Why Females Do Better: The X Chromosomal TLR7 Gene-Dose Effect in COVID-19
여성이 더 잘하는 이유: 코로나19에서 X 염색체 TLR7 유전자 용량 효과
Immunology
[키워드] age
biallelic
caused
concerning
contribute
COVID-19
COVID-19 pandemic
COVID-19 treatment
dendritic cells
Effect
expression
Factor
female
gene-dose effect
Hypothesis
ICU
IFN
IFN pathway
IFN response
Immune cell
immune cells
Immunopathogenesis
inactivation
Infection
interferon
investigated
Male sex
modulation
Mortality
Pattern recognition
pattern recognition receptor
Pattern recognition receptors
plasmacytoid dendritic cell
plasmacytoid dendritic cells
Protective
responsible
SARS-CoV-2
severe COVID-19
severity
Sex difference
sex differences
sex hormone
Sex hormones
ssRNA
TLR
TLR7
TLR7 gene
Toll-like receptor
Treatment
type 1 interferon
Viral
viral infections
X chromosome
X chromosome inactivation escape
[DOI] 10.3389/fimmu.2021.756262 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2021.756262 PMC 바로가기 [Article Type] Immunology