] 진단, [키워드] 30-Day mortality 95% CI adjust Admission Analysis baseline Characteristics cohort study collected coronavirus disease COVID-19 Cox regression model Critically ill patient death decrease died Follow-up fraction groups hazard ratio hospital HRs Hypoxemia ICU ICU admission ICUs Ill IMPROVE in-hospital mortality include Inflammatory cytokine intensive care unit interleukin 6 receptor IQR lower risk male mechanical ventilation median median age monoclonal antibody Mortality multicenter cohort study outcome oxygen Patient patients treated Prevalence primary analysis Probability randomized clinical trial receive Research risk severe COVID-19 illness survival susceptible syndrome time Tocilizumab treated Treatment was used Weighting with COVID-19 [DOI] 10.1001/jamainternmed.2020.6252 PMC 바로가기 [Article Type] Article
Pandemic Perspective: Commonalities Between COVID-19 and Cardio-OncologyCardiovascular Medicine Published on 2020-12-042022-10-31 Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19, [키워드] Abnormalities ACE2 ACEIs addition addressed angiotensin receptor blocker antibody ARBs Cancer cardio-oncology Cardiomyopathy cardiovascular disease Coagulopathy commonality coronavirus disease COVID-19 COVID-19 pandemic culprit virus CVD cytokine release Cytokine release syndrome drug Endothelial dysfunction enzyme equity Health Health disparities higher risk highlight human cell implementation IMPROVE Inflammation inhibitor Interaction Ischemia learning management Myopericarditis overlap pandemic pathophysiology Patient Perspective profile receptor right ventricle risk factor severe COVID-19 illness similarity Telemedicine Therapies Toxicity use of corticosteroids ventricular [DOI] 10.3389/fcvm.2020.568720 PMC 바로가기 [Article Type] Cardiovascular Medicine